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研究業績 2022年

• Yamanashi Y, Takada T, Tanaka Y, Ogata Y, Toyoda Y, Ito SM, Kitani M, Oshida N, Okada K, Shoda J, Suzuki H. Hepatic Niemann-Pick C1-Like 1 exacerbates non-alcoholic fatty liver disease by re-absorbing specific biliary oxysterols. Biomed Pharmacother. 2022 156:113877. [open access]
• Kariya Y, Honma M, Tokuda K, Konagaya A, Suzuki H. Utility of constraints reflecting system stability on analyses for biological models. PLoS Comput Biol. 2022 18(9):e1010441. [open access]
• Yamaguchi R, Yamamoto T, Okamoto K, Tatsuno K, Ikeda M, Tanaka T, Wakabayashi Y, Sato T, Okugawa S, Moriya K, Suzuki H. Prospective audit and feedback implementation by a multidisciplinary antimicrobial stewardship team shortens the time to de-escalation of anti-MRSA agents. PLoS One 2022 17(7):e0271812. [abstract]
• Tomabechi R, Kishimoto H, Sato T, Saito N, Kiyomiya K, Takada T, Higuchi K, Shirasaka Y, Inoue K. SLC46A3 is a lysosomal proton-coupled steroid conjugate and bile acid transporter involved in transport of active catabolites of T-DM1. PNAS Nexus 2022 in press. [abstract] [プレスリリース]
• Tojima Y, Taguchi A, Mori M, Nara K, Miyamoto Y, Tanikawa M, Sone K, Tsuruga T, Yamamoto T, Oda K, Suzuki H, Osuga Y. Effect of primary prophylaxis with pegfilgrastim in endometrial cancer patients treated with doxorubicin and cisplatin. Taiwan J Obstet Gynecol. 2022 61(2):265-269. [abstract]
• Takata T, Sasaki H, Yamano H, Honma M, Shikano M. Study on Horizon Scanning with a Focus on the Development of AI-Based Medical Products: Citation Network Analysis. Ther Innov Regul Sci . 2022 56(2):263-275. [abstract]
• Fujii E, Takata T, Yamano H, Honma M, Shimokawa M, Sasaki H, Shikano M. Study on Horizon Scanning by Citation Network Analysis and Text Mining: A Focus on Drug Development Related to T Cell Immune Response. Ther Innov Regul Sci . 2022 56(2):230-243. [abstract]
• Toyoda Y, Kawamura Y, Nakayama A, Morimoto K, Shimizu S, Tanahashi Y, Tamura T, Kondo T, Kato Y, Ichida K, Suzuki H, Shinomiya N, Kobayashi Y, Takada T, Matsuo H. OAT10/SLC22A13 acts as a renal urate re-absorber: clinico-genetic and functional analyses with pharmacological impacts. Front Pharmacol. 2022 13:842717. [open acccess]
• Toyoda Y, Takada T, Saito H, Hirata H, Ota-Kontani A, Tsuchiya Y, Suzuki H. Identification of Inhibitory Activities of Dietary Flavonoids against URAT1, a Renal Urate Re-Absorber: In Vitro Screening and Fractional Approach Focused on Rooibos Leaves. Nutrients 2022 14(3):575. [open acccess]
• Miyata H, Toyoda Y, Takada T, Hiragi T, Kubota Y, Shigesawa R, Koyama R, Ikegaya Y, Suzuki H. Identification of an exporter that regulates vitamin C supply from blood to the brain. iScience 2022 25(1):103642. [open access] [プレスリリース] (PDF)
  Featured in NHK WORLD JAPAN 『Vitamin C: The Key to Health and Longevity』
• Chang SJ, Toyoda Y, Kawamura Y, Nakamura T, Nakatochi M, Nakayama A, Liao WT, Shimizu S, Takada T, Takeuchi K, Wakai K, Shi Y, Shinomiya N, Chen CJ, Li C, Okada Y, Ichida K, Matsuo H. A meta-analysis of genome-wide association studies using Japanese and Taiwanese has revealed novel loci associated with gout susceptibility. Hum Cell 2022 35(2):767-770. [open acccess]
• Nakayama A, Kawamura Y, Toyoda Y, Shimizu S, Kawaguchi M, Aoki Y, Takeuchi K, Okada R, Kubo Y, Imakiire T, Iwasawa S, Nakashima H, Tsunoda M, Ito K, Kumagai H, Takada T, Ichida K, Shinomiya N, Matsuo H. Genetic-epidemiological analysis of hypouricemia from 4,993 Japanese on nonfunctional variants of URAT1/SLC22A12 gene. Rheumatology 2022 61(3):1276-1281. [abstract]
• Yamaguchi R, Kani H, Yamamoto T, Tanaka T, Suzuki H. Development of a decision flowchart to identify the patients need high-dose vancomycin in early phase of treatment. J Pharm Health Care Sci. 2022 8(1):3. [abstract]