{"id":1905,"date":"2019-02-03T22:05:14","date_gmt":"2019-02-03T13:05:14","guid":{"rendered":"https:\/\/plaza.umin.ac.jp\/~OIO\/?p=1905"},"modified":"2021-11-19T22:26:39","modified_gmt":"2021-11-19T13:26:39","slug":"self-controlled-case-series-sccs-3-2","status":"publish","type":"post","link":"https:\/\/plaza.umin.ac.jp\/~OIO\/?p=1905","title":{"rendered":"self-controlled case series (SCCS) – (3)"},"content":{"rendered":"

\u306f\u3058\u3081\u306b<\/h2>\n

Self-controlled case series (SCCS) \u306e\u89e3\u6790\u65b9\u6cd5\u3092\u8a66\u3057\u306f\u3058\u3081\u3066<\/a>\u3057\u3070\u3089\u304f\u6642\u9593\u304c\u7d4c\u904e\u3057\u307e\u3057\u305f\u3002\u305d\u306e\u9593\u306b\u3001\u3053\u306eSCCS\u3092\u8a08\u7b97\u3059\u308b\u305f\u3081\u306eR\u306e\u30d1\u30c3\u30b1\u30fc\u30b8\u304c\u958b\u767a\u3055\u308c\u3066\u3044\u307e\u3057\u3066\u3001\u4e00\u898b\u3057\u305f\u3068\u3053\u308d\u4fbf\u5229\u305d\u3046\u3067\u3059\u3002\u3068\u308a\u3042\u3048\u305a\u3001\u3054\u591a\u5206\u306b\u6f0f\u308c\u305a\u3001\u3053\u306e\u30d1\u30c3\u30b1\u30fc\u30b8\u3092\u5229\u7528\u3057\u3066\u3001\u904e\u53bb\u306b\u3084\u3063\u305f\u65b9\u6cd5<\/a>\u3084\u8ad6\u6587<\/a>1<\/sup><\/span>\u3068\u540c\u3058\u7d50\u679c\u304c\u5f97\u3089\u308c\u308b\u306e\u304b\u8a66\u3057\u3066\u307f\u307e\u3057\u305f\u3002<\/p>\n

\u307e\u305a\u306f\u30a4\u30f3\u30b9\u30c8\u30fc\u30eb<\/h2>\n
install("SCCS")<\/pre>\n
\u9069\u5207\u306a\u30b5\u30fc\u30d0\u30fc\u3092\u9078\u629e\u3057\u3066\u30a4\u30f3\u30b9\u30c8\u30fc\u30eb\u304c\u5b8c\u4e86\u3059\u308b\u306e\u3092\u5f85\u3061\u307e\u3059\u3002<\/p>\n
\u8aad\u307f\u8fbc\u307f\u307e\u3059<\/h2>\n
library("SCCS")<\/pre>\n
\u30aa\u30c3\u30af\u30b9\u30d5\u30a9\u30fc\u30c9\u4f2f\u7235\u306e\u30de\u30fc\u30c1<\/h2>\n
\u4ee5\u524dObservation Island\u3067\u8a66\u3057\u305f<\/a>oxford\u30c7\u30fc\u30bf\u304c\uff0c\u3053\u306e\u30d1\u30c3\u30b1\u30fc\u30b8\u3067\u306famdat\u3068\u3044\u3046\u540d\u524d\u3067\u542b\u307e\u308c\u3066\u3044\u307e\u3059\u3002\u3069\u3093\u306a\u5185\u5bb9\u304b\u78ba\u8a8d\u3057\u3066\u307f\u307e\u3059\u3002<\/p>\n
amdat\r\n   case sta end  am mmr\r\n1     1 366 730 398 458\r\n2     2 366 730 399 750\r\n3     3 366 730 413 392\r\n4     4 366 730 449 429\r\n5     5 366 730 455 433\r\n6     6 366 730 472 432\r\n7     7 366 730 474 395\r\n8     8 366 730 485 470\r\n9     9 366 730 524 496\r\n10   10 366 730 700 428\r\n<\/pre>\n
\u4ee5\u524d\u4f7f\u7528\u3057\u305foxford\u30c7\u30fc\u30bf\u306f\u6b21\u306e\u901a\u308a\u3067\u3059<\/h4>\n
\u826f\u304f\u4f3c\u3066\u3044\u308b\u3051\u3069\u5fae\u5999\u306b\u8abf\u6574\u304c\u5fc5\u8981\u305d\u3046\u3067\u3059<\/p>\n\n\n\n\n\n\n\n\n\n\n\n\n\n
indiv<\/td>\neventday<\/td>\nstart<\/td>\nend<\/td>\nexday<\/td>\n<\/tr>\n
1<\/td>\n398<\/td>\n365<\/td>\n730<\/td>\n458<\/td>\n<\/tr>\n
2<\/td>\n413<\/td>\n365<\/td>\n730<\/td>\n392<\/td>\n<\/tr>\n
3<\/td>\n449<\/td>\n365<\/td>\n730<\/td>\n429<\/td>\n<\/tr>\n
4<\/td>\n455<\/td>\n365<\/td>\n730<\/td>\n433<\/td>\n<\/tr>\n
5<\/td>\n472<\/td>\n365<\/td>\n730<\/td>\n432<\/td>\n<\/tr>\n
6<\/td>\n474<\/td>\n365<\/td>\n730<\/td>\n395<\/td>\n<\/tr>\n
7<\/td>\n485<\/td>\n365<\/td>\n730<\/td>\n470<\/td>\n<\/tr>\n
8<\/td>\n524<\/td>\n365<\/td>\n730<\/td>\n496<\/td>\n<\/tr>\n
9<\/td>\n700<\/td>\n365<\/td>\n730<\/td>\n428<\/td>\n<\/tr>\n
10<\/td>\n399<\/td>\n365<\/td>\n730<\/td>\n716<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n
\u89b3\u5bdf\u306e\u958b\u59cb\u65e5<\/h3>\n
\u524d\u56de\u8a66\u3057\u305foxford\u30c7\u30fc\u30bf\u3067\u306f\u958b\u59cb\u65e5\u304c365\u3067\u3057\u305f\u3002\u3053\u306e\u30d1\u30c3\u30b1\u30fc\u30b8\u306eamdat\u3067\u306f366\u306b\u3002\u3046\u308b\u3046\u5e74\u306b\u304b\u304b\u3063\u3066\u3057\u307e\u3063\u305f\u304b\u306a\uff1f\u306a\u3069\u3068\u601d\u3046\u306e\u3082\u826f\u3044\u306e\u3067\u3059\u304c\u3001\u3068\u308a\u3042\u3048\u305a\u540c\u3058\u30c7\u30fc\u30bf\u3067\u958b\u59cb\u3057\u305f\u3044\u306e\u3067\u3001\u8a66\u884c\u3059\u308b\u9593\u306f\u30d1\u30e9\u30e1\u30fc\u30bf\u3092\u6295\u5165\u3059\u308b\u969b\u306b\u3053\u306e\u90e8\u5206\u3092\u524d\u56de\u3068\u540c\u3058\u306b\u306a\u308b\u3088\u3046\u306b\u8abf\u6574\u3002\u5177\u4f53\u7684\u306b\u306f\u30b9\u30af\u30ea\u30d7\u30c8\u3067\u30d1\u30e9\u30e1\u30fc\u30bf\u3092\u4e0e\u3048\u308b\u969b\u306b\u3001<\/p>\n
astart=sta<\/p><\/blockquote>\n
\u3068\u4e0e\u3048\u308b\u3079\u304d\u3068\u3053\u308d\u3092<\/p>\n
astart=sta-1<\/p><\/blockquote>\n
\u306b\u3057\u3066\u8abf\u6574\u3057\u307e\u3057\u305f\u3002<\/p>\n
\u75c7\u4f8b\uff12\u306eMMR\u63a5\u7a2e\u65e5\u304c\u524d\u56de\u3068\u9055\u3046<\/h3>\n
\u524d\u56de\u8a66\u3057\u305foxford\u30c7\u30fc\u30bf\u3067\u306f\u75c7\u4f8b10\u306e\u63a5\u7a2e\u65e5\u306f716\u65e5\u76ee\u3060\u3063\u305f\u306e\u304c\u3001\u4eca\u56de\u30d1\u30c3\u30b1\u30fc\u30b8\u9644\u5c5e\u306eamdat\u3067\u306f\u540c\u3058\u75c7\u4f8b\u304c\u300c\u75c7\u4f8b\uff12\u300d\u306b\u306a\u3063\u3066\u3044\u3066\uff0c\u63a5\u7a2e\u65e5\u304c750\u65e5\u76ee\u306b\u306a\u3063\u3066\u3044\u307e\u3057\u305f\u3002\u3068\u308a\u3042\u3048\u305a\u3053\u3053\u3082\u3001\u524d\u56de\u306b\u5408\u308f\u305b\u3066\u304a\u304d\u305f\u3044\u306e\u3067<\/p>\n
amdat[2,5] <- 716<\/p><\/blockquote>\n
\u3068\u3084\u308a\u307e\u3059\u3002\u306a\u3093\u3060\u304b\u3001\u7d30\u304b\u3044\u8cea\u306e\u90e8\u5206\u306b\u9f5f\u9f6c\u304c\u6b8b\u3063\u3066\u3044\u308b\u306a\u3002<\/p>\n
\u30b9\u30af\u30ea\u30d7\u30c8<\/h5>\n
\u4e0a\u8a182\u70b9\u306e\u8abf\u6574\u3092\u542b\u3080\u30b9\u30af\u30ea\u30d7\u30c8\u306f\u6b21\u306e\u3088\u3046\u306b\u306a\u308a\u307e\u3059\u3002<\/p>\n
\r\n\r\nlibrary("SCCS")\r\n\r\namdat[2,5] <- 716\r\nam.mod2 <- standardsccs(event~mmr+age, indiv=case, astart=sta-1,\r\naend=end, aevent=am, adrug=mmr, aedrug=mmr+35,\r\nexpogrp=15, agegrp=547, data=amdat)\r\nam.mod2\r\n\r\n<\/pre>\n
\u5b9f\u884c\u7d50\u679c<\/h2>\n
\u89e3\u308a\u306b\u304f\u3044\u304b\u3082\u3057\u308c\u307e\u305b\u3093\u304c\u3001mmr\u306e\u30aa\u30c3\u30ba\u6bd4\u304c12.037 (95%CI, 3.00226, 48.259)\u3068\u306a\u308a\u307e\u3057\u305f\u3002<\/p>\n
\"\"<\/p>\n
 <\/p>\n
\u6b21\u306b\u793a\u3059\u306e\u304c\u8ad6\u6587\u3067\u63b2\u8f09\u3055\u308c\u305f\u7d50\u679c\u3067\u3059\u3002\u4eca\u56de\u306e\u96c6\u8a08\u7d50\u679c\u3068\u8ad6\u6587\u306e\u7d50\u679c\u3067\u3001\u5c0f\u6570\u70b9\u4ee5\u4e0b2\u6841\u304f\u3089\u3044\u307e\u3067\u306f\u4e00\u81f4\u3057\u3066\u3044\u307e\u3059\u3002\u8aa4\u5dee\u7bc4\u56f2\u3068\u8003\u3048\u3089\u308c\u307e\u3059\u306e\u3067\u3001\u4eca\u56de\u8a66\u3057\u305fR\u306eSCCS\u30d1\u30c3\u30b1\u30fc\u30b8\u304c\u601d\u3063\u305f\u3088\u3046\u306b\u6a5f\u80fd\u3059\u308b\u3053\u3068\u304c\u78ba\u8a8d\u3067\u304d\u307e\u3057\u305f\u3002\u6295\u5165\u3059\u308b\u524d\u306e\u30c7\u30fc\u30bf\u3055\u3048\u304d\u3061\u3093\u3068\u3057\u3066\u3044\u305f\u3089\u3001\u4f7f\u3048\u305d\u3046\u3060\u3068\u3044\u3046\u5370\u8c61\u3092\u6301\u3061\u307e\u3057\u305f\u3002<\/p>\n
\"\"<\/p>\n
 <\/p>\n
reference<\/h4>\n
\n
\n
\n
\n
1.<\/div>\n
Whitaker H, Farrington C, Spiessens B, Musonda P. Tutorial in biostatistics: the self-controlled case series method. Stat Med<\/i>. 2006;25(10):1768-1797. [PubMed<\/a>]<\/span><\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n","protected":false},"excerpt":{"rendered":"
\u306f\u3058\u3081\u306b Self-controlled case series (SCCS) \u306e\u89e3\u6790\u65b9\u6cd5\u3092\u8a66\u3057\u306f\u3058\u3081\u3066\u3057\u3070\u3089\u304f\u6642\u9593\u304c\u7d4c\u904e\u3057\u307e\u3057\u305f\u3002\u305d\u306e\u9593\u306b\u3001\u3053\u306eSCCS\u3092\u8a08\u7b97\u3059\u308b\u305f\u3081\u306eR\u306e\u30d1\u30c3\u30b1\u30fc\u30b8\u304c\u958b\u767a\u3055\u308c\u3066\u3044\u307e\u3057\u3066\u3001\u4e00\u898b\u3057\u305f\u3068\u3053\u308d…<\/p>\n","protected":false},"author":1,"featured_media":252,"comment_status":"open","ping_status":"open","sticky":true,"template":"","format":"standard","meta":{"_jetpack_memberships_contains_paid_content":false,"footnotes":""},"categories":[4],"tags":[],"class_list":["post-1905","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-science"],"jetpack_featured_media_url":"https:\/\/plaza.umin.ac.jp\/~OIO\/wp-content\/uploads\/2017\/09\/\u30c7\u30fc\u30bf\u306e\u30b0\u30e9\u30d5\u30a3\u30ab\u30eb\u306a\u8868\u793a.png","jetpack_shortlink":"https:\/\/wp.me\/p9b6zl-uJ","jetpack_sharing_enabled":true,"_links":{"self":[{"href":"https:\/\/plaza.umin.ac.jp\/~OIO\/index.php?rest_route=\/wp\/v2\/posts\/1905","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/plaza.umin.ac.jp\/~OIO\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/plaza.umin.ac.jp\/~OIO\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/plaza.umin.ac.jp\/~OIO\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/plaza.umin.ac.jp\/~OIO\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=1905"}],"version-history":[{"count":0,"href":"https:\/\/plaza.umin.ac.jp\/~OIO\/index.php?rest_route=\/wp\/v2\/posts\/1905\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/plaza.umin.ac.jp\/~OIO\/index.php?rest_route=\/wp\/v2\/media\/252"}],"wp:attachment":[{"href":"https:\/\/plaza.umin.ac.jp\/~OIO\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=1905"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/plaza.umin.ac.jp\/~OIO\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=1905"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/plaza.umin.ac.jp\/~OIO\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=1905"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}