感染病態研究グループ(119研究室)
- 研究室紹介
- 119研究室は感染症内科の設立された研究室です。臨床と研究の両面から日々研究に取り組んでいます。
特に細菌感染症に関連した臨床および基礎研究を行い、新たな診断・治療法の開発を目指しています。
- 研究内容
- これまでに、自然免疫機構として代表的な受容体であるToll-like Receptorの細胞内情報伝達や細胞内動態の解析、C. difficileの構成タンパクと自然免疫の制御の関連性、肺炎クラミジアによる動脈硬化発症の分子機序、Tリンパ球の自然免疫と獲得免疫の関連性、キノロン薬の免疫調節機構、HIVのRNAによる免疫応答性の解析、HIV薬がもたらす副作用の分子機構の解析などを行ってきました。
現在は、大腸菌や芽胞菌などによる細菌感染症に主に焦点を当て研究を行っています。大腸菌では、これまで十分に検討されていない発症および重症化因子の研究を行いました。芽胞菌は、B. cereusおよびC. difficileの分子および臨床疫学や病原因子の調査・解析を行っています。クロストリジウム菌血症の研究にも最近では取り組んでいます。
- 連絡先
- 日々の診療の中から生じる疑問を大切にし、その謎を解き明かそうと日々研究を行っています。感染症診療の新しい未来を作りたいという思いを持った方を歓迎しています。
私たちの研究室に興味のある方は、
奥川(okugawa-tky(アットマーク)umin.ac.jp)まで連絡ください。
- 発表論文(抜粋)
- 2022年から2024年まで
- 1. Ito H, Okamoto K, Ariyoshi T, Yamamoto S, Yamashita M, Kanno Y, Ikeda
M, Okugawa S, Moriya K. Neisseria meningitidis serogroup W135 in a traveler
visiting Japan from Argentina, 2019. J Infect Chemother. 2022;28:1180-1181.
2. Jin C, Wakimoto Y, Ikeda M, Ohama Y, Ri M, Yamashita H, Ohtani A, Yamashita
M, Shinohara T, Jubishi D, Kanno Y, Okamoto K, Higurashi Y, Harada S, Okugawa
S, Seto Y, Moriya K. Human abdominal abscess caused by Necropsobacter rosorum
and tips for its identification: A case report. J Infect Chemother. 2022;28:833-835.
3. Jubishi D, Okamoto K, Hamada K, Ishii T, Hashimoto H, Shinohara T, Yamashita
M, Wakimoto Y, Otani A, Hisasue N, Ikeda M, Harada S, Okugawa S, Moriya
K, Yanagimoto S. The association between adverse reactions and immune response
against SARS-CoV-2 spike protein after vaccination with BNT162b2 among
healthcare workers in a single healthcare system: a prospective observational
cohort study. Hum Vaccin Immunother. 2022;18:2048559.
4. Kitaura S, Okamoto K, Wakabayashi Y, Okada Y, Okazaki A, Ikeda M, Okugawa
S, Fujimoto F, Bujo C, Minatsuki S, Tsushima K, Chikamatsu K, Mitarai S,
Moriya K. A Cold-Blooded Tiptoer: Nonresolving Cellulitis in an Immunocompromised
Patient. Open Forum Infect Dis. 2022;9:ofac074.
5. Morita Y, Kurano M, Jubishi D, Ikeda M, Okamoto K, Tanaka M, Harada
S, Okugawa S, Moriya K, Yatomi Y. Urine sediment findings were milder in
patients with COVID-19-associated renal injuries than in those with non-COVID-19-associated
renal injuries. Int J Infect Dis. 2022;117:302-311.
6. Yamaguchi R, Yamamoto T, Okamoto K, Tatsuno K, Ikeda M, Tanaka T, Wakabayashi
Y, Sato T, Okugawa S, Moriya K, Suzuki H. Prospective audit and feedback
implementation by a multidisciplinary antimicrobial stewardship team shortens
the time to de-escalation of anti-MRSA agents. PLoS One. 2022;17:e0271812.
7. Yamamoto S, Ikeda M, Ohama Y, Sunouchi T, Hoshino Y, Ito H, Yamashita
M, Kanno Y, Okamoto K, Yamagoe S, Miyazaki Y, Okugawa S, Fujishiro J, Moriya
K. Aureobasidium melanigenum catheter-related bloodstream infection: a
case report. BMC Infect Dis. 2022;22:335.
8. 21. Yamashita M, Ikeda M, Kato I, Ohama Y, Ando M, Ikemura M, Jubishi
D, Kanno Y, Okamoto K, Umeyama T, Nakamura S, Miyazaki Y, Okugawa S, Moriya
K. Protothecosis in the mucosa of the pharynx mimicking pharyngeal cancer
in an immunocompetent individual: a case report. Ann Clin Microbiol Antimicrob.
2022;21:5.
9. 1. Kitaura S, Tobiume M, Kawahara M, Satoh M, Kato H, Nakayama N, Nakajima
N, Komeno T, Furuta Y, Suzuki T, Moriya K, Saijo M, Ebihara H, Takayama-Ito
M. Evaluation of a novel severe combined immunodeficiency mouse model for
antiviral drug evaluation against Chandipura virus infection. Antiviral
Res. 2023;213:105582.
10. 2. Hashiba T, Sugahara M, Ota Y, Kaseda K, Kashiwagi Y, Nakamura M,
Shinohara T, Ikeda M, Okugawa S, Sugimoto K, Sasaki K, Hamasaki Y, Yamada
D, Kume H, Moriya K, Nangaku M. Paralytic Ileus during Treatment of Pulmonary
and Renal Tuberculosis in a Non-Human Immunodeficiency Virus Patient: An
Unusual Presentation of Tuberculosis-immune Reconstitution Inflammatory
Syndrome. Intern Med. 2023;62:2559-2564.
11. Ikeda M, Kobayashi T, Okugawa S, Fujimoto F, Okada Y, Tatsuno K, Higurashi
Y, Tsutsumi T, Moriya K. Comparison of phylogenetic and virulence factors
between Escherichia coli isolated from biliary tract infections and uropathogenic
Escherichia coli. Heliyon. 2023;9:e21748.
12. Ikeda M, Okugawa S, Kashiwabara K, Moritoyo T, Kanno Y, Jubishi D,
Hashimoto H, Okamoto K, Tsushima K, Uchida Y, Mitsumura T, Igari H, Tsutsumi
T, Araoka H, Yatera K, Yamamoto Y, Nakamura Y, Otani A, Yamashita M, Wakimoto
Y, Shinohara T, Adachi-Katayama M, Oyabu T, Kanematsu A, Harada S, Takeshita
Y, Nakano Y, Miyazaki Y, Sakao S, Saito M, Ogura S, Yamasaki K, Kawasuji
H, Hataji O, Inoue JI, Seto Y, Moriya K. Multicenter, single-blind, randomized
controlled study of the efficacy and safety of favipiravir and nafamostat
mesilate in patients with COVID-19 pneumonia. Int J Infect Dis. 2023;128:355-363.
13. Ishii T, Hamada K, Jubishi D, Hashimoto H, Okamoto K, Hisasue N, Sunohara
M, Saito M, Shinohara T, Yamashita M, Wakimoto Y, Otani A, Ikeda M, Harada
S, Okugawa S, Moriya K, Yanagimoto S. Waning cellular immune responses
and predictive factors in maintaining cellular immunity against SARS-CoV-2
six months after BNT162b2 mRNA vaccination. Sci Rep. 2023;13:9607.
14. Okugawa S, Ikeda M, Kashiwabara K, Moritoyo T, Kohsaka T, Shimizu T,
Hagiya H, Hasegawa K, Otsuka F, Miwa A, Kisimoto N, Mizoguchi A, Imamura
A, Ikeuchi K, Tsutsumi T, Jubishi D, Hashimoto H, Okamoto K, Harada S,
Inoue JI, Seto Y, Moriya K. Antiviral effect and safety of nafamostat mesilate
in patients with mild early-onset COVID-19: An exploratory multicentre
randomized controlled clinical trial. Int J Antimicrob Agents. 2023;62:106922.
15. Oyama S, Adachi-Katayama M, Okamoto K, Jin C, Yamamura K, Saito Y,
Kanematsu A, Otani A, Wakimoto Y, Oyabu T, Jubishi D, Hashimoto H, Harada
S, Okugawa S, Moriya K. Preseptal cellulitis with Streptococcus pyogenes
complicated by streptococcal toxic shock syndrome: A case report and review
of literature. J Infect Chemother. 2023;29:783-786.
16. Hiraike Y, Saito K, Oguchi M, Wada T, Toda G, Tsutsumi S, Bando K,
Sagawa J, Nagano G, Ohno H, Kubota N, Kubota T, Aburatani H, Kadowaki T,
Waki H, Yanagimoto S, Yamauchi T. NFIA in adipocytes reciprocally regulates
mitochondrial and inflammatory gene program to improve glucose homeostasis.
Proc Natl Acad Sci U S A. 2023;120:e2308750120.
17. Abe M, Ohsato A, Fujihara Y, Hoshi K, Yanagimoto S. A Comparative Study
of Periodontal Health Status between International and Domestic University
Students in Japan. Int J Environ Res Public Health. 2023;20.
18. Adachi-Katayama M, Hashimoto H, Hagiwara S, Yamashita M, Mihara Y,
Kanematsu A, Otani A, Wakimoto Y, Oyabu T, Jubishi D, Okamoto K, Harada
S, Akamatsu N, Hoshino Y, Okugawa S, Hasegawa K, Moriya K. Pulmonary Nocardiosis
Due to Nocardia exalbida Infection Following Living-donor Liver Transplantation.
Intern Med. 2024.
19. Arashiro T, Miwa M, Nakagawa H, Takamatsu J, Oba K, Fujimi S, Kikuchi
H, Iwasawa T, Kanbe F, Oyama K, Kanai M, Ogata Y, Asakura T, Asami T, Mizuno
K, Sugita M, Jinta T, Nishida Y, Kato H, Atagi K, Higaki T, Nakano Y, Tsutsumi
T, Doi K, Okugawa S, Ueda A, Nakamura A, Yoshida T, Shimada-Sammori K,
Shimizu K, Fujita Y, Okochi Y, Tochitani K, Nakanishi A, Rinka H, Taniyama
D, Yamaguchi A, Uchikura T, Matsunaga M, Aono H, Hamaguchi M, Motoda K,
Nakayama S, Yamamoto K, Oka H, Tanaka K, Inoue T, Kobayashi M, Fujitani
S, Tsukahara M, Takeda S, Stucky A, Suzuki T, Smith C, Hibberd M, Ariyoshi
K, Fujino Y, Arima Y, Takeda S, Hashimoto S, Suzuki M. COVID-19 vaccine
effectiveness against severe COVID-19 requiring oxygen therapy, invasive
mechanical ventilation, and death in Japan: A multicenter case-control
study (MOTIVATE study). Vaccine. 2024;42:677-688.
20. Kanno Y, Okamoto K, Shinohara T, Kinoshita O, Hatano M, Ikeda M, Harada
S, Okugawa S, Moriya K, Ono M, Tsutsumi T. Pre-Transplant Seroprevalence,
Associated Factors, and Post-Transplant Incidence of Toxoplasma gondii
Infection Among Heart Transplant Recipients in Japan. Transplant Proc.
2024;56:148-152.
21. Kawase K, Okamoto K, Harada S, Nomura Y, Shimada S, Komae H, Kuroda
R, Ideyama M, Soma K, Mizoguchi M, Higurashi Y, Ukai K, Adachi-Katayama
M, Miwa T, Wakimoto Y, Oyabu T, Jubishi D, Hashimoto H, Okugawa S, Ono
M, Doi K, Ushiku T, Tsutsumi T. A case of hypervirulent K1-ST23 Klebsiella
pneumoniae endocarditis and papillary muscle rupture secondary to multiple
site abscesses. J Infect Chemother. 2024;30:154-158.
22. Miwa T, Okamoto K, Ikeuchi K, Yamamoto S, Okugawa S, Ichida A, Akamatsu
N, Hasegawa K, Tsutsumi T. The Role of Frequent Screening or Diagnostic
Testing of Serum Cryptococcal Antigen in Liver Transplant Recipients: A
Descriptive Epidemiology. Open Forum Infect Dis. 2024;11:ofae255.
23. Okutani A, Okugawa S, Fujimoto F, Ikeda M, Tsutsumi T, Moriya K, Maeda
K. Draft genome sequence including the capsule operon of a Bacillus cereus
strain isolated from a patient with bacteremia in Japan. Microbiol Resour
Announc. 2024;13:e0076623.
24. Tateishi S, Hamada K, Emoto N, Abe K, Abe K, Kawasaki Y, Sunohara M,
Moriya K, Katayama H, Tsutsumi T, Murakami Y, Suzuki Y, Yotsuyanagi H,
Yanagimoto S. Facility wastewater monitoring as an effective tool for pandemic
infection control: An experience in COVID-19 pandemic with long-term monitoring.
J Infect Chemother. 2024.
25. Okubo S, Mano T, Sudo A, Goto R, Yano S, Hara M, Ishiura H, Satake
W, Yanagimoto S, Ogata H, Toda T. Anti-neurofascin 155 Antibody-positive
Neuropathy in a Human Immunodeficiency Virus-infected Patient. Intern Med.
2024;63:565-569.
26. Nakagawa S, Ono N, Hakamata Y, Ishii T, Saito A, Yanagimoto S, Kanaya
S. Quantitative evaluation model of variable diagnosis for chest X-ray
images using deep learning. PLOS Digit Health. 2024;3:e0000460.
27. Lee CL, Yamada T, Liu WJ, Hara K, Yanagimoto S, Hiraike Y. Interaction
between type 2 diabetes polygenic risk and physical activity on cardiovascular
outcomes. Eur J Prev Cardiol. 2024;31:1277-1285.
28. Kitaura S, Okamoto K. The effect of infectious diseases on lung transplantation
in Japan. J Thorac Dis. 2024;16:1632-1644.
- 2020年から2021年
- 1. Ikeda M, Wakabayashi Y, Okamoto K, Yanagimoto S, Okugawa S, Moriya K.
Changing trends in lipid profile and biomarkers of renal function and bone
metabolism before and after switching from tenofovir disoproxil fumarate
to tenofovir alafenamide: a prospective observational study. AIDS Res Ther.
2021;18:30.
2. Ikeda M, Kobayashi T, Fujimoto F, Okada Y, Higurashi Y, Tatsuno K, Okugawa
S, Moriya K. The prevalence of the iutA and ibeA genes in Escherichia coli
isolates from severe and non-severe patients with bacteremic acute biliary
tract infection is significantly different. Gut Pathog. 2021;13:32.
3. Kobayashi T, Nakajima K, Oshima Y, Ikeda M, Kitaura S, Ikeuchi K, Okamoto
K, Okada Y, Ohama Y, Higurashi Y, Okugawa S, Moriya K. First Reported Human
Case of Spondylodiscitis by Staphylococcus condimenti: A Case Report and
Literature Review. Intern Med. 2021;60:635-637.
4. Yamamoto S, Ikeda M, Kanno Y, Okamoto K, Okugawa S, Moriya K. Microbiological
analysis of infectious lymphocele: Case series and literature review. J
Infect Chemother. 2021;27:172-178.
5. Osawa I, Okamoto K, Ikeda M, Otani A, Wakimoto Y, Yamashita M, Shinohara
T, Kanno Y, Jubishi D, Kurano M, Harada S, Okugawa S, Yatomi Y, Moriya
K. Dynamic changes in fibrinogen and D-dimer levels in COVID-19 patients
on nafamostat mesylate. J Thromb Thrombolysis. 2021;51:649-656.
6. Shimura T, Kurano M, Kanno Y, Ikeda M, Okamoto K, Jubishi D, Harada
S, Okugawa S, Moriya K, Yatomi Y. Clot waveform of APTT has abnormal patterns
in subjects with COVID-19. Sci Rep. 2021;11:5190.
7. Shinohara T, Okamoto K, Koyano S, Otani A, Yamashita M, Wakimoto Y,
Jubishi D, Hashimoto H, Ikeda M, Harada S, Okugawa S, Moriya K. Plesiomonas
shigelloides Septic Shock Following Ingestion of Dojo Nabe (Loach Hotpot).
Open Forum Infect Dis. 2021;8:ofab401.
8. Ikeuchi K, Okamoto K, Inoue N, Okugawa S, Moriya K. Chronic Disseminated
Gonococcal Infection in a Japanese Man with Novel C5 Gene Mutation. J Clin
Immunol. 2021;41:691-693.
9. Ishihara Y, Okamoto K, Shimosaka H, Ono Y, Kanno Y, Ikeda M, Harada
S, Kurano M, Okugawa S, Moriya K, Yatomi Y. Prevalence and clinical characteristics
of patients with biologically false-positive reactions with serological
syphilis testing in contemporary practice: 10-year experience at a tertiary
academic hospital. Sex Transm Infect. 2021;97:397-401.
10. Okada Y, Yagihara Y, Wakabayashi Y, Igawa G, Saito R, Higurashi Y,
Ikeda M, Tatsuno K, Okugawa S, Moriya K. Epidemiology and virulence-associated
genes of Clostridioides difficile isolates and factors associated with
toxin EIA results at a university hospital in
Japan. Access Microbiololgy. 2020;2.
11. Kitaura S, Okamoto K, Wakabayashi Y, Okada Y, Okazaki A, Ikeda M, Hakuta
R, Nakai Y, Okugawa S, Koike K, Moriya K. Vibrio fluvialis Liver Abscess
and Bacteremia in a Sashimi Lover: A Case Report and Review of the Literature.
Open Forum Infect Dis. 2020;7:ofaa212.
12. Usui Y, Ayibieke A, Kamiichi Y, Okugawa S, Moriya K, Tohda S, Saito
R. Impact of deoxycholate on Clostridioides difficile growth, toxin production,
and sporulation. Heliyon. 2020;6:e03717.
13. Kitaura S, Wakabayashi Y, Okazaki A, Okada Y, Okamoto K, Ikeda M, Okugawa
S, Moriya K. The First Case Report of Acute Symptomatic HEV Genotype 4
Infection in an HIV-positive Patient in Japan. Intern Med. 2020;59:1655-1658.
14. Okamoto K, Asano S, Yamamoto T, Toyono T, Yamaguchi R, Okada Y, Okugawa
S, Suzuki H, Moriya K, Aihara M. Poor penetration of cefcapene into aqueous
humor after oral administration of cefcapene pivoxil to patients undergoing
cataract surgery. J Infect Chemother. 2020;26:312-315.
15. Okada Y, Okugawa S, Ikeda M, Kobayashi T, Saito R, Higurashi Y, Moriya
K. Genetic diversity and epidemiology of accessory gene regulator loci
in Clostridioides difficile. Access Microbiol. 2020;2:acmi000134.
16. Shinohara T, Otani A, Yamashita M, Wakimoto Y, Jubishi D, Okamoto K,
Kanno Y, Ikeda M, Ishigaki K, Nakai Y, Harada S, Okugawa S, Koike K, Moriya
K. Acute Pancreatitis During COVID-19 Pneumonia. Pancreas. 2020;49:e106-e108.
17. Mizoguchi M, Harada S, Okamoto K, Higurashi Y, Ikeda M, Moriya K. Comparative
performance and cycle threshold values of 10 nucleic acid amplification
tests for SARS-CoV-2 on clinical samples. PLoS One. 2021;16:e0252757.
18. Mitani A, Hamada K, Yoshikawa N, Morita Y, Horie T, Inoue Y, Saito
M, Ishii T, Sunohara M, Takahashi R, Emoto N, Nishimoto N, Murano Y, Okazaki
S, Tateishi S, Yao A, Shimura T, Kurano M, Yatomi Y, Yanagimoto S. Epidemiological
study using IgM and IgG antibody titers against SARS-CoV-2 in The University
of Tokyo, Japan (UT-CATS). J Infect Chemother. 2021;27:1342-1349.
19. Abe M, Mitani A, Yao A, Zhang CD, Hoshi K, Yanagimoto S. Close Association
between Awareness of Teeth-Alignment Disorder and Systemic Disorders in
Late Adolescence. Healthcare (Basel). 2021;9.
20. Abe M, Mitani A, Yao A, Zong L, Hoshi K, Yanagimoto S. Awareness of
Malocclusion Is Closely Associated with Allergic Rhinitis, Asthma, and
Arrhythmia in Late Adolescents. Healthcare (Basel). 2020;8.
21. Abe M, Mitani A, Hoshi K, Yanagimoto S. Large Gender Gap in Oral Hygiene
Behavior and Its Impact on Gingival Health in Late Adolescence. Int J Environ
Res Public Health.2020;17.
22. Nguyen TB, Sakata-Yanagimoto M, Fujisawa M, Nuhat ST, Miyoshi H, Nannya
Y, Hashimoto K, Fukumoto K, Bernard OA, Kiyoki Y, Ishitsuka K, Momose H,
Sukegawa S, Shinagawa A, Suyama T, Sato Y, Nishikii H, Obara N, Kusakabe
M, Yanagimoto S, Ogawa S, Ohshima K, Chiba S. Dasatinib Is an Effective
Treatment for Angioimmunoblastic T-cell Lymphoma. Cancer Res. 2020;80:1875-1884.
23. Abe M, Mitani A, Yao A, Takeshima H, Zong L, Hoshi K, Yanagimoto S.
Close Associations of Gum Bleeding with Systemic Diseases in Late Adolescence.
Int J Environ Res Public Health. 2020;17.
- 2018年から2020年まで
- 1. Yokoyama A, Kage H, Ohama Y, Sato T, Miyashita N, Noguchi S, Okugawa
S, Yamauchi Y, Moriya K, Nagase T. Mycobacterium heckeshornense lung infection
diagnosed by matrix-assisted laser desorption ionization-time of flight
mass spectrometry (MALDI-TOF MS). J Infect Chemother. 2018;24:763-765.
2. Morita K, Honda A, Koya J, Toyama K, Ikeda M, Misawa Y, Okugawa S, Nakamura
F, Moriya K, Kurokawa M. Three cases of Candida fermentati fungemia following
hematopoietic stem cell transplantation. J Infect Chemother. 2018;24:576-578.
3. Sato S, Aoyama T, Uejima Y, Furuichi M, Suganuma E, Takano T, Ikeda
M, Mizoguchi M, Okugawa S, Moriya K, Niimi H, Kitajima I, Kawashima H,
Kawano Y. Pyogenic liver abscess due to hypervirulent Klebsiella pneumoniae
in a 14-year-old boy. J Infect Chemother. 2018.
4. Yamamoto S, Ikeda M, Fujimoto F, Okamoto K, Wakabayashi Y, Sato T, Tatsuno
K, Kaburaki T, Yoshida S, Okugawa S, Koike K, Moriya K. Bilateral Candida
endophthalmitis accompanying Candida lusitaniae bloodstream infection:
A case report. J Infect Chemother. 2018;24:147-149.
5. Ikeda M, Mizoguchi M, Oshida Y, Tatsuno K, Saito R, Okazaki M, Okugawa
S, Moriya K. Clinical and microbiological characteristics and occurrence
of Klebsiella pneumoniae infection in Japan. Int J Gen Med. 2018;11:293-299.
6. Ohsato A, Abe M, Ohkubo K, Yoshimasu H, Zong L, Hoshi K, Takato T, Yanagimoto
S, Yamamoto K. A Comparative Study of Oral Health Status between International
and Japanese University Student Patients in Japan. Healthcare (Basel).
2018;6.
7. Nishijima H, Suzuki S, Kondo K, Yamasoba T, Yanagimoto S. Environmental
factors associated with allergic rhinitis symptoms in Japanese university
students: A cross-sectional study. Auris Nasus Larynx. 2018;45:1006-1013.
8. Yamamoto S, Okamoto K, Okugawa S, Moriya K. Fusobacterium necrophorum
septic pelvic thrombophlebitis after intrauterine device insertion. Int
J Gynaecol Obstet. 2019;145:122-123.
9. Wakabayashi Y, Jubishi D, Okamoto K, Ikeda M, Tatsuno K, Mizoguchi M,
Sato T, Okugawa S, Moriya K. A rare case of a prostatic abscess, bacteremia
and chronic granulomatous disease associated with Klebsiella pneumoniae.
J Infect Chemother.2019.
10. Sato S, Aoyama T, Uejima Y, Furuichi M, Suganuma E, Takano T, Ikeda
M, Mizoguchi M, Okugawa S, Moriya K, Niimi H, Kitajima I, Kawashima H,
Kawano Y. Pyogenic liver abscess due to hypervirulent Klebsiella pneumoniae
in a 14-year-old boy. J Infect Chemother. 2019;25:137-140.
11. Miyashita H, Okamoto K, Kobayashi T, Wakabayashi Y, Kitaura S, Ikeuchi
K, Ishigaki K, Nakai Y, Okugawa S, Koike K, Moriya K. Bacterial peritonitis
in a patient with malignant ascites caused by pancreatic carcinoma: Case
report and review of literature. J Infect Chemother. 2019.
12. Okamoto K, Asano S, Yamamoto T, Toyono T, Yamaguchi R, Okada Y, Okugawa
S, Suzuki H, Moriya K, Aihara M. Poor penetration of cefcapene into aqueous
humor after oral administration of cefcapene pivoxil to patients undergoing
cataract surgery. J Infect Chemother. 2019.
13. Tatsuno K, Ikeda M, Wakabayashi Y, Yanagimoto S, Okugawa S, Moriya
K. Clinical Features of Bloodstream Infections Associated with Peripheral
Versus Central Venous Catheters. Infect Dis Ther. 2019;8:343-352.
14. Saito A, Hakamata Y, Yamada Y, Sunohara M, Tarui M, Murano Y, Mitani
A, Tanaka K, Nagase T, Yanagimoto S. Pleural thickening on screening chest
X-rays: a single institutional study. Respir Res. 2019;20:138.