{"id":674,"date":"2025-02-03T10:29:06","date_gmt":"2025-02-03T01:29:06","guid":{"rendered":"https:\/\/plaza.umin.ac.jp\/wormjp\/wordpress\/?page_id=674"},"modified":"2026-02-12T15:53:59","modified_gmt":"2026-02-12T06:53:59","slug":"about-2","status":"publish","type":"page","link":"https:\/\/plaza.umin.ac.jp\/wormjp\/wordpress\/about\/about-2\/","title":{"rendered":"\u7dda\u866b\u306e\u4f53\u306f\u3069\u306e\u3088\u3046\u306b\u3067\u304d\u308b\u306e\uff1f\uff08\u767a\u751f\uff09"},"content":{"rendered":"\n<div id=\"toc_container\" class=\"wp-block-group pada_30\"><div class=\"wp-block-group__inner-container is-layout-constrained wp-block-group-is-layout-constrained\">\n<h2 class=\"wp-block-heading\">\u76ee\u6b21<\/h2>\n\n\n\n<div class=\"wp-block-columns is-layout-flex wp-container-core-columns-is-layout-9d6595d7 wp-block-columns-is-layout-flex\">\n<div class=\"wp-block-column is-layout-flow wp-block-column-is-layout-flow\" style=\"flex-basis:48%\">\n<ul class=\"wp-block-list list_none\">\n<li class=\"has-medium-font-size\"><strong><a href=\"#section-1\">\u6e1b\u6570\u5206\u88c2\uff08\u751f\u6b96\u817a\u3067\u7cbe\u5b50\u3068\u5375\u5b50\u304c\u3067\u304d\u308b\u307e\u3067\uff09<\/a><\/strong><\/li>\n\n\n\n<li class=\"has-medium-font-size\"><strong><a href=\"#section-2\">\u53d7\u7cbe\u3000\uff5e\u751f\u547d\u8a95\u751f\u306e\u77ac\u9593\uff5e<\/a><\/strong><\/li>\n\n\n\n<li class=\"has-medium-font-size\"><strong><a href=\"#section-3\">\u7dda\u866b\u304c\u5375\u304b\u3089\u4f53\u306e\u5f62\u3092\u4f5c\u308b\u521d\u671f\u306e\u904e\u7a0b\u2015\u6d41\u308c\u3001\u56de\u8ee2\u3001\u3081\u308a\u8fbc\u307f\u304c\u9375\u3068\u306a\u308b\u30e1\u30ab\u30cb\u30ba\u30e0<\/a><\/strong><\/li>\n\n\n\n<li class=\"has-medium-font-size\"><strong><a href=\"#section-4\">\u7d30\u80de\u7cfb\u8b5c\uff08\u4f53\u7d30\u80de\u306e\u904b\u547d\u6c7a\u5b9a\uff09<\/a><\/strong><\/li>\n\n\n\n<li class=\"has-medium-font-size\"><strong><a href=\"#section-5\">\u5f62\u614b\u5f62\u6210\u30fb\u5668\u5b98\u5f62\u6210<\/a><\/strong><\/li>\n\n\n\n<li class=\"has-medium-font-size\"><strong><a href=\"#section-6\">\u30d7\u30ed\u30b0\u30e9\u30e0\u7d30\u80de\u6b7b\uff08\u30a2\u30dd\u30c8\u30fc\u30b7\u30b9\uff09<\/a><\/strong><\/li>\n<\/ul>\n<\/div>\n\n\n\n<div class=\"wp-block-column is-layout-flow wp-block-column-is-layout-flow\" style=\"flex-basis:53%\"><div class=\"wp-block-image\">\n<figure class=\"aligncenter size-large\"><img decoding=\"async\" width=\"1024\" height=\"710\" src=\"https:\/\/plaza.umin.ac.jp\/wormjp\/wordpress\/wp-content\/uploads\/2025\/06\/d6968d53f843c6bf097e0f7be1aa4cb4-1024x710.png\" alt=\"\" class=\"wp-image-1070\" srcset=\"https:\/\/plaza.umin.ac.jp\/wormjp\/wordpress\/wp-content\/uploads\/2025\/06\/d6968d53f843c6bf097e0f7be1aa4cb4-1024x710.png 1024w, https:\/\/plaza.umin.ac.jp\/wormjp\/wordpress\/wp-content\/uploads\/2025\/06\/d6968d53f843c6bf097e0f7be1aa4cb4-300x208.png 300w, https:\/\/plaza.umin.ac.jp\/wormjp\/wordpress\/wp-content\/uploads\/2025\/06\/d6968d53f843c6bf097e0f7be1aa4cb4-768x533.png 768w, https:\/\/plaza.umin.ac.jp\/wormjp\/wordpress\/wp-content\/uploads\/2025\/06\/d6968d53f843c6bf097e0f7be1aa4cb4-670x465.png 670w, https:\/\/plaza.umin.ac.jp\/wormjp\/wordpress\/wp-content\/uploads\/2025\/06\/d6968d53f843c6bf097e0f7be1aa4cb4.png 1103w\" sizes=\"(max-width: 1024px) 100vw, 1024px\" \/><\/figure>\n<\/div>\n\n\n<p class=\"has-text-align-right\">Illustrated by Hiroko Uchida&nbsp;<\/p>\n<\/div>\n<\/div>\n<\/div><\/div>\n\n\n\n<div class=\"wp-block-group\" style=\"font-size:1.2em\"><div class=\"wp-block-group__inner-container is-layout-constrained wp-block-group-is-layout-constrained\">\n<p>\u79c1\u305f\u3061\u30d2\u30c8\u3068\u540c\u3058\u3088\u3046\u306b\u3001\u7dda\u866b\u3082\u305f\u3063\u305f\u4e00\u3064\u306e\u7d30\u80de\u3067\u3042\u308b\u53d7\u7cbe\u5375\u304c\u5206\u88c2\u3092\u7e70\u308a\u8fd4\u3057\u3001\u591a\u6570\u306e\u7d30\u80de\u304b\u3089\u306a\u308b\u4f53\u304c\u3067\u304d\u3042\u304c\u308a\u307e\u3059\u3002\u7dda\u866b\u306f\u4f53\u304c\u900f\u660e\u306a\u305f\u3081\u3001\u4f53\u304c\u3067\u304d\u3042\u304c\u308b\u904e\u7a0b\u3092\u9855\u5fae\u93e1\u3067\u8a73\u7d30\u306b\u89b3\u5bdf\u3067\u304d\u307e\u3059\u3002\u53d7\u7cbe\u5f8c\u305f\u3063\u305f9\u6642\u9593\u3067\u5b75\u5316\u3057\u3001\u305d\u306e\u5f8c\u3001\u308f\u305a\u304b\uff13\u65e5\u9593\u3067\u6210\u866b\u306b\u307e\u3067\u6210\u9577\u3057\u307e\u3059\u3002\u3055\u3089\u306b\u306f\u3001\u7d30\u80de\u7cfb\u8b5c\uff08\u7d30\u80de\u5206\u88c2\u306e\u9806\u756a\u3084\u5206\u88c2\u3057\u305f\u7d30\u80de\u304c\u3069\u306e\u5668\u5b98\u3092\u5f62\u6210\u3059\u308b\u304b\u3068\u3044\u3046\u7d30\u80de\u904b\u547d\uff09\u304c\u3042\u3089\u304b\u3058\u3081\u6c7a\u307e\u3063\u3066\u3044\u308b\u3068\u3044\u3046\u7279\u5fb4\u3082\u3042\u308a\u3001\u4f53\u304c\u3067\u304d\u3042\u304c\u308b\u904e\u7a0b\u3092\u7814\u7a76\u3059\u308b\u306e\u306b\u3046\u3063\u3066\u3064\u3051\u306e\u751f\u304d\u7269\u3067\u3059\u3002\u5b9f\u969b\u306b\u3001\u4f53\u304c\u3067\u304d\u3042\u304c\u308b\u3055\u307e\u3056\u307e\u306a\u4ed5\u7d44\u307f\u304c\u7dda\u866b\u3092\u4f7f\u3063\u3066\u660e\u3089\u304b\u306b\u3055\u308c\u3066\u304d\u3066\u3001\u305d\u306e\u591a\u304f\u306f\u30d2\u30c8\u306b\u3082\u5171\u901a\u3059\u308b\u3068\u8003\u3048\u3089\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<p><strong>\u76e3\u4fee\u8005<\/strong><br>\u6728\u6751\u3000\u6681\u3000<br>\u6771\u4eac\u5927\u5b66\u5927\u5b66\u9662\u535a\u58eb\u8ab2\u7a0b\u4fee\u4e86\u3002\u73fe\u5728\u3001\u56fd\u7acb\u907a\u4f1d\u5b66\u7814\u7a76\u6240\u6559\u6388\u3068\u3057\u3066\u300c\u7d30\u80de\u304c\u5efa\u7bc9\u3055\u308c\u308b\u4ed5\u7d44\u307f\u300d\u306e\u7814\u7a76\u3092\u62c5\u5f53\u3057\u3066\u3044\u308b\u3002<\/p>\n\n\n\n<p><strong>\u7814\u7a76\u5ba4HP<\/strong><br><a href=\"https:\/\/www.nig.ac.jp\/nig\/ja\/research\/organization-top\/laboratories\/kimura\" target=\"_blank\" rel=\"noreferrer noopener\">https:\/\/www.nig.ac.jp\/nig\/ja\/research\/organization-top\/laboratories\/kimura<\/a><\/p>\n\n\n\n<p class=\"has-text-align-right has-small-font-size\">\u00a92026 \u866b\u306e\u96c6\u3044\uff08\u7dda\u866b\u7814\u7a76\u8005\u30b3\u30df\u30e5\u30cb\u30c6\u30a3\uff09\u300c\u5e8f\u8ad6\u300d<a href=\"https:\/\/creativecommons.org\/licenses\/by\/4.0\/\">CC BY<\/a><\/p>\n<\/div><\/div>\n\n\n\n<div style=\"height:50px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<section id=\"section-1\" class=\"wp-block-group\"><div class=\"wp-block-group__inner-container is-layout-constrained wp-block-group-is-layout-constrained\">\n<h3 class=\"wp-block-heading\">1.\u3000\u6e1b\u6570\u5206\u88c2\uff08\u751f\u6b96\u817a\u3067\u7cbe\u5b50\u3068\u5375\u5b50\u304c\u3067\u304d\u308b\u307e\u3067\uff09<\/h3>\n\n\n\n<h4 class=\"wp-block-heading\">\u7cbe\u5b50\u3068\u5375\u5b50\u3092\u4f5c\u308a\u51fa\u3059\u7279\u5225\u306a\u7d30\u80de\u5206\u88c2\uff1a\u6e1b\u6570\u5206\u88c2<\/h4>\n\n\n\n<p>\u3000\u6e1b\u6570\u5206\u88c2\u306f\u3001\u7cbe\u5b50\u3001\u5375\u5b50\u306a\u3069\u306e\u751f\u6b96\u7d30\u80de\u3092\u751f\u307f\u51fa\u3059\u7279\u5225\u306a\u7d30\u80de\u5206\u88c2\u3067\u3059\u3002\u7d30\u80de\u304c\u6b63\u5e38\u306b\u50cd\u304f\u305f\u3081\u306b\u306f\u3001\u9069\u5207\u306a\u6570\u306e\u67d3\u8272\u4f53\u3092\u6301\u3063\u3066\u3044\u308b\u3053\u3068\u304c\u91cd\u8981\u3067\u3042\u308a\u3001\u4f8b\u3048\u3070\u30d2\u30c8\u306e\u5834\u5408\u306f\u3001\u6bcd\u65b9\u304b\u308923\u672c\u3001\u7236\u65b9\u304b\u308923\u672c\u306e\u67d3\u8272\u4f53\u3092\u53d7\u3051\u7d99\u3050\u3053\u3068\u3067\u300146\u672c\u306e\u67d3\u8272\u4f53\u3092\u6301\u3063\u3066\u3044\u307e\u3059\u3002\u67d3\u8272\u4f53\u306e\u6570\u304c\u591a\u3059\u304e\u3066\u3082\u5c11\u306a\u3059\u304e\u3066\u3082\u7d30\u80de\u306e\u50cd\u304d\u306b\u7570\u5e38\u3092\u304d\u305f\u3059\u305f\u3081\u3001\u6b63\u3057\u3044\u6570\u3068\u7d44\u307f\u5408\u308f\u305b\uff081\u756a\u67d3\u8272\u4f53\u304b\u308922\u756a\u67d3\u8272\u4f53\u304b\u3089\u306a\u308b\u5e38\u67d3\u8272\u4f53\u3068\u3001\u6027\u67d3\u8272\u4f53\uff09\u306e\u67d3\u8272\u4f53\u3092\u89aa\u304b\u3089\u53d7\u3051\u7d99\u3050\u3053\u3068\u304c\u751f\u7269\u306b\u3068\u3063\u3066\u91cd\u8981\u3067\u3059\u3002<br>\u3000\u6e1b\u6570\u5206\u88c2\u3067\u306f\u3001\u5143\u3068\u306a\u308b\u7d30\u80de\uff08\u30d2\u30c8\u306e\u5834\u5408\u306f46\u672c\u306e\u67d3\u8272\u4f53\u3092\u6301\u3064\u7d30\u80de\uff09\u304b\u3089\u3001\u67d3\u8272\u4f53\u3092\u6b63\u78ba\u306b\u534a\u6570\u5316\u3057\u305f\u751f\u6b96\u7d30\u80de\uff08\u30d2\u30c8\u306e\u5834\u5408\u306f23\u672c\u306e\u67d3\u8272\u4f53\u3092\u6301\u3064\u7cbe\u5b50\u30fb\u5375\u5b50\uff09\u3092\u751f\u307f\u51fa\u3057\u307e\u3059\u3002\u3053\u306e\u7cbe\u5b50\u3068\u5375\u5b50\u304c\u53d7\u7cbe\u306b\u3088\u308a\u5408\u4f53\u3059\u308b\u3053\u3068\u3067\u3001\u30d2\u30c8\u306e\u5834\u5408\u306f\u518d\u307346\u672c\u306e\u67d3\u8272\u4f53\u3092\u6301\u30641\u7d30\u80de\u304c\u8a95\u751f\u3057\u3001\u305d\u3053\u304b\u3089\u5b50\u5b6b\u3068\u306a\u308b\u500b\u4f53\u304c\u8a95\u751f\u3057\u307e\u3059\u3002\u6e1b\u6570\u5206\u88c2\u306b\u304a\u3051\u308b\u30a8\u30e9\u30fc\u306f\u3001\u4eba\u9593\u306e\u5834\u5408\u3001\u7570\u5e38\u306a\u7cbe\u5b50\u3084\u5375\u5b50\u306e\u7523\u51fa\u3001\u305d\u3057\u3066\u4e0d\u598a\u3001\u6d41\u7523\u3084\u67d3\u8272\u4f53\u7570\u5e38\u75c7\u306a\u3069\u306b\u3064\u306a\u304c\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<h4 class=\"wp-block-heading\">\u6e1b\u6570\u5206\u88c2\u306e\u3057\u304f\u307f<\/h4>\n\n\n\n<p>\u3000\u3067\u306f\u6e1b\u6570\u5206\u88c2\u306b\u304a\u3044\u3066\u3001\u67d3\u8272\u4f53\u306f\u3069\u306e\u3088\u3046\u306b\u534a\u6570\u5316\u3055\u308c\u3066\u3044\u308b\u306e\u3067\u3057\u3087\u3046\u304b\uff1f<br>\u4f53\u7d30\u80de\u5206\u88c2\u3067\u306f\u3001\u305d\u308c\u305e\u308c\u306e\u67d3\u8272\u4f53\u304c\u3001\u8907\u88fd\u3055\u308c\u3001\u59c9\u59b9\u67d3\u8272\u4f53\u304c\u5206\u96e2\u3055\u308c\u308b\u3060\u3051\u3067\u3059\u3002\u4e00\u65b9\u3001\u6e1b\u6570\u5206\u88c2\u3067\u306f\u3001\u666e\u6bb5\u306f\u72ec\u7acb\u306b\u5b58\u5728\u3057\u3066\u3044\u308b\u76f8\u540c\u67d3\u8272\u4f53\uff08\u4f8b\u3048\u3070\u3001\u6bcd\u65b9\u7b2c\u4e00\u67d3\u8272\u4f53\u3068\u3001\u7236\u65b9\u7b2c\u4e00\u67d3\u8272\u4f53\uff09\u304c\u3001\u8907\u88fd\u3055\u308c\u305f\u3042\u3068\u306b\u30012\u56de\u9023\u7d9a\u3057\u3066\u5206\u96e2\u3055\u308c\u308b\u3053\u3068\u306b\u3088\u3063\u3066\u534a\u6570\u5316\u3055\u308c\u307e\u3059\u3002\u3053\u308c\u306f\u6e1b\u6570\u7b2c\u4e00\u5206\u88c2\u3001\u7b2c\u4e8c\u5206\u88c2\u3068\u547c\u3070\u308c\u307e\u3059(\u56f31)\u3002\u3053\u306e\u305f\u3081\u751f\u6b96\u7d30\u80de\u306f\u3001\u7b2c\u4e00\u5206\u88c2\u306b\u304a\u3044\u3066\u5206\u96e2\u3059\u308b\u67d3\u8272\u4f53\u306e\u9818\u57df\u3001\u7b2c\u4e8c\u5206\u88c2\u306b\u304a\u3044\u3066\u5206\u96e2\u3059\u308b\u9818\u57df\u3092\u3001\u5206\u88c2\u524d\u306b\u3042\u3089\u304b\u3058\u3081\u6c7a\u3081\u3066\u304a\u304b\u306a\u3051\u308c\u3070\u306a\u308a\u307e\u305b\u3093\u3002<br>\u3000\u79c1\u305f\u3061\u30d2\u30c8\u3067\u306f\u3001\u67d3\u8272\u4f53\u4e0a\u306e\u30bb\u30f3\u30c8\u30ed\u30e1\u30a2\u3068\u547c\u3070\u308c\u308b\u7279\u5b9a\u306eDNA\u9818\u57df\u3092\u7528\u3044\u3066\u3001\u6e1b\u6570\u5206\u88c2\u306b\u304a\u3051\u308b\u67d3\u8272\u4f53\u5206\u96e2\u9762\u3092\u6c7a\u3081\u3066\u304a\u308a\u3001\u7b2c\u4e00\u5206\u88c2\u3067\u306f\u3001\u30bb\u30f3\u30c8\u30ed\u30e1\u30a2\u4ee5\u5916\u306e\u9818\u57df\u306b\u304a\u3044\u3066\u67d3\u8272\u4f53\u3092\u5206\u96e2\u3057\u3001\u7b2c\u4e8c\u5206\u88c2\u3067\u306f\u3001\u30bb\u30f3\u30c8\u30ed\u30e1\u30a2\u9818\u57df\u306b\u304a\u3044\u3066\u67d3\u8272\u4f53\u3092\u5206\u96e2\u3059\u308b\u3053\u3068\u304c\u77e5\u3089\u308c\u3066\u3044\u307e\u3059\u3002<br>\u3000\u4e00\u65b9\u3001\u7dda\u866b\u3084\u4e00\u90e8\u306e\u690d\u7269\u3084\u6606\u866b\u3067\u306f\u3001\u3053\u306e\u30bb\u30f3\u30c8\u30ed\u30e1\u30a2\u69d8\u306e\u50cd\u304d\u3092\u3059\u308bDNA\u9818\u57df\u304c\u67d3\u8272\u4f53\u5168\u4f53\u306b\u5e83\u304c\u3063\u3066\u304a\u308a\u3001\u30d2\u30c8\u3068\u540c\u3058\u3088\u3046\u306b\u3001\u30bb\u30f3\u30c8\u30ed\u30e1\u30a2\u3068\u305d\u308c\u4ee5\u5916\u3001\u306e2\u3064\u306e\u9818\u57df\u306b\u67d3\u8272\u4f53\u3092\u5206\u3051\u308b\u3053\u3068\u304c\u3067\u304d\u307e\u305b\u3093\u3002\u3067\u306f\u3001\u7dda\u866b\u3067\u306f\u3001\u3069\u306e\u3088\u3046\u306b\u67d3\u8272\u4f53\u30922\u3064\u306e\u9818\u57df\u306b\u5206\u3051\u3066\u3044\u308b\u306e\u3067\u3057\u3087\u3046\u304b\uff1f<\/p>\n\n\n<div class=\"wp-block-image\">\n<figure class=\"aligncenter size-full is-resized\"><img decoding=\"async\" width=\"3199\" height=\"1478\" src=\"https:\/\/plaza.umin.ac.jp\/wormjp\/wordpress\/wp-content\/uploads\/2025\/01\/2-1_01.png\" alt=\"\" class=\"wp-image-381\" style=\"width:800px\" srcset=\"https:\/\/plaza.umin.ac.jp\/wormjp\/wordpress\/wp-content\/uploads\/2025\/01\/2-1_01.png 3199w, https:\/\/plaza.umin.ac.jp\/wormjp\/wordpress\/wp-content\/uploads\/2025\/01\/2-1_01-300x139.png 300w, https:\/\/plaza.umin.ac.jp\/wormjp\/wordpress\/wp-content\/uploads\/2025\/01\/2-1_01-1024x473.png 1024w, https:\/\/plaza.umin.ac.jp\/wormjp\/wordpress\/wp-content\/uploads\/2025\/01\/2-1_01-768x355.png 768w, https:\/\/plaza.umin.ac.jp\/wormjp\/wordpress\/wp-content\/uploads\/2025\/01\/2-1_01-1536x710.png 1536w, https:\/\/plaza.umin.ac.jp\/wormjp\/wordpress\/wp-content\/uploads\/2025\/01\/2-1_01-2048x946.png 2048w, https:\/\/plaza.umin.ac.jp\/wormjp\/wordpress\/wp-content\/uploads\/2025\/01\/2-1_01-670x310.png 670w\" sizes=\"(max-width: 3199px) 100vw, 3199px\" \/><\/figure>\n<\/div>\n\n\n<h4 class=\"wp-block-heading\">\u9577\u3055\u3092\u6bd4\u3079\u308b\u3053\u3068\u3067\u67d3\u8272\u4f53\u3092\u5206\u96e2\u3059\u308b\u7dda\u866b\u306e\u6e1b\u6570\u5206\u88c2<\/h4>\n\n\n\n<p>\u3000\u6e1b\u6570\u5206\u88c2\u3067\u306f\u3001\u6e1b\u6570\u5206\u88c2\u524d\u671f\u3068\u547c\u3070\u308c\u308b\u6642\u671f\u306b\u3001\u6bcd\u65b9\u304b\u3089\u53d7\u3051\u7d99\u3044\u3060\u67d3\u8272\u4f53\u3068\u3001\u7236\u65b9\u304b\u3089\u53d7\u3051\u7d99\u3044\u3060\u67d3\u8272\u4f53\u304c\u30da\u30a2\u306b\u306a\u308a\u3001\u3055\u3089\u306b\u6bcd\u65b9\u3068\u7236\u65b9\u306e\u67d3\u8272\u4f53\u3092\u4e00\u90e8\u5207\u65ad\u3057\u3066\u3001\u3064\u306a\u304e\u304b\u3048\u3089\u308c\u308b\u3053\u3068\u3067\u3001\u6bcd\u7531\u6765\u3068\u7236\u7531\u6765\u306e\u907a\u4f1d\u5b50\u306e\u7d44\u307f\u5408\u308f\u305b\u304c\u30b7\u30e3\u30c3\u30d5\u30eb\u3055\u308c\u307e\u3059\u3002\u3053\u306e\u67d3\u8272\u4f53\u304c\u3064\u306a\u304e\u5909\u3048\u3089\u308c\u305f\u90e8\u5206\u306f\u201c\u30ad\u30a2\u30ba\u30de\u201d\u3068\u547c\u3070\u308c\u3001\u7dda\u866b\u3067\u306f\u3001\u76f8\u540c\u67d3\u8272\u4f53\u306e\u30da\u30a2\u306b\u3064\u304d\u3001\u5fc5\u305a\uff11\u3064\u306e\u30ad\u30a2\u30ba\u30de\u304c\u4f5c\u3089\u308c\u307e\u3059\u3002<br>\u3000\u5b9f\u306f\u3001\u7dda\u866b\u306e\u751f\u6b96\u7d30\u80de\u306f\u3001\u30ad\u30a2\u30ba\u30de\u304b\u3089\u67d3\u8272\u4f53\u672b\u7aef\u307e\u3067\u306e\u8ddd\u96e2\u3092\u6bd4\u3079\u308b\u3053\u3068\u3067\u3001\u67d3\u8272\u4f53\u672b\u7aef\u307e\u3067\u77ed\u3044\u65b9\u3068\u3001\u9577\u3044\u65b9\u3001\u3068\u3044\u3046\u5206\u3051\u65b9\u3067\u67d3\u8272\u4f53\u3092\uff12\u3064\u306e\u9818\u57df\u306b\u5206\u3051\u308b\u3053\u3068\u304c\u77e5\u3089\u308c\u3066\u3044\u307e\u3059\uff08\u56f32\uff09\u3002<br>\u3000\u6e1b\u6570\u7b2c\u4e00\u5206\u88c2\u3067\u306f\u3001\u77ed\u3044\u65b9\u306e\u67d3\u8272\u4f53\u9818\u57df\u306b\u304a\u3044\u3066\u67d3\u8272\u4f53\u304c\u5206\u96e2\u3055\u308c\u3001\u7b2c\u4e8c\u5206\u88c2\u3067\u306f\u9577\u3044\u65b9\u306e\u67d3\u8272\u4f53\u9818\u57df\u306b\u304a\u3044\u3066\u5206\u96e2\u3055\u308c\u307e\u3059\u3002\u30ad\u30a2\u30ba\u30de\u306f\u3044\u3064\u3082\u6c7a\u307e\u3063\u305f\u5834\u6240\u306b\u4f5c\u3089\u308c\u308b\u306e\u3067\u306f\u306a\u304f\u3001\u67d3\u8272\u4f53\u4e0a\u306e\u8272\u3005\u306a\u5834\u6240\u306b\u4f5c\u3089\u308c\u308b\u305f\u3081\u3001\u7dda\u866b\u306e\u7d30\u80de\u306f\u3001\u30ad\u30a2\u30ba\u30de\u304c\u4f5c\u3089\u308c\u305f\u5f8c\u306b\u3001\u67d3\u8272\u4f53\u306e\u3069\u3061\u3089\u5074\u304c\u77ed\u304f\u3066\u3001\u3069\u3061\u3089\u5074\u304c\u9577\u3044\u304b\u306a\uff1f\u3068\u3044\u3046\u3053\u3068\u3092\u3001\u5b9a\u898f\u3082\u4f7f\u308f\u305a\u3001\u76ee\u3067\u898b\u308b\u3053\u3068\u3082\u306a\u304f\u3001\u691c\u51fa\u3067\u304d\u3066\u3044\u308b\u3068\u3044\u3046\u3053\u3068\u304c\u3001\u3053\u306e\u73fe\u8c61\u304b\u3089\u308f\u304b\u308a\u307e\u3059\u3002<br>\u3000\u7d30\u80de\u306f\u3001\u751f\u4f53\u5206\u5b50\u306e\u69d8\u3005\u306a\u7269\u7406\u5316\u5b66\u7684\u6027\u8cea\u3092\u99c6\u4f7f\u3057\u3066\u3001\u7d30\u80de\u5185\u306e\u5668\u5b98\u3084\u8907\u5408\u4f53\u306e\u30b5\u30a4\u30ba\u3092\u691c\u51fa\u3057\u305f\u308a\u3001\u8abf\u7bc0\u3067\u304d\u308b\u3053\u3068\u304c\u77e5\u3089\u308c\u3066\u3044\u307e\u3059\u304c\u3001\u5b9a\u898f\u304c\u306a\u304f\u3066\u3082\u30012\u3064\u306e\u3082\u306e\u306e\u9577\u3055\u3092\u6bd4\u3079\u308b\u3053\u3068\u3060\u3063\u3066\u3067\u304d\u308b\uff01\u3068\u3044\u3046\u3053\u3068\u3092\u3001\u7dda\u866b\u306e\u7d30\u80de\u306f\u6559\u3048\u3066\u304f\u308c\u307e\u3059\u3002\u3000<\/p>\n\n\n<div class=\"wp-block-image\">\n<figure class=\"aligncenter size-full is-resized\"><img decoding=\"async\" width=\"3199\" height=\"978\" src=\"https:\/\/plaza.umin.ac.jp\/wormjp\/wordpress\/wp-content\/uploads\/2025\/01\/2-1_02.png\" alt=\"\" class=\"wp-image-380\" style=\"width:800px\" srcset=\"https:\/\/plaza.umin.ac.jp\/wormjp\/wordpress\/wp-content\/uploads\/2025\/01\/2-1_02.png 3199w, https:\/\/plaza.umin.ac.jp\/wormjp\/wordpress\/wp-content\/uploads\/2025\/01\/2-1_02-300x92.png 300w, https:\/\/plaza.umin.ac.jp\/wormjp\/wordpress\/wp-content\/uploads\/2025\/01\/2-1_02-1024x313.png 1024w, https:\/\/plaza.umin.ac.jp\/wormjp\/wordpress\/wp-content\/uploads\/2025\/01\/2-1_02-768x235.png 768w, https:\/\/plaza.umin.ac.jp\/wormjp\/wordpress\/wp-content\/uploads\/2025\/01\/2-1_02-1536x470.png 1536w, https:\/\/plaza.umin.ac.jp\/wormjp\/wordpress\/wp-content\/uploads\/2025\/01\/2-1_02-2048x626.png 2048w, https:\/\/plaza.umin.ac.jp\/wormjp\/wordpress\/wp-content\/uploads\/2025\/01\/2-1_02-670x205.png 670w\" sizes=\"(max-width: 3199px) 100vw, 3199px\" \/><\/figure>\n<\/div>\n\n\n<p><strong>\u53c2\u8003\u8cc7\u6599<\/strong><br>1) Hillers K.J., Jantsch V., Martinez-Perez E., Yanowitz J.L. Meiosis. (May 4, 2017),&nbsp; <em>WormBook<\/em>, ed. The&nbsp;<em>C. elegans<\/em>&nbsp;Research Community, doi\/10.1895\/wormbook.1.178.1,&nbsp;<a href=\"http:\/\/www.wormbook.org\/\">http:\/\/www.wormbook.org<\/a>.<\/p>\n\n\n\n<p><strong>\u76e3\u4fee\u8005<\/strong><br>\u30ab\u30fc\u30eb\u30c8\u30f3 \u30d4\u30fc\u30bf\u30fc<br>\u30a2\u30e1\u30ea\u30ab\u5408\u8846\u56fd\u3001\u30b7\u30a2\u30c8\u30eb\u751f\u307e\u308c\u3002\u30ab\u30ea\u30d5\u30a9\u30eb\u30cb\u30a2\u5927\u5b66\u30d0\u30fc\u30af\u30ec\u30fc\u6821\u535a\u58eb\u8ab2\u7a0b\u4fee\u4e86\u3002\u73fe\u5728\u3001\u4eac\u90fd\u5927\u5b66\u3001\u5927\u5b66\u9662\u751f\u547d\u79d1\u5b66\u7814\u7a76\u79d1\u306e\u51c6\u6559\u6388\u3068\u3057\u3066\u6e1b\u6570\u5206\u88c2\u306b\u95a2\u3059\u308b\u7814\u7a76\u3092\u884c\u306a\u3063\u3066\u3044\u308b\u3002\u81ea\u8eab\u304c\u62c5\u5f53\u3059\u308b\u7dda\u866b\u306e\u5b9f\u7fd2\u6388\u696d\u3067\u306f\u3001\u5b66\u751f\u305f\u3061\u3068\u69d8\u3005\u306a\u5834\u6240\u304b\u3089\u91ce\u751f\u306e\u7dda\u866b\u682a\u3092\u63a1\u96c6\u3001\u540c\u5b9a\u3057\u3066\u304a\u308a\u3001\u3044\u3064\u304b\u65b0\u7a2e\u306e\u7dda\u866b\u3092\u767a\u898b\u3059\u308b\u3053\u3068\u3092\u76ee\u6307\u3057\u3066\u3044\u308b\u3002<br><br>\u4f50\u85e4\u3000\u7dbe\u3000<br>\u65e5\u672c\u3001\u5927\u962a\u751f\u307e\u308c\u3002\u30ab\u30ea\u30d5\u30a9\u30eb\u30cb\u30a2\u5927\u5b66\u30d0\u30fc\u30af\u30ec\u30fc\u6821\u535a\u58eb\u8ab2\u7a0b\u4fee\u4e86\u3002\u73fe\u5728\u3001\u4eac\u90fd\u5927\u5b66\u3001\u5927\u5b66\u9662\u751f\u547d\u79d1\u5b66\u7814\u7a76\u79d1\u30ab\u30fc\u30eb\u30c8\u30f3\u7814\u7a76\u5ba4\u306e\u535a\u58eb\u7814\u7a76\u54e1\u3068\u3057\u3066\u6e1b\u6570\u5206\u88c2\u306b\u95a2\u3059\u308b\u7814\u7a76\u3092\u884c\u306a\u3063\u3066\u3044\u308b\u3002<\/p>\n\n\n\n<p><strong>\u7814\u7a76\u5ba4HP<\/strong><br><a href=\"https:\/\/www.carltonlab.org\/\">https:\/\/www.carltonlab.org\/<\/a><\/p>\n\n\n\n<p class=\"has-text-align-right has-small-font-size\">\u00a92026 \u866b\u306e\u96c6\u3044\uff08\u7dda\u866b\u7814\u7a76\u8005\u30b3\u30df\u30e5\u30cb\u30c6\u30a3\uff09\u300c1.\u3000\u6e1b\u6570\u5206\u88c2\uff08\u751f\u6b96\u817a\u3067\u7cbe\u5b50\u3068\u5375\u5b50\u304c\u3067\u304d\u308b\u307e\u3067\uff09\u300d<a href=\"https:\/\/creativecommons.org\/licenses\/by\/4.0\/\">CC BY<\/a><\/p>\n\n\n\n<p class=\"has-text-align-right\"><a href=\"#toc_container\" data-type=\"internal\" data-id=\"#toc_container\">\u76ee\u6b21\u30da\u30fc\u30b8\u3078\u2191<\/a><\/p>\n\n\n\n<div style=\"height:20px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n<\/div><\/section>\n\n\n\n<section id=\"section-2\" class=\"wp-block-group\"><div class=\"wp-block-group__inner-container is-layout-constrained wp-block-group-is-layout-constrained\">\n<h3 class=\"wp-block-heading\">2.\u3000\u53d7\u7cbe\u3000\uff5e\u751f\u547d\u8a95\u751f\u306e\u77ac\u9593\uff5e<\/h3>\n\n\n\n<h4 class=\"wp-block-heading\">\u3069\u3046\u3084\u3063\u3066\u7dda\u866b\u306e\u5b50\u4f9b\u304c\u3067\u304d\u308b\u306e\u304b\uff1f<\/h4>\n\n\n\n<p>\u3000\u6027\u3092\u3082\u3064\u751f\u7269\u306b\u3068\u3063\u3066\u3001\u53d7\u7cbe\u3068\u306f\u751f\u547d\u8a95\u751f\u306e\u77ac\u9593\u3067\u3059\u3002\u89aa\u7531\u6765\u306e\u5375\u3068\u7cbe\u5b50\u304c\u878d\u5408\u3057\u3066\u53d7\u7cbe\u5375\u3068\u306a\u308a\u3001\u3053\u306e\u305f\u3063\u305f\u3072\u3068\u3064\u306e\u7d30\u80de\u304c\u5206\u88c2\u3092\u7e70\u308a\u8fd4\u3059\u3053\u3068\u3067\u52d5\u7269\u306e\u304b\u3089\u3060\u304c\u5f62\u3065\u304f\u3089\u308c\u3066\u3044\u304d\u307e\u3059\u3002\u5927\u4eba\u306b\u306a\u308c\u3070\u3001\u307e\u305f\u5375\u3084\u7cbe\u5b50\u3092\u3064\u304f\u308a\u3001\u305d\u306e\u4e2d\u306b\u542b\u307e\u308c\u308b\u907a\u4f1d\u5b50\u304c\u6b21\u306e\u4e16\u4ee3\u3078\u3068\u53d7\u3051\u7d99\u304c\u308c\u3066\u3044\u304d\u307e\u3059\u3002\u3053\u306e\u3088\u3046\u306b\u53d7\u7cbe\u306f\u751f\u547d\u3092\u3064\u306a\u3050\u3068\u3066\u3082\u795e\u79d8\u7684\u306a\u73fe\u8c61\u3067\u3059\u3002<br>\u3000\u7dda\u866b<em>C. elegans<\/em>\u306b\u306f\u300c\u96cc\u96c4\u540c\u4f53\u300d\u3068\u300c\u96c4\u300d\u3068\u3044\u3046\uff12\u3064\u306e\u6027\u5225\u304c\u3042\u308a\u307e\u3059\u3002\u96cc\u96c4\u540c\u4f53\u306f\u81ea\u5206\u81ea\u8eab\u3067\u5375\u3068\u7cbe\u5b50\u306e\u4e21\u65b9\u3092\u4f5c\u308a\u3001\u305d\u308c\u3089\u304c\u53d7\u7cbe\u3057\u3066\u5b50\u4f9b\u306b\u306a\u308a\u307e\u3059\u3002\u96cc\u96c4\u540c\u4f53\u306e\u5375\u3068\u96c4\u306e\u7cbe\u5b50\u304c\u53d7\u7cbe\u3059\u308b\u5834\u5408\u3082\u3042\u308a\u307e\u3059\u3002<br>\u3000\u5375\u3084\u7cbe\u5b50\u306f\u3001\u304b\u3089\u3060\u306e\u4e2d\u306b\u3042\u308b\u751f\u6b96\u817a\u3068\u3088\u3070\u308c\u308b\u7d30\u9577\u3044\u30c1\u30e5\u30fc\u30d6\u306e\u3088\u3046\u306a\u5834\u6240\u3067\u4f5c\u3089\u308c\u307e\u3059\uff08\u56f31\uff09\u3002\u96cc\u96c4\u540c\u4f53\u306e\u4f53\u5185\u3067\u306f\u3001\u7cbe\u5b50\u306f\u300c\u8caf\u7cbe\u56a2\u300d\u3068\u3044\u3046\u5834\u6240\u306b\u4fdd\u7ba1\u3055\u308c\u3066\u3044\u307e\u3059\u3002\u751f\u6b96\u817a\u3067\u4f5c\u3089\u308c\u305f\u5375\u306f\u3001\u305f\u304f\u3055\u3093\u306e\u7cbe\u5b50\u304c\u5165\u3063\u305f\u8caf\u7cbe\u56a2\u306b\u5411\u3051\u3066\u62bc\u3057\u51fa\u3055\u308c\u3001\u305d\u308c\u3068\u540c\u6642\u306b\u305f\u3060\u3072\u3068\u3064\u306e\u7cbe\u5b50\u3068\u53d7\u7cbe\u3057\u307e\u3059\u3002\u53d7\u7cbe\u5375\u306f\u305d\u306e\u5f8c\u3001\u8caf\u7cbe\u56a2\u304b\u3089\u96a3\u306e\u5b50\u5bae\u3078\u62bc\u3057\u51fa\u3055\u308c\u3001\u3057\u3070\u3089\u304f\u3059\u308b\u3068\u81ea\u8eab\u306e\u5468\u56f2\u306b\u786c\u3044\u6bbb\uff08\u5375\u6bbb\uff09\u3092\u4f5c\u308a\u307e\u3059\u3002\u53d7\u7cbe\u3057\u3066\u7d041\u6642\u9593\u5f8c\u306b\u306f\u5375\u6bbb\u306e\u4e2d\u3067\u6700\u521d\u306e\u7d30\u80de\u5206\u88c2\u304c\u59cb\u307e\u308a\u3001\u3055\u3089\u306b\u5206\u88c2\u3092\u7e70\u308a\u8fd4\u3057\u306a\u304c\u3089\u3060\u3093\u3060\u3093\u3068\u7dda\u866b\u306e\u304b\u305f\u3061\u304c\u3067\u304d\u3066\u304d\u307e\u3059\u3002\u3053\u306e\u9593\u306b\u53d7\u7cbe\u5375\u306f\u4f53\u5916\u306b\u7523\u5375\u3055\u308c\u3001\u53d7\u7cbe\u3057\u3066\u304b\u3089\u7d0414\u6642\u9593\u5f8c\u306b\u306f\u5c0f\u3055\u306a\u5e7c\u866b\u304c\u5375\u306e\u6bbb\u304b\u3089\u51fa\u3066\u304d\u307e\u3059\u3002<\/p>\n\n\n<div class=\"wp-block-image\">\n<figure class=\"aligncenter size-full is-resized\"><img decoding=\"async\" width=\"1140\" height=\"454\" src=\"https:\/\/plaza.umin.ac.jp\/wormjp\/wordpress\/wp-content\/uploads\/2025\/01\/2-2_01.png\" alt=\"\" class=\"wp-image-386\" style=\"width:800px\" srcset=\"https:\/\/plaza.umin.ac.jp\/wormjp\/wordpress\/wp-content\/uploads\/2025\/01\/2-2_01.png 1140w, https:\/\/plaza.umin.ac.jp\/wormjp\/wordpress\/wp-content\/uploads\/2025\/01\/2-2_01-300x119.png 300w, https:\/\/plaza.umin.ac.jp\/wormjp\/wordpress\/wp-content\/uploads\/2025\/01\/2-2_01-1024x408.png 1024w, https:\/\/plaza.umin.ac.jp\/wormjp\/wordpress\/wp-content\/uploads\/2025\/01\/2-2_01-768x306.png 768w, https:\/\/plaza.umin.ac.jp\/wormjp\/wordpress\/wp-content\/uploads\/2025\/01\/2-2_01-670x267.png 670w\" sizes=\"(max-width: 1140px) 100vw, 1140px\" \/><\/figure>\n<\/div>\n\n\n<h4 class=\"wp-block-heading\">\u7dda\u866b\u3092\u4f7f\u3063\u3066\u751f\u547d\u8a95\u751f\u306e\u8b0e\u306b\u8feb\u308b<\/h4>\n\n\n\n<p>\u3000\u5375\u3068\u7cbe\u5b50\u306f\u907a\u4f1d\u5b50\uff08DNA\uff09\u3092\u5b50\u5b6b\u306b\u904b\u3076\u305f\u3081\u306e\u7279\u5225\u306a\u7d30\u80de\u3067\u3059\u3002\u305d\u308c\u3089\u304c\u53d7\u7cbe\u3059\u308b\u3053\u3068\u306b\u3088\u3063\u3066\u3001\u3042\u3089\u3086\u308b\u7a2e\u985e\u306e\u7d30\u80de\u306b\u306a\u308b\u3053\u3068\u304c\u3067\u304d\u308b\u80fd\u529b\uff08\u5168\u80fd\u6027\uff09\u3092\u6301\u3063\u305f\u7d30\u80de\u3078\u3068\u5909\u5316\u3057\u307e\u3059\u3002\u7dda\u866b\u306f\u4f53\u304c\u900f\u660e\u306a\u306e\u3067\u3001\u5375\u3084\u7cbe\u5b50\u304c\u4f5c\u3089\u308c\u308b\u6642\u671f\u304b\u3089\u53d7\u7cbe\u306e\u77ac\u9593\u3001\u3055\u3089\u306b\u53d7\u7cbe\u5375\u306e\u4e2d\u3067\u4f55\u304c\u8d77\u3053\u3063\u3066\u3044\u308b\u306e\u304b\u3092\u3001\u751f\u304d\u305f\u307e\u307e\u9855\u5fae\u93e1\u3067\u89b3\u5bdf\u3059\u308b\u3053\u3068\u304c\u3067\u304d\u307e\u3059\u3002\u3053\u306e\u7279\u5fb4\u3092\u6d3b\u304b\u3059\u3053\u3068\u306b\u3088\u3063\u3066\u3001\u53d7\u7cbe\u5375\u306e\u4e2d\u3067\u7e70\u308a\u5e83\u3052\u3089\u308c\u308b\u751f\u547d\u8a95\u751f\u306e\u79d8\u5bc6\u304c\u6b21\u3005\u3068\u89e3\u304d\u660e\u304b\u3055\u308c\u3066\u3044\u307e\u3059\u3002<br>\u3000\u305f\u3068\u3048\u3070\u3001\u53d7\u7cbe\u5375\u306e\u4e2d\u3067\u306f\u3001\u5375\u3084\u7cbe\u5b50\u306b\u7531\u6765\u3059\u308b\u4e0d\u8981\u3068\u306a\u3063\u305f\u6210\u5206\u3092\u5206\u89e3\u3057\u3064\u3064\u3082\u3001\u305d\u306e\u7d20\u6750\u3092\u30ea\u30b5\u30a4\u30af\u30eb\u3059\u308b\u3053\u3068\u306b\u3088\u3063\u3066\u3001\u305d\u306e\u5f8c\u306e\u767a\u751f\u306b\u5fc5\u8981\u306a\u6210\u5206\u3078\u3068\u7f6e\u304d\u63db\u3048\u308b\u3001\u3044\u308f\u3086\u308b\u30b9\u30af\u30e9\u30c3\u30d7\u30fb\u30a2\u30f3\u30c9\u30fb\u30d3\u30eb\u30c9\u304c\u8d77\u304d\u3066\u3044\u308b\u3053\u3068\u304c\u308f\u304b\u3063\u3066\u304d\u307e\u3057\u305f\u3002\u3053\u306e\u3088\u3046\u306a\u73fe\u8c61\u306f\u591a\u304f\u306e\u52d5\u7269\u306e\u53d7\u7cbe\u5375\u306b\u5171\u901a\u3059\u308b\u3053\u3068\u3082\u308f\u304b\u3063\u3066\u304d\u3066\u3044\u307e\u3059\u3002<br>\u3000\u4e0d\u601d\u8b70\u306a\u3053\u3068\u306b\u3001\u7dda\u866b\u3084\u30d2\u30c8\u306e\u5375\u306f\u305f\u304f\u3055\u3093\u306e\u7cbe\u5b50\u306b\u56f2\u307e\u308c\u3066\u3082\u5fc5\u305a\u3072\u3068\u3064\u306e\u7cbe\u5b50\u3068\u306e\u307f\u53d7\u7cbe\u3057\u307e\u3059\u30022\u3064\u4ee5\u4e0a\u306e\u7cbe\u5b50\u3068\u53d7\u7cbe\uff08\u591a\u7cbe\uff09\u3059\u308b\u3068\u96c4\u7531\u6765\u306e\u907a\u4f1d\u5b50\u304c\u591a\u304f\u306a\u3063\u3066\u3057\u307e\u3046\u306e\u3067\u3001\u3053\u308c\u3092\u9632\u3050\u3057\u304f\u307f\uff08\u591a\u7cbe\u62d2\u5426\uff09\u304c\u5099\u308f\u3063\u3066\u3044\u308b\u306e\u3067\u3059\u3002\u7dda\u866b\u3067\u306f\u53d7\u7cbe\u5f8c5\u5206\u3050\u3089\u3044\u3067\u3067\u304d\u308b\u5375\u306e\u6bbb\u304c\u30012\u3064\u76ee\u306e\u7cbe\u5b50\u306e\u53d7\u7cbe\u3092\u9632\u3050\u3053\u3068\u304c\u77e5\u3089\u308c\u3066\u3044\u307e\u3059\u3002\u307e\u305f\u6700\u8fd1\u306e\u7814\u7a76\u304b\u3089\u3001\u3072\u3068\u3064\u76ee\u306e\u7cbe\u5b50\u304c\u53d7\u7cbe\u3057\u3066\u304b\u3089\u6570\u79d2\u4ee5\u5185\u306b\u50cd\u304f\u3059\u3070\u3084\u3044\u591a\u7cbe\u62d2\u5426\u306e\u3057\u304f\u307f\u3082\u3042\u308b\u3053\u3068\u304c\u308f\u304b\u3063\u3066\u304d\u307e\u3057\u305f\u3002\u3053\u306e\u3088\u3046\u306b\u7dda\u866b\u306e\u5375\u306f\u53d7\u7cbe\u76f4\u5f8c\u3068\u5375\u6bbb\u5f62\u6210\u6642\u306e2\u6bb5\u968e\u306e\u591a\u7cbe\u62d2\u5426\u306e\u3057\u304f\u307f\u306b\u3088\u308a\u3001\u305f\u3060\u3072\u3068\u3064\u306e\u7cbe\u5b50\u3068\u306e\u307f\u53d7\u7cbe\u3059\u308b\u3088\u3046\u306b\u306a\u3063\u3066\u3044\u307e\u3059\uff08\u56f3\uff12\uff09\u3002<\/p>\n\n\n<div class=\"wp-block-image\">\n<figure class=\"aligncenter size-full is-resized\"><img decoding=\"async\" width=\"1280\" height=\"427\" src=\"https:\/\/plaza.umin.ac.jp\/wormjp\/wordpress\/wp-content\/uploads\/2025\/01\/2-2_02-e1736477920530.png\" alt=\"\" class=\"wp-image-396\" style=\"width:800px\" srcset=\"https:\/\/plaza.umin.ac.jp\/wormjp\/wordpress\/wp-content\/uploads\/2025\/01\/2-2_02-e1736477920530.png 1280w, https:\/\/plaza.umin.ac.jp\/wormjp\/wordpress\/wp-content\/uploads\/2025\/01\/2-2_02-e1736477920530-300x100.png 300w, https:\/\/plaza.umin.ac.jp\/wormjp\/wordpress\/wp-content\/uploads\/2025\/01\/2-2_02-e1736477920530-1024x342.png 1024w, https:\/\/plaza.umin.ac.jp\/wormjp\/wordpress\/wp-content\/uploads\/2025\/01\/2-2_02-e1736477920530-768x256.png 768w, https:\/\/plaza.umin.ac.jp\/wormjp\/wordpress\/wp-content\/uploads\/2025\/01\/2-2_02-e1736477920530-670x224.png 670w\" sizes=\"(max-width: 1280px) 100vw, 1280px\" \/><\/figure>\n<\/div>\n\n\n<h4 class=\"wp-block-heading\">\u30df\u30c8\u30b3\u30f3\u30c9\u30ea\u30a2\u907a\u4f1d\u5b50\u306f\u6bcd\u6027\u907a\u4f1d\u3059\u308b<\/h4>\n\n\n\n<p>\u3000\u907a\u4f1d\u5b50\u306f\u7d30\u80de\u306e\u4e2d\u306e\u300c\u6838\u300d\u306b\u4fdd\u7ba1\u3055\u308c\u3066\u3044\u3066\u3044\u307e\u3059\u304c\u3001\u6838\u4ee5\u5916\u306b\u3082\u907a\u4f1d\u5b50\u304c\u5b58\u5728\u3059\u308b\u5834\u6240\u304c\u3042\u308a\u307e\u3059\u3002\u305d\u308c\u304c\u30df\u30c8\u30b3\u30f3\u30c9\u30ea\u30a2\u306e\u4e2d\u3067\u3059\u3002\u30df\u30c8\u30b3\u30f3\u30c9\u30ea\u30a2\u306f\u7d30\u80de\u306e\u4e2d\u306b\u3042\u308b\u7d30\u80de\u5c0f\u5668\u5b98\u306e1\u7a2e\u3067\u3001\u30a8\u30cd\u30eb\u30ae\u30fc\u3092\u4f5c\u308b\u767a\u96fb\u6240\u306e\u3088\u3046\u306a\u5f79\u5272\u3092\u3057\u3066\u3044\u307e\u3059\u3002\u30df\u30c8\u30b3\u30f3\u30c9\u30ea\u30a2\u306f\u9032\u5316\u306e\u904e\u7a0b\u3067\u7d30\u83cc\u304c\u7d30\u80de\u306e\u4e2d\u306b\u4f4f\u307f\u7740\u3044\u305f\uff08\u5171\u751f\u3059\u308b\uff09\u3053\u3068\u3067\u751f\u307e\u308c\u305f\u3068\u8003\u3048\u3089\u308c\u3066\u304a\u308a\u3001\u305d\u306e\u305f\u3081\u7d30\u83cc\u306b\u7531\u6765\u3059\u308b\u72ec\u81ea\u306e\u907a\u4f1d\u5b50\uff08DNA\uff09\u3092\u6301\u3064\u306e\u3067\u3059\u3002<br>\u3000\u6838\u306e\u907a\u4f1d\u5b50\u306f\u6bcd\u89aa\uff08\u5375\uff09\u3068\u7236\u89aa\uff08\u7cbe\u5b50\uff09\u304b\u3089\u534a\u5206\u305a\u3064\u5b50\u5b6b\u3078\u4f1d\u308f\u308a\u307e\u3059\u3002\u4e0d\u601d\u8b70\u306a\u3053\u3068\u306b\u30df\u30c8\u30b3\u30f3\u30c9\u30ea\u30a2\u907a\u4f1d\u5b50\u306f\u591a\u304f\u306e\u751f\u7269\u3067\u6bcd\u89aa\u304b\u3089\u306e\u307f\u5b50\u5b6b\u306b\u4f1d\u308f\u308b\u306e\u3067\u3001\u3053\u306e\u3088\u3046\u306a\u907a\u4f1d\u306e\u3057\u304b\u305f\u306f\u300c\u6bcd\u6027\u907a\u4f1d\u300d\u3068\u547c\u3070\u308c\u3066\u3044\u307e\u3059\uff08\u56f3\uff13\uff09\u3002\u7dda\u866b\u3067\u3082\u96cc\u96c4\u540c\u4f53\u306e\u5375\u3068\u96c4\u306e\u7cbe\u5b50\u304c\u53d7\u7cbe\u3057\u305f\u5834\u5408\u306f\u30df\u30c8\u30b3\u30f3\u30c9\u30ea\u30a2\u907a\u4f1d\u5b50\u304c\u6bcd\u6027\u907a\u4f1d\u3057\u307e\u3059\u3002\u305d\u306e\u3057\u304f\u307f\u3084\u7406\u7531\u306f\u8b0e\u306b\u3064\u3064\u307e\u308c\u3066\u3044\u307e\u3057\u305f\u304c\u3001\u7dda\u866b\u306e\u7814\u7a76\u304b\u3089\u300c\u30aa\u30fc\u30c8\u30d5\u30a1\u30b8\u30fc\u300d\u3068\u3044\u3046\u3057\u304f\u307f\u304c\u50cd\u3044\u3066\u3044\u308b\u3053\u3068\u304c\u308f\u304b\u3063\u3066\u304d\u307e\u3057\u305f\u3002<br>\u3000\u53d7\u7cbe\u3059\u308b\u3068\u7cbe\u5b50\u306e\u30df\u30c8\u30b3\u30f3\u30c9\u30ea\u30a2\u306f\u5375\u306e\u4e2d\u306b\u5165\u3063\u3066\u304d\u307e\u3059\u304c\u3001\u3057\u3070\u3089\u304f\u3059\u308b\u3068\u7cbe\u5b50\u306e\u30df\u30c8\u30b3\u30f3\u30c9\u30ea\u30a2\u306e\u5468\u56f2\u306b\u30aa\u30fc\u30c8\u30d5\u30a1\u30b4\u30bd\u30fc\u30e0\u3068\u3044\u3046\u888b\u306e\u3088\u3046\u306a\u69cb\u9020\u304c\u3067\u304d\u3066\u304d\u3066\u3001\u4e2d\u8eab\u3092\u4e38\u3054\u3068\u5206\u89e3\u3057\u3066\u3057\u307e\u3046\u306e\u3067\u3059\uff08\u56f3\uff13\uff09\u3002\u3067\u306f\u3001\u3069\u3046\u3057\u3066\u5375\u306e\u30df\u30c8\u30b3\u30f3\u30c9\u30ea\u30a2\u306f\u5206\u89e3\u3055\u308c\u305a\u3001\u7cbe\u5b50\u306e\u30df\u30c8\u30b3\u30f3\u30c9\u30ea\u30a2\u3060\u3051\u5206\u89e3\u3055\u308c\u308b\u306e\u3067\u3057\u3087\u3046\u304b\uff1f\u305d\u308c\u306b\u3064\u3044\u3066\u306f\u73fe\u5728\u3082\u5f15\u304d\u7d9a\u304d\u7814\u7a76\u304c\u9032\u3081\u3089\u308c\u3066\u3044\u307e\u3059\u3002\u307e\u305f\u3001\u9762\u767d\u3044\u3053\u3068\u306b\u30d2\u30c8\u306e\u7d30\u80de\u306b\u611f\u67d3\u3057\u305f\u7d30\u83cc\u3082\u7cbe\u5b50\u306e\u30df\u30c8\u30b3\u30f3\u30c9\u30ea\u30a2\u3068\u540c\u3058\u3088\u3046\u306b\u30aa\u30fc\u30c8\u30d5\u30a1\u30b8\u30fc\u3067\u5206\u89e3\u3055\u308c\u308b\u3053\u3068\u3082\u308f\u304b\u3063\u3066\u304d\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n<div class=\"wp-block-image\">\n<figure class=\"aligncenter size-full is-resized\"><img decoding=\"async\" width=\"1280\" height=\"427\" src=\"https:\/\/plaza.umin.ac.jp\/wormjp\/wordpress\/wp-content\/uploads\/2025\/01\/2-2_03-e1736478031639.png\" alt=\"\" class=\"wp-image-397\" style=\"width:800px\" srcset=\"https:\/\/plaza.umin.ac.jp\/wormjp\/wordpress\/wp-content\/uploads\/2025\/01\/2-2_03-e1736478031639.png 1280w, https:\/\/plaza.umin.ac.jp\/wormjp\/wordpress\/wp-content\/uploads\/2025\/01\/2-2_03-e1736478031639-300x100.png 300w, https:\/\/plaza.umin.ac.jp\/wormjp\/wordpress\/wp-content\/uploads\/2025\/01\/2-2_03-e1736478031639-1024x342.png 1024w, https:\/\/plaza.umin.ac.jp\/wormjp\/wordpress\/wp-content\/uploads\/2025\/01\/2-2_03-e1736478031639-768x256.png 768w, https:\/\/plaza.umin.ac.jp\/wormjp\/wordpress\/wp-content\/uploads\/2025\/01\/2-2_03-e1736478031639-670x224.png 670w\" sizes=\"(max-width: 1280px) 100vw, 1280px\" \/><\/figure>\n<\/div>\n\n\n<p><strong>\u53c2\u8003\u8cc7\u6599<\/strong><br>1) Hall, D.H., Herndon, L.A. and Altun, Z.\u8457 \u300cIntroduction to <em>C. elegans<\/em> Embryo Anatomy\u300d2017\u5e74 In WormAtlas. doi:10.3908\/wormatlas.4.1<br>2) \u5927\u5cf6\u9756\u7f8e \u8457\uff0e\u300c\u7dda\u866b\u306e\u7814\u7a76\u3068\u30ce\u30fc\u30d9\u30eb\u8cde\u3078\u306e\u9053\uff0d1\u30df\u30ea\u306e\u866b\u306e\u7814\u7a76\u304c\u306a\u305c3\u5ea6\u30ce\u30fc\u30d9\u30eb\u8cde\u3092\u53d7\u8cde\u3057\u305f\u304b\uff0d\u300d2015\u5e74\u3000\u88f3\u83ef\u623f\u3000ISBN 978-4-7853-5863-1\uff0e<br>3) \u300c\u591a\u7cbe\u5b50\u53d7\u7cbe\u62d2\u5426\u306e\u4ed5\u7d44\u307f\u306e\u4e00\u7aef\u3092\u89e3\u660e \uff5e\u306a\u305c\u5375\u6bcd\u7d30\u80de\uff08\u5375\u5b50\uff09\u306f\u305f\u3060\uff11\u3064\u306e\u7cbe\u5b50\u3068\u306e\u307f\u53d7\u7cbe\u3059\u308b\u306e\u304b\uff5e\u300d2024\u5e74\u3000\u7fa4\u99ac\u5927\u5b66\u751f\u4f53\u8abf\u7bc0\u7814\u7a76\u6240HP \u30d7\u30ec\u30b9\u30ea\u30ea\u30fc\u30b9\u8a18\u4e8b <a href=\"https:\/\/www.imcr.gunma-u.ac.jp\/cms_imcr\/wp-content\/uploads\/2024\/01\/dcb83577e9795fdcc9bc08cd5c98b4f1.pdf\">https:\/\/www.imcr.gunma-u.ac.jp\/cms_imcr\/wp-content\/uploads\/2024\/01\/dcb83577e9795fdcc9bc08cd5c98b4f1.pdf<\/a><br>4) \u4f50\u85e4\u7f8e\u7531\u7d00\uff0c\u4f50\u85e4\u88d5\u516c\uff0c\u4f50\u85e4\u5065\u3000\u8457\uff0e\u300c\u521d\u671f\u767a\u751f\u306b\u304a\u3051\u308b\u30ea\u30bd\u30bd\u30fc\u30e0\u5206\u89e3\u306e\u751f\u7406\u6a5f\u80fd\u3068\u5206\u5b50\u30e1\u30ab\u30cb\u30ba\u30e0\u300d2019\u5e74\u3000\u751f\u5316\u5b66\u300091(5):643-651. <a href=\"https:\/\/seikagaku.jbsoc.or.jp\/10.14952\/SEIKAGAKU.2019.910643\/data\/index.html\">https:\/\/seikagaku.jbsoc.or.jp\/10.14952\/SEIKAGAKU.2019.910643\/data\/index.html<\/a><br>5) \u4f50\u85e4\u7f8e\u7531\u7d00 \u8457\u3000\u300c\u7236\u7531\u6765\u306e\u30df\u30c8\u30b3\u30f3\u30c9\u30ea\u30a2\u30b2\u30ce\u30e0\u304c\u6d88\u3055\u308c\u308b\u3057\u304f\u307f\u300d2015\u5e74\u3000JT\u751f\u547d\u8a8c\u7814\u7a76\u9928\u3000\u5b63\u520a\u300c\u751f\u547d\u8a8c\u300d85\u53f7\uff0e <a href=\"https:\/\/www.brh.co.jp\/publication\/journal\/085\/research\/2\">https:\/\/www.brh.co.jp\/publication\/journal\/085\/research\/2<\/a><\/p>\n\n\n\n<p><strong>\u76e3\u4fee\u8005<\/strong><br>\u4f50\u85e4\u7f8e\u7531\u7d00\u3000\u3000<br>\u5c90\u961c\u770c\u751f\u307e\u308c\u3002\u6771\u4eac\u5927\u5b66\u5927\u5b66\u9662\u535a\u58eb\u8ab2\u7a0b\u4fee\u4e86\u3002\u73fe\u5728\u306f\u7fa4\u99ac\u5927\u5b66\u30fb\u751f\u4f53\u8abf\u7bc0\u7814\u7a76\u6240\u6559\u6388\u3068\u3057\u3066\u3001\u30df\u30c8\u30b3\u30f3\u30c9\u30ea\u30a2\u907a\u4f1d\u5b50\u306e\u6bcd\u6027\u907a\u4f1d\u3084\u751f\u6b96\u7d30\u80de\u3067\u306e\u30aa\u30fc\u30c8\u30d5\u30a1\u30b8\u30fc\u306e\u5f79\u5272\u306b\u3064\u3044\u3066\u7814\u7a76\u3002<br><br> \u4f50\u85e4\u5065\u3000\u3000<br>\u5927\u5206\u770c\u751f\u307e\u308c\u3002\u6771\u4eac\u5927\u5b66\u5927\u5b66\u9662\u535a\u58eb\u8ab2\u7a0b\u4fee\u4e86\u3002\u73fe\u5728\u3001\u7fa4\u99ac\u5927\u5b66\u30fb\u751f\u4f53\u8abf\u7bc0\u7814\u7a76\u6240\u30fb\u7d30\u80de\u69cb\u9020\u5206\u91ce\u6559\u6388\u3068\u3057\u3066\u3001\u7dda\u866b\u3084\u30de\u30a6\u30b9\u3092\u7528\u3044\u3066\u52d5\u7269\u304c\u53d7\u7cbe\u3057\u3066\u767a\u751f\u3059\u308b\u969b\u306b\u7e70\u308a\u5e83\u3052\u3089\u308c\u308b\u7d30\u80de\u5185\u30ea\u30e2\u30c7\u30ea\u30f3\u30b0\u306e\u73fe\u8c61\u306b\u3064\u3044\u3066\u7814\u7a76\u3057\u3066\u3044\u308b\u3002\u65e5\u672c\u751f\u5316\u5b66\u4f1a\u7406\u4e8b\u306a\u3069\u3082\u52d9\u3081\u308b\u3002<\/p>\n\n\n\n<p><strong>\u7814\u7a76\u5ba4HP<\/strong><br><a href=\"http:\/\/makukinou.showa.gunma-u.ac.jp\/index.html\">http:\/\/makukinou.showa.gunma-u.ac.jp\/index.html<\/a><br><a href=\"http:\/\/traffic.dept.med.gunma-u.ac.jp\/\">http:\/\/traffic.dept.med.gunma-u.ac.jp\/<\/a><\/p>\n\n\n\n<p class=\"has-text-align-right has-small-font-size\">\u00a92026 \u4f50\u85e4\u7f8e\u7531\u7d00\u30fb\u4f50\u85e4\u5065\u300c2.\u3000\u53d7\u7cbe\u3000\uff5e\u751f\u547d\u8a95\u751f\u306e\u77ac\u9593\uff5e\u300d<a href=\"https:\/\/creativecommons.org\/licenses\/by-sa\/4.0\/\">CC BY SA<\/a><\/p>\n\n\n\n<p class=\"has-text-align-right\"><a href=\"#toc_container\" data-type=\"internal\" data-id=\"#toc_container\">\u76ee\u6b21\u30da\u30fc\u30b8\u3078\u2191<\/a><\/p>\n\n\n\n<div style=\"height:20px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n<\/div><\/section>\n\n\n\n<section id=\"section-3\" class=\"wp-block-group\"><div class=\"wp-block-group__inner-container is-layout-constrained wp-block-group-is-layout-constrained\">\n<h3 class=\"wp-block-heading\">3.\u3000\u7dda\u866b\u304c\u5375\u304b\u3089\u4f53\u306e\u5f62\u3092\u4f5c\u308b\u521d\u671f\u306e\u904e\u7a0b\u2015\u6d41\u308c\u3001\u56de\u8ee2\u3001\u3081\u308a\u8fbc\u307f\u304c\u9375\u3068\u306a\u308b\u30e1\u30ab\u30cb\u30ba\u30e0<\/h3>\n\n\n\n<h4 class=\"wp-block-heading\">\u521d\u671f\u767a\u751f\u3068\u306f\uff1f\u7dda\u866b\u3092\u4f7f\u3063\u305f\u521d\u671f\u767a\u751f\u7814\u7a76\u304c\u306a\u305c\u91cd\u8981\uff1f<\/h4>\n\n\n\n<p>\u3000\u500b\u4f53\u767a\u751f\u3068\u306f\u3001\u751f\u7269\u306e\u500b\u4f53\u304c\u53d7\u7cbe\u5375\u306e\u3088\u3046\u306a\u672a\u719f\u306a\u72b6\u614b\u304b\u3089\u6210\u4f53\u306b\u306a\u308b\u307e\u3067\u306e\u904e\u7a0b\u306e\u3053\u3068\u3067\u3059\u3002\u305d\u306e\u4e2d\u3067\u3082\u521d\u671f\u306b\u8d77\u3053\u308b\u4e00\u9023\u306e\u30a4\u30d9\u30f3\u30c8\u304c\u521d\u671f\u767a\u751f\u3067\u3059\u3002\u3053\u306e\u904e\u7a0b\u3067\u306f\uff11\uff09\u4f53\u306e\u524d\u5f8c\u3001\u80cc\u8179\u3001\u5de6\u53f3\u306e\u65b9\u5411\u3092\u6c7a\u5b9a\u3057\u305f\u308a\u3001\uff12\uff09\u69d8\u3005\u306a\u7a2e\u985e\u306e\u7d30\u80de\u30bf\u30a4\u30d7\u3092\u4f5c\u3063\u305f\u308a\u3001\uff13\uff09\u305d\u306e\u7d30\u80de\u305f\u3061\u3092\u6b63\u3057\u304f\u914d\u7f6e\u3057\u305f\u308a\u3001\u3059\u308b\u5fc5\u8981\u304c\u3042\u308a\u307e\u3059\u3002<br>\u3000\u7dda\u866b\u306e\u521d\u671f\u80da\u306f\u89b3\u5bdf\u3084\u64cd\u4f5c\u304c\u3057\u3084\u3059\u304f\u3001\u307e\u305f\u3001\u521d\u671f\u767a\u751f\u306e\u30a4\u30d9\u30f3\u30c8\u306b\u7570\u5e38\u304c\u3042\u308b\u5909\u7570\u4f53\u3092\u5f97\u3084\u3059\u3044\u3068\u3044\u3046\u91cd\u8981\u306a\u5229\u70b9\u304c\u3042\u308a\u307e\u3059\u3002\u3053\u306e\u5909\u7570\u4f53\u306eDNA\u306e\u4e2d\u3067\u3069\u306e\u907a\u4f1d\u5b50\u304c\u5909\u7570\u3057\u3066\u3044\u308b\u304b\u3092\u8abf\u3079\u308b\u3053\u3068\u306b\u3088\u3063\u3066\u3001\u521d\u671f\u767a\u751f\u3092\u652f\u914d\u3059\u308b\u907a\u4f1d\u5b50\u7fa4\uff08\u5f8c\u8ff0\u3059\u308ba-PAR, p-PAR\uff09\u306a\u3069\u304c\u521d\u3081\u3066\u540c\u5b9a\u3055\u308c\u307e\u3057\u305f\u3002\u3053\u306e\u3088\u3046\u306a\u907a\u4f1d\u5b50\u306f\u30d2\u30c8\u3067\u3082\u4fdd\u5b58\u3055\u308c\u3066\u3044\u307e\u3059\u3002<br>\u3000\u6700\u8fd1\u3067\u3082\u3001\u5f8c\u8ff0\u3059\u308b\u904b\u547d\u6c7a\u5b9a\u56e0\u5b50\u306e\u4e00\u3064\u3067\u3042\u308b\u751f\u6b96\u9846\u7c92\u304c\u3001\u6c34\u306e\u4e2d\u306b\u3042\u308b\u6cb9\u6ef4\u306e\u3088\u3046\u306b\u201c\u5206\u96e2\u201d\u3059\u308b\u3053\u3068\u3067\u5f62\u6210\u3055\u308c\u308b\u3053\u3068\u304c\u3001\u521d\u3081\u3066\u7dda\u866b\u3067\u767a\u898b\u3055\u308c\u307e\u3057\u305f\u3002\u3053\u306e\u76f8\u5206\u96e2\u73fe\u8c61\u306f\u306e\u3061\u306b\u3055\u307e\u3056\u307e\u306a\u751f\u547d\u73fe\u8c61\u3067\u78ba\u8a8d\u3055\u308c\u3001\u8fd1\u5e74\u306e\u7d30\u80de\u751f\u7269\u5b66\u306e\u4e2d\u3067\u4e00\u5927\u6f6e\u6d41\uff08\u3044\u308f\u3086\u308b\u30d0\u30ba\u308a\u3067\u3059\uff09\u3092\u8d77\u3053\u3057\u3066\u3044\u307e\u3059\u3002<br>\u3000\u3053\u306e\u3088\u3046\u306b\u3001\u7dda\u866b\u306f\u4e00\u898b\u5358\u7d14\u306a\u69cb\u9020\u3092\u3057\u3066\u3044\u307e\u3059\u304c\u3001\u7814\u7a76\u8005\u305f\u3061\u304c\u65b0\u3057\u3044\u56e0\u5b50\u3092\u201c\u898b\u3064\u3051\u308b\u201d\u3053\u3068\u304c\u3067\u304d\u3001 \u201c\u6df1\u304f\u201d\u4ed5\u7d44\u307f\u3092\u7406\u89e3\u3057\u3001\u9769\u65b0\u7684\u306a\u30a2\u30a4\u30c7\u30a2\u3092\u201c\u8a66\u3059\u201d\u3053\u3068\u304c\u3057\u3084\u3059\u3044\u306e\u3067\u3001\u7814\u7a76\u754c\u306b\u304a\u3044\u3066\u3057\u3070\u3057\u3070\u30c8\u30ec\u30f3\u30c9\u30ea\u30fc\u30c0\u30fc\u306b\u306a\u308b\u3053\u3068\u304c\u3042\u308b\u306e\u3067\u3059\u3002\u305f\u307e\u306b\u9593\u9055\u3063\u305f\u4eee\u8aac\u304c\u6a2a\u884c\u3059\u308b\u3053\u3068\u3082\u3042\u308a\u307e\u3059\u304c\u3001\u5de8\u8996\u7684\u306b\u898b\u308b\u3068\u79d1\u5b66\u754c\u306f\u5efa\u8a2d\u7684\u306a\u6279\u5224\u306e\u5fdc\u916c\u306b\u3088\u308b\u81ea\u5df1\u4fee\u5fa9\u80fd\u529b\u3092\u6301\u3063\u3066\u3044\u308b\u306e\u3067\u3001\u9593\u9055\u3063\u305f\u4eee\u8aac\u306f\u5fd8\u308c\u3089\u308c\u3066\u3044\u304d\u307e\u3059\u3002<\/p>\n\n\n\n<div class=\"wp-block-columns is-layout-flex wp-container-core-columns-is-layout-9d6595d7 wp-block-columns-is-layout-flex\">\n<div class=\"wp-block-column is-layout-flow wp-block-column-is-layout-flow\" style=\"flex-basis:50%\">\n<h4 class=\"wp-block-heading\">\u4f53\u306e\u524d\u5f8c\u3001\u80cc\u8179\u3001\u5de6\u53f3\u8ef8\u304c\u3067\u304d\u308b\u304d\u3063\u304b\u3051<\/h4>\n\n\n\n<p>\u3000\u307b\u307c\u5168\u3066\u306e\u52d5\u7269\u306e\u521d\u671f\u767a\u751f\u3067\u306f\u3001\u307e\u305a\u304b\u3089\u3060\u306e\u524d\u5f8c\u3092\u6c7a\u3081\u308b\u5fc5\u8981\u304c\u3042\u308a\u307e\u3059\u3002\u524d\u5f8c\u8ef8\u306f\u9032\u5316\u7684\u306b\u6700\u3082\u53e4\u304f\u304b\u3089\u3042\u308b\u4f53\u8ef8\u3067\u3042\u308a\u3001\u52d5\u7269\u304c\u3048\u3055\u3092\u63a2\u3059\u3068\u304d\u306b\u52d5\u304d\u307e\u308f\u308b\u305f\u3081\u306b\u3082\u3001\u5c06\u6765\u304b\u3089\u3060\u306e\u3069\u3061\u3089\u5074\u304c\u53e3\u306b\u306a\u308b\u304b\u809b\u9580\u306b\u306a\u308b\u304b\u3092\u6c7a\u3081\u308b\u305f\u3081\u306b\u3082\u3001\u30af\u30e9\u30b2\u306e\u3088\u3046\u306a\u5358\u7d14\u306a\u69cb\u9020\u306e\u52d5\u7269\u304b\u3089\u30d2\u30c8\u306b\u81f3\u308b\u307e\u3067\u975e\u5e38\u306b\u91cd\u8981\u306a\u3082\u306e\u3067\u3059\u3002\u7dda\u866b\u3067\u306f\u3001\u7cbe\u5b50\u304c\u5375\u5b50\u306b\u5165\u308a\u3001\u7cbe\u5b50\u306b\u542b\u307e\u308c\u308b\u4e2d\u5fc3\u4f53\u3068\u3044\u3046\u30bf\u30f3\u30d1\u30af\u8cea\u3067\u3067\u304d\u305f\u7269\u4f53\u304c\u6d41\u308c\u3066\u6f02\u7740\u3059\u308b\u5834\u6240\u304c\u4f53\u306e\u5f8c\u308d\u5074\u3001\u3064\u307e\u308a\u5c06\u6765\u5c3b\u5c3e\u306b\u306a\u308b\u3088\u3046\u306b\u6c7a\u307e\u308a\u307e\u3059\uff08\u56f3\uff11\u4e0a\u6bb5\uff09\u3002\u3000\u3000\u3000<br>\u3000\u30af\u30e9\u30b2\u306b\u306f\u80cc\u8179\u306e\u9055\u3044\u306f\u3042\u308a\u307e\u305b\u3093\u304c\u3001\u7dda\u866b\u3092\u542b\u3080\u3001\u3088\u308a\u8907\u96d1\u306a\u52d5\u7269\u3067\u306f\u3001\u80cc\u5074\u3068\u8179\u5074\u3068\u3067\u304b\u3089\u3060\u306e\u6a5f\u80fd\u304c\u9055\u3063\u3066\u3044\u307e\u3059\u3002\u7dda\u866b\u3067\u306f\u30012\u7d30\u80de\u671f\u80da\u306e\u7d30\u80de\u304c\u5206\u88c2\u3059\u308b\u3068\u304d\u306b\u5375\u6bbb\u5185\u3067\u56de\u8ee2\u3059\u308b\u65b9\u5411\u306b\u3088\u3063\u3066\u80cc\u5074\u3068\u8179\u5074\u304c\u6c7a\u307e\u308a\u307e\u3059\uff08\u56f3\uff11\u4e2d\u6bb5\uff09\u3002\u524d\u5f8c\u3068\u80cc\u8179\u304c\u6c7a\u307e\u308b\u3068\u3001\u5e7e\u4f55\u7684\u306b\u81ea\u305a\u3068\u5de6\u53f3\u8ef8\u3082\u6c7a\u307e\u308a\u307e\u3059\u3002<br>\u3000\u5916\u5074\u304b\u3089\u898b\u308b\u3068\u3001\u30d2\u30c8\u3092\u542b\u3080\u591a\u304f\u306e\u52d5\u7269\u306e\u5de6\u53f3\u306f\u5bfe\u79f0\u306a\u69cb\u9020\u3067\u3059\u304c\u3001\u304b\u3089\u3060\u306e\u4e2d\u306e\u81d3\u5668\u306e\u914d\u7f6e\u3084\u5f62\u306f\u975e\u5bfe\u79f0\u306b\u306a\u3063\u3066\u3044\u307e\u3059\uff08\u5de6\u53f3\u5dee\u3068\u547c\u3073\u307e\u3059\uff09\u3002\u7dda\u866b\u306e\u5de6\u53f3\u5dee\u306f\u3001\uff14\u7d30\u80de\u671f\u80da\u306e\u7d30\u80de\u304c\u5206\u88c2\u3059\u308b\u3068\u304d\u306b\u56de\u8ee2\u3059\u308b\u3053\u3068\u3067\u751f\u307e\u308c\u307e\u3059\uff08\u56f3\uff11\u4e0b\u6bb5\uff09\u3002\u3053\u308c\u3089\u306e\u56de\u8ee2\u304c\u91cd\u8981\u3067\u3042\u308b\u3053\u3068\u306f\u3001\u305d\u306e\u5411\u304d\u3092\u5b9f\u9a13\u8005\u304c\u9006\u306b\u3059\u308b\u3053\u3068\u3067\u80cc\u8179\u3084\u5de6\u53f3\u306e\u81d3\u5668\u306e\u914d\u7f6e\u304c\u9006\u8ee2\u3057\u305f\u500b\u4f53\u304c\u751f\u307e\u308c\u308b\u3053\u3068\u306b\u3088\u308a\u793a\u3055\u308c\u307e\u3057\u305f\u3002<\/p>\n<\/div>\n\n\n\n<div class=\"wp-block-column is-layout-flow wp-block-column-is-layout-flow\" style=\"flex-basis:50%\"><div class=\"wp-block-image\">\n<figure class=\"aligncenter size-full\"><img decoding=\"async\" width=\"961\" height=\"1004\" src=\"https:\/\/plaza.umin.ac.jp\/wormjp\/wordpress\/wp-content\/uploads\/2025\/01\/2-3_01.jpg\" alt=\"\" class=\"wp-image-405\" srcset=\"https:\/\/plaza.umin.ac.jp\/wormjp\/wordpress\/wp-content\/uploads\/2025\/01\/2-3_01.jpg 961w, https:\/\/plaza.umin.ac.jp\/wormjp\/wordpress\/wp-content\/uploads\/2025\/01\/2-3_01-287x300.jpg 287w, https:\/\/plaza.umin.ac.jp\/wormjp\/wordpress\/wp-content\/uploads\/2025\/01\/2-3_01-768x802.jpg 768w, https:\/\/plaza.umin.ac.jp\/wormjp\/wordpress\/wp-content\/uploads\/2025\/01\/2-3_01-670x700.jpg 670w\" sizes=\"(max-width: 961px) 100vw, 961px\" \/><\/figure>\n<\/div><\/div>\n<\/div>\n\n\n\n<div class=\"wp-block-columns is-layout-flex wp-container-core-columns-is-layout-9d6595d7 wp-block-columns-is-layout-flex\">\n<div class=\"wp-block-column sp_box_ord_01 is-layout-flow wp-block-column-is-layout-flow\" style=\"flex-basis:50%\"><div class=\"wp-block-image\">\n<figure class=\"aligncenter size-full\"><img decoding=\"async\" width=\"827\" height=\"1280\" src=\"https:\/\/plaza.umin.ac.jp\/wormjp\/wordpress\/wp-content\/uploads\/2025\/01\/2-3_02.jpg\" alt=\"\" class=\"wp-image-406\" style=\"object-fit:cover\" srcset=\"https:\/\/plaza.umin.ac.jp\/wormjp\/wordpress\/wp-content\/uploads\/2025\/01\/2-3_02.jpg 827w, https:\/\/plaza.umin.ac.jp\/wormjp\/wordpress\/wp-content\/uploads\/2025\/01\/2-3_02-194x300.jpg 194w, https:\/\/plaza.umin.ac.jp\/wormjp\/wordpress\/wp-content\/uploads\/2025\/01\/2-3_02-662x1024.jpg 662w, https:\/\/plaza.umin.ac.jp\/wormjp\/wordpress\/wp-content\/uploads\/2025\/01\/2-3_02-768x1189.jpg 768w, https:\/\/plaza.umin.ac.jp\/wormjp\/wordpress\/wp-content\/uploads\/2025\/01\/2-3_02-670x1037.jpg 670w\" sizes=\"(max-width: 827px) 100vw, 827px\" \/><\/figure>\n<\/div><\/div>\n\n\n\n<div class=\"wp-block-column is-layout-flow wp-block-column-is-layout-flow\" style=\"flex-basis:50%\">\n<h4 class=\"wp-block-heading\">\u8272\u3005\u306a\u7d30\u80de\u304c\u3067\u304d\u308b\u4ed5\u7d44\u307f<\/h4>\n\n\n\n<p>\u3000\u3067\u306f\u306a\u305c\u3053\u306e\u3088\u3046\u306a\u6bd4\u8f03\u7684\u5358\u7d14\u306a\u3057\u304f\u307f\uff08\u6d41\u308c\u3001\u56de\u8ee2\uff09\u304c\u524d\u5f8c\u3001\u80cc\u8179\u3001\u5de6\u53f3\u306e\u5dee\u3092\u751f\u307f\u51fa\u3059\u304b\u3068\u3044\u3046\u3068\u3001\u4f53\u8ef8\u306b\u6cbf\u3063\u3066\u7d30\u80de\u306e\u7a2e\u985e\u306b\u9055\u3044\u304c\u751f\u307e\u308c\u308b\u304b\u3089\u3067\u3059\u3002<br>\u3000\u524d\u5f8c\u8ef8\u5f62\u6210\u6642\u306e\u4f8b\u3092\u7528\u3044\u3066\u8aac\u660e\u3057\u307e\u3059\u3002\u4e0a\u3067\u8ff0\u3079\u305f\u3088\u3046\u306b\u3001\u4f53\u306e\u524d\u5f8c\u8ef8\u306f\u7cbe\u5b50\u306b\u542b\u307e\u308c\u308b\u4e2d\u5fc3\u4f53\u304c\u6d41\u308c\u3066\u6f02\u7740\u3059\u308b\u5834\u6240\u3067\u6c7a\u307e\u308a\u307e\u3059\uff08\u56f31\u4e0a\u6bb5\uff09\u3002\u3053\u308c\u306f\u4e2d\u5fc3\u4f53\u3068\u3044\u3046\u7d30\u80de\u5c0f\u5668\u5b98\u306b\u542b\u307e\u308c\u308b\u30bf\u30f3\u30d1\u30af\u8cea\u304c\u53d7\u7cbe\u5375\u306e\u4e2d\u306b\u3042\u308b\u30bf\u30f3\u30d1\u30af\u8cea\u306b\u5f71\u97ff\u3092\u3082\u305f\u3089\u3059\u304b\u3089\u3067\u3059\uff08\u56f32\uff09\u3002<br>\u3000\u5177\u4f53\u7684\u306b\u3044\u3046\u3068\u3001a-PAR\u3068\u3044\u3046\u30bf\u30f3\u30d1\u30af\u8cea\u8907\u5408\u4f53\u3068p-PAR\u3068\u3044\u3046\u30bf\u30f3\u30d1\u30af\u8cea\u8907\u5408\u4f53\u304c\u3042\u308a\u3001\u53d7\u7cbe\u524d\u306f\u305d\u308c\u3089\u304c\u524d\u5f8c\u306e\u5dee\u306a\u304f\u4e00\u69d8\u306b\u5206\u5e03\u3057\u3066\u3044\u307e\u3059\u304c\uff08\u56f32\u4e0a2\u6bb5\uff09\u3001\u4e2d\u5fc3\u4f53\u7531\u6765\u306e\u523a\u6fc0\u306b\u3088\u308a\u7d30\u80de\u306e\u8868\u5c64\u306e\u6d41\u308c\u304c\u767a\u751f\u3057\u3066a-PAR\u304c\u524d\u5074\u306b\u904b\u3070\u308c\u3001\u3055\u3089\u306b\u5225\u306e\u3057\u304f\u307f\u306e\u52a9\u3051\u3082\u3042\u308ap-PAR\u304c\u5f8c\u308d\u5074\u306e\u8868\u5c64\u306b\u5c40\u5728\u3059\u308b\u3088\u3046\u306b\u306a\u308a\u307e\u3059\u3002\u3053\u306e\u975e\u5bfe\u79f0\u306a\u5c40\u5728\u304c\u3001\u3055\u3089\u306b\u4e0b\u6d41\u306e\u904b\u547d\u6c7a\u5b9a\u56e0\u5b50\u3068\u8a00\u308f\u308c\u308b\u30bf\u30f3\u30d1\u30af\u8cea\u306e\u5c40\u5728\u3092\u975e\u5bfe\u79f0\u306b\u5236\u5fa1\u3057\u307e\u3059\u3002\u3053\u308c\u306b\u3088\u308a\u3001\u53d7\u7cbe\u5375\u306e\u6700\u521d\u306e\u5375\u5272\u5f8c\u306b\u524d\u5074\u306e\u7d30\u80de\u306f\u4f53\u7d30\u80de\u306b\u3001\u5f8c\u308d\u5074\u306e\u7d30\u80de\u306f\u751f\u6b96\u7d30\u80de\u3092\u542b\u3080\u7d30\u80de\u306b\u306a\u308b\u201c\u904b\u547d\u201d\u304c\u6c7a\u5b9a\u3055\u308c\u307e\u3059\u3002<\/p>\n<\/div>\n<\/div>\n\n\n\n<div class=\"wp-block-columns is-layout-flex wp-container-core-columns-is-layout-9d6595d7 wp-block-columns-is-layout-flex\">\n<div class=\"wp-block-column is-layout-flow wp-block-column-is-layout-flow\" style=\"flex-basis:50%\">\n<h4 class=\"wp-block-heading\">\u4f53\u306e\u5f62\u3065\u304f\u308a\u306e\u4ed5\u7d44\u307f<\/h4>\n\n\n\n<p>\u3000\u3044\u308d\u3044\u308d\u306a\u7d30\u80de\u304c\u3067\u304d\u305f\u3060\u3051\u3067\u306f\u304b\u3089\u3060\u3092\u5f62\u4f5c\u308b\u306b\u306f\u4e0d\u5341\u5206\u3067\u3059\u3002\u305d\u308c\u3089\u304c\u5f62\u72b6\u3084\u914d\u7f6e\u3092\u5909\u3048\u3066\u3044\u304f\u5fc5\u8981\u304c\u3042\u308a\u307e\u3059\u3002\u305d\u306e\u4ee3\u8868\u7684\u306a\u4f8b\u304c\u539f\u8178\u9665\u5165\u3067\u3059\u300220\u4e16\u7d00\u3092\u4ee3\u8868\u3059\u308b\u8457\u540d\u306a\u767a\u751f\u751f\u7269\u5b66\u8005\u3067\u3042\u308b\u30a6\u30a9\u30eb\u30d1\u30fc\u30c8\u306f\u3001\u300c\u4eba\u751f\u306e\u4e2d\u3067\u6700\u3082\u91cd\u8981\u306a\u77ac\u9593\u306f\u51a0\u5a5a\u846c\u796d\u3067\u306f\u306a\u304f\u539f\u8178\u9665\u5165\u3067\u3042\u308b\u300d\u3068\u304b\u3064\u3066\u8a00\u3044\u307e\u3057\u305f\u3002<br>\u3000\u7dda\u866b\u306e\u539f\u8178\u9665\u5165\u306f\u6bd4\u8f03\u7684\u5358\u7d14\u3067\u3059\u304c\u3001\u3088\u308a\u8907\u96d1\u306a\u751f\u304d\u7269\u540c\u69d8\u3001\u9802\u7aef\u53ce\u7e2e\u3068\u3044\u3046\u7d30\u80de\u306e\u5f62\u306e\u5909\u5316\u3092\u4f34\u3044\u307e\u3059\u3002\u3053\u306e\u9802\u7aef\u53ce\u7e2e\u306f26\u7d30\u80de\u671f\u80da\u3067\u8d77\u3053\u308a\u307e\u3059\u3002\u3053\u306e\u6642\u70b9\u3067\u306f\u80da\u306f\u7d30\u80de\u7fa4\u306e\u305f\u3060\u306e\u96c6\u307e\u308a\u3067\u3042\u308a\u3001\u305d\u3053\u306b\u5f62\u614b\u7684\u306a\u8907\u96d1\u3055\u306f\u307b\u307c\u3042\u308a\u307e\u305b\u3093\u3002\u9802\u7aef\u53ce\u7e2e\u304c\u8d77\u3053\u308b\u3068\u3001\u8178\u7d30\u80de\u306e\u5916\u5074\u306e\u8868\u9762\u304c\u7e2e\u307e\u308b\u3053\u3068\u3067\u3001\u8178\u7d30\u80de\u304c\u80da\u306e\u5185\u5074\u306b\u3081\u308a\u8fbc\u3093\u3067\u3044\u304d\u307e\u3059\uff08\u56f3\uff13\uff09\u3002\u3053\u308c\u306b\u4f34\u3063\u3066\u5c06\u6765\u5375\u5b50\u3084\u7cbe\u5b50\u306b\u306a\u308b\u751f\u6b96\u7d30\u80de\u3082\u6298\u308a\u7d19\u306e\u3088\u3046\u306b\u80da\u306e\u5185\u5074\u306b\u3081\u308a\u8fbc\u3093\u3067\u3044\u304f\u4e00\u65b9\u3001\u8868\u76ae\u306b\u306a\u308b\u3088\u3046\u306a\u7d30\u80de\u306f\u80da\u306e\u5916\u5074\u306b\u3068\u3069\u307e\u308a\u307e\u3059\u3002<br>\u3000\u3053\u306e\u3088\u3046\u306b\u3001\u539f\u8178\u9665\u5165\u3067\u306f\u304b\u3089\u3060\u306e\u4e2d\u306b\u6a5f\u80fd\u306e\u7570\u306a\u308b\u7d30\u80de\u306b\u3088\u308b\u5c64\u69cb\u9020\u304c\u3067\u304d\u308b\u306e\u3067\u3059\u3002\u539f\u8178\u9665\u5165\u306e\u306e\u3061\u306b\u3055\u3089\u306b\u8907\u96d1\u306a\u5f62\u3065\u304f\u308a\u3082\u8d77\u3053\u308a\u307e\u3059\u304c\u3001\u3053\u308c\u3089\u3082\u7d30\u80de\u306e\u7269\u7406\u5b66\u7684\u306a\u6027\u8cea\uff08\u5f62\u3001\u52d5\u304d\u3001\u786c\u3055\u306a\u3069\uff09\u3092\u4f53\u8ef8\u306b\u6cbf\u3063\u3066\u5909\u3048\u308b\u3053\u3068\u3067\u30b3\u30f3\u30c8\u30ed\u30fc\u30eb\u3055\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n<\/div>\n\n\n\n<div class=\"wp-block-column is-layout-flow wp-block-column-is-layout-flow\" style=\"flex-basis:50%\"><div class=\"wp-block-image\">\n<figure class=\"aligncenter size-full\"><img decoding=\"async\" width=\"961\" height=\"1130\" src=\"https:\/\/plaza.umin.ac.jp\/wormjp\/wordpress\/wp-content\/uploads\/2025\/01\/2-3_03.jpg\" alt=\"\" class=\"wp-image-404\" srcset=\"https:\/\/plaza.umin.ac.jp\/wormjp\/wordpress\/wp-content\/uploads\/2025\/01\/2-3_03.jpg 961w, https:\/\/plaza.umin.ac.jp\/wormjp\/wordpress\/wp-content\/uploads\/2025\/01\/2-3_03-255x300.jpg 255w, https:\/\/plaza.umin.ac.jp\/wormjp\/wordpress\/wp-content\/uploads\/2025\/01\/2-3_03-871x1024.jpg 871w, https:\/\/plaza.umin.ac.jp\/wormjp\/wordpress\/wp-content\/uploads\/2025\/01\/2-3_03-768x903.jpg 768w, https:\/\/plaza.umin.ac.jp\/wormjp\/wordpress\/wp-content\/uploads\/2025\/01\/2-3_03-670x788.jpg 670w\" sizes=\"(max-width: 961px) 100vw, 961px\" \/><\/figure>\n<\/div><\/div>\n<\/div>\n\n\n\n<p><strong>\u53c2\u8003\u8cc7\u6599<\/strong><br>1\uff09Jonathan Slack\u8457 \u5927\u9688\u5178\u5b50\u3000\u8a33\u3000\u300c\u30a8\u30c3\u30bb\u30f3\u30b7\u30e3\u30eb\u767a\u751f\u751f\u7269\u5b66\u300d, 2002\u5e74\u3000\u7f8a\u571f\u793e<br>2\uff09Gan WJ and Motegi F (2021) Mechanochemical Control of Symmetry Breaking in the&nbsp;<em>Caenorhabditis elegans<\/em>&nbsp;Zygote.&nbsp;<em>Front. Cell Dev. Biol.<\/em>&nbsp;8:619869. doi: 10.3389\/fcell.2020.619869<br>3) Seirin-Lee S., Yamamoto, K., and Kumura A. (2022) <strong>The extra-embryonic space and the local contour are crucial geometric constraints regulating cell arrangement<\/strong> Development. 149(9):dev200401.<\/p>\n\n\n\n<p><strong>\u76e3\u4fee\u8005<\/strong><br>\u6749\u5ca1\u3000\u8ce2\u53f2<br>\u30d6\u30ea\u30c6\u30a3\u30b7\u30e5\u30b3\u30ed\u30f3\u30d3\u30a2\u5927\u5b66\u3067\u7814\u7a76\u5ba4\u3092\u4e3b\u5bb0\u3002\u7dda\u866b\u3092\u7528\u3044\u3066\u521d\u671f\u80da\u767a\u751f\u306e\u7814\u7a76\u3092\u884c\u3063\u3066\u3044\u308b\u3002<\/p>\n\n\n\n<p><strong>\u7814\u7a76\u5ba4HP<\/strong><br><a href=\"https:\/\/www.zoology.ubc.ca\/~sugioka\/\" target=\"_blank\" rel=\"noreferrer noopener\">https:\/\/www.zoology.ubc.ca\/~sugioka\/<\/a><\/p>\n\n\n\n<p class=\"has-text-align-right has-small-font-size\">\u00a92026 \u6749\u5ca1\u8ce2\u53f2\u300c3.\u3000\u7dda\u866b\u304c\u5375\u304b\u3089\u4f53\u306e\u5f62\u3092\u4f5c\u308b\u521d\u671f\u306e\u904e\u7a0b\u2015\u6d41\u308c\u3001\u56de\u8ee2\u3001\u3081\u308a\u8fbc\u307f\u304c\u9375\u3068\u306a\u308b\u30e1\u30ab\u30cb\u30ba\u30e0\u300d<a href=\"https:\/\/creativecommons.org\/licenses\/by\/4.0\/\">CC BY<\/a><\/p>\n\n\n\n<p class=\"has-text-align-right\"><a href=\"#toc_container\" data-type=\"internal\" data-id=\"#toc_container\">\u76ee\u6b21\u30da\u30fc\u30b8\u3078\u2191<\/a><\/p>\n\n\n\n<div style=\"height:20px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n<\/div><\/section>\n\n\n\n<section id=\"section-4\" class=\"wp-block-group\"><div class=\"wp-block-group__inner-container is-layout-constrained wp-block-group-is-layout-constrained\">\n<h3 class=\"wp-block-heading\">4.\u3000\u7d30\u80de\u7cfb\u8b5c\uff08\u4f53\u7d30\u80de\u306e\u904b\u547d\u6c7a\u5b9a\uff09<\/h3>\n\n\n\n<h4 class=\"wp-block-heading\">\u306f\u3058\u3081\u306b<\/h4>\n\n\n\n<p>\u3000\u7dda\u866b\u306e\u53d7\u7cbe\u5375\u304b\u3089\u6210\u866b\u307e\u3067\u306e\u7d30\u80de\u5206\u88c2\u305d\u3057\u3066\u5206\u5316\u306e\u30d1\u30bf\u30fc\u30f3\uff08\u7d30\u80de\u7cfb\u8b5c\uff09\u306f\u3001John Sulston\u3068Robert Horvitz\u3089\u306b\u3088\u3063\u3066\u3001\u76f4\u63a5\u89b3\u5bdf\u306b\u3088\u308a\u6c7a\u5b9a\u3055\u308c\u307e\u3057\u305f (\u56f3\uff11\u306f\u80da\u767a\u751f\u6642\u306e\u7d30\u80de\u7cfb\u8b5c)\u3002\u9a5a\u304f\u3053\u3068\u306b\u7d30\u80de\u7cfb\u8b5c\u306b\u306f\u500b\u4f53\u5dee\u304c\u307b\u3068\u3093\u3069\u3042\u308a\u307e\u305b\u3093\u3002\u7d30\u80de\u304c\u6b7b\u306c\u3068\u3044\u3046\u73fe\u8c61\u3067\u3055\u3048\u3082\u3001\u7279\u5b9a\u306e\u7d30\u80de\u304c\u751f\u307e\u308c\u305f\u76f4\u5f8c\u306b\u6b7b\u306c\u3053\u3068\u304c\u660e\u3089\u304b\u306b\u3055\u308c\u3001\u30d7\u30ed\u30b0\u30e9\u30e0\u7d30\u80de\u6b7b\u3068\u540d\u3065\u3051\u3089\u308c\u307e\u3057\u305f\u3002\u7d30\u80de\u7cfb\u8b5c\u3068\u7d30\u80de\u6b7b\u306e\u30e1\u30ab\u30cb\u30ba\u30e0\u306e\u767a\u898b\u306b\u5bfe\u3057\u30012003\u5e74\u306b\u30ce\u30fc\u30d9\u30eb\u751f\u7406\u5b66\u30fb\u533b\u5b66\u8cde\u304c\u6388\u4e0e\u3055\u308c\u3066\u3044\u307e\u3059\uff08\u53d7\u8cde\u8005\u306fSulston\u3001Horvitz\u304a\u3088\u3073\u7814\u7a76\u3092\u4e3b\u5c0e\u3057\u305fSydney Brenner\uff09\u3002\u7d30\u80de\u7cfb\u8b5c\u306b\u500b\u4f53\u5dee\u304c\u306a\u3044\u306e\u306f\u3001\u5206\u88c2\u3084\u5206\u5316\u304c\u975e\u5e38\u306b\u53b3\u5bc6\u306b\u5236\u5fa1\u3055\u308c\u3066\u3044\u308b\u304b\u3089\u3067\u3059\u3002\u7d30\u80de\u7cfb\u8b5c\u304c\u3069\u306e\u3088\u3046\u306b\u5236\u5fa1\u3055\u308c\u3066\u3044\u308b\u306e\u304b\u3001\u7d39\u4ecb\u3057\u307e\u3059\u3002<\/p>\n\n\n<div class=\"wp-block-image\">\n<figure class=\"aligncenter size-full is-resized\"><img decoding=\"async\" width=\"950\" height=\"510\" src=\"https:\/\/plaza.umin.ac.jp\/wormjp\/wordpress\/wp-content\/uploads\/2025\/02\/6e3de4bf0c4262f5737a198f21e5179d.jpg\" alt=\"\" class=\"wp-image-768\" style=\"width:800px\" srcset=\"https:\/\/plaza.umin.ac.jp\/wormjp\/wordpress\/wp-content\/uploads\/2025\/02\/6e3de4bf0c4262f5737a198f21e5179d.jpg 950w, https:\/\/plaza.umin.ac.jp\/wormjp\/wordpress\/wp-content\/uploads\/2025\/02\/6e3de4bf0c4262f5737a198f21e5179d-300x161.jpg 300w, https:\/\/plaza.umin.ac.jp\/wormjp\/wordpress\/wp-content\/uploads\/2025\/02\/6e3de4bf0c4262f5737a198f21e5179d-768x412.jpg 768w, https:\/\/plaza.umin.ac.jp\/wormjp\/wordpress\/wp-content\/uploads\/2025\/02\/6e3de4bf0c4262f5737a198f21e5179d-670x360.jpg 670w\" sizes=\"(max-width: 950px) 100vw, 950px\" \/><figcaption class=\"wp-element-caption\">\u56f3\uff11\u3000\u80da\u767a\u751f\u306b\u304a\u3051\u308b\u5168\u7d30\u80de\u7cfb\u8b5c<\/figcaption><\/figure>\n<\/div>\n\n\n<p>\u3000\u52d5\u7269\u306e\u4f53\u306b\u306f\u69d8\u3005\u306a\u7a2e\u985e\u306e\u7d30\u80de\u304c\u5b58\u5728\u3057\u307e\u3059\u3002\u767a\u751f\u306e\u969b\u306b\u3001\u53d7\u7cbe\u5375\u3068\u3044\u3046\u3072\u3068\u3064\u306e\u7d30\u80de\u304c\u5206\u88c2\u3059\u308b\u3053\u3068\u3067\u3001\u591a\u7a2e\u591a\u69d8\u306a\u7d30\u80de\u304c\u4f5c\u3089\u308c\u307e\u3059\u304c\u3001\u5206\u88c2\u306b\u3088\u308a\u751f\u3058\u305f\u7d30\u80de\uff08\u5a18\u7d30\u80de\uff09\u304c\u5168\u304f\u540c\u3058\u3067\u3042\u308c\u3070\u3001\u7d30\u80de\u306e\u6570\u306f\u5897\u3048\u3066\u3082\u7a2e\u985e\u306f\u5897\u3048\u307e\u305b\u3093\u3002\u7d30\u80de\u306e\u7a2e\u985e\u3092\u5897\u3084\u3059\u30e1\u30ab\u30cb\u30ba\u30e0\u306f\u5927\u304d\u304f\u5206\u3051\u3066\u4e8c\u7a2e\u985e\u3042\u308a\u307e\u3059\u3002\u4e00\u3064\u306f\u3001\u7d30\u80de\u304c\u5916\u90e8\u306e\u74b0\u5883\uff08\u96a3\u63a5\u7d30\u80de\u3068\u306e\u63a5\u89e6\u3084\u3001\u30b7\u30b0\u30ca\u30eb\u5206\u5b50\u306e\u53d7\u5bb9\u306a\u3069\uff09\u304c\u5a18\u7d30\u80de\u9593\u3067\u7570\u306a\u308b\u305f\u3081\u3001\u5a18\u7d30\u80de\u304c\u7570\u306a\u308b\u6027\u8cea\uff08\u7d30\u80de\u904b\u547d\u3068\u547c\u3076\uff09\u3092\u7372\u5f97\u3057\u307e\u3059\uff08\u6a5f\u69cb\u2460\uff09\u3002\u3082\u3046\u4e00\u3064\u306f\u3001\u5a18\u7d30\u80de\u304c\u751f\u307e\u308c\u308b\u3068\u304d\u306b\u3001\u7570\u306a\u308b\u7269\u8cea\u3092\u6bcd\u7d30\u80de\u304b\u3089\u53d7\u3051\u7d99\u3050\u305f\u3081\u306b\u3001\u7570\u306a\u308b\u7d30\u80de\u904b\u547d\u3092\u7372\u5f97\u3059\u308b\u5834\u5408\u3067\u3001\u975e\u5bfe\u79f0\u5206\u88c2\u3068\u547c\u3070\u308c\u307e\u3059\uff08\u6a5f\u69cb\u2461\uff09\u3002\u7dda\u866b\u306e\u767a\u751f\u3067\u306f\u3053\u308c\u3092\u7d44\u307f\u5408\u308f\u305b\u3066\u591a\u69d8\u306a\u7d30\u80de\u3092\u4f5c\u3063\u3066\u3044\u304d\u307e\u3059\u3002<\/p>\n\n\n<div class=\"wp-block-image\">\n<figure class=\"aligncenter size-full is-resized\"><img decoding=\"async\" width=\"1314\" height=\"565\" src=\"https:\/\/plaza.umin.ac.jp\/wormjp\/wordpress\/wp-content\/uploads\/2025\/01\/2-4_01.png\" alt=\"\" class=\"wp-image-412\" style=\"width:800px\" srcset=\"https:\/\/plaza.umin.ac.jp\/wormjp\/wordpress\/wp-content\/uploads\/2025\/01\/2-4_01.png 1314w, https:\/\/plaza.umin.ac.jp\/wormjp\/wordpress\/wp-content\/uploads\/2025\/01\/2-4_01-300x129.png 300w, https:\/\/plaza.umin.ac.jp\/wormjp\/wordpress\/wp-content\/uploads\/2025\/01\/2-4_01-1024x440.png 1024w, https:\/\/plaza.umin.ac.jp\/wormjp\/wordpress\/wp-content\/uploads\/2025\/01\/2-4_01-768x330.png 768w, https:\/\/plaza.umin.ac.jp\/wormjp\/wordpress\/wp-content\/uploads\/2025\/01\/2-4_01-670x288.png 670w\" sizes=\"(max-width: 1314px) 100vw, 1314px\" \/><figcaption class=\"wp-element-caption\">\u56f3\uff12<br>\u5de6\uff1a\u767a\u751f\u521d\u671f\u306e\u7d30\u80de\u7cfb\u8b5c\uff08\u7d30\u80de\u5206\u88c2\u30d1\u30bf\u30fc\u30f3\u3068\u7d30\u80de\u904b\u547d\uff09\u3002\u5206\u88c2\u3054\u3068\u306b\u5a18\u7d30\u80de\u306f\u7570\u306a\u308b\u904b\u547d\u3092\u7372\u5f97\u3059\u308b\u3002\u305d\u308c\u305e\u308c\u306e\u7d30\u80de\u304c\u305d\u306e\u5f8c\u4f5c\u308a\u51fa\u3059\u4e3b\u306a\u7d30\u80de\u7a2e\u3092\u793a\u3057\u307e\u3059\u3002<br>\u53f3\uff1a\uff14\u7d30\u80de\u671f\u306e\u7d30\u80de\u9593\u30b7\u30b0\u30ca\u30eb\u3002P2\u304b\u3089ABp\u3078\u306e\u30b7\u30b0\u30ca\u30eb\u306fNotch\u53d7\u5bb9\u4f53\u3092\u4ecb\u3057\u3066\uff08\u8d64\uff09\u3001ABp\u306e\u904b\u547d\u306e\u9055\u3044\u3092\u4f5c\u308a\u51fa\u3057\u307e\u3059\uff08\u6a5f\u69cb\u2460\uff09\u3002P2\u304b\u3089EMS\u3078\u306eWnt\u30b7\u30b0\u30ca\u30eb\uff08\u7d2b\uff09\u306f\u3001EMS\u7d30\u80de\u5185\u306b\u6975\u6027\u3092\u4f5c\u308a\u51fa\u3057\u3001\u305d\u306e\u5a18\u7d30\u80de\u304c\u7570\u306a\u308b\u904b\u547d\u306b\u306a\u308a\u307e\u3059\uff08\u6a5f\u69cb\u2461\uff09\u3002<\/figcaption><\/figure>\n<\/div>\n\n\n<h4 class=\"wp-block-heading\">\u80da\u767a\u751f\u306e\u7d30\u80de\u7cfb\u8b5c\u5236\u5fa1<\/h4>\n\n\n\n<p>\u3000\u9805\u76ee\u300c\u521d\u671f\u767a\u751f\u300d\u3067\u89e6\u308c\u305f\u3088\u3046\u306b\u3001\u53d7\u7cbe\u5375(P0\u7d30\u80de)\u306e\u521d\u3081\u306e\u5206\u88c2\u306f\u975e\u5bfe\u79f0\u3067\uff08\u6a5f\u69cb\u2461\uff09\u3001\u4f53\u7d30\u80de\u3092\u4f5c\u308bAB\u3068\u751f\u6b96\u7d30\u80de\u306a\u3069\u3092\u4f5c\u308bP1\u7d30\u80de\u304c\u3067\u304d\u307e\u3059\uff08\u56f3\uff12\u5de6\uff09\u3002P1\u304a\u3088\u3073\u305d\u306e\u5b50\u5b6b\u306e\u751f\u6b96\u7d30\u80de\u3092\u4f5c\u308b\u7d30\u80de\uff08P\u7cfb\u5217\u7d30\u80de\uff09\u306f\u3001\u540c\u3058\u6a5f\u69cb\u306b\u3088\u308a\u3001\u975e\u5bfe\u79f0\u5206\u88c2\u3092\u7e70\u308a\u8fd4\u3057\u3001\u4f53\u7d30\u80de\uff08EMS\u7d30\u80de\u306a\u3069\uff09\u3068\u751f\u6b96\u7d30\u80de\u3092\u4f5c\u308a\u51fa\u3057\u307e\u3059\u3002AB\u7d30\u80de\u306e\u5a18\u7d30\u80de\u306f\u3001\u751f\u307e\u308c\u305f\u3068\u304d\u306b\u306f\u540c\u3058\u6027\u8cea\u3067\u3059\u304c\u3001ABp\u7d30\u80de\u3060\u3051\u304c\u3001\u96a3\u63a5\u7d30\u80deP2\u304b\u3089\u306e\u30b7\u30b0\u30ca\u30eb\uff08Notch\u53d7\u5bb9\u4f53\u306e\u30ea\u30ac\u30f3\u30c9\uff09\u3092\u53d7\u5bb9\u3059\u308b\u305f\u3081\uff08\u6a5f\u69cb\u2460\uff09\u3001ABa\u7d30\u80de\u3068\u7570\u306a\u308b\u904b\u547d\u3092\u7372\u5f97\u3057\u307e\u3059\uff08\u56f3\uff12\u53f3\uff09\u3002\u6b21\u306bEMS\u7d30\u80de\u304c\u5206\u88c2\u3057\u3001\u7b4b\u8089\u306a\u3069\u3092\u4f5c\u308bMS\u7d30\u80de\u3068\u3001\u8178\u3092\u4f5c\u308bE\u7d30\u80de\u304c\u4f5c\u3089\u308c\u307e\u3059\u3002MS\u3068E\u7d30\u80de\u306f\u751f\u307e\u308c\u305f\u3068\u304d\u304b\u3089\u7570\u306a\u3063\u3066\u304a\u308a\uff08\u6a5f\u69cb\u2461\uff09\u3001\u3070\u3089\u3070\u3089\u306b\u3057\u3066\u3082\u3001\u305d\u308c\u305e\u308c\u7b4b\u8089\u3068\u8178\u3092\u4f5c\u308a\u307e\u3059\u3002\u3053\u306e\u975e\u5bfe\u79f0\u5206\u88c2\u306f\u3001Wnt\u30b7\u30b0\u30ca\u30eb\u4f1d\u9054\u7d4c\u8def\u306e\u50cd\u304d\u306b\u3088\u308a\u3001\u5206\u88c2\u5f8c\u3001\u30b7\u30b0\u30ca\u30eb\u5206\u5b50\u03b2\u30ab\u30c6\u30cb\u30f3\u3084\u8ee2\u5199\u56e0\u5b50TCF\u306e\u6838\u5185\u6fc3\u5ea6\u304c\u5a18\u7d30\u80de\u9593\u3067\u7570\u306a\u3063\u3066\u304a\u308a\u3001\u3053\u308c\u306b\u3088\u308a\u5a18\u7d30\u80de\u306f\u7570\u306a\u308b\u7d30\u80de\u306b\u306a\u308a\u307e\u3059\u3002\u3053\u306e\u975e\u5bfe\u79f0\u6027\u306f\u7d30\u80de\u5916\u306e\u30b7\u30b0\u30ca\u30eb\u5206\u5b50Wnt\u306b\u3088\u3063\u3066\u5236\u5fa1\u3055\u308c\u3066\u3044\u307e\u3059\u304c\u3001\u3053\u306e\u30b7\u30b0\u30ca\u30eb\u306f\u6a5f\u69cb\u2460\u306e\u3088\u3046\u306b\u5a18\u7d30\u80de\u306b\u50cd\u3044\u3066\u3001\u9055\u3044\u3092\u8a98\u5c0e\u3059\u308b\u306e\u3067\u306f\u306a\u304f\u3001\u6bcd\u7d30\u80de\u306b\u50cd\u3044\u3066\u3001\u305d\u306e\u5185\u90e8\u306b\u30b7\u30b0\u30ca\u30eb\u5206\u5b50\u306e\u504f\u308a\uff08\u6975\u6027\uff09\u3092\u4f5c\u308b\u3053\u3068\u3067\u3001\u5a18\u7d30\u80de\u306e\u9055\u3044\u3092\u4f5c\u308a\u307e\u3059\uff08\u56f3\uff12\u53f3\uff09\u3002<\/p>\n\n\n\n<p>\u3000\u305d\u306e\u5f8c\u3001\u307b\u3068\u3093\u3069\u306e\u4f53\u7d30\u80de\u306e\u5206\u88c2\u3067TCF\u8ee2\u5199\u56e0\u5b50\u306e\u975e\u5bfe\u79f0\u6838\u5c40\u5728\u304c\u89b3\u5bdf\u3055\u308c\u3001\u975e\u5bfe\u79f0\u5206\u88c2\uff08\u6a5f\u69cb\u2461\uff09\u3092\u7e70\u308a\u8fd4\u3059\u3053\u3068\u3067\u3001\u7570\u306a\u308b\u5a18\u7d30\u80de\u304c\u4f5c\u3089\u308c\u3066\u3044\u304d\u307e\u3059\u3002\u52a0\u3048\u3066\u3001\u3044\u304f\u3064\u304b\u306e\u5a18\u7d30\u80de\u306b\u3001ABp\u7d30\u80de\u904b\u547d\u3092\u5236\u5fa1\u3057\u305f\u306e\u3068\u540c\u69d8\u3001\u96a3\u63a5\u7d30\u80de\u3068\u306e\u63a5\u89e6\u3092\u4ecb\u3057\u305fNotch\u30b7\u30b0\u30ca\u30eb\u304c\u50cd\u304d\u3001\u7279\u7570\u7684\u306a\u7d30\u80de\u904b\u547d\u3092\u8a98\u5c0e\u3057\u307e\u3059\uff08\u6a5f\u69cb\u2460\uff09\u3002\u3053\u306e\u3088\u3046\u306b\u3001\u4f53\u7d30\u80de\u306e\u591a\u69d8\u306a\u904b\u547d\u306f\u6a5f\u69cb\u2460\u3068\u2461\u306e\u7d44\u307f\u5408\u308f\u305b\u3067\u6c7a\u5b9a\u3055\u308c\u3066\u3044\u304d\u307e\u3059\u3002<\/p>\n\n\n\n<div class=\"wp-block-columns is-layout-flex wp-container-core-columns-is-layout-9d6595d7 wp-block-columns-is-layout-flex\">\n<div class=\"wp-block-column is-layout-flow wp-block-column-is-layout-flow\" style=\"flex-basis:50%\">\n<h4 class=\"wp-block-heading\">\u5e7c\u866b\u306e\u7d30\u80de\u7cfb\u8b5c\u5236\u5fa1<\/h4>\n\n\n\n<p>\u3000\u5375\u304b\u3089\u5b75\u5316\u3057\u305f\u5e7c\u866b\u306f\u751f\u5b58\u306b\u5fc5\u8981\u306a\u7d30\u80de\u306f\u3059\u3067\u306b\u6301\u3063\u3066\u3044\u307e\u3059\u3002\u5e7c\u866b\u671f\u3067\u306f\u3001\u4f53\u306e\u6210\u9577\u306b\u4f34\u3046\u7d30\u80de\u306e\u88dc\u5145\u3068\u751f\u6b96\u5668\u5b98\u306e\u5f62\u6210\u306b\u5fc5\u8981\u306a\u7d30\u80de\u5206\u88c2\u304c\u8d77\u3053\u308a\u307e\u3059\u3002\u3053\u308c\u3089\u306e\u7d30\u80de\u5206\u88c2\u3082\u307b\u3068\u3093\u3069\u304cWnt\u30b7\u30b0\u30ca\u30eb\u306b\u5236\u5fa1\u3055\u308c\u305f\u975e\u5bfe\u79f0\u5206\u88c2\uff08\u6a5f\u69cb\u2461\uff09\u3067\u3001\u5a18\u7d30\u80de\u306f\u7570\u306a\u308b\u904b\u547d\u3092\u7372\u5f97\u3057\u307e\u3059\u3002\u4e00\u65b9\u3001\u7d30\u80de\u5916\u30b7\u30b0\u30ca\u30eb\u306b\u3088\u308b\u7d30\u80de\u904b\u547d\u5236\u5fa1\uff08\u6a5f\u69cb\u2460\uff09\u3082\u50cd\u3044\u3066\u304a\u308a\u3001\u305d\u306e\u4ee3\u8868\u7684\u306a\u9670\u9580\u5f62\u6210\u306b\u3064\u3044\u3066\u7d39\u4ecb\u3057\u307e\u3059\uff08\u56f3\uff13\uff09\u3002\u9670\u9580\uff08\u7523\u5375\u53e3\uff09\u306f\u3001L3\u5e7c\u866b\u671f\u306b\uff16\u3064\u306e\u524d\u99c6\u7d30\u80de\u306e\u3046\u3061\uff13\u3064\uff08P5.p\u3001P6.p\u3001P7.p\uff09\u304b\u3089\u4f5c\u3089\u308c\u307e\u3059\u3002P6.p\u306b\u8fd1\u63a5\u3059\u308b\u30a2\u30f3\u30ab\u30fc\u7d30\u80de\u304b\u3089\u5206\u6ccc\u3055\u308c\u308b\u30b7\u30b0\u30ca\u30eb\u5206\u5b50\u306b\u3088\u3063\u3066\u3001\u7d30\u80de\u5185\u3067Ras-Map\u30ad\u30ca\u30fc\u30bc\u7d4c\u8def\u304c\u6d3b\u6027\u5316\u3055\u308c\u3001\u30a2\u30f3\u30ab\u30fc\u7d30\u80de\u306b\u6700\u3082\u8fd1\u63a5\u3059\u308bP6.p\u7d30\u80de\u306f1\u309c\u3001\u5c11\u3057\u96e2\u308c\u305fP5.p\u3068P7.p\u7d30\u80de\u306f2\u309c\u3068\u547c\u3070\u308c\u308b\u7d30\u80de\u904b\u547d\u3092\u7372\u5f97\u3057\u307e\u3059\u3002\u52a0\u3048\u3066\u3002\uff11\u309c\u3068\uff12\u309c\u306e\u9055\u3044\u306b\u306f\u3001\u8fd1\u63a5\u7d30\u80de\u9593\u306eNotch\u53d7\u5bb9\u4f53\u3092\u4ecb\u3057\u305f\u30b7\u30b0\u30ca\u30eb\u3082\u95a2\u4e0e\u3057\u3066\u304a\u308a\u3001\u3053\u306e\u4e8c\u7a2e\u306e\u30b7\u30b0\u30ca\u30eb\u6a5f\u69cb\u306e\u7d44\u307f\u5408\u308f\u305b\u3067\u3001\uff12\u309c\uff11\u309c\uff12\u309c\u3068\u3044\u3046\u93e1\u50cf\u5bfe\u79f0\u306a\u7d30\u80de\u7cfb\u8b5c\u3001\u305d\u3057\u3066\u93e1\u50cf\u5bfe\u79f0\u306a\u9670\u9580\u306e\u5f62\u614b\u304c\u4f5c\u3089\u308c\u307e\u3059\u3002<\/p>\n<\/div>\n\n\n\n<div class=\"wp-block-column sp_box_ord_01 is-layout-flow wp-block-column-is-layout-flow\" style=\"flex-basis:50%\"><div class=\"wp-block-image\">\n<figure class=\"aligncenter size-full\"><img decoding=\"async\" width=\"615\" height=\"345\" src=\"https:\/\/plaza.umin.ac.jp\/wormjp\/wordpress\/wp-content\/uploads\/2025\/01\/2-4_02.png\" alt=\"\" class=\"wp-image-413\" style=\"object-fit:cover\" srcset=\"https:\/\/plaza.umin.ac.jp\/wormjp\/wordpress\/wp-content\/uploads\/2025\/01\/2-4_02.png 615w, https:\/\/plaza.umin.ac.jp\/wormjp\/wordpress\/wp-content\/uploads\/2025\/01\/2-4_02-300x168.png 300w\" sizes=\"(max-width: 615px) 100vw, 615px\" \/><figcaption class=\"wp-element-caption\">\u56f33<br>\u9670\u9580\u767a\u751f\u306e\u969b\u306e\u7d30\u80de\u9593\u30b7\u30b0\u30ca\u30eb\u3002\u30a2\u30f3\u30ab\u30fc\u7d30\u80de\uff08AC\uff09\u304b\u3089\u306e\u30b7\u30b0\u30ca\u30eb\uff08\u7d2b\uff09\u3092\u5f37\u304f\u53d7\u3051\u308bP6.p\u7d30\u80de\u306f\uff11\u309c\u3001\u5f31\u304f\u53d7\u3051\u308bP5.p\u3001P7.p\u7d30\u80de\u304c2\u309c\u306e\u904b\u547d\u3092\u7372\u5f97\u3057\u307e\u3059\u3002\u96a3\u63a5\u7d30\u80de\u9593\u306eNotch\u53d7\u5bb9\u4f53\u3092\u4ecb\u3057\u305f\u30b7\u30b0\u30ca\u30eb\uff08\u8d64\uff09\u30822\u309c\u904b\u547d\u3092\u8a98\u5c0e\u3057\u307e\u3059\u3002<\/figcaption><\/figure>\n<\/div><\/div>\n<\/div>\n\n\n\n<h4 class=\"wp-block-heading\">\u7d42\u308f\u308a\u306b<\/h4>\n\n\n\n<p>\u3000\u3053\u306e\u3088\u3046\u306b\u7dda\u866b\u306e\u767a\u751f\u3067\u306f\u3001\u6a5f\u69cb\u2460\u2461\u306e\u7d44\u307f\u5408\u308f\u305b\u306b\u3088\u308a\u3001\u53b3\u5bc6\u306b\u7d30\u80de\u904b\u547d\u304c\u5236\u5fa1\u3055\u308c\u3066\u3044\u307e\u3059\u3002\u3053\u306e\u305f\u3081\u3001\u767a\u751f\u306e\u9014\u4e2d\u306e\u500b\u3005\u306e\u7d30\u80de\u304c\u3001\u3069\u306e\u3088\u3046\u306b\u751f\u3058\u305f\u306e\u304b\u3001\u3053\u308c\u304b\u3089\u3069\u306e\u3088\u3046\u306a\u7d30\u80de\u3092\u4f5c\u308b\u306e\u304b\u304c\u308f\u304b\u308a\u307e\u3059\u3002\u69d8\u3005\u306a\u5909\u7570\u4f53\u3084\u907a\u4f1d\u5b50\u64cd\u4f5c\u3067\u3001\u904b\u547d\u306b\u5909\u5316\u304c\u8d77\u3053\u308c\u3070\u3001\u305d\u306e\u539f\u56e0\u3092\u9061\u3063\u3066\u8abf\u3079\u308b\u3053\u3068\u304c\u3067\u304d\u307e\u3059\u3002\u305d\u3057\u3066\u3001\u7570\u5e38\u304c\u8d77\u3053\u308b\u969b\u306e\u3001\u907a\u4f1d\u5b50\u767a\u73fe\u3001\u5206\u5b50\u306e\u6a5f\u80fd\u30fb\u5c40\u5728\u306e\u5909\u5316\u3092\u8abf\u3079\u308b\u3053\u3068\u3067\u3001\u3069\u306e\u3088\u3046\u306b\u7d30\u80de\u904b\u547d\u30fb\u7d30\u80de\u7cfb\u8b5c\u304c\u6c7a\u3081\u3089\u308c\u308b\u306e\u304b\u3092\u77e5\u308b\u3053\u3068\u304c\u3067\u304d\u307e\u3059\u3002<\/p>\n\n\n\n<p><strong>\u76e3\u4fee\u8005<\/strong><br>\u6fa4\u3000\u6589\u3000<br>\u5927\u962a\u751f\u307e\u308c\u3002\u4eac\u90fd\u5927\u5b66\u5927\u5b66\u9662\u535a\u58eb\u8ab2\u7a0b\u4fee\u4e86\u3002\u73fe\u5728\u3001\u907a\u4f1d\u5b66\u7814\u7a76\u6240\u6559\u6388\u3068\u3057\u3066\u300c\u767a\u751f\u306e\u4ed5\u7d44\u307f\u300d\u306e\u7814\u7a76\u30fb\u8b1b\u7fa9\u3092\u62c5\u5f53\u3057\u3066\u3044\u308b\u3002\u65e5\u672c\u767a\u751f\u751f\u7269\u5b66\u4f1a\u7406\u4e8b\u306a\u3069\u3082\u52d9\u3081\u305f\u3002<\/p>\n\n\n\n<p><strong>\u7814\u7a76\u5ba4HP<\/strong><br><a href=\"http:\/\/square.umin.ac.jp\/Nemalab\/Home.html\">http:\/\/square.umin.ac.jp\/Nemalab\/Home.html<\/a><\/p>\n\n\n\n<p class=\"has-text-align-right has-small-font-size\">\u00a92026 \u866b\u306e\u96c6\u3044\uff08\u7dda\u866b\u7814\u7a76\u8005\u30b3\u30df\u30e5\u30cb\u30c6\u30a3\uff09\u300c4.\u3000\u7d30\u80de\u7cfb\u8b5c\uff08\u4f53\u7d30\u80de\u306e\u904b\u547d\u6c7a\u5b9a\uff09\u300d<a href=\"https:\/\/creativecommons.org\/licenses\/by\/4.0\/\">CC BY<\/a><\/p>\n\n\n\n<p class=\"has-text-align-right\"><a href=\"#toc_container\" data-type=\"internal\" data-id=\"#toc_container\">\u76ee\u6b21\u30da\u30fc\u30b8\u3078\u2191<\/a><\/p>\n\n\n\n<div style=\"height:20px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n<\/div><\/section>\n\n\n\n<section id=\"section-5\" class=\"wp-block-group\"><div class=\"wp-block-group__inner-container is-layout-constrained wp-block-group-is-layout-constrained\">\n<h3 class=\"wp-block-heading\">5.\u3000\u5f62\u614b\u5f62\u6210\u30fb\u5668\u5b98\u5f62\u6210<\/h3>\n\n\n\n<p>\u3000<em>C. elegans<\/em>\u306e\u304b\u3089\u3060\u306e\u4e00\u756a\u8868\u9762\u306f\u5916\u9aa8\u683c\u3067\u3042\u308b\u30ad\u30e5\u30fc\u30c6\u30a3\u30af\u30eb\uff08\u7d30\u80de\u5916\u30de\u30c8\u30ea\u30c3\u30af\u30b9\uff09\u304c\u3042\u308a\u3001\u305d\u306e\u5185\u5074\u306b\u8868\u76ae\u3068\u4f53\u58c1\u7b4b\u306e\u5c64\u304c\u3042\u308a\u307e\u3059\u3002\u307b\u3068\u3093\u3069\u306e\u795e\u7d4c\u7d30\u80de\u306f\u8868\u76ae\u306e\u5185\u9762\u306b\u4ed8\u7740\u3057\u3066\u5b58\u5728\u3057\u3066\u3044\u307e\u3059\u3002\u3055\u3089\u306b\u305d\u306e\u5185\u5074\u306f\u507d\u4f53\u8154\u3068\u547c\u3070\u308c\u3066\u304a\u308a\u3001\u3053\u3053\u306b\u306f\u54bd\u982d\u3001\u6d88\u5316\u7ba1\u3001\u751f\u6b96\u5de3\u306e3\u7a2e\u985e\u306e\u5668\u5b98\u304c\u5b58\u5728\u3057\u3066\u3044\u307e\u3059\u3002\u54bd\u982d\u306f\u30d2\u30c8\u306e\u5834\u5408\u306e\u53e3\u3068\u5589\u3001\u6d88\u5316\u7ba1\u306f\u80c3\u3084\u8178\u3001\u751f\u6b96\u5de3\u306f\u5375\u5de3\u3084\u7cbe\u5de3\u306b\u3042\u305f\u308a\u307e\u3059\u3002\u52d5\u7269\u306e\u591a\u304f\u306e\u5668\u5b98\u306f\u4e0a\u76ae\u3068\u547c\u3070\u308c\u308b\u4e00\u5c64\u306e\u7d30\u80de\u5c64\u306b\u8986\u308f\u308c\u3066\u304a\u308a\u3001\u3055\u3089\u306b\u4e0a\u76ae\u306e\u8868\u9762\u306f\u57fa\u5e95\u819c\u3068\u547c\u3070\u308c\u308b\u7d30\u80de\u5916\u30de\u30c8\u30ea\u30c3\u30af\u30b9\u306b\u8986\u308f\u308c\u3066\u3044\u307e\u3059\u3002\u52d5\u7269\u306e\u767a\u751f\u904e\u7a0b\u3067\u306f\u69d8\u3005\u306a\u7d44\u7e54\u30fb\u5668\u5b98\u306e\u5f62\u614b\u5f62\u6210\u304c\u9032\u884c\u3057\u307e\u3059\u3002\u5f62\u614b\u5f62\u6210\u306e\u4e3b\u306a\u8981\u56e0\u3068\u306a\u308b\u306e\u306f\u7d30\u80de\u306e\u5206\u88c2\u3001\u5206\u5316\u3001\u79fb\u52d5\u3001\u5f62\u614b\u5909\u5316\u3001\u57fa\u5e95\u819c\u306e\u5f62\u6210\u3001\u7d30\u80de\u9593\u63a5\u7740\u306e\u5909\u5316\u3001\u7d30\u80de\u57fa\u5e95\u819c\u9593\u63a5\u7740\u306e\u5909\u5316\u306a\u3069\u304c\u3042\u3052\u3089\u308c\u307e\u3059\u3002\u3053\u3053\u3067\u306f\u751f\u6b96\u5de3\u306e\u5f62\u6210\u3092\u4e2d\u5fc3\u3068\u3057\u3066\u3001\u5668\u5b98\u5f62\u6210\u306e\u3057\u304f\u307f\u3092\u89e3\u8aac\u3057\u307e\u3059\u3002<\/p>\n\n\n\n<div class=\"wp-block-columns is-layout-flex wp-container-core-columns-is-layout-9d6595d7 wp-block-columns-is-layout-flex\">\n<div class=\"wp-block-column is-layout-flow wp-block-column-is-layout-flow\" style=\"flex-basis:50%\">\n<h4 class=\"wp-block-heading\">\u751f\u6b96\u5de3\u306e\u5f62\u6210<\/h4>\n\n\n\n<p>\u3000<em>C. elegans<\/em>\u306f\u304b\u3089\u3060\u306e\u4e2d\u5fc3\u304b\u3089\u524d\u5f8c\u306bU\u5b57\u578b\u306b\u4f38\u3073\u305f\u30c1\u30e5\u30fc\u30d6\u72b6\u306e\u751f\u6b96\u5de3\u3092\u6301\u3063\u3066\u3044\u307e\u3059\u3002\u5b75\u5316\u76f4\u5f8c\u306e1\u9f62\u5e7c\u866b\u306e\u8179\u90e8\u4e2d\u592e\u306b\u3001\u524d\u5f8c\u65b9\u5411\u306b4\u500b\u306e\u7d30\u80de\u304c\u4e26\u3073\u57fa\u5e95\u819c\u3067\u8986\u308f\u308c\u305f\u751f\u6b96\u5de3\u539f\u57fa\u304c\u5b58\u5728\u3057\u307e\u3059\u3002\u3053\u306e\u3046\u3061\u3001\u4e2d\u592e\u306e2\u500b\u306e\u7d30\u80deZ3\u3068Z3\u306f\u59cb\u539f\u751f\u6b96\u7d30\u80de\u3067\u3001\u5206\u88c2\u3092\u7e70\u308a\u8fd4\u3057\u3001\u6210\u866b\u671f\u306b\u306f\u7cbe\u5b50\u3084\u5375\u306b\u5206\u5316\u3057\u307e\u3059\u3002\u4e21\u7aef\u306e2\u500b\u306e\u7d30\u80deZ1\u3068Z4\u306f\u540c\u3058\u6c7a\u307e\u3063\u305f\u30d1\u30bf\u30fc\u30f3\u3067\u5206\u88c2\u3092\u884c\u3044\u3001\u305d\u308c\u305e\u308c\u304c\u524d\u5074\u3068\u5f8c\u308d\u5074\u306e\u751f\u6b96\u5de3\u306e\u9798\u3092\u3064\u304f\u308b10\u500b\u306e\u7d30\u80de\u30681\u500b\u306e\u5148\u7aef\u7d30\u80deDTC\u306b\u5206\u5316\u3057\u307e\u3059\u3002DTC\u306f1\u9f62\u5e7c\u866b\u671f\u306bZ1\u3068Z4\u306e2\u56de\u76ee\u306e\u5206\u88c2\u3067\u751f\u3058\u30014\u9f62\u5e7c\u866b\u671f\u307e\u3067\u306e\u9593\u306bU\u5b57\u578b\u306e\u79fb\u52d5\u3092\u884c\u3046\u3053\u3068\u306b\u3088\u308a\u3001U\u5b57\u578b\u306e\u751f\u6b96\u5de3\u306e\u5f62\u6210\u306e\u6307\u63ee\u3092\u3068\u308b\u50cd\u304d\u3092\u3057\u307e\u3059\uff08\u56f3\uff11\uff09\u3002\u3053\u306e\u3088\u3046\u306a\u30c1\u30e5\u30fc\u30d6\u72b6\u306e\u5668\u5b98\u306f\u7dda\u866b\u72ec\u7279\u306e\u3082\u306e\u3067\u306f\u306a\u304f\u3001\u54fa\u4e73\u985e\u3067\u8a00\u3048\u3070\u3001\u80ba\u3084\u814e\u81d3\u3001\u809d\u81d3\u3001\u4e73\u817a\u3001\u553e\u6db2\u817a\u306a\u3069\u591a\u304f\u306e\u5668\u5b98\u306f\u8907\u96d1\u306b\u679d\u5206\u304b\u308c\u3057\u305f\u4e0a\u76ae\u30c1\u30e5\u30fc\u30d6\u3067\u3067\u304d\u3066\u3044\u307e\u3059\u3002\u3053\u308c\u3089\u306e\u5668\u5b98\u306f\u54fa\u4e73\u985e\u306e\u767a\u751f\u306e\u904e\u7a0b\u3067\u3001\u5358\u7d14\u306a\u30c1\u30e5\u30fc\u30d6\u304c\u4f38\u9577\u3068\u679d\u5206\u304b\u308c\u3092\u7e70\u308a\u8fd4\u3059\u3053\u3068\u306b\u3088\u308a\u5f62\u6210\u3055\u308c\u307e\u3059\u3002<\/p>\n<\/div>\n\n\n\n<div class=\"wp-block-column is-layout-flow wp-block-column-is-layout-flow\" style=\"flex-basis:50%\"><div class=\"wp-block-image\">\n<figure class=\"aligncenter size-full\"><img decoding=\"async\" width=\"538\" height=\"672\" src=\"https:\/\/plaza.umin.ac.jp\/wormjp\/wordpress\/wp-content\/uploads\/2025\/01\/2-5_01.png\" alt=\"\" class=\"wp-image-426\" srcset=\"https:\/\/plaza.umin.ac.jp\/wormjp\/wordpress\/wp-content\/uploads\/2025\/01\/2-5_01.png 538w, https:\/\/plaza.umin.ac.jp\/wormjp\/wordpress\/wp-content\/uploads\/2025\/01\/2-5_01-240x300.png 240w\" sizes=\"(max-width: 538px) 100vw, 538px\" \/><\/figure>\n<\/div><\/div>\n<\/div>\n\n\n\n<div class=\"wp-block-columns is-layout-flex wp-container-core-columns-is-layout-9d6595d7 wp-block-columns-is-layout-flex\">\n<div class=\"wp-block-column sp_box_ord_01 is-layout-flow wp-block-column-is-layout-flow\" style=\"flex-basis:50%\"><div class=\"wp-block-image\">\n<figure class=\"aligncenter size-full\"><img decoding=\"async\" width=\"676\" height=\"338\" src=\"https:\/\/plaza.umin.ac.jp\/wormjp\/wordpress\/wp-content\/uploads\/2025\/01\/2-5_02-e1736484680696.png\" alt=\"\" class=\"wp-image-427\" srcset=\"https:\/\/plaza.umin.ac.jp\/wormjp\/wordpress\/wp-content\/uploads\/2025\/01\/2-5_02-e1736484680696.png 676w, https:\/\/plaza.umin.ac.jp\/wormjp\/wordpress\/wp-content\/uploads\/2025\/01\/2-5_02-e1736484680696-300x150.png 300w, https:\/\/plaza.umin.ac.jp\/wormjp\/wordpress\/wp-content\/uploads\/2025\/01\/2-5_02-e1736484680696-670x335.png 670w\" sizes=\"(max-width: 676px) 100vw, 676px\" \/><\/figure>\n<\/div><\/div>\n\n\n\n<div class=\"wp-block-column is-layout-flow wp-block-column-is-layout-flow\" style=\"flex-basis:50%\">\n<h4 class=\"wp-block-heading\">\u5148\u7aef\u7d30\u80de\u306e\u79fb\u52d5\u306e\u3057\u304f\u307f<\/h4>\n\n\n\n<p>\u3000\u3067\u306fDTC\u306f\u3069\u306e\u3088\u3046\u306b\u3057\u3066\u79fb\u52d5\u3092\u884c\u3046\u306e\u3067\u3057\u3087\u3046\u304b\u3002\u4e0a\u306b\u8ff0\u3079\u305f\u3088\u3046\u306b\u751f\u6b96\u5de3\u306e\u8868\u9762\u306f\u57fa\u5e95\u819c\u3067\u8986\u308f\u308c\u3066\u3044\u307e\u3059\u3002DTC\u304c\u79fb\u52d5\u3092\u884c\u3046\u6642\u306b\u306f\u3001DTC\u306f\u57fa\u5e95\u819c\u306b\u63a5\u7740\u3057\u3066\u304a\u308a\u3001\u3053\u308c\u3092\u30a2\u30af\u30c1\u30f3\u30d5\u30a3\u30e9\u30e1\u30f3\u30c8\u306a\u3069\u306e\u7d30\u80de\u9aa8\u683c\u306e\u529b\u3067\u62bc\u3057\u5e83\u3052\u308b\u3088\u3046\u306b\u3057\u3066\u79fb\u52d5\u3057\u3066\u3044\u304d\u307e\u3059\u3002\u3053\u306e\u6642\u3001\u751f\u6b96\u5de3\u306e\u5148\u7aef\u90e8\u5206\u306b\u306f\u65b0\u3057\u3044\u57fa\u5e95\u819c\u304c\u3069\u3093\u3069\u3093\u4ed8\u52a0\u3055\u308c\u3066\u3044\u304d\u307e\u3059\u3002\u57fa\u5e95\u819c\u306e\u4e3b\u6210\u5206\u306f\u30b3\u30e9\u30fc\u30b2\u30f3\u3068\u547c\u3070\u308c\u308b\u30bf\u30f3\u30d1\u30af\u8cea\u3067\u3059\uff08\u56f3\uff12\uff09\u3002<\/p>\n<\/div>\n<\/div>\n\n\n\n<div class=\"wp-block-columns is-layout-flex wp-container-core-columns-is-layout-9d6595d7 wp-block-columns-is-layout-flex\">\n<div class=\"wp-block-column is-layout-flow wp-block-column-is-layout-flow\" style=\"flex-basis:50%\">\n<p class=\"mtb_0\">\u3000DTC\u306e\u79fb\u52d5\u306b\u3088\u308a\u3001\u751f\u6b96\u5de3\u306f\u521d\u3081\u8179\u5074\u306e\u4f53\u58c1\u7b4b\u306b\u6cbf\u3063\u3066\u524d\u5f8c\u65b9\u5411\u306b\u4f38\u9577\u3057\u307e\u3059\u3002DTC\u306f2\u56de\u306e\u65b9\u5411\u8ee2\u63db\u3092\u3057\u3066\u3001U\u5b57\u578b\u306e\u751f\u6b96\u5de3\u306e\u5f62\u6210\u3092\u6307\u63ee\u3057\u307e\u3059\u304c\u3001\u3053\u306e\u65b9\u5411\u8ee2\u63db\u306b\u306f\u7d30\u80de\u79fb\u52d5\u306e\u30ac\u30a4\u30c9\u3068\u547c\u3070\u308c\u308b\u3057\u304f\u307f\u304c\u50cd\u304d\u307e\u3059\u3002\u7dda\u866b\u306e\u8179\u5074\u795e\u7d4c\u675f\u304b\u3089\u306f\u30cd\u30c8\u30ea\u30f3\u3068\u547c\u3070\u308c\u308b\u30ac\u30a4\u30c9\u30bf\u30f3\u30d1\u30af\u8cea\u304c\u5206\u6ccc\u3055\u308c\u3001\u8179\u5074\u3067\u6fc3\u5ea6\u304c\u9ad8\u304f\u3001\u80cc\u5074\u306b\u3044\u304f\u307b\u3069\u4f4e\u304f\u306a\u308b\u6fc3\u5ea6\u52fe\u914d\u3092\u5f62\u6210\u3057\u3066\u3044\u307e\u3059\uff08\u56f3\uff13\uff09\u30023\u9f62\u5e7c\u866b\u671f\u306b\u9054\u3057\u305f\u6bb5\u968e\u3067\u3001DTC\u306f1\u56de\u76ee\u306e\u80cc\u5074\u3078\u306e\u65b9\u5411\u8ee2\u63db\u3092\u3057\u307e\u3059\u304c\u3001DTC\u306f\u65b9\u5411\u8ee2\u63db\u306e\u76f4\u524d\u306b\u7d30\u80de\u819c\u4e0a\u306b\u30cd\u30c8\u30ea\u30f3\u306e\u6fc3\u5ea6\u3092\u611f\u3058\u308b\u30a2\u30f3\u30c6\u30ca\u3067\u3042\u308b\u53d7\u5bb9\u4f53\u3092\u767a\u73fe\u3057\u307e\u3059\u3002DTC\u306f\u30cd\u30c8\u30ea\u30f3\u306e\u6fc3\u5ea6\u3092\u611f\u3058\u3066\u3001\u3088\u308a\u6fc3\u5ea6\u306e\u4f4e\u3044\u80cc\u5074\u306b\u65b9\u5411\u8ee2\u63db\u3057\u307e\u3059\u30022\u56de\u76ee\u306e\u65b9\u5411\u8ee2\u63db\u306b\u306f\u30a6\u30a4\u30f3\u30c8\u3068\u547c\u3070\u308c\u308b\u30ac\u30a4\u30c9\u30bf\u30f3\u30d1\u30af\u8cea\u304c\u50cd\u304d\u307e\u3059\u3002\u30cd\u30c8\u30ea\u30f3\u3084\u30a6\u30a4\u30f3\u30c8\u306a\u3069\u306e\u30ac\u30a4\u30c9\u30bf\u30f3\u30d1\u30af\u8cea\u306f\u54fa\u4e73\u985e\u306e\u5668\u5b98\u5f62\u6210\u3067\u3082\u50cd\u304f\u3053\u3068\u304c\u77e5\u3089\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n<\/div>\n\n\n\n<div class=\"wp-block-column sp_box_ord_01 is-layout-flow wp-block-column-is-layout-flow\" style=\"flex-basis:50%\"><div class=\"wp-block-image\">\n<figure class=\"aligncenter size-full\"><img decoding=\"async\" width=\"1063\" height=\"639\" src=\"https:\/\/plaza.umin.ac.jp\/wormjp\/wordpress\/wp-content\/uploads\/2025\/01\/2-5_03.png\" alt=\"\" class=\"wp-image-428\" style=\"object-fit:cover\" srcset=\"https:\/\/plaza.umin.ac.jp\/wormjp\/wordpress\/wp-content\/uploads\/2025\/01\/2-5_03.png 1063w, https:\/\/plaza.umin.ac.jp\/wormjp\/wordpress\/wp-content\/uploads\/2025\/01\/2-5_03-300x180.png 300w, https:\/\/plaza.umin.ac.jp\/wormjp\/wordpress\/wp-content\/uploads\/2025\/01\/2-5_03-1024x616.png 1024w, https:\/\/plaza.umin.ac.jp\/wormjp\/wordpress\/wp-content\/uploads\/2025\/01\/2-5_03-768x462.png 768w, https:\/\/plaza.umin.ac.jp\/wormjp\/wordpress\/wp-content\/uploads\/2025\/01\/2-5_03-670x403.png 670w\" sizes=\"(max-width: 1063px) 100vw, 1063px\" \/><\/figure>\n<\/div><\/div>\n<\/div>\n\n\n\n<p><strong>\u53c2\u8003\u8cc7\u6599<\/strong><br>E. Jane Albert Hubbard and David Greenstein (2000). The <em>Caenorhabditis elegans<\/em> Gonad: A Test Tube for Cell and Developmental Biology. Developmental Dynamics&nbsp; 218:2-22.<\/p>\n\n\n\n<p><strong>\u76e3\u4fee\u8005<\/strong><br>\u897f\u8107\u3000\u6e05\u4e8c\u3000<br>1956\u5e74\u5927\u962a\u751f\u307e\u308c\u3002\u7dda\u866b\u306e\u80da\u767a\u751f\u7814\u7a76\u306b\u3088\u308a\u5927\u962a\u5e02\u7acb\u5927\u5b66\u3088\u308a\u535a\u58eb\u5b66\u4f4d\u3092\u53d6\u5f97\u3002NEC\u57fa\u790e\u7814\u7a76\u6240\u3001\u7406\u5316\u5b66\u7814\u7a76\u6240\u3092\u7d4c\u3066\u3001\u73fe\u5728\u3001\u95a2\u897f\u5b66\u9662\u5927\u5b66\u6559\u6388\u3068\u3057\u3066\u300c\u7dda\u866b\u306e\u5668\u5b98\u5f62\u6210\u6a5f\u69cb\u300d\u3092\u7814\u7a76\u3057\u3066\u3044\u308b\u3002<\/p>\n\n\n\n<p><strong>\u7814\u7a76\u5ba4HP<\/strong><br><a href=\"https:\/\/sci-tech.ksc.kwansei.ac.jp\/~nishiwaki\/\" target=\"_blank\" rel=\"noreferrer noopener\">https:\/\/sci-tech.ksc.kwansei.ac.jp\/~nishiwaki\/<\/a><\/p>\n\n\n\n<p class=\"has-text-align-right has-small-font-size\">\u00a92026 \u866b\u306e\u96c6\u3044\uff08\u7dda\u866b\u7814\u7a76\u8005\u30b3\u30df\u30e5\u30cb\u30c6\u30a3\uff09\u300c5.\u3000\u5f62\u614b\u5f62\u6210\u30fb\u5668\u5b98\u5f62\u6210\u300d<a href=\"https:\/\/creativecommons.org\/licenses\/by\/4.0\/\">CC BY<\/a><\/p>\n\n\n\n<p class=\"has-text-align-right\"><a href=\"#toc_container\" data-type=\"internal\" data-id=\"#toc_container\">\u76ee\u6b21\u30da\u30fc\u30b8\u3078\u2191<\/a><\/p>\n\n\n\n<div style=\"height:20px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n<\/div><\/section>\n\n\n\n<section id=\"section-6\" class=\"wp-block-group\"><div class=\"wp-block-group__inner-container is-layout-constrained wp-block-group-is-layout-constrained\">\n<h3 class=\"wp-block-heading\">6.\u3000\u30d7\u30ed\u30b0\u30e9\u30e0\u7d30\u80de\u6b7b\uff08\u30a2\u30dd\u30c8\u30fc\u30b7\u30b9\uff09<\/h3>\n\n\n\n<p>\u3000\u30d7\u30ed\u30b0\u30e9\u30e0\u7d30\u80de\u6b7b\uff08\u30a2\u30dd\u30c8\u30fc\u30b7\u30b9\uff09\u306f\u3001\u3042\u3089\u304b\u3058\u3081\u6c7a\u3081\u3089\u308c\u305f\u30d7\u30ed\u30b0\u30e9\u30e0\u306b\u3057\u305f\u304c\u3063\u3066\u7d30\u80de\u304c\u6b7b\u306c\u73fe\u8c61\u306e\u3053\u3068\u3067\u3059\u3002\u3053\u308c\u306f\u751f\u7269\u304c\u6b63\u5e38\u306b\u767a\u751f\u3057\u3001\u304b\u3089\u3060\u306e\u6a5f\u80fd\u3092\u7dad\u6301\u3059\u308b\u3046\u3048\u3067\u91cd\u8981\u306a\u3057\u304f\u307f\u306e\u4e00\u3064\u3067\u3059\u3002\u7dda\u866b<em>C. elegans<\/em>\u306e\u7d30\u80de\u7cfb\u8b5c\u306b\u306f\u500b\u4f53\u5dee\u304c\u306a\u304f\u3001\u96cc\u96c4\u540c\u4f53\u306e\u767a\u751f\u904e\u7a0b\u3067\u306f1090\u500b\u306e\u7d30\u80de\u304c\u4f5c\u3089\u308c\u3001\u305d\u306e\u3046\u3061131\u500b\u306e\u7d30\u80de\u304c\u30d7\u30ed\u30b0\u30e9\u30e0\u7d30\u80de\u6b7b\u3092\u9042\u3052\u307e\u3059\u3002<br>\u3000\u7d30\u80de\u6b7b\u304c\u8d77\u3053\u3089\u306a\u304f\u306a\u3063\u305f\u308a\u3001\u9006\u306b\u7d30\u80de\u6b7b\u304c\u904e\u5270\u306b\u8d77\u304d\u308b\u3088\u3046\u306b\u306a\u3063\u305f\u5909\u7570\u4f53\u306e\u907a\u4f1d\u5b66\u7684\u89e3\u6790\u306b\u3088\u3063\u3066\u3001\u30d7\u30ed\u30b0\u30e9\u30e0\u7d30\u80de\u6b7b\u306b\u95a2\u4e0e\u3059\u308b\u907a\u4f1d\u5b50\u7fa4\u304c\u7279\u5b9a\u3055\u308c\u3001\u305d\u306e\u907a\u4f1d\u5b50\u7d4c\u8def\u304c\u660e\u3089\u304b\u306b\u306a\u308a\u307e\u3057\u305f\u3002\u3055\u3089\u306b\u3001\u3053\u306e\u907a\u4f1d\u5b50\u7d4c\u8def\u306f\u3001\u7dda\u866b\u304b\u3089\u30d2\u30c8\u306b\u81f3\u308b\u307e\u3067\u591a\u69d8\u306a\u751f\u7269\u306b\u304a\u3044\u3066\u4fdd\u5b58\u3055\u308c\u3066\u3044\u308b\u3053\u3068\u304c\u308f\u304b\u3063\u3066\u3044\u307e\u3059\u3002<br>\u3000\u7d30\u80de\u6b7b\u306f\u3001\u6b7b\u306c\u7d30\u80de\u304c\u6c7a\u3081\u3089\u308c\u308b\u300c\u6307\u5b9a\u6bb5\u968e\u300d\u3001\u7d30\u80de\u6b7b\u306e\u30d7\u30ed\u30b0\u30e9\u30e0\u304c\u4f5c\u52d5\u3059\u308b\u300c\u6bba\u5bb3\u6bb5\u968e\u300d\u3001\u7d30\u80de\u304c\u5206\u89e3\u3055\u308c\u3001\u8fd1\u96a3\u306e\u7d30\u80de\u306b\u53d6\u308a\u8fbc\u307e\u308c\u308b\u300c\u5b9f\u884c\u6bb5\u968e\u300d\u3001\u306e\uff13\u3064\u306e\u30b9\u30c6\u30c3\u30d7\u3067\u884c\u308f\u308c\u307e\u3059\u3002<br>\u300c\u6bba\u5bb3\u6bb5\u968e\u300d\u306f\u3001EGL-1, CED-9, CED-4\u304c\u95a2\u4e0e\u3059\u308b\u4e00\u9023\u306e\u30bf\u30f3\u30d1\u30af\u76f8\u4e92\u4f5c\u7528\u306b\u3088\u3063\u3066\u7d30\u80de\u6b7b\u30d7\u30ed\u30c6\u30a2\u30fc\u30bcCED-3\u304c\u6d3b\u6027\u5316\u3055\u308c\u308b\u3068\u59cb\u307e\u308a\u307e\u3059\u3002<br>\u3000<em>C. elegans<\/em>\u306e\u7d30\u80de\u7cfb\u8b5c\u306e\u6c7a\u5b9a\u3068\u30d7\u30ed\u30b0\u30e9\u30e0\u7d30\u80de\u6b7b\u306e\u907a\u4f1d\u7684\u7d4c\u8def\u306e\u89e3\u660e\u3067\u4e3b\u5c0e\u7684\u306a\u5f79\u5272\u3092\u679c\u305f\u3057\u305f\u30b7\u30c9\u30cb\u30fc\u30fb\u30d6\u30ec\u30ca\u30fc\u3001\u30b8\u30e7\u30f3\u30fb\u30b5\u30eb\u30b9\u30c8\u30f3\u3001H.\u30ed\u30d0\u30fc\u30c8\u30fb\u30db\u30ed\u30f4\u30a3\u30c3\u30c4\u306b\u306f2002\u5e74\u306e\u30ce\u30fc\u30d9\u30eb\u751f\u7406\u5b66\u30fb\u533b\u5b66\u8cde\u304c\u6388\u4e0e\u3055\u308c\u307e\u3057\u305f\u3002<\/p>\n\n\n\n<p><strong>\u53c2\u8003\u8cc7\u6599<\/strong><br>1) Conradt B, Xue D. Programmed cell death, WormBook. 2005 Oct 6:1-13. doi: 10.1895\/wormbook.1.32.1.<br>2) Metzstein M, Stanfield GM, Horvitz HR. Genetics of programmed cell death in <em>C elegans<\/em>: past, present and future<\/p>\n\n\n\n<p><strong>\u76e3\u4fee\u8005<\/strong><br>\u6749\u672c\u3000\u4e9c\u7802\u5b50<br>\u6771\u4eac\u90fd\u751f\u307e\u308c\u3002\u6771\u4eac\u5927\u5b66\u5927\u5b66\u9662\u7406\u5b66\u7cfb\u7814\u7a76\u79d1\u535a\u58eb\u8ab2\u7a0b\u4fee\u4e86\u3002\u73fe\u5728\u3001\u6771\u5317\u5927\u5b66 \u7406\u4e8b\u30fb\u526f\u5b66\u9577\uff08\u7814\u7a76\u62c5\u5f53\uff09\u3001\u5927\u5b66\u9662\u751f\u547d\u79d1\u5b66\u7814\u7a76\u79d1\u30fb\u6559\u6388\u3002\u65e5\u672c\u5206\u5b50\u751f\u7269\u5b66\u4f1a\u7406\u4e8b\u9577\u3001WormBoard\uff08\u56fd\u969b\u7dda\u866b\u4f1a\u8b70\uff09\u521d\u4ee3\u30a2\u30b8\u30a2\u4ee3\u8868\u3082\u52d9\u3081\u305f\u3002<\/p>\n\n\n\n<p><strong>\u7814\u7a76\u5ba4HP<\/strong><br><a href=\"https:\/\/devdyn.wixsite.com\/sugimoto-lab\" target=\"_blank\" rel=\"noreferrer noopener\">https:\/\/devdyn.wixsite.com\/sugimoto-lab<\/a><\/p>\n\n\n\n<p class=\"has-text-align-right has-small-font-size\">\u00a92026 \u866b\u306e\u96c6\u3044\uff08\u7dda\u866b\u7814\u7a76\u8005\u30b3\u30df\u30e5\u30cb\u30c6\u30a3\uff09\u300c6.\u3000\u30d7\u30ed\u30b0\u30e9\u30e0\u7d30\u80de\u6b7b\uff08\u30a2\u30dd\u30c8\u30fc\u30b7\u30b9\uff09\u300d<a href=\"https:\/\/creativecommons.org\/licenses\/by\/4.0\/\">CC BY<\/a><\/p>\n\n\n\n<p class=\"has-text-align-right\"><a href=\"#toc_container\" data-type=\"internal\" data-id=\"#toc_container\">\u76ee\u6b21\u30da\u30fc\u30b8\u3078\u2191<\/a><\/p>\n<\/div><\/section>\n\n\n\n<p><\/p>\n","protected":false},"excerpt":{"rendered":"<p>\u76ee\u6b21 Illustrated by Hiroko Uchida&nbsp; \u79c1\u305f\u3061\u30d2\u30c8\u3068\u540c\u3058\u3088\u3046\u306b\u3001 [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":0,"parent":666,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"footnotes":""},"class_list":["post-674","page","type-page","status-publish","hentry"],"_links":{"self":[{"href":"https:\/\/plaza.umin.ac.jp\/wormjp\/wordpress\/wp-json\/wp\/v2\/pages\/674","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/plaza.umin.ac.jp\/wormjp\/wordpress\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/plaza.umin.ac.jp\/wormjp\/wordpress\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/plaza.umin.ac.jp\/wormjp\/wordpress\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/plaza.umin.ac.jp\/wormjp\/wordpress\/wp-json\/wp\/v2\/comments?post=674"}],"version-history":[{"count":13,"href":"https:\/\/plaza.umin.ac.jp\/wormjp\/wordpress\/wp-json\/wp\/v2\/pages\/674\/revisions"}],"predecessor-version":[{"id":1300,"href":"https:\/\/plaza.umin.ac.jp\/wormjp\/wordpress\/wp-json\/wp\/v2\/pages\/674\/revisions\/1300"}],"up":[{"embeddable":true,"href":"https:\/\/plaza.umin.ac.jp\/wormjp\/wordpress\/wp-json\/wp\/v2\/pages\/666"}],"wp:attachment":[{"href":"https:\/\/plaza.umin.ac.jp\/wormjp\/wordpress\/wp-json\/wp\/v2\/media?parent=674"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}