Assessment of Pulse Wave Velocity as a Marker of Postoperative Cardiovascular Risk in CABG Patients

(Department of Cardiovascular Surgery, Tachikawa Medical Center, Nagaoka, Japan)

Tsutomu Sugimoto Kazuo Yamamoto Koji Shimada
Masatake Katsu Yasunori Iida Takehito Mishima
Fuyuki Asami Shinpei Yoshii Shigetaka Kasuya
Pulse wave velocity is widely used as an index of arterial stiffness. The aim of this study is to assess the usefulness of pulse wave velocity as a risk factor in patients who underwent coronary artery bypass grafting. Arterial stiffness was measured by brachial-ankle pulse wave velocity (baPWV) and the ratio of the patientfs baPWV to the age-matched normal value was calculated in 42 CABG patients. Age and male/female ratios were 66.7 years and 33/9, respectively. baPWV (1,820.7}459.8cm/s) was higher in CABG patients than that in age-matched normal value. Preoperatively, the baPWV ratio in the group with the history of cerebrovascular disease was significantly higher than that in the group who had no cerebrovascular disease (pƒ0.05). @In contrast, the baPWV ratio did not correlate to the severity of other cardiovascular diseases. There was one (2.4%) in-hospital death and 23 incidences of postoperative complication in 16 patients. The baPWV ratio in the group with postoperative complications was significantly higher than that in the group with no complications (1.38}0.33 vs.1.16}0.22; pƒ0.05). In this study, baPWV in CABG patients was higher compared with that in the age-matched general population, indicating the existence of atherosclerotic vascular changes. The elevated bePWV is also a risk factor of postoperative complications in patients who have undergone CABG.
@Jpn. J. Cardiovasc. Surg. 36: 117-120 (2007)