A Case of Immunoglobulin G4-Related Cardiac Tumor around the Coronary Artery
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(Department of Cardiovascular Surgery, and Department of Surgery*, National Hospital Organization Tokyo Medical Center, Tokyo, Japan)
Masahiko Okamoto |
Masashi Nagumo |
Tetsuya Goto |
Akihiro Yoshitake |
Takahisa Miki |
Koji Osumi* |
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Immunoglobulin G4(IgG4)-related disease can occur in various organs, most of which comprise glandular or ductal tissue. We report a case of IgG4-related disease which occurred in a cardiovascular lesion. A 69-year-old man was found to have a tumorous lesion around the coronary artery. Open chest biopsy showed the diffuse lymphoplasmacytic infiltration, occasional eosinophils and numerous IgG4-positive plasma cells within the lesions. The serum concentration of IgG4 in the postoperative period was 1,080mg/dl(reference range, <135). We diagnosed IgG4-related periarteritis manifesting as a tumor around the coronary artery. This case suggests that IgG4-related disease can occur around the coronary artery and manifest as a periarterial mass lesion.
Jpn. J. Cardiovasc. Surg. 39:230-233(2010)
Keywords:IgG4-related disease, cardiac tumor, periarterial mass lesion, coronary artery
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