Aortic Root Replacement with a Freestyle Porcine Valve in a Young Woman with Systemic Lupus Erythematosus and Antiphospholipid Antibodies

(Department of Cardiovascular Surgery, Kawachi General Hospital, Higashiosaka, Japan)

Harumasa Yasuda Nobuo Sakagoshi
Aortic root replacement with a Freestyle™ stentless porcine valve (Medtronic Inc.) was performed on a 32-year-old woman for aortic root aneurysm. The patient had been given a diagnosis of systemic lupus erythematosus and had been maintained on steroid therapy for 15 years. Lupus anticoagulant was present and the anticardiolipin antibody titer was abnormal as follows: IgG, 2.0IU/ml (normal1.0IU/ml). For the patient requiring aortic root reconstruction, many options are available. The use of a biological valved conduit should be considered for patients in whom anticoagulation is not desirable. The Freestyle™ stentless porcine valve offers an acceptable alternative to mechanical prostheses, especially for cases with contraindication for anticoagulant therapy, associated with antiphospholipid antibodies.
@Jpn. J. Cardiovasc. Surg. 34: 194-197 (2005)