{"id":357,"date":"2020-10-09T14:46:46","date_gmt":"2020-10-09T05:46:46","guid":{"rendered":"https:\/\/plaza.umin.ac.jp\/tks\/?page_id=357"},"modified":"2020-10-13T11:06:33","modified_gmt":"2020-10-13T02:06:33","slug":"en","status":"publish","type":"page","link":"https:\/\/plaza.umin.ac.jp\/tks\/en\/","title":{"rendered":"Home"},"content":{"rendered":"<script>\n  var target = document.getElementById(\"site_name\")\n  target.href = \"https:\/\/plaza.umin.ac.jp\/tks\/en\"\n<\/script>\n<p>Takenouchi-Kosaki syndrome, a human disease caused by genetic changes in CDC42, is a congenital malformation syndrome characterized by macrothrombocytopenia, intellectual disability, characteristic facial features, sensorineural hearing loss, contracture of the fingers, lymphedema, repetitive infections, and hypothyroidism.<\/p>\n<div class=\"one_fourth\"><a href=\"https:\/\/plaza.umin.ac.jp\/tks\/en\/disease\/\"><\/p>\n<div class=\"home_box\">Disease overview<\/p>\n<p><i class=\"fas fa-3x fa-user-md\"><\/i>\n<\/div>\n<p><\/a><br \/><\/div>\n<div class=\"one_fourth\"><a href=\"https:\/\/plaza.umin.ac.jp\/tks\/en\/research\/\"><\/p>\n<div class=\"home_box\">Research summary<\/p>\n<p><i class=\"fas fa-3x fa-dna\"><\/i>\n<\/div>\n<p><\/a><br \/><\/div>\n<div class=\"one_fourth\"><p><a href=\"https:\/\/plaza.umin.ac.jp\/tks\/en\/criteria\/\"><\/p>\n<div class=\"home_box\">Diagnostic criteria<\/p>\n<p><i class=\"fas fa-3x fa-atlas\"><\/i>\n<\/div>\n<p><\/a><br \/><\/div>\n<div class=\"one_fourth last\"><a href=\"https:\/\/plaza.umin.ac.jp\/tks\/en\/members\/\"><\/p>\n<div class=\"home_box\">Members<\/p>\n<p><i class=\"fas fa-3x fa-users\"><\/i>\n<\/div>\n<p><\/a><\/p><\/div><div class=\"clearboth\"><\/div>\n<div class=\"two_third\"><h3>Information<\/h3>\n<ul>\n<li>2019-07-01<br \/><a href=\"https:\/\/www.shouman.jp\/disease\/details_next\/13_01_034\/\" rel=\"noopener noreferrer\" target=\"_blank\">Takenouchi-Kosaki syndrome has been added to Specific Pediatric Chronic Diseases.<\/a><\/li>\n<li>2018-12-10<br \/><a href=\"#\">The website of This research group has been launched.<\/a><\/li>\n<\/ul><\/div>\n<div class=\"one_third last\"><h3>Related Sites<\/h3>\n<p><a href=\"https:\/\/www.nanbyo-research.jp\/research\/1\/well-studied-gene-implicated-in-rare-syndrome\" class=\"dummy_banner\" target=\"_blank\" rel=\"noopener noreferrer\">NANBYO Research from Japan<\/a><br \/>\n<a href=\"https:\/\/www.shouman.jp\/\" class=\"dummy_banner\" target=\"_blank\" rel=\"noopener noreferrer\">Information Center for<br \/>Specific Pediatric Chronic Diseases<\/a><\/p><\/div><div class=\"clearboth\"><\/div>\n<div class=\"one_half\"><\/div>\n<div class=\"one_half last\"><\/div><div class=\"clearboth\"><\/div>\n","protected":false},"excerpt":{"rendered":"<p>Takenouchi-Kosaki syndrome, a human disease caused by genetic changes in CDC42, is a congenital malformation s &#8230;<\/p>\n","protected":false},"author":1,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":[],"_links":{"self":[{"href":"https:\/\/plaza.umin.ac.jp\/tks\/wp-json\/wp\/v2\/pages\/357"}],"collection":[{"href":"https:\/\/plaza.umin.ac.jp\/tks\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/plaza.umin.ac.jp\/tks\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/plaza.umin.ac.jp\/tks\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/plaza.umin.ac.jp\/tks\/wp-json\/wp\/v2\/comments?post=357"}],"version-history":[{"count":26,"href":"https:\/\/plaza.umin.ac.jp\/tks\/wp-json\/wp\/v2\/pages\/357\/revisions"}],"predecessor-version":[{"id":426,"href":"https:\/\/plaza.umin.ac.jp\/tks\/wp-json\/wp\/v2\/pages\/357\/revisions\/426"}],"wp:attachment":[{"href":"https:\/\/plaza.umin.ac.jp\/tks\/wp-json\/wp\/v2\/media?parent=357"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}