{"id":322,"date":"2020-10-05T15:37:14","date_gmt":"2020-10-05T06:37:14","guid":{"rendered":"https:\/\/plaza.umin.ac.jp\/tks\/?page_id=322"},"modified":"2020-10-12T16:35:08","modified_gmt":"2020-10-12T07:35:08","slug":"criteria","status":"publish","type":"page","link":"https:\/\/plaza.umin.ac.jp\/tks\/en\/criteria\/","title":{"rendered":"Diagnostic criteria"},"content":{"rendered":"<script>\n  var target = document.getElementById(\"site_name\")\n  target.href = \"https:\/\/plaza.umin.ac.jp\/tks\/en\"\n<\/script>\n<h2>Diagnostic criteria<br \/>\n <span style=\"font-size:75%; font-weight:normal\"> (according to the Japanese Society of Pediatric Genetics and the Japanese Society of Congenital Anomalies)<\/span><\/h2>\n<table style=\"width:100%;border-collapse: separate;\">\n<tbody>\n<tr>\n<td style=\"width:60%\">\n<h3>A\u3000Major symptoms<\/h3>\n<div class=\"one_third\"><\/div>\n<div class=\"two_third last\"><ol>\n<li>Macrothrombocytopenia<\/li>\n<li>Intellectual disability<\/li>\n<li>Sensorineural deafness<\/li>\n<li>Camptodactyly<\/li>\n<li>Structural brain abnormality<\/li>\n<\/ol><\/div><div class=\"clearboth\"><\/div>\n<h3>B\u3000Minor symptoms<\/h3>\n<div class=\"one_third\"><\/div>\n<div class=\"two_third last\"><ol>\nRecurrent infection<br \/>\nHypothyroidism<br \/>\nLymphedema\n<\/ol><\/div><div class=\"clearboth\"><\/div>\n<h3>C Genetic testing<\/h3>\n<div class=\"one_third\"><\/div>\n<div class=\"two_third last\"><ol>\n<li>Mutations in the CDC42 gene<\/li>\n<\/ol><\/div><div class=\"clearboth\"><\/div>\n<\/td>\n<td style=\"width:3%;border:2px solid #999; border-radius:0 20px 20px 0; border-left:none; text-align:right;\">\n<div class=\"triangle\"><\/div>\n<\/td>\n<td style=\"width:35%; padding-left:20px;\">\n<p><strong>&laquo;Diagnostic Category&raquo;<\/strong><\/p>\n<dl>\n<dt>Definite\uff1a<\/dt\n\n<dd>\u3000Four or more of the items in A plus C<\/dd>\n<dt>Probable\uff1a<\/dt\n\n<dd>\u3000Three items in A plus one or more of B<\/dd>\n<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n","protected":false},"excerpt":{"rendered":"<p>Diagnostic criteria (according to the Japanese Society of Pediatric Genetics and the Japanese Society of Conge &#8230;<\/p>\n","protected":false},"author":1,"featured_media":0,"parent":357,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":[],"_links":{"self":[{"href":"https:\/\/plaza.umin.ac.jp\/tks\/wp-json\/wp\/v2\/pages\/322"}],"collection":[{"href":"https:\/\/plaza.umin.ac.jp\/tks\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/plaza.umin.ac.jp\/tks\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/plaza.umin.ac.jp\/tks\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/plaza.umin.ac.jp\/tks\/wp-json\/wp\/v2\/comments?post=322"}],"version-history":[{"count":2,"href":"https:\/\/plaza.umin.ac.jp\/tks\/wp-json\/wp\/v2\/pages\/322\/revisions"}],"predecessor-version":[{"id":404,"href":"https:\/\/plaza.umin.ac.jp\/tks\/wp-json\/wp\/v2\/pages\/322\/revisions\/404"}],"up":[{"embeddable":true,"href":"https:\/\/plaza.umin.ac.jp\/tks\/wp-json\/wp\/v2\/pages\/357"}],"wp:attachment":[{"href":"https:\/\/plaza.umin.ac.jp\/tks\/wp-json\/wp\/v2\/media?parent=322"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}