| Coronary Artery Bypass Graft
in a Patient Who Had Increased Aspartate Aminotransferase (AST)
and Alanine Aminotransferase (ALT) Levels after Treatment with
Heparin |
(Division of Cardiovascular Surgery, Mitsui Memorial
Hospital, Tokyo, Japan)
| Sachito Fukuda |
Sumio Miura |
Ikutaro Kigawa |
| Takeshi Miyairi |
|
|
|
Cardiac surgery using heparin was
performed in a patient in whom AST and ALT had been increased
due to continuous drip infusion of heparin sodium. Here, we report
postoperative changes in AST and ALT in the patient. The patient
was a 59-year-old man with a past medical history of left internal
carotid artery constriction and right cerebral infarction. Because
of his previous medical history, continuous drip infusion of
heparin was initiated upon discontinuation of preoperative antithrombotic
agents. AST and ALT increased, but returned to normal levels
when heparin was discontinued. Heparin was used to avoid aggravation
of the symptoms, and bypass of 3 branches was performed with
pulsation. Postoperative respiration and circulatory dynamics
were stable, and the courses of AST and ALT were similar to those
after general surgery, without abnormally high levels. Although
the cause of heparin-induced increases in AST and ALT is unknown,
the absence of postoperative increases may have been due to transient
use at a high dose and neutralization by protamine.
Jpn. J. Cardiovasc. Surg.34: 137-139 (2005) |
|
