Accuracy of Measurement of Cardiac Output and Circulating Blood Volume Levels by Pulse Dye Densitometry, and Postoperative Management of the Open Heart Surgery

(Department of Surgery II, Ehime University School of Medicine, Ehime, Japan)

Yoshihiro Hamada Tetsuya Yamamoto Tatsuhiro Nakata
Yasuaki Kashu Yuji Watanabe Hiroyuki Kikkawa
Kanji Kawachi
Using the DDG-2001 pulse dye densitometer, cardiac output (CO) and circulating blood volume (BV) were determined before and after the operation, and its accuracy and the significance of postoperative management were studied. Referring to 14 cases undergoing open heart surgery, CO and BV were determined using the DDG-2001 before application of the cardiopulmonary bypass and immediately, 4h and 12h after the operation. The level of CO was compared with that determined by the thermodilution method, and the level of BV with that calculated from hemoglobin levels determined before and after the cardiopulmonary bypass application and the priming volume in the circuit. Further, body fluid balance after the operation was calculated, and its relation to BV was studied. As to the correlation coefficient and inclination of the regression line, they were 0.77 and 0.849 with CO, and 0.821 and 0.844 with BV, respectively. Upon completion of the operation BV decreased, but increased again 4h and 12h later, although the body fluid balance was negative. CO and BV determined by the pulse dye densitometry favorably correlated with those determined by other methods. Immediately after the operation BV decreased, but then increased in the course of time, although the body fluid balance was negative.
@Jpn. J. Cardiovasc. Surg. 29: 156-160 (2000)