A Case Report of Ductus Arteriosus Aneurysm in an Adult with Non-specific Inflammatory Response

Takeshi Murakami1	Takashi Miura1	Hisao Sano2
Taku Inoue1	Mizuki Sumi3	Ichiro Matsumaru1
Seiji Matsukuma4	Kazuyoshi Tanigawa5	Kiyoyuki Eishi1

（Department of Cardiovascular Surgery1, and Department of Pathology2, Nagasaki University Hospital, Nagasaki, Japan, Department of Cardiovascular Surgery, Hakujuji Hospital3, Fukuoka, Japan, Department of Cardiovascular Surgery, National Hospital Organization, Nagasaki Medical Center4, Nagasaki, Japan, and Department of Cardiovascular Surgery, St. Mariana University School of Medicine, Yokohama Seibu Hospital5, Yokohama, Japan）

A 24-year-old man was admitted to another hospital due to fever and chest and back pain. Enhanced chest computed tomography showed an aneurysm between the distal aortic arch and left pulmonary artery. The patient was transferred to our hospital for surgery. Because of suspicion of an infectious ductus arteriosus aneurysm, antibiotic therapy was started. Urgent graft replacement of the descending aorta was performed on the third day due to the enlargement of the aneurysm. All blood cultures including the preoperative examination, and the aneurysmal culture were negative. The histopathological study showed non-specific inflammatory response with plasma cell, T lymphocyte, and B lymphocyte infiltrations. There was no evidence of infection. Eventually we diagnosed this patient as having a ductus arteriosus aneurysm with non-specific inflammation. The antibiotic therapy was terminated on postoperative day 10, and the postoperative course was uneventful.

 

Jpn. J. Cardiovasc. Surg. 50:61-64（2021）

Keywords：adult ductus arteriosus aneurysm;suspicion of infectious aortic aneurysm;non-specific inflammatory response