A Case Report of Aortic Valve Replacement for a Patient with von Willebrand Disease

Kazue Nakashima	Yukihiro Yoshimura	Shuji Toyama
Yoshiyuki Maekawa	adanori Minagawa	Mitsuaki Sadahiro

（Department of Cardiovascular, Thoracic and Pediatric Surgery, School of Medicine, Yamagata University, Yamagata, Japan）

We report a 30-year-old patient with von Willebrand disease who received AVR under cardio-pulmonary bypass. AR was diagnosed at the age of 13, and von Willebrand disease was revealed after cardiac catheterization because of a bleeding episode. His von Willebrand factor（vWF）activity was significantly low, 43% of normal. Infusion of vWF concentrates（Confact F●R）was administered before surgery. AVR was safely performed and no bleeding complications occurred during the perioperative period. Blood transfusion was unnecessary, vWF infusion was considered to be very useful.

 

Jpn. J. Cardiovasc. Surg. 44:292-295（2015）

Keywords：Von Willebrand’s disease;aortic valve replacement;vWF infusion