| Effects of Modified Ultrafiltration
in Pediatric Cardiac Surgery |
(Cardiac Surgery, Kumamoto City Hospital, Kumamoto,
Japan)
| Kazuyuki Miyamoto |
Kunihiro Yonenaga |
Touitsu Hirayama |
| Ichiro Ideta |
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Modified ultrafiltration (MUF) for
cardiopulmonary bypass (CPB) in children decreases total body
water and improves left heart function. We investigated the effects
of MUF in pediatric open-heart surgery. Eighty-six patients less
than 15kg who underwent radical cardiac operation were divided
into four groups according to whether they received transfusion
during the operation or not, and whether MUF was performed after
completion of CPB or not. MUF group showed significantly higher
hematocrit levels 20 min after the end of CPB compared with non-MUF
group in both transfused group and non-transfused group. Then,
MUF group showed a significantly higher serum protein level than
non-MUF group. In MUF groups, the systolic blood pressure elevated
without the elevation of the left atrial pressure. We calculated
PaO2/FiO2 as an index of postoperative
lung function. The postoperative PaO2/FiO2 of MUF group was significantly
higher than that of non-MUF group in transfused group. MUF significantly
decreased homologous blood transfusion during the operation.
MUF after CPB elevated hematocrit level and serum protein level,
and improved cardiac function without volume load. Since MUF
reduced the need for homologous blood transfusion. MUF is a useful
means for pediatric cardiac surgery.
Jpn. J. Cardiovasc. Surg. 30: 290-294 (2001) |
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