{"id":3648,"date":"2024-10-12T21:54:50","date_gmt":"2024-10-12T12:54:50","guid":{"rendered":"https:\/\/plaza.umin.ac.jp\/~OIO\/?p=3648"},"modified":"2024-10-12T22:58:51","modified_gmt":"2024-10-12T13:58:51","slug":"%e3%83%af%e3%82%af%e3%83%81%e3%83%b3%e3%81%ae%e3%82%b7%e3%82%a7%e3%83%87%e3%82%a3%e3%83%b3%e3%82%b0%e3%81%ab%e3%81%a4%e3%81%84%e3%81%a6%e2%91%a0","status":"publish","type":"post","link":"https:\/\/plaza.umin.ac.jp\/~OIO\/?p=3648","title":{"rendered":"\u30ef\u30af\u30c1\u30f3\u306e\u30b7\u30a7\u30c7\u30a3\u30f3\u30b0\u306b\u3064\u3044\u3066\u2460"},"content":{"rendered":"\n

\u306f\u3058\u3081\u306b<\/h3>\n\n\n\n

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\u4e00\u822c\u7684\u306b\u306f\u30ef\u30af\u30c1\u30f3\u306e\u30b7\u30a7\u30c7\u30a3\u30f3\u30b0\u3068\u306f\u3001\u30ef\u30af\u30c1\u30f3\u3092\u63a5\u7a2e\u3057\u305f\u4eba\u304c\u3001\u30ef\u30af\u30c1\u30f3\u7531\u6765\u306e\u30a6\u30a4\u30eb\u30b9\u7c92\u5b50\u3092\u4f53\u5916\u306b\u6392\u51fa\u3059\u308b\u73fe\u8c61\u3092\u6307\u3057\u307e\u3059\u3002\u3053\u308c\u306f\u7279\u306b\u751f\u30ef\u30af\u30c1\u30f3\u306b\u95a2\u9023\u3057\u3066\u898b\u3089\u308c\u308b\u3053\u3068\u304c\u591a\u3044\u3067\u3059\u3002\u4f8b\u3048\u3070\u3001\u30ed\u30bf\u30a6\u30a4\u30eb\u30b9\u30ef\u30af\u30c1\u30f3\u306b\u95a2\u3059\u308b\u7814\u7a76\u3067\u306f\u3001\u30b7\u30a7\u30c7\u30a3\u30f3\u30b0\u304c\u4e00\u822c\u7684\u3067\u3042\u308a\u3001\u9577\u671f\u9593\u306b\u308f\u305f\u3063\u3066\u7d9a\u304f\u3053\u3068\u304c\u3042\u308b\u3068\u5831\u544a\u3055\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n

\u5177\u4f53\u7684\u306a\u4f8b\u3092\u6319\u3052\u308b\u3068\u3001\u4e94\u4fa1\u30ed\u30bf\u30a6\u30a4\u30eb\u30b9\u30ef\u30af\u30c1\u30f3\uff08RV5\uff09\u306e\u521d\u56de\u63a5\u7a2e\u5f8c\u300121.4%\u306e\u4e73\u5150\u3067\u6700\u59279\u65e5\u9593\u306b\u308f\u305f\u3063\u3066\u30b7\u30a7\u30c7\u30a3\u30f3\u30b0\u304c\u78ba\u8a8d\u3055\u308c\u307e\u3057\u305f(Yen et al., 2011)\u3002\u307e\u305f\u3001\u5225\u306e\u7814\u7a76\u3067\u306f\u3001\u521d\u56de\u63a5\u7a2e\u5f8c5\u301c10\u65e5\u306793%\u306e\u4e73\u5150\u304c\u30ef\u30af\u30c1\u30f3\u95a2\u9023\u306e\u7c92\u5b50\u3092\u6392\u51fa\u3057\u3001\u305d\u306e\u4e2d\u3067G1\u3068\u3044\u3046\u907a\u4f1d\u5b50\u578b\u304c\u4e3b\u306b\u898b\u3089\u308c\u307e\u3057\u305f (Markkula et al., 2019)\u3002<\/p>\n\n\n\n

RV5\u3068Rotarix\uff08RV2\uff09\u3068\u3044\u30462\u7a2e\u985e\u306e\u30ed\u30bf\u30a6\u30a4\u30eb\u30b9\u30ef\u30af\u30c1\u30f3\u3092\u6bd4\u8f03\u3057\u305f\u7814\u7a76\u3067\u306f\u3001\u30b7\u30a7\u30c7\u30a3\u30f3\u30b0\u306e\u5272\u5408\u306f\u4f3c\u3066\u3044\u308b\u3082\u306e\u306e\u3001RV2\u3092\u63a5\u7a2e\u3057\u305f\u4eba\u306e\u65b9\u304c\u3088\u308a\u591a\u304f\u306e\u30a6\u30a4\u30eb\u30b9\u3092\u6392\u51fa\u3057\u3066\u3044\u308b\u3053\u3068\u304c\u5206\u304b\u308a\u307e\u3057\u305f(Hsieh et al., 2014)\u3002<\/p>\n\n\n\n

\u4e00\u65b9\u3067\u3001\u7d4c\u53e3\u72c2\u72ac\u75c5\u30ef\u30af\u30c1\u30f3\uff08SPBN GASGAS\uff09\u306b\u95a2\u3059\u308b\u7814\u7a76\u3067\u306f\u3001\u69d8\u3005\u306a\u52d5\u7269\u7a2e\u306b\u304a\u3044\u306624\u6642\u9593\u4ee5\u4e0a\u611f\u67d3\u6027\u30a6\u30a4\u30eb\u30b9\u306e\u6d3b\u767a\u306a\u30b7\u30a7\u30c7\u30a3\u30f3\u30b0\u306f\u898b\u3089\u308c\u305a\u3001\u6c34\u5e73\u611f\u67d3\u306e\u30ea\u30b9\u30af\u306f\u6700\u5c0f\u9650\u3067\u3042\u308b\u3053\u3068\u304c\u793a\u5506\u3055\u308c\u3066\u3044\u307e\u3059 (Vos et al., 2018)\u3002<\/p>\n\n\n\n

\u3053\u308c\u3089\u306e\u7814\u7a76\u7d50\u679c\u306f\u3001\u30ef\u30af\u30c1\u30f3\u306e\u7a2e\u985e\u3084\u63a5\u7a2e\u3092\u53d7\u3051\u308b\u7a2e\u306b\u3088\u3063\u3066\u3001\u30b7\u30a7\u30c7\u30a3\u30f3\u30b0\u306e\u30d1\u30bf\u30fc\u30f3\u304c\u5927\u304d\u304f\u7570\u306a\u308b\u3053\u3068\u3092\u793a\u3057\u3066\u3044\u307e\u3059\u3002\u30ef\u30af\u30c1\u30f3\u306e\u30b7\u30a7\u30c7\u30a3\u30f3\u30b0\u306b\u3064\u3044\u3066\u7406\u89e3\u3092\u6df1\u3081\u308b\u3053\u3068\u3067\u3001\u30ef\u30af\u30c1\u30f3\u63a5\u7a2e\u306b\u95a2\u3059\u308b\u4e0d\u5b89\u3092\u8efd\u6e1b\u3057\u3001\u3088\u308a\u5b89\u5fc3\u3057\u3066\u63a5\u7a2e\u3092\u53d7\u3051\u308b\u3053\u3068\u304c\u3067\u304d\u308b\u3067\u3057\u3087\u3046\u3002<\/p>\n\n\n\n

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\u4e0b\u306e\u56f3\u306f\u5831\u544a\u3055\u308c\u305fSARS-CoV-2\u30a6\u30a4\u30eb\u30b9\u8d77\u6e90\u682a\u306e\u907a\u4f1d\u5b50\u914d\u5217\uff08Severe acute respiratory syndrome coronavirus 2 isolate Wuhan-Hu-1, co – Nucleotide – NCBI (nih.gov)<\/a>\uff09\u3092\u57fa\u306b\u907a\u4f1d\u5b50\u306e\u914d\u7f6e\u3092\u8272\u5206\u3051\u3057\u305f\u3082\u306e\u3067\u3059\u3002\u56f3\u3067\u306fORF1ab\u3092\u4e00\u3064\u306e\u8272\u3067\u5857\u3063\u3066\u3044\u307e\u3059\u304c\u3001ORF1ab\u306e\u9818\u57df\u306b\u306f\u3055\u3089\u306b\u3044\u304f\u3064\u304b\u306e\u30bf\u30f3\u30d1\u30af\u8cea\u3092\u30b3\u30fc\u30c9\u3059\u308b\u9818\u57df\u304c\u542b\u307e\u308c\u3066\u3044\u307e\u3059\u3002\u591a\u304f\u306e\u907a\u4f1d\u5b50\u304c\u63c3\u3063\u3066\u521d\u3081\u3066\u30a6\u30a4\u30eb\u30b9\u7c92\u5b50\u3068\u3057\u3066\u306e\u69cb\u9020\u304c\u69cb\u6210\u3055\u308c\u308b\u305f\u3081\u3001S\u30bf\u30f3\u30d1\u30af\u8cea\u3092\u30b3\u30fc\u30c9\u3059\u308b\u907a\u4f1d\u5b50\u3060\u3051\u3067\u30a6\u30a4\u30eb\u30b9\u7c92\u5b50\u306e\u69cb\u9020\u3092\u5f62\u6210\u3059\u308b\u3053\u3068\u306f\u96e3\u3057\u3044\u3068\u8003\u3048\u3089\u308c\u307e\u3059\u3002<\/p>\n\n\n\n

\"\"<\/figure>\n\n\n\n

\u305d\u308c\u306b\u3082\u304b\u304b\u308f\u3089\u305a\u3001\u30ec\u30d7\u30ea\u30b3\u30f3\u30ef\u30af\u30c1\u30f3\u306b\u30b7\u30a7\u30c7\u30a3\u30f3\u30b0\u306e\u61f8\u5ff5\u304c\u3042\u308b\u3068\u4e3b\u5f35\u3059\u308b\u30a6\u30a7\u30d6\u30b5\u30a4\u30c8<\/a>\u304c\u5b58\u5728\u3057\u307e\u3059\u304c\u3001\u6839\u62e0\u30c7\u30fc\u30bf\u306f\u76f4\u63a5\u306f\u793a\u3055\u308c\u3066\u3044\u307e\u305b\u3093\u3002\u5f53\u8a72\u58f0\u660e\u3067\u306f\u3001Seneff, S., & Nigh, G. (2021). Worse than the disease? Reviewing some possible unintended consequences of the mRNA vaccines against COVID-19. International Journal of Vaccine Theory, Practice, and Research, 2(1), 38-79.\u306e\u6587\u732e\u3092\u5f15\u7528\u3057\u3066\u3044\u307e\u3059\u304c\u3001\u3053\u306e\u6587\u732e\u306fPubMed\u306b\u306f\u63b2\u8f09\u3055\u308c\u3066\u3044\u306a\u3044\u305f\u3081\u3001\u691c\u7d22\u306b\u304b\u304b\u308a\u307e\u305b\u3093\u3002<\/p>\n\n\n\n

Seneff\u6c0f\u306e\u6240\u5c5e\u306fComputer Science and Artificial Intelligence Laboratory, MIT, Cambridge MA, 02139, USA\u3067\u3042\u308a\u3001\u30a6\u30a4\u30eb\u30b9\u3084\u30ef\u30af\u30c1\u30f3\u306e\u5c02\u9580\u65bd\u8a2d\u3067\u306f\u3042\u308a\u307e\u305b\u3093\u3002\u6587\u732e\u5185\u306b\u3082\u3001\u5b9f\u9a13\u3084\u81e8\u5e8a\u8a66\u9a13\u3067\u76f4\u63a5\u30a6\u30a4\u30eb\u30b9\u306e\u30b7\u30a7\u30c7\u30a3\u30f3\u30b0\u3092\u78ba\u8a8d\u3057\u305f\u30c7\u30fc\u30bf\u306f\u8a18\u8f09\u3055\u308c\u3066\u3044\u307e\u305b\u3093\u3002\u307e\u305f\u3001\u30ef\u30af\u30c1\u30f3\u306e\u9818\u57df\u3067\u554f\u984c\u3068\u306a\u3063\u3066\u3044\u308b\u306e\u306f\u30a6\u30a4\u30eb\u30b9\u7c92\u5b50\u306e\u30b7\u30a7\u30c7\u30a3\u30f3\u30b0\u3067\u3059\u304c\u3001Seneff\u6c0f\u306e\u6587\u732e\u3067\u306f\u30bf\u30f3\u30d1\u30af\u8cea\u306e\u30b7\u30a7\u30c7\u30a3\u30f3\u30b0\u306b\u3064\u3044\u3066\u8ad6\u3058\u3066\u3044\u307e\u3059\u3002\u819c\u30bf\u30f3\u30d1\u30af\u8cea\u304c\u7d30\u80de\u819c\u8868\u9762\u3067\u5207\u65ad\u3055\u308c\u3066\u7d30\u80de\u304b\u3089\u96e2\u308c\u308b\u73fe\u8c61\u3092\u30b7\u30a7\u30c7\u30a3\u30f3\u30b0\u3068\u547c\u3076\u7814\u7a76\u9818\u57df\u3082\u3042\u308a\u307e\u3059\u304c\u3001\u4eba\u304b\u3089\u4eba\u3078\u306e\u4f1d\u64ad\u3092\u554f\u984c\u306b\u3057\u3066\u3044\u308b\u305f\u3081\u3001\u819c\u30bf\u30f3\u30d1\u30af\u8cea\u306e\u30b7\u30a7\u30c7\u30a3\u30f3\u30b0\u3068\u306f\u7570\u306a\u308b\u610f\u5473\u5408\u3044\u3067\u3059\u3002\u6839\u62e0\u306e\u6709\u7121\u306f\u5f15\u7528\u6587\u732e\u3092\u78ba\u8a8d\u3059\u308b\u5fc5\u8981\u304c\u3042\u308a\u307e\u3059\u304c\u3001\u4eee\u306b\u30b9\u30d1\u30a4\u30af\u30bf\u30f3\u30d1\u30af\u8cea\u304c\u88ab\u63a5\u7a2e\u8005\u304b\u3089\u653e\u51fa\u3055\u308c\u305f\u3068\u3057\u3066\u3082\u3001\u305d\u308c\u304c\u30a6\u30a4\u30eb\u30b9\u3068\u3057\u3066\u611f\u67d3\u3057\u3001COVID-19\u3092\u767a\u75c5\u3059\u308b\u3068\u306f\u8003\u3048\u306b\u304f\u3044\u3067\u3059\u3002<\/p>\n\n\n\n

Seneff\u6c0f\u306f\u3001\u5f93\u6765\u306e\u30ef\u30af\u30c1\u30f3\u306e\u5b89\u5168\u6027\u3067\u554f\u984c\u306b\u306a\u308b\u30b7\u30a7\u30c7\u30a3\u30f3\u30b0\u3068\u306f\u7570\u306a\u308b\u610f\u5473\u3067\u300c\u30b7\u30a7\u30c7\u30a3\u30f3\u30b0\u300d\u3092\u4f7f\u7528\u3057\u3066\u3044\u308b\u3053\u3068\u304c\u660e\u3089\u304b\u306b\u306a\u308a\u307e\u3057\u305f\u3002\u7570\u696d\u7a2e\u9593\u3067\u540c\u3058\u8a00\u8449\u3092\u7570\u306a\u308b\u610f\u5473\u3067\u4f7f\u7528\u3059\u308b\u3053\u3068\u306f\u3042\u308a\u5f97\u308b\u305f\u3081\u3001\u305d\u306e\u8a00\u8449\u306e\u5171\u901a\u8a8d\u8b58\u3092\u6301\u305f\u306a\u3044\u9650\u308a\u8b70\u8ad6\u306f\u6210\u7acb\u3057\u307e\u305b\u3093\u3002\u307e\u305a\u3001\u3053\u306e\u7814\u7a76\u8005\u304c\u3069\u306e\u3088\u3046\u306a\u30c7\u30fc\u30bf\u3092\u57fa\u306b\u3001\u3069\u306e\u3088\u3046\u306a\u73fe\u8c61\u3092\u300c\u30b7\u30a7\u30c7\u30a3\u30f3\u30b0\u300d\u3068\u79f0\u3057\u3066\u3044\u308b\u306e\u304b\u3092\u660e\u78ba\u306b\u3059\u308b\u5fc5\u8981\u304c\u3042\u308a\u307e\u3059\u3002<\/p>\n\n\n\n

\u3082\u3046\u4e00\u70b9\u6c17\u306b\u306a\u308b\u70b9\u304c\u3042\u308a\u307e\u3059\u3002\u305d\u308c\u306fSeneff\u6c0f\u306e\u8ad6\u6587\u306fmRNA\u30ef\u30af\u30c1\u30f3\u3092\u5bfe\u8c61\u306b\u3057\u3066\u8a18\u8ff0\u3055\u308c\u3066\u3044\u308b\u70b9\u3067\u3059\u3002\u30ec\u30d7\u30ea\u30b3\u30f3\u30ef\u30af\u30c1\u30f3\u3067\u306e\u61f8\u5ff5\u306b\u76f4\u306b\u7d50\u3073\u3064\u3051\u3066\u826f\u3044\u3082\u306e\u304b\u3002\u5c11\u306a\u304f\u3068\u3082\u3001\u5f93\u6765\u306eRNA\u30ef\u30af\u30c1\u30f3\u3067\u306f\u554f\u984c\u3068\u3057\u306a\u304b\u3063\u305f\u306b\u3082\u304b\u304b\u308f\u3089\u305a\u3001\u30ec\u30d7\u30ea\u30b3\u30f3\u30ef\u30af\u30c1\u30f3\u3067\u306f\u61f8\u5ff5\u3067\u3042\u308b\u3068\u3059\u308b\u306e\u3067\u3042\u308c\u3070\u3001\u9055\u3046\u30ef\u30af\u30c1\u30f3\u306b\u3064\u3044\u3066\u306e\u60c5\u5831\u3092\u5f15\u7528\u3057\u3066\u6839\u62e0\u3068\u3059\u308b\u3053\u3068\u306e\u6b63\u5f53\u6027\u306e\u8aac\u660e\u306f\u898b\u3066\u307f\u305f\u3044\u3068\u3053\u308d\u3067\u3059\u3002<\/p>\n\n\n\n

Seneff\u6c0f\u306f\u3001\u30ec\u30d7\u30ea\u30b3\u30f3\u30ef\u30af\u30c1\u30f3\u306b\u3064\u3044\u3066\u8ad6\u3058\u3066\u3044\u308b\u8a33\u3067\u306f\u306a\u3044\u306e\u3067\u3059\u304c\u3001mRNA\u30ef\u30af\u30c1\u30f3\u3067\u306e\u300c\u30b9\u30d1\u30a4\u30af\u30bf\u30f3\u30d1\u30af\u8cea\u306e\u30b7\u30a7\u30c7\u30a3\u30f3\u30b0\u300d\u3092\u8ad6\u3058\u3066\u3044\u307e\u3057\u305f\u3002\u305d\u306e\u76f4\u63a5\u7684\u306a\u6839\u62e0\u3068\u306a\u308b\u3088\u3046\u306a\u89b3\u5bdf\u306e\u8a18\u9332\u30c7\u30fc\u30bf\u306f\u8a18\u8f09\u3055\u308c\u3066\u304a\u3089\u305a\u3001\u4ee3\u308f\u308a\u306bLucchetti\u6c0f\u3089\u306e\u8ad6\u6587(Lucchetti et al., 2021) \u3092\u5f15\u7528\u3057\u3066\u3044\u307e\u3059\u3002Lucchetti\u6c0f\u3089\u306e\u8ad6\u6587\u306fPubMed\u306b\u63b2\u8f09\u3055\u308c\u3066\u3044\u307e\u3059\u306e\u3067\u3001\u3053\u306e\u8a18\u4e8b\u3067\u3082References\u306e\u4e2d\u306b\u66f8\u8a8c\u4e8b\u9805\u3092\u8a18\u8f09\u3057\u3066\u304a\u304d\u307e\u3059\u3002Lucchetti\u6c0f\u3089\u306e\u8ad6\u6587\u3067\u306f\u3069\u306e\u3088\u3046\u306a\u7814\u7a76\u304c\u306a\u3055\u308c\u3066\u3044\u308b\u306e\u304b\u306f\u5225\u8a18\u4e8b<\/a>\u306b\u3057\u3088\u3046\u3068\u601d\u3044\u307e\u3059\u304c\u3001\u3053\u306eSeneff\u6c0f\u306e\u6587\u732e\u306e\u30b7\u30a7\u30c7\u30a3\u30f3\u30b0\u5468\u308a\u306e\u90e8\u5206\u3092\u3082\u3046\u5c11\u3057\u3060\u3051\u898b\u3066\u304a\u3053\u3046\u3068\u601d\u3044\u307e\u3059\u3002<\/p>\n\n\n\n

\"\"<\/figure>\n\n\n\n

\u3053\u306e\u90e8\u5206\u3092\u6a5f\u68b0\u7ffb\u8a33\u3057\u307e\u3057\u305f\u3002<\/p>\n\n\n\n

\n

\u30a4\u30f3\u30bf\u30fc\u30cd\u30c3\u30c8\u4e0a\u3067\u306f\u3001\u30ef\u30af\u30c1\u30f3\u63a5\u7a2e\u8005\u304c\u8fd1\u304f\u306b\u3044\u308b\u672a\u63a5\u7a2e\u8005\u306b\u75c5\u6c17\u3092\u5f15\u304d\u8d77\u3053\u3059\u53ef\u80fd\u6027\u306b\u3064\u3044\u3066\u306e\u8b70\u8ad6\u304c\u591a\u304f\u3042\u308a\u307e\u3059\u3002\u3053\u308c\u306f\u4fe1\u3058\u304c\u305f\u3044\u304b\u3082\u3057\u308c\u307e\u305b\u3093\u304c\u3001\u813e\u81d3\u306e\u6a39\u72b6\u7d30\u80de\u304b\u3089\u8aa4\u3063\u3066\u6298\u308a\u305f\u305f\u307e\u308c\u305f\u30b9\u30d1\u30a4\u30af\u30bf\u30f3\u30d1\u30af\u8cea\u3092\u542b\u3080\u30a8\u30af\u30bd\u30bd\u30fc\u30e0\u304c\u653e\u51fa\u3055\u308c\u3001\u4ed6\u306e\u30d7\u30ea\u30aa\u30f3\u518d\u69cb\u6210\u30bf\u30f3\u30d1\u30af\u8cea\u3068\u8907\u5408\u4f53\u3092\u5f62\u6210\u3059\u308b\u3053\u3068\u3067\u8d77\u3053\u308a\u5f97\u308b\u3068\u3044\u3046\u3082\u3063\u3068\u3082\u3089\u3057\u3044\u30d7\u30ed\u30bb\u30b9\u304c\u3042\u308a\u307e\u3059\u3002\u3053\u308c\u3089\u306e\u30a8\u30af\u30bd\u30bd\u30fc\u30e0\u306f\u9060\u304f\u307e\u3067\u79fb\u52d5\u3059\u308b\u3053\u3068\u304c\u3067\u304d\u307e\u3059\u3002\u80ba\u304b\u3089\u653e\u51fa\u3055\u308c\u3001\u8fd1\u304f\u306e\u4eba\u304c\u5438\u3044\u8fbc\u3080\u3053\u3068\u3082\u4e0d\u53ef\u80fd\u3067\u306f\u3042\u308a\u307e\u305b\u3093\u3002\u30a8\u30af\u30bd\u30bd\u30fc\u30e0\u3092\u542b\u3080\u7d30\u80de\u5916\u5c0f\u80de\u306f\u3001\u75f0\u3001\u7c98\u6db2\u3001\u4e0a\u76ae\u5185\u6db2\u3001\u6c17\u7ba1\u652f\u80ba\u80de\u6d17\u6d44\u6db2\u306b\u304a\u3044\u3066\u547c\u5438\u5668\u75be\u60a3\u3068\u95a2\u9023\u3057\u3066\u691c\u51fa\u3055\u308c\u3066\u3044\u307e\u3059\uff08Lucchetti et al., 2021\uff09\u3002<\/p>\n<\/blockquote>\n\n\n\n

\u300c\u3082\u3063\u3068\u3082\u3089\u3057\u3044\u30d7\u30ed\u30bb\u30b9\u300d\u304c\u3042\u308b\u3068\u8a00\u3044\u5207\u3063\u3066\u3044\u307e\u3059\u3002\u305d\u308c\u305e\u308c\u306e\u73fe\u8c61\u304c\u3042\u308b\u3068\u3057\u3066\u3001\u305d\u306e\u30d7\u30ed\u30bb\u30b9\u304c\u5b9f\u969b\u306b\u8d77\u3053\u308b\u306e\u304b\u3001\u60f3\u50cf\u306e\u4e2d\u3067\u3064\u306a\u3044\u3060\u3060\u3051\u306a\u306e\u304b\u306f\u308f\u304b\u3089\u306a\u3044\u3082\u306e\u306a\u306e\u3067\u3059\u304c\u3001\u65b0\u578b\u30b3\u30ed\u30ca\u30a6\u30a4\u30eb\u30b9\u306e\u30ef\u30af\u30c1\u30f3\u3092\u63a5\u7a2e\u3057\u305f\u30d2\u30c8\u306b\u5b9f\u969b\u306b\u8d77\u304d\u305f\u3068\u3044\u3046\u30c7\u30fc\u30bf\u306f\u660e\u8a18\u3055\u308c\u3066\u3044\u307e\u305b\u3093\u3002\u3042\u3068\u3001\u30d7\u30ea\u30aa\u30f3\u3068\u8a00\u3048\u3070\u30af\u30ed\u30a4\u30c4\u30d5\u30a7\u30eb\u30c8\u30fb\u30e4\u30b3\u30d6\u75c5\u3084\u72c2\u725b\u75c5\u3092\u5f15\u304d\u8d77\u3053\u3059\u3053\u3068\u3067\u77e5\u3089\u308c\u3066\u3044\u307e\u3059\u304c\u3001mRNA\u30ef\u30af\u30c1\u30f3\u306e\u526f\u53cd\u5fdc\u3084\u65b0\u578b\u30b3\u30ed\u30ca\u30a6\u30a4\u30eb\u30b9\u306e\u75c5\u614b\u306b\u95a2\u9023\u3057\u3066\u3044\u308b\u3068\u3044\u3046\u8a71\u306f\u805e\u3044\u305f\u3053\u3068\u304c\u3042\u308a\u307e\u305b\u3093\u3002<\/p>\n\n\n\n

\u79c1\u304c\u3053\u3053\u307e\u3067\u898b\u3066\u304d\u305f\u7bc4\u56f2\u3067\u306f\u3001Seneff\u6c0f\u306e\u6587\u732e\u306f\u3001\u81ea\u7136\u73fe\u8c61\u3084\u5b9f\u9a13\u74b0\u5883\u3067\u306e\u73fe\u8c61\u3092\u89b3\u5bdf\u3057\u3066\u3001\u305d\u306e\u89b3\u5bdf\u7d50\u679c\u3092\u89e3\u91c8\u3059\u308b\u3068\u3044\u3046\u79d1\u5b66\u7684\u306a\u30d7\u30ed\u30bb\u30b9\u306b\u57fa\u3065\u3044\u305f\u30ed\u30b8\u30c3\u30af\u306f\u8aad\u307f\u53d6\u308c\u306a\u3044\u6587\u66f8\u3067\u3042\u308b\u3053\u3068\u304c\u7406\u89e3\u3067\u304d\u307e\u3057\u305f\u3002<\/p>\n\n\n\n

References:<\/strong><\/p>\n\n\n\n

Hsieh, Y.-C., Wu, F.-T., Hsiung, C. A., Wu, H.-S., Chang, K.-Y., & Huang, Y.-C. (2014). Comparison of virus shedding after lived attenuated and pentavalent reassortant rotavirus vaccine. 32(10), 1199\u20131204. https:\/\/doi.org\/10.1016\/j.vaccine.2013.08.041<\/p>\n\n\n\n

Lucchetti, D., Santini, G., Perelli, L., Ricciardi-Tenore, C., Colella, F., Mores, N., Macis, G., Bush, A., Sgambato, A., & Montuschi, P. (2021). Detection and characterisation of extracellular vesicles in exhaled breath condensate and sputum of COPD and severe asthma patients<\/em>. 58<\/em>(2), 2003024. https:\/\/doi.org\/10.1183\/13993003.03024-2020<\/p>\n\n\n\n


Markkula, J., Hemming-Harlo, M., & Vesikari, T. (2020). Shedding of oral pentavalent bovine-human reassortant rotavirus vaccine indicates high uptake rate of vaccine and prominence of G-type G1. 38(6), 1378\u20131383. https:\/\/doi.org\/10.1016\/j.vaccine.2019.12.007<\/p>\n\n\n\n


Vos, A., Freuling, C., Ortmann, S., Kretzschmar, A., Mayer, D., Schliephake, A., & M\u00fcller, T. (2018). An assessment of shedding with the oral rabies virus vaccine strain SPBN GASGAS in target and non-target species. 36(6), 811\u2013817. https:\/\/doi.org\/10.1016\/j.vaccine.2017.12.076<\/p>\n\n\n\n


Yen, C., Jakob, K., Esona, M. D., Peckham, X., Rausch, J., Hull, J. J., Whittier, S., Gentsch, J. R., & LaRussa, P. (2011). Detection of fecal shedding of rotavirus vaccine in infants following their first dose of pentavalent rotavirus vaccine. 29(24), 4151\u20134155. https:\/\/doi.org\/10.1016\/j.vaccine.2011.03.074<\/p>\n","protected":false},"excerpt":{"rendered":"

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