2023
- Matsumoto M, Ohmura T, Hanibuchi Y, Ichimura-Shimizu M, Saijo Y, Ogawa H, Miyazawa R, Morimoto J, Tsuneyama K, Matsumoto M, Oya T. AIRE illuminates the feature of medullary thymic epithelial cells in thymic carcinoma. Cancer Med. 12(8) 9843-9848, 2023
- Sato S, Koyama K, Ogawa H, Murakami K, Imakura T, Yamashita Y, Kagawa K, Kawano H, Hara E, Nishioka Y. A novel BRD4 degrader, ARV-825, attenuates lung fibrosis through senolysis and antifibrotic effect. Respir Investig 61(6):781-792, 2023.
- Imakura T, Sato S, Koyama K, Ogawa H, Niimura T, Murakami K, Yamashita Y, Haji K, Naito N, Kagawa K, Kawano H, Zamami Y, Ishizawa K, Nishioka Y. A polo-like kinase inhibitor identified by computational repositioning attenuates pulmonary fibrosis. Respir Res 24(1):148, 2023.
- Shao W, Shimizu M, Ogawa H, Jin S, Sutoh M, Nakamura S, Onodera M, Tawara H, Toyohara S, Hokao R, Kudo Y, Oya T, Tsuneyama K. Establishment of repeated liver biopsy technique in experimental mice. Heliyon, 3;9(6):e16978, 2023
- Kakimoto T, Hosokawa M, Shimizu M, Ogawa H, Miyakami Y, Sumida S, Tsuneyama K, Accumulation of α-synuclein in hepatocytes in nonalcoholic steatohepatitis and its usefulness in pathological diagnosis, Pathol Res Pract, 247:154525, 2023
- Miyakami Y, Minamikawa T, Ogawa H, Shimizu M, Tsuneyama K. Definitive Confirmation of Erythropoietic Protoporphyria via Re-biopsy Three Years After Initial Liver Biopsy at Age 15. Cureus, 23;15(4):e38017, 2023
- Sumida S, Shimizu M, Miyakami Y, Kakimoto T, Kobayashi T, Saijo Y, Matsumoto M, Ogawa H, Oya T, Bando Y, Uehara H, Taira S, Shimada M, Tsuneyama K, Histological and immunohistochemical analysisof epithelial cells in epidermoid cysts in intrapancreatic accessory spleen. J Med Invest, 70(1,2), 2023
2022
1: Ichimura-Shimizu M, Tsuchiyama Y, Morimoto Y, Matsumoto M, Kobayashi T, Sumida S, Kakimoto T, Oya T, Ogawa H, Yamashita M, Matsuda S, Omagari K, Taira S, Tsuneyama K. A novel mouse model of non-alcoholic steatohepatitis suggests that liver fibrosis initiates around lipid-laden macrophages. American Journal of Pathology, Vol. 192 (1), pp.31-42, 2022
2: Minamikawa T, Hase E, Ichimura-Shimizu M, Morimoto Y, Suzuki A, Yasui T, Nakamura S, Tsutsui A, Takaguchi K, Tsuneyama K. Assessment of ultra-early-stage liver fibrosis in human non-alcoholic fatty liver disease by second-harmonic generation microscopy. Int J Mol Sci 23(6),3357, 2022
3. Ichimura-Shimizu M, Ishimaru S, Wai CYY, Minamikawa T, Tsunematsu T, Endo A, Kojima T, Matsumoto M, Kobayashi T, Sumida S, Kakimoto T, Miyakami Y, Ogawa H, Oya T, Tsuneyama K. Establishment of an epicutaneously sensitized murine model of shellfish allergy and evaluation of skin condition by raman microscopy. Appl Sci 12, 3566, 2022. https://doi.org/10.3390/app12073566
4. Yagi K, Sato Y, Sakaguchi S, Goda M, Hamano H, Aizawa F, Shimizu M, Inoue-Hamano A, Nishimori T, Tagi M, Kanno M, Matsuoka-Ando R, Yoshioka T, Matsubara Y, Izawa-Ishizawa Y, Shimizu R, Maruo A, Kuniki Y, Sakamoto Y, Itobayashi S, Zamami Y, Yanagawa H, Ishizawa K. A web-based survey of educational opportunities of medical professionals based on changes in conference design during the COVID-19 pandemic. Educ Inf Technol 18;1-16 2022
5:Ogawa H, Azuma M, Umeno A, Shimizu M, Murotomi K, Yoshida Y, Nishioka Y, Tsuneyama K. Singlet Oxygen -derived Nerve Growth Factor Exacerbates Airway Hyperresponsiveness in a Mouse Model of Asthma with Mixed Inflammation. Allergology International 71 :395-404,2022
6: Miyazaki K, Saito Y, Ichimura-Shimizu M, Imura S, Ikemoto T, Tokuda K, Okikawa S, Morine Y, Tsuneyama K, Shimada M. Endoplasmic reticulum stress response deficiency is a major cause of poor liver regeneration after partial hepatectomy in nonalcoholic steatohepatitis. J Hepatobiliary Pancreat Sci 2022 doi: 10.1002/jhbp.1142.
2021
1: Nakamura N, Yoshida K, Tsuda R, Murata M, Yamaguchi T, Suwa K, Ichimura M, Tsuneyama K, Matsuzaki K, Nakano T, Hirohara J, Seki T, Okazaki K, Gershwin ME, Naganuma M. Phospho-Smad3 signaling is predictive biomarker for hepatocellular carcinoma risk assessment in primary biliary cholangitis patients. Front Biosci (Landmark Ed). 2021 Dec 30;26(12):1480-1492.
2: Azuma YT, Fujita T, Izawa T, Hirota K, Nishiyama K, Ikegami A, Aoyama T, Ike M, Ushikai Y, Kuwamura M, Fujii H, Tsuneyama K. IL-19 Contributes to the Development of Nonalcoholic Steatohepatitis by Altering Lipid Metabolism. Cells. 2021 Dec 13;10(12):3513.
3: Ichimura-Shimizu M, Kageyama T, Oya T, Ogawa H, Matsumoto M, Sumida S, Kakimoto T, Miyakami Y, Nagatomo R, Inoue K, Cheng C, Tsuneyama K. Verification of the Impact of Blood Glucose Level on Liver Carcinogenesis and the Efficacy of a Dietary Intervention in a Spontaneous Metabolic Syndrome Model. Int J Mol Sci. 2021 Nov 27;22(23):12844.
4: Yamazaki M, Tomii N, Tsuneyama K, Takanari H, Niwa R, Honjo H, Kodama I, Arafune T, Makita N, Sakuma I, Dobrev D, Nattel S, Tsuji Y. Rotors anchored by refractory islands drive torsades de pointes in an experimental model of electrical storm. Heart Rhythm. 2021 Oct 20:S1547-5271(21)02239-6.
5: Hatta H, Nishida T, Minamisaka T, Tsuneyama K, Imura J. Utility of Ethylene-Diamine-Tetraacetic Acid Buffer Solution With Boric Acid for Immunostaining of Specimens Stored for an Extended Period. Cureus. 2021 Aug 29;13(8):e17549.
6: Valencia JC, Erwin-Cohen RA, Clavijo PE, Allen C, Sanford ME, Day CP, Hess MM, Johnson M, Yin J, Fenimore JM, Bettencourt IA, Tsuneyama K, Romero ME, Klarmann KD, Jiang P, Bae HR, McVicar DW, Merlino G, Edmondson EF, Anandasabapathy N, Young HA. Myeloid-Derived Suppressive Cell Expansion Promotes Melanoma Growth and Autoimmunity by Inhibiting CD40/IL27 Regulation in Macrophages. Cancer Res. 2021 Dec 1;81(23):5977-5990.
7: Miyazaki K, Morine Y, Yamada S, Saito Y, Tokuda K, Okikawa S, Yamashita S, Oya T, Ikemoto T, Imura S, Hu H, Morioka H, Tsuneyama K, Shimada M. Stromal tumor-infiltrating lymphocytes level as a prognostic factor for resected intrahepatic cholangiocarcinoma and its prediction by apparent diffusion coefficient. Int J Clin Oncol. 2021 Dec;26(12):2265-2274.
8: Nishida T, Tsuneyama K, Tago Y, Nomura K, Fujimoto M, Nakajima T, Noguchi A, Minamisaka T, Hatta H, Imura J. Effect of Continuous Feeding of Ayu-Narezushi on Lipid Metabolism in a Mouse Model of Metabolic Syndrome. ScientificWorldJournal. 2021 Sep 6;2021:1583154.
9: Toki S, Yoshimaru T, Matsushita Y, Aihara H, Ono M, Tsuneyama K, Sairyo K, Katagiri T. The survival and proliferation of osteosarcoma cells are dependent on the mitochondrial BIG3-PHB2 complex formation. Cancer Sci. 2021 Oct;112(10):4208-4219.
10: Kobayashi T, Ichimura-Shimizu M, Oya T, Ogawa H, Matsumoto M, Morimoto Y, Sumida S, Kakimoto T, Yamashita M, Sutoh M, Toyohara S, Hokao R, Cheng C, Tsuneyama K. Neonatal streptozotocin treatment rapidly causes different subtype of hepatocellular carcinoma without persistent hyperglycemia in 4CS mice fed on a normal diet. Pathol Res Pract. 2021 Sep;225:153559.
11: Chen SY, Tsuneyama K, Yen MH, Lee JT, Chen JL, Huang SM. Hyperbaric oxygen suppressed tumor progression through the improvement of tumor hypoxia and induction of tumor apoptosis in A549-cell-transferred lung cancer. Sci Rep. 2021 Jun 8;11(1):12033.
12: Morimoto Y, Oya T, Ichimura-Shimizu M, Matsumoto M, Ogawa H, Kobayashi T, Sumida S, Kakimoto T, Yamashita M, Cheng C, Tsuneyama K. Applying Probe Electrospray Ionization Mass Spectrometry to Cytological Diagnosis: A Preliminary Study by Using Cultured Lung Cancer Cells. Acta Cytol. 2021;65(5):430-439.
13: Miyazaki K, Morine Y, Imura S, Ikemoto T, Saito Y, Yamada S, Tokuda K, Okikawa S, Yamashita S, Oya T, Tsuneyama K, Shimada M. Preoperative lymphocyte/C-reactive protein ratio and its correlation with CD8+ tumor-infiltrating lymphocytes as a predictor of prognosis after resection of intrahepatic cholangiocarcinoma. Surg Today. 2021 Dec;51(12):1985-1995.
14: Yamashita S, Morine Y, Imura S, Ikemoto T, Saito Y, Takasu C, Yamada S, Tokuda K, Okikawa S, Miyazaki K, Oya T, Tsuneyama K, Shimada M. A new pathological classification of intrahepatic cholangiocarcinoma according to protein expression of SSTR2 and Bcl2. World J Surg Oncol. 2021 May 7;19(1):142.
15: Shimoyama S, Kawata K, Ohta K, Chida T, Suzuki T, Tsuneyama K, Shimoda S, Kurono N, Leung PSC, Gershwin ME, Suda T, Kobayashi Y. Ursodeoxycholic acid impairs liver-infiltrating T-cell chemotaxis through IFN-γ and CX3CL1 production in primary biliary cholangitis. Eur J Immunol. 2021 Jun;51(6):1519-1530.
16: Ichimura-Shimizu M, Omagari K, Yamashita M, Tsuneyama K. Development of a novel mouse model of diet-induced nonalcoholic steatohepatitis-related progressive bridging fibrosis. Biosci Biotechnol Biochem. 2021 Mar 24;85(4):941-947.
17: Matsumoto K, Kikuchi K, Hara A, Tsunashima H, Tsuneyama K, Doi S. Immunohistochemical detection of procalcitonin in fibrolamellar hepatocellular carcinoma. Clin J Gastroenterol. 2021 Jun;14(3):827-830.
18: Tanaka H, Saijo Y, Tomonari T, Tanaka T, Taniguchi T, Yagi S, Okamoto K, Miyamoto H, Sogabe M, Sato Y, Muguruma N, Tsuneyama K, Sata M, Takayama T. An Adult Case of Congenital Extrahepatic Portosystemic Shunt Successfully Treated with Balloon-occluded Retrograde Transvenous Obliteration. Intern Med. 2021 Jun 15;60(12):1839-1845.
19:Influence of age in weeks on the development and progression of nonalcoholic steatohepatitis in a diet-induced Sprague-Dawley rat model. Omagari K, Yamasaki M, Ngo LCT, Koba C, Nagata A, Fukuda A, Suruga K, Ichimurs-Shimizu M, Tsuneyama K. Acta Medica Nagasakiensia 2021 65(1): 7-15.
20:Olive leaf powder prevents nonalcoholic steatohepatitis in Sprague–Dawley rats fed a high-fat and high-cholesterol diet. Omagari K, Koba C, Nagaa A, Ngo LCT, Yamasaki M, Fukuda A, Yuasa M, Suruga K, Inada N, Ichimura-Shimizu M, Tsuneyama K. Clinical Nutrition Open Science. 2021 37: 47-59.
21: Tezuka T, Azuma M, Ogawa H, Kondo M, Uehara H, Aono Y, Hanibuchi M, Nishioka Y. A RAS inhibitor reduces allergic airway remodeling via regulating IL-33-derived type 2 innate lymphoid cells. Exp Lung Res 47(9):451-463, 2021
22: Takasu C, Miyazaki K, Yoshikawa K, Nishi M, Tokunaga T, Kashihara H, Yoshimoto T, Ogawa H, Morine Y, Shimada M. Effect of TU-100 on Peyer's patches in a bacterial translocation rat model. Ann Gastroenterol Surg. 2021 Apr 5;5(5):683-691.
23: Yoshida M, Yuasa M, Ogawa H, Miyamoto N, Kawakami Y, Kondo K, Tangoku A. Can computed tomography differentiate adenocarcinoma in situ from minimally invasive adenocarcinoma? Thorac Cancer. 2021 Apr;12(7):1023-1032.
24: Kondo M, Tezuka T, Ogawa H, Koyama K, Bando H, Azuma M, Nishioka Y. Lysophosphatidic Acid Regulates the Differentiation of Th2 Cells and Its Antagonist Suppresses Allergic Airway Inflammation. Int Arch Allergy Immunol. 2021;182(1):1-13.
25: Ichimura-Shimizu M, Tsuchiyama Y, Morimoto Y, Matsumoto M, Kobayashi T, Sumida S, Kakimoto T, Oya T, Ogawa H, Yamashita M, Matsuda S, Omagari K, Taira S, Tsuneyama K. A novel mouse model of non-alcoholic steatohepatitis suggests that liver fibrosis initiates around lipid-laden macrophages. American Journal of Pathology, Vol. 192 (1), pp.31-42, 2021
26. 清水真祐子.非アルコール性脂肪肝炎および脳機能障害における脂質の挙動. アグリバイオ, Vol.5, No.6, 521-525, 2021.
2020
1: Umezu T, Tsuneyama K, Kanekura K, Hayakawa M, Tanahashi T, Kawano M, Taguchi YH, Toyoda H, Tamori A, Kuroda M, Murakami Y. Comprehensive analysis of liver and blood miRNA in precancerous conditions. Sci Rep. 2020 Dec 10;10(1):21766.
2: Minamikawa T, Ichimura-Shimizu M, Takanari H, Morimoto Y, Shiomi R, Tanioka H, Hase E, Yasui T, Tsuneyama K. Molecular imaging analysis of microvesicular and macrovesicular lipid droplets in non-alcoholic fatty liver disease by Raman microscopy. Sci Rep. 2020 Oct 29;10(1):18548.
3: Kondo M, Izawa-Ishizawa Y, Goda M, Hosooka M, Kagimoto Y, Saito N, Matsuoka R, Zamami Y, Chuma M, Yagi K, Takechi K, Tsuneyama K, Ishizawa K. Preventive Effects of Quercetin against the Onset of Atherosclerosis-Related Acute Aortic Syndromes in Mice. Int J Mol Sci. 2020 Sep 30;21(19):7226.
4: Tsunematsu T, Arakaki R, Kawai H, Ruppert J, Tsuneyama K, Ishimaru N, Earnshaw WC, Pagano M, Kudo Y. APC/C Cdh1 is required for the termination of chromosomal passenger complex activity upon mitotic exit. J Cell Sci. 2020 Sep 15;133(18):jcs251314.
5: Kurano M, Tsukamoto K, Hara M, Tsuneyama K, Nishikawa T, Ikeda H, Yatomi Y. Modulation of sphingosine 1-phosphate by hepatobiliary cholesterol handling. FASEB J. 2020 Nov;34(11):14655-14670.
6: Li M, Wu C, Muhammad JS, Yan D, Tsuneyama K, Hatta H, Cui ZG, Inadera H. Melatonin sensitises shikonin-induced cancer cell death mediated by oxidative stress via inhibition of the SIRT3/SOD2-AKT pathway. Redox Biol. 2020 Sep;36:101632.
7: Akatsu H, Manabe T, Kawade Y, Tanaka H, Kanematsu T, Arakawa K, Masaki Y, Hishida C, Kanesaka T, Ogawa N, Hashizume Y, Tsuneyama K, Ohara H, Maruyama M, Yamamoto T. Iron deposition in autopsied liver specimens from older patients receiving intravenous iron infusion. PLoS One. 2020 Aug 4;15(8):e0237104.
8: Oda S, Miyazaki N, Tsuneyama K, Yokoi T. Exacerbation of gefitinib-induced liver injury by glutathione reduction in mice. J Toxicol Sci. 2020;45(8):493-502.
9: Andoh T, Suzuki K, Konno M, Tsuneyama K, Kuraishi Y. Pharmacological Characterization of a Novel Mouse Model of Cholestatic Pruritus. Biol Pharm Bull. 2020;43(7):1111-1117.
10: Tsutsui A, Harada K, Tsuneyama K, Nguyen Canh H, Ando M, Nakamura S, Mizobuchi K, Baba N, Senoh T, Nagano T, Shibata H, Aoki T, Takaguchi K. Histopathological analysis of autoimmune hepatitis with "acute" presentation: Differentiation from drug-induced liver injury. Hepatol Res. 2020 Sep;50(9):1047-1061.
11: Imanishi M, Yamakawa Y, Fukushima K, Ikuto R, Maegawa A, Izawa-Ishizawa Y, Horinouchi Y, Kondo M, Kishuku M, Goda M, Zamami Y, Takechi K, Chuma M, Ikeda Y, Tsuchiya K, Fujino H, Tsuneyama K, Ishizawa K. Fibroblast-specific ERK5 deficiency changes tumor vasculature and exacerbates tumor progression in a mouse model. Naunyn Schmiedebergs Arch Pharmacol. 2020 Jul;393(7):1239-1250.
12: Takai A, Kikuchi K, Ichimura M, Tsuneyama K, Moritoki Y, Matsumoto K, Tsunashima H, Onda T, Kuniyoshi N, Nariyama T, Ohyatsu S, Kubota J, Nagumo K, Sato S, Hara M, Miyakawa H. Fructo-oligosaccharides ameliorate steatohepatitis, visceral adiposity, and associated chronic inflammation via increased production of short-chain fatty acids in a mouse model of non-alcoholic steatohepatitis. BMC Gastroenterol. 2020 Feb 27;20(1):46.
13: Suwa K, Yamaguchi T, Yoshida K, Murata M, Ichimura M, Tsuneyama K, Seki T, Okazaki K. Smad Phospho-Isoforms for Hepatocellular Carcinoma Risk Assessment in Patients with Nonalcoholic Steatohepatitis. Cancers (Basel). 2020 Jan 24;12(2):286.
14: Omagari K, Suzuta M, Taniguchi A, Kumamoto R, Koyama Y, Fukuda A, Suruga K, Ichimura-Shimizu M, Tsuneyama K. A non-obese, diet-induced animal model of nonalcoholic steatohepatitis in Wistar/ST rats compared to Sprague-Dawley rats Clinical Nutrition Experimental 2020; 30: 1-14
15: Otsuka K, Mitsuhashi A, Goto H, Hanibuchi M, Koyama K, Ogawa H, Ogino H, Saijo A, Kozai H, Yoneda H, Tobiume M, Kishuku M, Ishizawa K, Nishioka Y. Anti- PD-1 antibody combined with chemotherapy suppresses the growth of mesothelioma by reducing myeloid-derived suppressor cells. Lung Cancer. 2020 Aug;146:86-96.
16: Morizumi S, Sato S, Koyama K, Okazaki H, Chen Y, Goto H, Kagawa K, Ogawa H, Nishimura H, Kawano H, Toyoda Y, Uehara H, Nishioka Y. Blockade of Pan- Fibroblast Growth Factor Receptors Mediates Bidirectional Effects in Lung Fibrosis. Am J Respir Cell Mol Biol. 2020 Sep;63(3):317-326.
2019
1. Iida A, Kuranuki A, Yamamoto R, Uchida M, Ohta M, Ichimura M, Tsuneyama K, Masaki T, Seike M, Nakamura T. Analysis of amino acid profiles of blood over time and biomarkers associated with non-alcoholic steatohepatitis in STAM mice. Experimental Animals, 2019: 68, No.4, 417-428.
2. Fukuda A, Sasao M, Asakawa E, Narita S, Hisano M, Suruga K, Ichimura M, Tsuneyama K, Tanaka K, Omagari K. Dietary fat, cholesterol, and cholic acid affect the histopathologic severity of nonalcoholic steatohepatitis in Sprague-Dawley rats. Pathology, Research and Practice 215(11): 152599, 2019.
3. Omagari K, Asakawa E, Sasao M, Narita S, Hisano M, Fukuda A, Suruga K, Ichimura M, Tsuneyama K. Age-related alterations of nonalcoholic steatohepatitis in Sprague-Dawley rats fed a high-fat and high-cholesterol diet. Journal of Nutritional Science and Vitaminology, 65, (4): 349-356, 2019.
3. Omagari K, Asakawa E, Sasao M, Narita S, Hisano M, Fukuda A, Suruga K, Ichimura M, Tsuneyama K. Age-related alterations of nonalcoholic steatohepatitis in Sprague-Dawley rats fed a high-fat and high-cholesterol diet. Journal of Nutritional Science and Vitaminology, 65, (4): 349-356, 2019.
4. Kageyama C, Igawa T, Gion Y, Iwaki N, Tabata T, Tanaka T, Kondo E, Sakai H, Tsuneyama K, Nomoto K, Noguchi H, Yoshino T, Yokota K, Sato Y. Hepatic Campylobacter jejuni infection in patients with Castleman-Kojima disease (idiopathic multicentric Castleman disease with thrombocytopenia, anasarca, fever, reticulin fibrosis, and organomegaly (TAFRO) syndrome). Pathology International, Vol.69, No.10, 572-579, 2019.
5. Terziroli BBP, Mieli-Vergani G, Vergani D, Vierling MJ, Adams D, Alpini G, Banales MJ, Beuers U, Björnsson E, Bowlus C, Carbone M, Chazouillères O, Dalekos G, Gottardi De A, Harada K, Hirschfield G, Invernizzi P, Jones D, Krawitt E, Lanzavecchia A, Lian ZX, Ma X, Manns M, Mavilio D, Quigley ME, Sallusto F, Shimoda S, Strazzabosco M, Swain M, Tanaka A, Trauner M, Tsuneyama K, Zigmond E, Gershwin EM. The challenges of primary biliary cholangitis: What is new and what needs to be done.Journal of Autoimmunity, Vol.105, 2019.
6. Jia R, Oda S, Tsuneyama K, Urano Y, Yokoi T. Establishment of a mouse model of troglitazone-induced liver injury and analysis of its hepatotoxic mechanism. Journal of Applied Toxicology : JAT, 2019.
7. Yang F, Takeuchi T, Tsuneyama K, Yokoi T, Oda S. Experimental Evidence of Liver Injury by BSEP-Inhibiting Drugs With a Bile Salt Supplementation in Rats. Toxicological Sciences, Vol.170, No.1, 95-108, 2019.
8. Takahashi T, Ichikawa H, Morimoto Y, Tsuneyama K, Hijikata T. Inhibition of EP2/EP4 prostanoid receptor-mediated signaling suppresses IGF-1-induced proliferation of pancreatic cancer BxPC-3 cells via upregulating γ-glutamyl cyclotransferase expression.,Biochemical and Biophysical Research Communications, Vol.516, No.2, 388-396, 2019.
9. Takikawa A, Usui I, Fujisaka S, Tsuneyama K, Okabe K, Nakagawa T, Nawaz A, Kado T, Jojima T, Aso Y, Hayakawa Y, Yagi K, Tobe K. Macrophage-specific hypoxia-inducible factor-1α deletion suppresses the development of liver tumors in high-fat diet-fed obese and diabetic mice. Journal of Diabetes Investigation, Vol.10, No.6, 1411-1418, 2019.
10. Kurano M, Tsuneyama K, Morimoto Y, Nishikawa M, Yutaka Yatomi. Apolipoprotein M suppresses the phenotypes of IgA nephropathy in hyper-IgA mice.The FASEB journal, Vol.33, No.4, 5181-5195, 2019.
11. Izawa-Ishizawa Y, Imanishi M, Zamami Y, Hiroki T, Tomoko N, Morishita M, Tsuneyama K, Horinouchi Y, Kihira Y, Takechi K, Ikeda Y, Tsuchiya K, Yoshizumi M, Tamaki T, Ishizawa K. Development of a novel aortic dissection mouse model and evaluation of drug efficacy using in-vivo assays and database analyses. Journal of Hypertension, Vol.37, No.1, 73-83, 2019.
6. Jia R, Oda S, Tsuneyama K, Urano Y, Yokoi T. Establishment of a mouse model of troglitazone-induced liver injury and analysis of its hepatotoxic mechanism. Journal of Applied Toxicology : JAT, 2019.
7. Yang F, Takeuchi T, Tsuneyama K, Yokoi T, Oda S. Experimental Evidence of Liver Injury by BSEP-Inhibiting Drugs With a Bile Salt Supplementation in Rats. Toxicological Sciences, Vol.170, No.1, 95-108, 2019.
8. Takahashi T, Ichikawa H, Morimoto Y, Tsuneyama K, Hijikata T. Inhibition of EP2/EP4 prostanoid receptor-mediated signaling suppresses IGF-1-induced proliferation of pancreatic cancer BxPC-3 cells via upregulating γ-glutamyl cyclotransferase expression.,Biochemical and Biophysical Research Communications, Vol.516, No.2, 388-396, 2019.
9. Takikawa A, Usui I, Fujisaka S, Tsuneyama K, Okabe K, Nakagawa T, Nawaz A, Kado T, Jojima T, Aso Y, Hayakawa Y, Yagi K, Tobe K. Macrophage-specific hypoxia-inducible factor-1α deletion suppresses the development of liver tumors in high-fat diet-fed obese and diabetic mice. Journal of Diabetes Investigation, Vol.10, No.6, 1411-1418, 2019.
10. Kurano M, Tsuneyama K, Morimoto Y, Nishikawa M, Yutaka Yatomi. Apolipoprotein M suppresses the phenotypes of IgA nephropathy in hyper-IgA mice.The FASEB journal, Vol.33, No.4, 5181-5195, 2019.
11. Izawa-Ishizawa Y, Imanishi M, Zamami Y, Hiroki T, Tomoko N, Morishita M, Tsuneyama K, Horinouchi Y, Kihira Y, Takechi K, Ikeda Y, Tsuchiya K, Yoshizumi M, Tamaki T, Ishizawa K. Development of a novel aortic dissection mouse model and evaluation of drug efficacy using in-vivo assays and database analyses. Journal of Hypertension, Vol.37, No.1, 73-83, 2019.
12. Okazaki H, Satou S, Koyama K, Morizumi S, Abe S, Azuma M, Chen Y, Goto H, Aono H, Ogawa H, Kagawa K, Nishimura H, Kawano H, Toyoda Y, Uehara H, Kouji H, Nishioka Y. The novel inhibitor PRI-724 for Wnt/β-catenin/CBP signaling ameliorates bleomycin-induced pulmonary fibrosis in mice. Experimental Lung Research, Vol.45, No.7, 188-199, 2019.
13. Koyama K, Goto H, Morizumi S, Kagawa K, Nishimura H, Satou S, Kawano H, Toyoda Y, Ogawa H, Homma S, Nishioka Y. The Tyrosine Kinase Inhibitor TAS-115 Attenuates Bleomycin-induced Lung Fibrosis in Mice. American Journal of Respiratory Cell and Molecular Biology, Vol.60, No.4, 478-487, 2019.