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Collagen Gel Droplet-Embedded Culture Drug Sensitivity Test（CD-DST） for a Leiomyosarcoma Originating in the Inferior Vena Cava
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（Department of Surgery II, Kochi Medical School, Nangoku, Japan）
| Nobuo Kondo |
Masaki Yamamoto |
Hideaki Nishimori |
| Takashi Fukutomi |
Seiichiro Wariishi |
Kazuki Kihara |
| Miwa Tashiro |
Kazumasa Orihashi |
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The collagen gel droplet-embedded culture drug sensitivity test（CD-DST）identifies effective anticancer drug using resected tumor specimen, enabling tailor-made chemotherapy for a rare tumor. We report a case of the patient with leiomyosarcoma originating in the inferior vena cava, to which CD-DST was applied. This application has not been previously reported to the best of our knowledge. A 61-year-old woman consulted a nearby hospital because of abdominal pain. Computed tomography revealed an inferior vena cava tumor. The tumor was resected with the inferior vena cava, which was reconstructed with a 16mm ePTFE graft. The tumor was diagnosed as leiomyosarcoma histopathologically. CDDP, VP-16, ADR, and VDS were CD-DST showed the tumor to be sensitive. Her postoperative course has been good without recurrence of tumor for 6 months, and the results of CD-DST may be helpful for chemotherapy strategy in case of recurrence.
Jpn. J. Cardiovasc. Surg. 42:124-127（2013）
Keywords：leiomyosarcoma in the inferior Vena cava, CD-DST, reconstruction of inferior Vena cava, anticancer drug sensitive test
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