2016
1. Sasaki E, Iida A, Oda S, Tsuneyama K, Fukami T, Nakajima M, Yokoi T. Pathogenic analysis of carbamazepine-induced liver injury in F344 rats focused on immune-and inflammation-related facters. Exp Toxicol Pathol. 2016 Jan;68(1):27-38.
2. Yamada A, Arakaki R, Saito M, Tsunematsu T, Kudo Y, Ishimaru N. A role of regulatory T cell in the pathogenesis of IBD. World J Gastroenterol. 2016 Feb21;22(7):2195-2205.
3. Kondo T, Tsunematsu T, Yamada A, Arakaki R, Saito M, Otsuka K, Kujiraoka S, Ushio A, Kurosawa M, Kudo Y, Ishimaru N. Acceleration of Tumor Growth due to Dysfunction in M1 Macrophages and Enhanced Angiogenesis in an Animal Model of Autoimmune Disease. Lab Invest. 2016 Jan 25.
4. Obayashi M, Yoshida M, Tsunematsu T, Ogawa I, Sasahira T, Kuniyasu H, Imoto I, Abiko Y, Xu D, Fukunaga S, Tahara H, Kudo Y, Nagao T, Takata T. MicroRNA-203 Suppresses Invasion and Epithelial-mesenchymal Transition Induction via Targeting NUAK1 and SNAI2 in Head and Neck Cancer. Oncotarget. 2016 Jan 22.
5. Saito M, Arakaki R, Yamada A, Tsunematsu T, Kudo Y, Ishimaru N. Molecular Mechanisms of Nickel Allergy. Int J Mol Sci. 2016 Feb 2;17(2).
6. Qi G, Kudo Y, Tang B, Liu T, Jin S, Liu J, Zuo X, Mi S, Shao W, Ma X, Tsunematsu T, Ishimaru N, Zeng S, Tstsuka M, Shimamoto F. PARP6 acts as a tumor suppressor via downregulating Survivin expression in colorectal cancer. Oncotarget. 2016 Feb 25.
7. Kudo Y, Tada H, Fujiwara N, Tada Y, Tsunematsu T, Miyake Y, Ishimaru N. Oral environment and cancer. Gene Environ 2016 Aug 1;38:13.
8. Tsunematsu T, Fujiwara N, Yoshida M, Takayama Y, Kujiraoka S, Qi G, Kitagawa M, Kondo T, Yamada A, Arakaki R, Miyauchi M, Ogawa I, Abiko Y, Nikawa H, Murakami S, Takata T, Ishimaru N, Kudo Y. Human odontogenic epithelial cells derived from epithelial rests of Malasses stem cell properities. Lab Invest 2016 Oct;96(10):1063-75.
9. Izawa T, Arakaki R, Mori H, Tsunematsu T, Kudo Y, Tanaka E, Ishimaru N. The nuclear receptor AhR controls bone homeostasis by regulating osteoclast differentiation via the RANK/c-FOS signaling axis. J Immunol 2016 Dec 15;197(12):4639-4650.
10. Ando T, Kudo Y, Iizuka S, Tsunematsu T, Umehara H, Shrestha M, Matsuo T, Kubo T, Shimose S, Arihiro K, Ogawa I, Ochi M, Takata T. Ameloblastin induces tumor suppressive phenotype and enhances chemosensitivity to doxorubicin via Src-Stat3 inactivation in osteosarcoma. Sci. Rep 2017 Jan 5;7:40187.
11. Qi G, Liu J, Mi S, Tsunematsu T, Jin S, Shao W, Liu T, Ishimaru N, Tang T, Kudo Y. Aurora kinase inhibitors in head and neck cancer. Curr. Top Med.Chem 2018 Jan 12.
12. Yang GX, Sun Y, Tsuneyama K, Zhang W, Leung PS, He XS, et al. Endogenous interleukin-22 protects against inflammatory bowel disease but not autoimmune cholangitis in dominant negative form of transforming growth factor beta receptor type II mice. Clin Exp Immunol. 2016;185(2):154-64.
13. Wakae H, Higashide T, Tsuneyama K, Nakamura T, Takahashi K, Sugiyama K. Immunohistochemical Characterization of the Ectopic Epithelium Devoid of Goblet Cells From a Posttraumatic Iris Cyst Causing Mucogenic Glaucoma. J Glaucoma. 2016;25(3):e291-4.
14. Takikawa A, Usui I, Fujisaka S, Ikutani M, Senda S, Hattori S, et al. Deletion of SIRT1 in myeloid cells impairs glucose metabolism with enhancing inflammatory response to adipose tissue hypoxia. Diabetology International. 2016;7(1):59-68.
15. Takahashi T, Nishida T, Baba H, Hatta H, Imura J, Sutoh M, et al. Histopathological characteristics of glutamine synthetase-positive hepatic tumor lesions in a mouse model of spontaneous metabolic syndrome (TSOD mouse). Mol Clin Oncol. 2016;5(2):267-70.
16. Takikawa A, Mahmood A, Nawaz A, Kado T, Okabe K, Yamamoto S, et al. HIF-1alpha in Myeloid Cells Promotes Adipose Tissue Remodeling Toward Insulin Resistance. Diabetes. 2016;65(12):3649-59.
17. Taira S, Yamaguchi N, Tatsuta Y, Katano H, Tsuneyama K, Kikuchi K. Liver disease risk of xenobiotics due to percutaneous absorption revealed by nano-PALDI imaging mass spectrometry. Int J Recent Sci Res 2016;7(7):12589-92.
18. Oda S, Shirai Y, Akai S, Nakajima A, Tsuneyama K, Yokoi T. Toxicological role of an acyl glucuronide metabolite in diclofenac-induced acute liver injury in mice. J Appl Toxicol. 2016.
19. Nishida T, Tsuneyama K, Fujimoto M, Nomoto K, Hayashi S, Miwa S, et al. Aberrant iron metabolism might have an impact on progression of diseases in Tsumura Suzuki obese diabetes mice, a model of spontaneous metabolic syndrome. Pathol Int. 2016;66(11):622-8.
20. Morimoto S, Ishikawa T, Hyodo K, Yamazaki T, Taira S, Tsuneyama K, et al. Preparation and characterization of newly developed matrix using functional γ‐Fe2O3 nanoparticles for mass spectrometry in small molecules. Surf Interface Anal 2016;48:1127-31.
21. Kawaguchi M, Hara N, Bilim V, Koike H, Suzuki M, Kim TS, et al. A diagnostic marker for superficial urothelial bladder carcinoma: lack of nuclear ATBF1 (ZFHX3) by immunohistochemistry suggests malignant progression. BMC Cancer. 2016;16(1):805.
22. Iwamura A, Watanabe K, Akai S, Nishinosono T, Tsuneyama K, Oda S, et al. Zomepirac Acyl Glucuronide Is Responsible for Zomepirac-Induced Acute Kidney Injury in Mice. Drug Metab Dispos. 2016;44(7):888-96.
23. Bae HR, Leung PS, Tsuneyama K, Valencia JC, Hodge DL, Kim S, et al. Chronic expression of interferon-gamma leads to murine autoimmune cholangitis with a female predominance. Hepatology. 2016;64(4):1189-201.
24. Akai S, Uematsu Y, Tsuneyama K, Oda S, Yokoi T. Kupffer cell-mediated exacerbation of methimazole-induced acute liver injury in rats. J Appl Toxicol. 2016;36(5):702-15.
2015
|
<原著論文> |
|
Takahashi T, Baba H, Hatta H, Ogawa H, Uehara H, Nishida Y, Kataguchi I, Tsuneyama K. Oral administration of α-lipoic acid increases serum levels of ascorbic acid and tocopherol: a pilot hematologyical study. Curr Top Nutraceutical Res. 2015, in press
|
|
Nakajima T, Yagi H, Baba H, Minamisaka T, Miwa S, Hayashi S, Nishida T, Hatta H, Tsuneyama K, Imura J. Complete Resolution of Pseudomalignant Erosion in a Reflux Gastroesophageal Polyp with Proton Pump Inhibitor. Case Rep Pathol. 2015; 657059.
|
|
Tsunashima H, Tsuneyama K, Moritoki Y, Hara M, Kikuchi K. Accumulated myeloid-derived suppressor cells demonstrate distinct phenotypes and functions in two non-alcoholic steatohepatitis mouse models. Hepatobiliary Surg Nutr. 2015 Oct;4(5):313-9.
|
|
Wakae H, Higashide T, Tsuneyama K, Nakamura T, Takahashi K, Sugiyama K. Immunohistochemical Characterization of the Ectopic Epithelium Devoid of Goblet Cells From a Posttraumatic Iris Cyst Causing Mucogenic Glaucoma. J Glaucoma. 2015 Nov 6.
|
|
Yang JB, Wang YH, Yang W, Lu FT, Ma HD, Zhao ZB, Jia YJ, Tang W, Tsuneyama K, Ridgway WM, Gershwin ME, Lian ZX. Successful treatment of murine autoimmune cholangitis by parabiosis: Implications for hematopoietic therapy. J Autoimmun. 2015 Sep 29. pii: S0896-8411(15)30041-X.
|
|
Sasaki E, Iida A, Oda S, Tsuneyama K, Fukami T, Nakajima M, Yokoi T. Pathogenetic analyses of carbamazepine-induced liver injury in F344 rats focused on immune- and inflammation-related factors. Exp Toxicol Pathol. 2016 Jan;68(1):27-38.
|
|
Shinoda K, Taki H, Obayashi K, Ando Y, Watanabe A, Komiya A, Fuse H, Tsuneyama K, Tobe K. Wild-type ATTR amyloidosis of the ureter in a 56-year-old woman with rheumatoid arthritis and Sjögren's syndrome. Int J Clin Exp Pathol. 2015 Jul 1;8(7):8624-7. eCollection 2015.
|
|
Nakajima T, Sugiyama T, Baba H, Hatta H, Nishida T, Miwa S, Hayashi S, Tsuneyama K, Imura J. Bone metastasis in gastrointestinal stromal tumors preferentially occurs in patients with original tumors in sites other than the stomach. Int J Clin Exp Pathol. 2015 May 1;8(5):5955-9. eCollection 2015.
|
|
Cui ZG, Ogawa R, Tsuneyama K, Yan G, Tao L, Shimomura A, Inadera H. Insight into the molecular mechanism of heme oxygenase-1 induction by docosahexaenoic acid in U937 cells. Chem Biol Interact. 2015 Aug 5;238:180-8.
|
|
Hayashi S, Abe Y, Tomita S, Nakanishi Y, Miwa S, Nakajima T, Nomoto K,Tsuneyama K, Fujimori T, Imura J. Primary non-gestational pure choriocarcinoma arising in the ovary: A case report and literature review. Oncol Lett. 2015 May;9(5):2109-2111.
|
|
Lam YF, Tong KK, Kwan KM, Tsuneyama K, Shu SA, Leung PSC, Chu KH. Gastrointestinal Immune Response to the Shrimp Allergen Tropomyosin: Histological and Immunological Analysis in an Animal Model of Shrimp Tropomyosin Hypersensitivity. Int Arch Allergy Immunol., 2015; 167(1):29-40.
|
|
Gao F, Yokoyama S, Fujimoto M, Tsuneyama K, Saiki I, Shimada Y, Hayakawa Y. Comparison of two Kampo medicines in a diet-induced mouse obesity model. Traditional & Kampo med. 2015, in press
|
|
Wada A, Ito A, Iitsuka H, Tsuneyama K, Miyazono T, Murakami J, Shibahara N, Sakurai H, Saiki I, Nakayama T, Yoshie O, Koizumi K, Sugiyama T. Role of chemokine CX3CL1 in progression of multiple myeloma via CX3CR1 in bone microenvironments. Oncol Rep. 2015 Jun;33(6):2935-9.
|
|
Takahashi K, Nagai N, Ogura K, Tsuneyama K, Saiki I, Irimura T, Hayakawa Y. Mammary tissue microenvironment determines T cell-dependent breast cancer-associated inflammation. Cancer Sci. 2015 Jul; 106(7):867-74.
|
|
Takai S, Oda S, Tsuneyama K, Fukami T, Nakajima M, Yokoi T. Establishment of a mouse model for amiodarone-induced liver injury and analyses of its hepatotoxic mechanism. J Appl Toxicol. 2016 jan; 36(1):35-47.
|
|
Iida A, Sasaki E, Yano A, Tsuneyama K, Fukami T, Nakajima M, Yokoi T.Carbamazepine-Induced Liver Injury Requires CYP3A-Mediated Metabolism and Glutathione Depletion in Rats. Drug Metab Dispos. 2015 Jul;43(7):958-68.
|
|
Gao F, Yokoyama S, Fujimoto M, Tsuneyama K, Saiki I, Shimada Y, Hayakawa Y. Effect of keishibukuryogan on genetic and dietary obesity models. Evid Based Complement Alternat Med. 2015;2015:801291.
|
|
Tanaka H, Yang GX, Tomiyama T, Tsuneyama K, Zhang W, Leung PS, Coppel RL, Joh T, Nadler SG, Ansari AA, Bowlus C, Gershwin ME. Immunological potential of cytotoxic T lymphocyte antigen 4 immunoglobulin in murine autoimmune cholangitis. Clin Exp Immunol. 2015 Jun;180(3):371-82.
|
|
Ichimura M, Hatanaka M, Tsuneyama K, Kato S, Omagari K. An SHR/NDmcr-cp Rat Model of Non-alcoholic steatohepatitis with advanced fibrosis induced by a High-fat, High-cholesterol Diet. J Obes Weight Loss There 2015, 5:1
|
|
Ikutani M, Tsuneyama K, Nakae S, Takatsu K. Emerging of IL-33 in inflammation and immune regulation. Inflammation and Regeneration 2015; 35(2), 69-77.
|
|
Ichimura M, Kawase M, Masuzumi M, Sakaki M, Nagata Y, Tanaka K, Suruga K, Tamaru S, Kato S, Tsuneyama K, Omagari K. High-fat and high-cholesterol diet rapidly induces non-alcoholic steatohepatitis with advanced fibrosis in Sprague-Dawley rats. Hepatol Res. 2015 Apr;45(4):458-69.
|
|
Takai S, Higuchi S, Yano A, Tsuneyama K, Fukami T, Nakajima M, Yokoi T.Involvement of immune- and inflammatory-related factors in flucloxacillin-induced liver injury in mice. J Appl Toxicol. 2015 Feb;35(2):142-51
|
|
Tezuka T, Ogawa H, Azuma M, Goto H, Uehara H, Aono Y, Hanibuchi M, Yamaguchi Y, Fujikawa T, Itai A, Nishioka Y.IMD-4690, a novel specific inhibitor for plasminogen activator inhibitor-1, reduces allergic airway remodeling in a mouse model of chronic asthma via regulating angiogenesis and remodeling-related mediators. PLoS One. 2015 Mar 18;10(3):e0121615.
|
|
Takahashi T, Uehara H, Ogawa H, Umemoto H, Bando Y, Izumi K.Inhibition of EP2/EP4 signaling abrogates IGF-1R-mediated cancer cell growth: involvement of protein kinase C-θ activation. Oncotarget. 2015 Mar 10;6(7):4829-44
|
|
Matsui T, Onouchi T, Shiogama K, Mizutani Y, Inada K, Yu F, Hayasaka D, Morita K, Ogawa H, Mahara F, Tsutsumi Y. Coated Glass Slides TACAS Are Applicable to Heat-Assisted Immunostaining and In Situ Hybridization at the Electron Microscopy Level. Acta Histochemica et Cytochemica 48(5) 2015.
|
|
Mitsuhashi A, Goto H, Saijo A, Trung VT, Aono Y, Ogino H, Kuramoto T, Tabata S, Uehara H, Izumi K, Yoshida M, Kobayashi H, Takahashi H, Gotoh M, Kakiuchi S, Hanibuchi M, Yano S, Yokomisa H, Sakiyama S, Nishioka Y. Fibrocyte-like cells mediate acquired resistance to anti-angiogenic therapy with bevacizumab. Nat Commun 6: 8792, 2015.
|
|
Takashima A, Yagi S, Yamaguchi K, Takagi E, Kanbara T, Ogawa H, Ise T, Kusunose K, Tobiume T, Yamada H, Soeki T, Wakatsuki T, Kitagawa T, Sata M, Vegetation of the Coronary Sinus that Concealed the Presence of a Coronary Arteriovenous Fistula in a Patient with Infectious Endocarditis, International Journal of Cardiology, letter to the editor2015.
|
|
<著書> |
|
守時由起、菊池健太郎、常山幸一. 自己免疫性胆管炎：抗ミトコンドリア抗体陰性原発性胆汁性肝硬変免疫症候群（第２版）—その他の免疫疾患を含めて– 別冊日本臨床 新領域別症候群シリーズ No. 34, 369-374. 2015 |
|
佐々塚涼弥、馬場逸人、菊池健太郎、守時由起、常山幸一. 原発性胆汁性肝硬変の免疫病理 肝胆膵 71(5)831−837,2015 |
|
|
.
2014
Uehara H, Takahashi T, Oha M, Ogawa H, Izumi K, Exogenous fatty acid binding protein 4 promotes human prostate cancer cell progression.Int J Cancer. 2014 Dec 1;135(11):2558-68
Ogawa H, Ledford JG, Mukherjee S, Aono Y, Nishioka Y, Lee JJ, Izumi K, Hollingsworth JW. Surfactant protein D attenuates sub-epithelial fibrosis in allergic airways disease through TGF-β. Respir Res. 2014 Nov 29;15(1):143
Sato S, Hanibuchi M, Fukuya A, Yabuki Y, Bando H, Yoshijima T, Goto H, Ogawa H, Nishioka Y..Idiopathic pleuroparenchymal fibroelastosis is characterized by an elevated serum level of surfactant protein-D, but Not Krebs von den Lungen-6. Lung. 2014 Oct;192(5):711-7.
Aono Y, Kishi M, Yokota Y, Azuma M, Kinoshita K, Takezaki A, Sato S, Kawano H, Kishi J, Goto H, Uehara H, Izumi K, Nishioka Y. Role of PDGF/PDGFR axis in the trafficking of circulating fibrocytes in pulmonary fibrosis. Am J Respir Cell Mol Biol. 2014. 51(6):793-801,.
Tajiri K, Tsuneyama K, Kawai K, Atarashi Y, Minemura M, Sawada S, Tsukada K, Imura J, Sugiyama T. A case of progressing focal nodular hyperplasia and its molecular expression pattern. Clin J Gastroenterol. 2014 Jun;7(3):271-7.
2013
Takahashi T, Uehara H, Izumi K. Inhibitory effect of soluble EP2 receptor on ovarian tumor growth in nude mice and utility of TMPRSS4 as a combinatorial molecular target. Int J Oncol. 2013 Aug;43(2):416-24.
Uehara H, Takahashi T, Izumi K. Induction of retinol-binding protein 4 and placenta-specific 8 expression in human prostate cancer cells remaining in bone following osteolytic tumor growth inhibition by osteoprotegerin. Int J Oncol. 2013 Aug;43(2):365-74.
Honjo A, Ogawa H, Azuma M, Tezuka T, Sone S, Biragyn A, Nishioka Y. Targeted reduction of CCR4+ cells is sufficient to suppress allergic inflammation. Respir Investig. 51(4):241-249, 2013.
Kinoshita K, Aono Y, Azuma M, Kishi J, Takezaki A, Kishi M, Makino H, Okazaki H, Uehara H, Izumi K, Sone S, Nishioka Y. Antifibrotic effects of focal adhesion klinase inhibitor in bleomycin-induced pulmonary fibrosis in mice. Am J Respir Cell Mol Biol. 49(4):536-543, 2013.
Yamada T, Takeuchi S, Fujita N, Nakamura A, Wang W, Li Q, Oda M, Mitsudomi T, Yatabe Y, Sekido Y, Yoshida J, Higashiyama M, Noguchi M, Uehara H, Nishioka Y, Sone S, Yano S. Akt kinase -interacting protein1, a novel therapeutic target for lung cancer with EGFR-activating and gatekeeper mutations. Oncogene. 32(37):4427-4435, 2013.
Mitsuhashi A, Goto H, Kuramoto T, Tabata S, Yukishige S, Abe S, Hanibuchi M, Kakiuchi S, Saijo A, Aono Y, Uehara H, Yano S, Ledford JG, Sone S, Nishioka Y. Surfactant protein A suppresses lung cancer progression by regulating the polarization of tumor-associated macrophages. Am J Pathol. 182(5):1843-1853, 2013.
Sato S, Hanibuchi M, Kuramoto T, Yamamori N, Goto H, Ogawa H, Mitsuhashi A, Van TT, Kakiuchi S, Akiyama SI, Nishioka Y, Sone S. Macrophage stimulating protein promotes liver metastases of small cell lung cancer cells by affecting the organ microenvironment. Clin Exp Metastasis. 30(3):333-344, 2013.
Makino H, Aono Y, Azuma M, Kishi M, Yokota Y, Kinoshita K, Takezaki A, Kishi J, Kawano H, Ogawa H, Uehara H, Izumi K, Sone S, Nishioka Y. Antifibrotic effects of CXCR4 antagonist in bleomycin -induced pulmonary fibrosis in mice. J Med Invest. 60(1-2):127-137, 2013.
2012
Bando Y, Takahashi T, Uehara H, Kagegi T, Nagahiro S, Izumi K: Autopsy case of amebic granulomatous meningoencephalitis caused by Balamuthia mandrillaris in Japan, Pathol Int 2012, 62:418-423
Fukawa T, Ono M, Matsuo T, Uehara H, Miki T, Nakamura Y, Kanayama HO, Katagiri T: DDX31 Regulates the p53-HDM2 Pathway and rRNA Gene Transcription through Its Interaction with NPM1 in Renal Cell Carcinomas, Cancer research 2012, 72:5867-5877
Kuramoto T, Goto H, Mitsuhashi A, Tabata S, Ogawa H, Uehara H, Saijo A, Kakiuchi S, Maekawa Y, Yasutomo K, Hanibuchi M, Akiyama SI, Sone S, Nishioka Y: Dll4-Fc, an Inhibitor of Dll4-Notch Signaling, Suppresses Liver Metastasis of Small Cell Lung Cancer Cells through the Downregulation of the NF-kappaB Activity, Molecular cancer therapeutics 2012,
Nakagawa M, Bando Y, Nagao T, Takai C, Ohnishi T, Honda J, Moriya T, Izumi K, Takahashi M, Tangoku A, Sasa M: Among triple-negative breast cancers, HER2(0) breast cancer shows a strong tendency to be basal-like compared with HER2(1+) breast cancer: preliminary results, Breast Cancer 2012, 19:54-59
Ogawa H, Azuma M, Uehara H, Takahashi T, Nishioka Y, Sone S, Izumi K: Nerve growth factor derived from bronchial epithelium after chronic mite antigen exposure contributes to airway hyperresponsiveness by inducing hyperinnervation, and is inhibited by in vivo siRNA, Clin Exp Allergy 2012, 42:460-470
Takasu C, Shimada M, Kurita N, Iwata T, Sato H, Nishioka M, Morimoto S, Yoshikawa K, Miyatani T, Kashihara H, Utsunomiya T, Uehara H: Survivin expression can predict the effect of chemoradiotherapy for advanced lower rectal cancer, International journal of clinical oncology / Japan Society of Clinical Oncology 2012,
Yu DY, Zhao QL, Furuta M, Todoriki S, Izumi K, Yamakage K, Matsumoto K, Nomura T, Kondo T: Molecular mechanisms of apoptosis induction by 2-dodecylcyclobutanone, a radiolytic product of palmitic acid, in human lymphoma U937 cells, Apoptosis 2012, 17:636-645