Sep 28, 2023

Discovery of GR-KLF15 pathway regulating triglyceride synthesis in the liver.

Previously, we found that a transcriptional complex involving the transcription factor KLF15 plays an important role in suppressing the expression of the transcription factor SREBP-1, which acts as a switch to regulate the expression of genes throughout the triglyceride synthesis pathway, during fasting (Cell Rep. 2016). In the current study, we have elucidated the important role of the glycocorticoid receptor (GR) for mechanisms regulating KLF15 expression upstream of this KLF15. Learn more.

　

Feb 7, 2023

New screening method for MCI (mild cognitive impairment).

We have developed a scale, named the visual dependency index of postural stability (VPS), to scan for mild cognitive impairment (MCI). The scale uses a Nintendo Wii balance board to assess balance capability and vestibular function. Learn more.

　

May 13, 2022

Development of a new educational program for diabetes patients using DX.

In collaboration with Habitus Care/JMDC Inc., we have developed a new program to enable diabetes educational hospitalizations to be done at home by DX. Learn more.

　

May 9, 2022

Clinical trial on dietary therapy Using an AI smartphone app launched in collaboration with Oishii Kenko Co.

We will start a clinical trial to analyze and improve eating behavior and measure the effect of suppressing elevated blood glucose levels by providing “Oishii Kenko”, a smartphone application equipped with AI menu and nutrition management functions, to type 2 diabetes patients in collaboration with Oishii Kenko Co. Learn more.

　

November 17, 2021

Elucidation of the mechanism how insulin transcriptionally controls the flow between fat, glucose and protein, in the 100th anniversary year of insulin discovery.

We discovered the mechanism how insulin transcriptionally controls the flow of macronutrients. Learn more.

　

April 9, 2020

Co-production of “One-Week Safe Menu for Diabetic Patients”

“One-week safe menu for diabetic patients supervised by University of Tsukuba Hospital” jointly developed with “Delicious Health” Co., Ltd. will be available for free on the website from April 9, 2020. Learn more.

　

April 24, 2018

Superior medical economy of fingertip HbA1c checks in the pharmacy – Early detection of diabetes in the Specimen Measurement Office is highly effective and leads to cost reduction.

We analyzed the cost-effectiveness of fingertip HbA1c checks in the specimen measurement offices opened at pharmacies, and clarified for the first time the high medical and economic value of the specimen measurement offices in the early detection and treatment of diabetes. Learn more.

　

June 08, 2017

Number of laboratories at pharmacies nationwide exceeds 1,500

Since it was established in 2014 as a new national program, pharmacies and drugstores across the country have been opening specimen measurement offices, and the number reached 1,513 as of the end of May 2017. Learn more.

　

April 27, 2017

Smile Lab, Habitus Care, the University of Tokyo, and the University of Tsukuba are collaborating on a scientific evidence-based industry-academic collaboration for joint development of healthcare programs

Square Enix Group’s Smile Lab Co., Ltd., Habitus Care Inc., Professor Yoshiyuki Arai of the Graduate School of Pharmaceutical Sciences, the University of Tokyo, and Associate Professor Naoya Yahagi of Nutrigenomics Research Group, Faculty of Medicine, University of Tsukuba, have agreed to jointly develop the scientific evidence-based “health care programs” and advance the study of data-based health care services. Learn more.

　

August 19, 2016

Discovery of ON/OFF mechanism of fat synthesis according to dietary conditions – A step forward to the treatment of hyperlipidemia

For the first time, we have elucidated the mechanism by which triglyceride synthesis in the liver is turned on and off according to dietary conditions. Learn more.

　

March 31, 2014

Preventing the onset and aggravation of diabetes – A place for simple testing to detect early diabetes has got legally approved and more accessible

On March 31, 2014, the Ministry of Health, Labour and Welfare (MHLW) promulgated a revision of the notification related to the Clinical Laboratory Technician Act, clarifying the legal position of self-blood testing at pharmacies, in response to the results of the Revolution of Access to Diabetes Diagnosis (RADD) Project. Learn more.

　

August 13, 2013

Discovery of a system for detecting the shortage of glycogen in the liver – A step forward in the treatment of obesity by elucidating its relationship with fat burning

We discovered that there is a mechanism in the liver that senses the decrease in glycogen levels, and this mechanism is responsible for the fasting process, switching our energy source from liver glycogen to triglycerides in adipose tissue. Learn more.

October 12, 2011

Over-The-Counter “Fingertip HbA1c Test” found diabetes in 13% of visitors at Pharmacy

Since October 2010, the Revolution of Access to Diabetes Diagnosis (RADD) Project has been the first innovative trial in Japan to screen diabetes with fingertip HbA1c testing at nine pharmacies and drugstores in Adachi-ku, Tokyo. In the first year since the project began, 538 people (not including people being treated for diabetes) performed fingertip HbA1c measurements, and about 13% of people were revealed to be strongly suspicious of diabetes (HbA1c (NGSP) was 6.5 or higher). Learn more.