臨床幹細胞生物学講座について講座業績

発表論文

1. Investigation of cartilage modification for controlling immune reaction against xenogeneic cartilage.
   Uto S, Mori D, Sakamoto T, Nisizawa S, Yano F, Ohba S, Saito T, Takato T, Hoshi K, Hikita A. Regen Ther. 2026 Apr 15;32:101113. doi: 10.1016/j.reth.2026.101113. eCollection 2026 Jun. PMID: 42027401
2. Role of WIF-1 in regulating chondrocyte dedifferentiation and matrix production through WNT pathway.
   Chu YY, Asawa Y, Tsuji N, Sakamoto T, Liu D, Hoshi K, Hikita A. Regen Ther. 2026 Mar 3;31:101083. doi: 10.1016/j.reth.2026.101083. eCollection 2026 Mar. PMID: 41809618
3. Hepatocyte growth factor in biosheets promotes autonomous regeneration of cutaneous tissue after transplantation onto a full-thickness skin defect.
   Suzuki K, Komura H, Konno R, Kawashima Y, Watanabe E, Sato H, Matsumoto K, Inaki R, Kanazawa S, Asawa Y, Hikita A, Hoshi K, Fujishiro J, Komura M. Mater Today Bio. 2026 Feb 25;37:102969. doi: 10.1016/j.mtbio.2026.102969. eCollection 2026 Apr. PMID: 41809384
4. Identification of mesenchymal stem cell populations with high osteogenic potential using difference in cell division rate.
   Watanabe M, Asawa Y, Riu D, Sakamoto T, Hoshi K, Hikita A. Regen Ther. 2025 Feb 4;28:498-508. doi: 10.1016/j.reth.2025.01.020. eCollection 2025 Mar. PMID: 39991510
5. Small extracellular vesicles derived from auricular chondrocytes promote secretion of interleukin 10 in bone marrow M1-like macrophages.
   Kobatake T, Miyamoto Y, Fujihara Y, Saijo H, Hoshi K, Hikita A. Regen Ther. 2025 Jan 24;28:421-430. doi: 10.1016/j.reth.2025.01.009. eCollection 2025 Mar. PMID: 39925964
6. Establishment of a mouse organ culture model of fetal cleft lip for the evaluation of adipose-derived stem cell therapy.
   Fukutome A, Sakamoto T, Asawa Y, Riu D, Kawakami H, Hoshi K, Hikita A. Regen Ther. 2024 Nov 30;28:41-50. doi: 10.1016/j.reth.2024.11.012. eCollection 2025 Mar. PMID: 39687332
7. Advancements in chondrocyte 3-dimensional embedded culture: Implications for tissue engineering and regenerative medicine.
   Chu YY, Hikita A, Asawa Y, Hoshi K. Biomed J. 2025 Apr;48(2):100786. doi: 10.1016/j.bj.2024.100786. Epub 2024 Sep 3. PMID: 39236979
8. A Comparative Study of Macrophages Derived from Bone Marrow and Spleen.
   Sawada M, Kubota K, Hoshi K, Hikita A. 2024 Jun;19(1):91-103.
9. Inhibition of cysteine protease disturbs the topological relationship between bone resorption and formation in vitro.
   Ono S, Tsuji N, Sakamoto T, Oguchi S, Nakamura T, Hoshi K, Hikita A. J Bone Miner Metab. 2024 Mar;42(2):166-184. doi: 10.1007/s00774-023-01489-w. Epub 2024 Feb 20. PMID: 38376670
10. miR-92a-3p-inspired shRNA exhibits pro-chondrogenic and chondrocyte protective effects in osteoarthritis treatment through targeting SMAD6/7.
    Zheng C, Hoshi K, Hikita A. J Bone Miner Metab. 2024 Jan;42(1):1-16. doi: 10.1007/s00774-023-01474-3. Epub 2023 Dec 6. PMID: 38055109
11. Lipoaspirate stored at a constant low temperature by electric control suppresses intracellular metabolism and maintains high cell viability.
    Inaki R, Sato Y, Nakamura D, Aikawa Y, Takato T, Hoshi K, Hikita A. Regen Ther. 2023 Nov 21;24:662-669. doi: 10.1016/j.reth.2023.11.005. eCollection 2023 Dec. PMID: 38028938
12. Effect of the Correction of Bilateral Differences in Masseter Muscle Functional Pressure on the Mandible of Growing Rats.
    Mizuno S, Matsunaga S, Kasahara N, Kasahara M, Shimoo Y, Abe S, Nakano T, Ishimoto T, Hikita A, Nojima K, Nishii Y. J Funct Biomater. 2023 Aug 21;14(8):435. doi: 10.3390/jfb14080435. PMID: 37623679
13. Subcutaneously Transplanted Fresh Cartilage in Allogeneic and Xenogeneic Immunocompetent Mouse.
    Uto S, Hikita A, Mori D, Sakamoto T, Yano F, Ohba S, Saito T, Takato T, Hoshi K. Tissue Eng Part A. 2023 Oct;29(19-20):541-556. doi: 10.1089/ten.TEA.2023.0052. PMID: 37548556
14. Involvement of Impaired Angiogenesis and Myelosuppression in Antiresorptive-agent Related Osteonecrosis of the Jaw Mouse Model.
    Igarashi H, Nishizawa S, Miyamoto T, Hikita A, Hoshi K. Tokai J Exp Clin Med. 2023 Apr 20;48(1):22-31. PMID: 36999390
15. Spatiotemporal Analysis of Osteoblast Morphology and Wnt Signal-Induced Osteoblast Reactivation during Bone Modeling in Vitro.
    Tsuji N, Sakamoto T, Hoshi K, Hikita A. JBMR Plus. 2022 Oct 21;6(11):e10689. doi: 10.1002/jbm4.10689. eCollection 2022 Nov. PMID: 36398107
16. Quantitative analyses of matrices, osteoblasts, and osteoclasts during bone remodeling using an in vitro system.
    Oguchi S, Sakamoto T, Hoshi K, Hikita A. J Bone Miner Metab. 2023 Jan;41(1):3-16. doi: 10.1007/s00774-022-01381-z. Epub 2022 Nov 7. PMID: 36344637
17. Hematopoietic-Mesenchymal Signals Regulate the Properties of Mesenchymal Stem Cells.
    Kanazawa S, Okada H, Riu D, Mabuchi Y, Akazawa C, Iwata J, Hoshi K, Hikita A. Int J Mol Sci. 2022 Jul 26;23(15):8238. doi: 10.3390/ijms23158238. PMID: 35897814