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Mechanism 

早期予測

Early Prediction

根本治療

Therapeutics


Profiles


Ichiro Kawahata

Ichiro Kawahata
Doctor of Science and Doctor of Pharmaceutical Science, Associate Professor at Fukushima Medical University
AMED Translational Research Project (Seeds B) Research Representative, JST-MASP Research Representative
　After graduating from the Graduate School of Bioscience and Biotechnology at Tokyo Institute of Technology in 2009, he became an assistant professor at the Graduate School of Pharmaceutical Sciences at Tohoku University in 2010, a specially appointed associate professor in 2020, and has been running the Department of Advanced Brain Drug Discovery at the same university since 2021. He has also been a member of the Faculty of Medicine at Fukushima Medical University since 2024. He was a member of the Tohoku University Young Leader Overseas Dispatch Program (Florey Institute of the University of Melbourne) in 2022 and 2023. Aiming to elucidate the pathogenesis of Parkinson's disease and develop therapeutic drugs, we are working on research to elucidate the mechanism of selective loss of tyrosine hydroxylase, which is essential for dopamine biosynthesis, in dopamine neurons, and to explore new drug targets by elucidating the pathogenesis of α-synucleinopathy, which is dependent on fatty acid binding protein. We are also working to develop treatment applications and screening techniques for patients with Lewy body diseases, including Parkinson's disease, dementia with Lewy bodies, and multiple system atrophy, as well as Alzheimer's disease, based on our understanding of the pathology of these diseases. We aim to achieve a society with brain health and longevity through these achievements in the areas of diagnosis, prevention, and treatment.
Researchmap: https://researchmap.jp/ichiro_kawahata

Awards, committee memberships, etc.: 36th Japanese Pharmacological Society Award for Young Scientists, 46th Japanese Neuroscience Society Award for Young Scientists, 17th Intelligent Cosmos Award for Young Scientists, APSB MS Outstanding Research Award, JSNP Excellent Presentation Award for AsCNP, Academic Councilor of the Japanese Pharmacological Society, Representative of the Next Generation of the Japanese Pharmacological Society (2024-), Young Organizer of the Pharmacological Society of the Pharmaceutical Society of Japan, etc.

Kohji Fukunaga

Kohji Fukunaga
Doctor of Medicine, Professor Emeritus at Tohoku University
AMED Fusion Brain Research Representative, AMED Translational Research (Seeds B) Research Collaboration, JST-MASP Research Collaboration
　After graduating from the Graduate School of Pharmaceutical Sciences at Kumamoto University in 1980, he was employed as a research assistant at the university's Faculty of Medicine, and in 1985 he received his Doctor of Medicine. From 1988, he continued his studies as a postdoctoral fellow at the HHMI at Vanderbilt University in the United States, and in 1990 he became a lecturer at the Faculty of Medicine at Kumamoto University, and in 1993 he became an assistant professor there. he was appointed Professor at the Graduate School of Pharmaceutical Sciences, Tohoku University. He discovered CaM kinase II (CaMKII) in 1982, and has since made many research achievements, including the role of CaMKII in abnormal spine formation in mental retardation, the functional regulation of dopamine D2 receptors by fatty acid binding protein (FABP), and the elucidation of the pathogenic mechanism of Lewy body disease by FABP. In addition to neuroscience, he also contributed to drug discovery science, including the development of seeds for the treatment of Alzheimer's disease and Lewy body disease targeting CaMKII and FABP. In academic activities, he served as the editor-in-chief and director of the English-language journal JPS for a long time, and made a great contribution to Japanese pharmacology. He is working on the commercialization of his research results in the drug discovery business.
Researchmap: https://researchmap.jp/Kohji_Fukunaga

Awards, committee memberships, etc.: 8th Japanese Pharmacological Society Award for Young Scientists, Kumamoto Medical Association Award for Young Scientists, Editor-in-Chief of the Journal of Pharmacological Sciences, Director of the Japanese Pharmacological Society, Director of the Japanese Society for Cerebral Circulation and Metabolism, Director of the Japanese Society for Brain Science, Director of the Japanese Society for Nitric Oxide Research, President of the 47th Annual Meeting of the Japanese Society for Brain Science, etc.

Atsuhi Takeda

Atsushi Takeda
Doctor of Medicine, Director of the National Sendai Nishi-Taga Hospital
AMED Fusion Brain Research, AMED Translational Research (Seeds B), JST-MASP Research Collaboration
　Director of the National Hospital Organization Sendai-Nishitaga Hospital, and a specialist in neurology. Graduated from Tohoku University School of Medicine in 1985, and obtained a doctorate in medicine from the same university's graduate school in 1992. After that, he worked as a lecturer and associate professor at Tohoku University Hospital, and has held his current position since 2014. He is particularly active in the treatment and research of Parkinson's disease and related disorders, and has attracted worldwide attention for his research showing that severe olfactory dysfunction can predict the onset of dementia in Parkinson's disease. He was also involved in the revision of the Parkinson's disease treatment guidelines, and served as vice-chairman of the committee for the 2018 edition. In addition to the treatment of neurodegenerative diseases and muscle diseases, Sendai Nishitaga Hospital also provides rehabilitation incorporating the latest treatment methods. In order to improve the quality of life of patients, the hospital places importance on collaboration with health and welfare organizations, and is committed to providing comprehensive medical services.
Researchmap: https://researchmap.jp/Atsushi_Takeda

Awards, committee memberships, etc.: Tohoku Cerebrovascular Disease Conference Nakamura Takashi Award, Inoue Foundation for Science Promotion Research Encouragement Award, Japanese Society of Neurology Narabayashi Award, Japanese Society of Neurology Councilor, Japanese Society of Neurology Peer Review Committee Member, Parkinson's Disease and Movement Disorder Congress Executive Committee Member, Japanese Society of Parkinson's Disease and Movement Disorder Journal Editorial Committee Member, etc.

Staffs
Nagisa Sawada,　Mihoko Nemoto,　Nozomi Takahashi,　Sao Kawahata

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This homepage is operated with the aim of gaining the understanding of the general public by widely communicating the results of research and therapeutic development from the Grant-in-Aid for Scientific Research (KAKENHI), the Japan Agency for Medical Research and Development (AMED) Translational Research Strategic Promotion Program, and the Japan Science and Technology Agency (JST) University-Launched New Industry Creation Fund Program Startup Ecosystem Co-Creation Program (MASP).
CNS Drug Innovation, Main Laboratory
Institute of Biomedical Sciences,
Fukushima Medical University
1 Hikarigaoka, Fukushima 960-1295, Japan
https://researchmap.jp/ichiro_kawahata
+81-24-547-1968 (direct) E-Mail