@media print, all and (min-width: 710px) {
  .is-hidden_pc {
    display: none;
  }
}
@media print, all and (max-width: 750px) {
  .is-hidden_sp {
    display: none;
  }
}
.image-clip {
  clip-path: polygon(0 30%, 100% 2%, 100% 70%, 0 100%);
}

.deco-shape span {
  display: inline-block;
  clip-path: polygon(0 30%, 100% 2%, 100% 70%, 0 100%);
  background-color: #4bbdce;
  position: absolute;
  z-index: -1;
}
.deco-shape span:first-child {
  width: 150px;
  height: 147px;
  bottom: -330px;
  right: -60px;
}
.deco-shape span:last-child {
  width: 96px;
  height: 95px;
  bottom: -395px;
  right: 70px;
}

#mainv {
  position: relative;
  background: url(../images/home/mainv/image/image03.jpg) no-repeat center top/cover;
}
#mainv .slick-list,
#mainv .slick-track,
#mainv .slick-slide,
#mainv .slick-slide > div {
  width: 100%;
  height: 100%;
}
#mainv .image-box {
  width: 100%;
  margin: 0;
  position: relative;
  aspect-ratio: 1280/780;
  /* TRANSITION */
  -webkit-transition: background 0.3s;
  -moz-transition: background 0.3s;
  -o-transition: background 0.3s;
  transition: background 0.3s;
}
#mainv .image-box .image {
  width: 100%;
  height: 100%;
  position: relative;
  background-size: cover;
  background-position: center;
  background-repeat: no-repeat;
  z-index: 2;
}
#mainv .image-box .image.image01 {
  background-image: url(../images/home/mainv/image/image01.jpg);
}
#mainv .image-box .image.image02 {
  background-image: url(../images/home/mainv/image/image02.jpg);
}
#mainv .image-box .image.image03 {
  background-image: url(../images/home/mainv/image/image03.jpg);
}
#mainv .main-inner {
  width: 87.5vw;
  min-width: 1000px;
  margin: auto;
  position: absolute;
  left: 0;
  right: 0;
  top: 50%;
  transform: translate(0, calc(-50% + 65px));
  display: flex;
  justify-content: space-between;
  align-items: flex-end;
  z-index: 3;
}
#mainv .catch-box {
  color: #fff;
}
#mainv .catch-box p .en {
  display: block;
  font-family: "Bitter", serif;
  font-size: max(80px, 7.1vw);
  /*92px*/
  line-height: 1;
  margin-bottom: 30px;
  text-shadow: 0px 2px 0px #000, 0 0 1px #000, 0 0 12px #000;
}
#mainv .catch-box p .ja {
  font-weight: 600;
  font-size: max(20px, 1.8vw);
  letter-spacing: 0.1em;
  text-shadow: 0px 2px 0px #000, 0 0 1px #000, 0 0 12px #000;
}

#home-lead {
  background: #4bbdce;
  padding-bottom: 95px;
  padding-top: 5px;
}
#home-lead .imgwrap-box {
  position: relative;
  margin-bottom: 0 !important;
  z-index: 2;
}
#home-lead .imgwrap-box .image {
  position: absolute;
  background-size: cover;
  clip-path: polygon(0 30%, 100% 0%, 100% 71%, 0 100%);
}
#home-lead .imgwrap-box .image.image01 {
  top: -282px;
  right: 0;
  width: 640px;
  height: 581px;
  background-image: url(../images/home/desc-image01.jpg);
}
#home-lead .imgwrap-box .image.image02 {
  bottom: -199px;
  right: 370px;
  width: 394px;
  height: 345px;
  background-image: url(../images/home/desc-image02.jpg);
}
#home-lead .imgwrap-box .image.image03 {
  bottom: -192px;
  right: 0;
  width: 294px;
  height: 280px;
  background-image: url(../images/home/desc-image03.jpg);
  clip-path: polygon(0 27%, 100% 0%, 100% 73%, 0 100%);
}
#home-lead .imgwrap-box .image .sign {
  position: absolute;
  top: 50%;
  left: 14%;
  transform: translate(0, -50%);
  font-weight: 500;
  font-size: 125%;
  display: block;
  line-height: 1.1;
  color: #fff;
  text-shadow: 0px 1px 2px #000, 0 0 2em rgba(0, 0, 0, 0.7), 0 0 0.5em rgba(0, 0, 0, 0.7);
  text-align: right;
  /*20px*/
}
#home-lead .imgwrap-box .image .sign .ja {
  display: block;
  font-weight: 600;
  margin-top: 5px;
  font-size: 150%;
  /*30px*/
}
#home-lead .imgwrap-box .image .sign .en {
  font-family: "Bitter", serif;
  font-size: 250%;
  /*50px*/
}
#home-lead .text-box {
  color: #fff;
  width: 416px;
}
#home-lead .text-box .text {
  margin-bottom: 20px;
}
#home-lead .text-box .text em {
  display: inline-block;
  font-size: 162.5%;
  font-weight: 700;
  margin-bottom: 12px;
  margin-left: -15px;
}
#home-lead .text-box .text span span {
  font-size: 150%;
  font-weight: 700;
}
#home-lead.skewed:after {
  top: 1px;
  z-index: 1;
  background: #4bbdce;
  transform: skewY(0deg) translateY(-100%);
  aspect-ratio: 1280/345;
  clip-path: polygon(100% 0, 0 100%, 100% 100%);
}

#home-news {
  padding-top: 130px;
  background: #ffffff;
  z-index: 1;
  position: relative;
  margin-bottom: 275px;
}
#home-news h2 {
  width: 220px;
}
#home-news .news-box {
  display: flex;
  gap: 40px;
  position: relative;
}
#home-news .news-box dl {
  padding-top: 20px;
  width: calc(100% - 260px);
}
#home-news .news-box dl dd:not(:last-of-type) {
  margin-bottom: 40px;
}
#home-news .news-box .btn-type01 {
  position: absolute;
  left: 0px;
  top: 140px;
}

#home-movie {
  margin-bottom: 160px;
}
#home-movie .text-box {
  display: flex;
  justify-content: space-between;
  gap: 75px;
}
#home-movie .text-box p {
  width: 625px;
  padding-top: 18px;
}
#home-movie .skewed:after {
  height: 380px;
}
#home-movie .media-box {
  display: flex;
  justify-content: space-between;
  position: relative;
}
#home-movie .video-box {
  width: 700px;
}
#home-movie .video-box video {
  width: 100%;
}
#home-movie .image-box {
  z-index: 2;
}
#home-movie .image-box .image {
  background-size: cover;
  background-position: center;
  background-repeat: no-repeat;
  position: absolute;
}
#home-movie .image-box .image.image01 {
  right: 0;
  bottom: -145px;
  width: 330px;
  height: 326px;
  background-image: url(../images/home/image-movie01.jpg);
}
#home-movie .image-box .image.image02 {
  top: -42px;
  right: -65px;
  width: 225px;
  height: 220px;
  background-image: url(../images/home/image-movie02.jpg);
  z-index: -1;
}

#home-features {
  overflow-x: clip;
}
#home-features .title-level01 {
  margin-bottom: 15px;
}
#home-features .skewed:after {
  height: 380px;
  transform: skewY(-15deg) translateY(-44%);
  z-index: 1;
  background: rgba(75, 189, 206, 0.15);
}
#home-features .container-inner {
  position: relative;
}
#home-features .image-float {
  z-index: 2;
  position: absolute;
  top: -230px;
  right: -180px;
}
#home-features .image-float .image {
  background-size: cover;
  background-position: center;
  background-repeat: no-repeat;
  position: absolute;
}
#home-features .image-float .image.image01 {
  right: 0;
  top: 0;
  width: 330px;
  height: 326px;
  background-image: url(../images/home/image-movie01.jpg);
}
#home-features .image-float .image.image02 {
  top: 57px;
  right: 300px;
  width: 225px;
  height: 220px;
  background-image: url(../images/home/image-movie02.jpg);
  z-index: -1;
}
#home-features .features-list {
  width: min(1280px, 100%);
  margin: auto;
}
#home-features .features-list li {
  display: flex;
  justify-content: flex-end;
  align-items: flex-start;
  gap: 70px;
}
#home-features .features-list li .image-box {
  z-index: 1;
  width: 50%;
  height: 561px;
  padding-right: 60px;
  box-sizing: border-box;
  background-repeat: no-repeat;
  background-position: center;
  background-size: cover;
  clip-path: polygon(0 30%, 100% 0%, 100% 70%, 0 100%);
}
#home-features .features-list li .text-box {
  width: 410px;
  padding-top: 50px;
}
#home-features .features-list li .text-box h3 {
  font-family: "Bitter", serif;
  font-size: 150%;
  /*24px*/
  line-height: 1;
  margin-bottom: 15px;
  color: #4bbdce;
  letter-spacing: 0.02em;
}
#home-features .features-list li .text-box em {
  display: inline-block;
  margin-bottom: 15px;
  font-size: 162.5%;
  /*26px*/
  font-weight: 600;
}
#home-features .features-list li .text-box .btn-type01 {
  margin-top: 35px;
}
#home-features .features-list li:nth-child(2n+1) {
  flex-direction: row-reverse;
}
#home-features .features-list li.pioneer .image-box {
  background-image: url(../images/home/image-feature01.jpg);
}
#home-features .features-list li.treatment .text-box {
  padding-top: 42px;
}
#home-features .features-list li.treatment .image-box {
  margin-bottom: 125px;
  margin-top: -190px;
  background-image: url(../images/home/image-feature02.jpg);
}
#home-features .features-list li.clinical-research .text-box {
  padding-top: 37px;
}
#home-features .features-list li.clinical-research .image-box {
  background-image: url(../images/home/image-feature03.jpg);
}
#home-features .features-list li.basic-research {
  position: relative;
}
#home-features .features-list li.basic-research .text-box {
  padding-top: 70px;
}
#home-features .features-list li.basic-research .image-box {
  margin-bottom: 120px;
  margin-top: -160px;
  background-image: url(../images/home/image-feature04.jpg);
}
#home-features .features-list li.basic-research .deco-shape {
  position: absolute;
  bottom: 0;
}
#home-features .features-list li.basic-research .deco-shape span {
  z-index: 1;
}
#home-features .features-list li.basic-research .deco-shape span:first-child {
  bottom: 120px;
  right: 160px;
}
#home-features .features-list li.basic-research .deco-shape span:last-child {
  bottom: 0px;
  right: 288px;
}

@media all and (min-width: 751px) {
  /* MAINV */
  body.home #mainv #pcnav-filter {
    height: 700px;
  }
}
@media only screen and (max-width: 750px) {
  /* MAINV */
  #mainv .image-box {
    aspect-ratio: 750/780;
  }
  #modal-video {
    width: 130px;
  }
  #home-lead {
    padding-bottom: 50px;
    padding-top: 0px;
  }
  #home-lead .main-inner {
    position: absolute;
    min-width: auto;
    display: flex;
    flex-direction: column;
    gap: 30px;
    position: relative;
    z-index: 3;
    padding: 20px 20px 0;
  }
  #home-lead .catch-box {
    color: #fff;
    position: relative;
    z-index: 3;
  }
  #home-lead .catch-box p .en {
    display: block;
    font-family: "Bitter", serif;
    font-size: min(100px, 10vw);
    line-height: 1.2;
    margin-bottom: 10px;
  }
  #home-lead .catch-box p .ja {
    font-size: max(20px, 1.8vw);
    line-height: 1;
    font-weight: 600;
    letter-spacing: 0.1em;
    text-shadow: 0px 2px 0px #4bbdce, 0 0 1px #4bbdce, 0 0 12px #4bbdce;
  }
  #home-lead .imgwrap-box {
    position: relative;
    margin-bottom: 0 !important;
    z-index: 2;
  }
  #home-lead .imgwrap-box .image-box {
    padding-bottom: 25vw;
    position: relative;
  }
  #home-lead .imgwrap-box .image {
    position: static;
    background-size: cover;
    clip-path: polygon(0 30%, 100% 0%, 100% 71%, 0 100%);
    margin-top: -50%;
  }
  #home-lead .imgwrap-box .image.image01 {
    width: 78vw;
    height: 84vw;
    margin-right: 0;
    margin-left: auto;
    position: relative;
    top: 0;
  }
  #home-lead .imgwrap-box .image.image02 {
    bottom: 0;
    left: 30px;
    right: auto;
    width: 50vw;
    height: 50vw;
    position: absolute;
  }
  #home-lead .imgwrap-box .image.image03 {
    bottom: 20px;
    right: 20px;
    width: 30.66vw;
    height: 31.66vw;
    position: absolute;
  }
  #home-lead .imgwrap-box .image .sign {
    font-size: 100%;
    top: 50%;
    left: 40%;
    transform: translate(-40%, -40%);
    text-align: left;
  }
  #home-lead .imgwrap-box .image .sign .ja {
    font-size: 125%;
    margin-top: 15px;
  }
  #home-lead .imgwrap-box .image .sign .en {
    font-size: 162.5%;
  }
  #home-lead .text-box {
    color: #fff;
    width: auto;
  }
  #home-lead .text-box .text {
    margin-bottom: 20px;
    padding: 0 20px;
  }
  #home-lead .text-box .text em {
    font-size: max(125%, 5vw);
    margin-left: -10px;
  }
  #home-lead.skewed:after {
    content: none;
  }
  #home-news {
    padding-top: 40px;
    margin-bottom: 65px;
  }
  #home-news h2 {
    width: auto;
    margin: 0;
  }
  #home-news .news-box {
    flex-direction: column;
    gap: 20px;
  }
  #home-news .news-box dl {
    width: auto;
  }
  #home-news .news-box dl dd:not(:last-of-type) {
    margin-bottom: 25px;
  }
  #home-news .news-box .btn-type01 {
    position: static;
    left: 0px;
    top: 140px;
  }
  #home-movie {
    margin-bottom: 160px;
  }
  #home-movie .text-box {
    flex-direction: column;
    gap: 0px;
    margin-bottom: 40px;
  }
  #home-movie .text-box p {
    width: auto;
    padding-top: 0px;
  }
  #home-movie .skewed:after {
    height: 380px;
  }
  #home-movie .media-box {
    display: flex;
    justify-content: space-between;
    position: relative;
  }
  #home-movie .video-box {
    width: 700px;
  }
  #home-movie .video-box video {
    width: 100%;
  }
  #home-movie .image-box {
    z-index: 2;
  }
  #home-movie .image-box .image {
    background-size: cover;
    background-position: center;
    background-repeat: no-repeat;
    position: absolute;
  }
  #home-movie .image-box .image.image01 {
    right: 0;
    bottom: -145px;
    width: 330px;
    height: 326px;
    background-image: url(../images/home/image-movie01.jpg);
  }
  #home-movie .image-box .image.image02 {
    top: -42px;
    right: -65px;
    width: 225px;
    height: 220px;
    background-image: url(../images/home/image-movie02.jpg);
  }
  #home-features .skewed:after {
    height: 260px;
    transform: skewY(-15deg) translateY(-24%);
  }
  #home-features .features-list {
    width: auto;
    padding: 0 20px;
  }
  #home-features .features-list li {
    flex-direction: column-reverse !important;
    gap: 0px;
  }
  #home-features .features-list li .image-box {
    width: 100%;
    height: 80vw;
    padding-right: 0px;
  }
  #home-features .features-list li .text-box {
    width: auto;
    padding-top: 0 !important;
    margin-top: -30px;
  }
  #home-features .features-list li .text-box h3 {
    margin-bottom: 5px;
    text-align: right;
  }
  #home-features .features-list li .text-box em {
    display: block;
    text-align: right;
    margin-bottom: 15px;
    font-size: 125%;
    /*20px*/
  }
  #home-features .features-list li .text-box .btn-type01 {
    margin-top: 35px;
  }
  #home-features .features-list li.treatment .image-box {
    margin-bottom: 0;
    margin-top: 0;
  }
  #home-features .features-list li:not(:last-child) {
    margin-bottom: 40px;
  }
  #home-features .features-list li.basic-research {
    position: relative;
  }
  #home-features .features-list li.basic-research .image-box {
    margin-bottom: 0px;
    margin-top: 0px;
  }
  #home-features .features-list li.basic-research .deco-shape {
    position: absolute;
    bottom: 0;
  }
  #home-features .features-list li.basic-research .deco-shape span {
    z-index: 1;
  }
  #home-features .features-list li.basic-research .deco-shape span:first-child {
    bottom: 120px;
    right: 160px;
  }
  #home-features .features-list li.basic-research .deco-shape span:last-child {
    bottom: 0px;
    right: 288px;
  }
}