{"id":8197,"date":"2015-11-15T09:17:40","date_gmt":"2015-11-15T00:17:40","guid":{"rendered":"\/sawamura\/?p=8197"},"modified":"2025-02-05T16:11:11","modified_gmt":"2025-02-05T07:11:11","slug":"particleprotonbeam","status":"publish","type":"post","link":"https:\/\/plaza.umin.ac.jp\/sawamura\/braintumors\/particleprotonbeam\/","title":{"rendered":"\u7c92\u5b50\u7dda\u6cbb\u7642\uff0c\u967d\u5b50\u7dda\u6cbb\u7642 proton radiotherapy"},"content":{"rendered":"<h5>\u5927\u5207\u306a\u3053\u3068<\/h5>\n<ul>\n<li>\u967d\u5b50\u7dda\u6cbb\u7642\u3068\u91cd\u7c92\u5b50\u7dda\u6cbb\u7642\u3068\u4e2d\u6027\u5b50\u7dda\u6cbb\u7642\u3092\u4f75\u305b\u3066\u7c92\u5b50\u7dda\u6cbb\u7642\u3068\u8a00\u3044\u307e\u3059<\/li>\n<li><strong><span style=\"color: #ff0000;\">\u967d\u5b50\u7dda\u6cbb\u7642<\/span><\/strong>\u306f\u6c34\u7d20\u306e\u539f\u5b50\u6838\uff08\u967d\u5b50\uff09\u3092\u52a0\u901f\u3057\u3066\u60a3\u90e8\u306b\u5f53\u3066\u308b\u65b9\u6cd5\u3067\u3059<\/li>\n<li><strong><span style=\"color: #ff0000;\">\u91cd\u7c92\u5b50\u7dda\u6cbb\u7642<\/span><\/strong>\u3068\u306f\u70ad\u7d20\u30a4\u30aa\u30f3\u3092\u52a0\u901f\u3057\u3066\u60a3\u90e8\u306b\u5f53\u3066\u308b\u65b9\u6cd5\u3067\u3059<\/li>\n<li><span style=\"color: #000000;\">\u7c92\u5b50\u7dda\u6cbb\u7642\u306e\u7279\u5fb4\u306f\uff0c<span style=\"color: #000080;\"><strong>\u4f53\u306e\u6df1\u3044\u3068\u3053\u308d\u306b\u3042\u308b\u816b\u760d\u306b\u96c6\u4e2d\u7684\u306b\u3088\u308a\u591a\u304f\u306e\u653e\u5c04\u7dda\u91cf<\/strong><\/span>\u304c\u304b\u3051\u3089\u308c\u308b\u306e\u3067\u6d45\u3044\u3068\u3053\u308d\u306e\u6b63\u5e38\u306a\u7d44\u7e54\u306e\u640d\u50b7\u3092\u4f4e\u304f\u6291\u3048\u3089\u308c\u308b\u3053\u3068\u3067\u3059<\/span><\/li>\n<li>\u901a\u5e38\u306e\u653e\u5c04\u7dda\u6cbb\u7642\uff08X\u7dda\u3068\u03b3\u7dda\uff09\u3067\u306f\u30a8\u30cd\u30eb\u30ae\u30fc\u306f\u8868\u9762\u304b\u3089\u6e1b\u8870\u3057\u3066\u3044\u304d\u307e\u3059\u304c\uff0c\u7c92\u5b50\u7dda\u3067\u306f\u7dda\u91cf\u306e\u30d4\u30fc\u30af\u309210cm\u4ee5\u4e0a\u306e\u6df1\u3044\u3068\u3053\u308d\u3078\u6301\u3063\u3066\u3044\u3051\u308b\u304b\u3089\u3067\u3059<\/li>\n<li>\u6cbb\u7642\u3067\u304d\u308b\u4ee3\u8868\u7684\u306a\u304c\u3093\u306f\u524d\u7acb\u817a\u304c\u3093\u3067\uff0c\u982d\u84cb\u5e95\u60aa\u6027\u816b\u760d\u3092\u542b\u3080\u982d\u981a\u90e8\u764c\u306b\u3082\u3042\u308b\u7a0b\u5ea6\u306e\u6210\u7e3e\u304c\u898b\u8fbc\u3081\u307e\u3059<\/li>\n<li><strong><span style=\"color: #000080;\">\u4e2d\u6027\u5b50\u6355\u6349\u7642\u6cd5 BNCT<\/span><\/strong>\u3068\u3044\u3046\u306e\u306f\u534a\u4e16\u7d00\u8fd1\u304f\u8133\u816b\u760d\u306b\u4f7f\u308f\u308c\u3066\u3044\u307e\u3059\u304c\u52b9\u679c\u306f\u307f\u3048\u307e\u305b\u3093<\/li>\n<li><strong><span style=\"color: #ff0000;\">\u6b8b\u5ff5\u306a\u304c\u3089\u901a\u5e38\u306e\u8133\u816b\u760d\u3067\u306f\u7c92\u5b50\u7dda\uff08\u967d\u5b50\u7dda\uff09\u306e\u5229\u70b9\u306f\u306f\u3063\u304d\u308a\u3057\u307e\u305b\u3093<\/span><\/strong><\/li>\n<li>\u967d\u5b50\u7dda\u3060\u3068\u6cbb\u308b\u78ba\u7387\u304c\u9ad8\u304f\u306a\u308b\u3068\u3044\u3046\u8133\u816b\u760d\u306f\u77e5\u3089\u308c\u3066\u3044\u307e\u305b\u3093<\/li>\n<li>\u967d\u5b50\u7dda\u3067\u8133\u3084\u795e\u7d4c\u306e\u640d\u50b7\u304c\u5c11\u306a\u304f\u306a\u3063\u305f\u3068\u3044\u3046\u660e\u77ad\u306a\u79d1\u5b66\u7684\u8a3c\u62e0\u306f\u3042\u308a\u307e\u305b\u3093<\/li>\n<li><span style=\"color: #000080;\"><strong>2019\u5e74\uff0c\u5c0f\u5150\u9ac4\u82bd\u816b\u4f4e\u30ea\u30b9\u30af\u7fa4\u306b\u8133\u810a\u9ac4\u7167\u5c04 (23.4\u30b0\u30ec\u30a4) \u3068\u816b\u760d\u5c40\u6240\u7167\u5c04\u3092\u7528\u3044\u305f\u5834\u5408\uff0c\u967d\u5b50\u7dda\u306e\u65b9\u304c\u77e5\u80fd\u4e88\u5f8c\u304c\u826f\u3044\u3068\u306e\u5831\u544a\u304c\u306a\u3055\u308c\u307e\u3057\u305f\uff0c\u5c0f\u8133\u5c40\u6240\u7167\u5c04\u6642\u306e\u5927\u8133\u88ab\u66dd\u304c\u967d\u5b50\u7dda\u3067\u306f\u4f4e\u4e0b\u3057\u305f\u3068\u63a8\u5b9a\u3055\u308c\u307e\u3059<\/strong><\/span><\/li>\n<li>\u3053\u308c\u3088\u308a\u9ad8\u3044\u7dda\u91cf\u3067\u306f\u305d\u306e\u9055\u3044\u306f\u306f\u3063\u304d\u308a\u3057\u3066\u3044\u307e\u305b\u3093<\/li>\n<li><span style=\"color: #000080;\"><strong>\u967d\u5b50\u7dda\u3067\u3082\u8a8d\u77e5\u6a5f\u80fd\u306e\u4f4e\u4e0b\u306f\u751f\u3058\u307e\u3059<\/strong><\/span>\uff0c\u3067\u3082\u5f93\u6765\u306e\u5149\u5b50\u7dda photon\uff08\u653e\u5c04\u7dda\u6cbb\u7642\uff09\u3068\u9577\u671f\u4e88\u5f8c\u3092\u6bd4\u8f03\u3059\u308b\u30c7\u30fc\u30bf\u306f\u660e\u3089\u304b\u306b\u306a\u3063\u3066\u3044\u307e\u305b\u3093<\/li>\n<li>\u4f53\u306e\u4e2d\u3067\u3082\u8133\u306f\u7c92\u5b50\u7dda\u306b\u3088\u308b\u969c\u5bb3\u3092\u53d7\u3051\u3084\u3059\u3044\u5834\u6240\u3060\u3068\u8003\u3048\u3089\u308c\u307e\u3059<\/li>\n<li><span style=\"color: #000080;\"><strong>2016\u5e744\u6708\u304b\u3089\u5c0f\u5150\u8133\u816b\u760d\uff08\u9650\u5c40\u6027\u306e\u56fa\u5f62\u60aa\u6027\u816b\u760d\uff09\u306b\u967d\u5b50\u7dda\u306e\u4fdd\u967a\u8a3a\u7642<\/strong><\/span>\u304c\u8a8d\u3081\u3089\u308c\u307e\u3057\u305f<\/li>\n<li>\u5c0f\u5150\u4ee5\u5916\u306f\u4fdd\u967a\u8a3a\u7642\u304c\u8a8d\u3081\u3089\u308c\u3066\u3044\u306a\u3044\u306e\u3067\uff0c<span style=\"color: #000080;\"><strong>\u967d\u5b50\u7dda\u3067250\u4e07\u5186\uff0c\u91cd\u7c92\u5b50\u7dda\u3067<\/strong><strong>300\u4e07\u5186\u304f\u3089\u3044\u306e\u81ea\u5df1\u8ca0\u62c5<\/strong><\/span>\u306b\u306a\u308a\u307e\u3059<\/li>\n<li>\u65e5\u672c\u3067\u306f2020\u5e74\u3067\uff0c18\u30ab\u6240\u306e\u967d\u5b50\u7dda\u6cbb\u7642\u65bd\u8a2d\u304c\u3042\u308a\u307e\u3059<\/li>\n<li>\u5b9f\u969b\u306b\uff0c<strong><span style=\"color: #000080;\">\u5c0f\u5150\u8133\u816b\u760d\u306b\u5bfe\u3057\u3066\u4f7f\u7528<\/span><\/strong>\u3055\u308c\u308b\u3053\u3068\u304c\u591a\u304f\u306a\u3063\u3066\u3044\u307e\u3059<\/li>\n<\/ul>\n<h1>\u967d\u5b50\u7dda\u6cbb\u7642 proton beam<\/h1>\n<h5><strong>\u967d\u5b50\u7dda\u6cbb\u7642\u306e\u5229\u70b9<\/strong><\/h5>\n<ul>\n<li>\u967d\u5b50\u7dda\u306f\u6df1\u90e8\u306b\u30d4\u30fc\u30af\u3092\u4f5c\u308b\u3053\u3068\u3067\u304d\u308b\u306e\u3067\uff0c\u6df1\u3044\u4f4d\u7f6e\u306b\u3042\u308b\u8133\u816b\u760d\u306b\u304b\u3051\u308b\u3068\uff0c\u967d\u5b50\u7dda\u306e\u901a\u308a\u9053\u306b\u306a\u3063\u305f\u6b63\u5e38\u8133\u306e\u88ab\u66dd\u3092\u5c11\u306a\u304f\u3059\u308b\u3053\u3068\u304c\u3067\u304d\u307e\u3059<\/li>\n<li>\u7279\u306b\u5927\u304d\u306a\u75c5\u5de3\u306b\u5bfe\u3057\u3066\u3001\u6b63\u5e38\u7d44\u7e54\u306b\u304b\u304b\u308b\u7dda\u91cf\u3092\u6e1b\u3089\u3057\u3066\u816b\u760d\u306b\u304b\u304b\u308b\u7dda\u91cf\u3092\u5747\u4e00\u306b\u3059\u308b\u7279\u5fb4\u3092\u3082\u3063\u3066\u3044\u307e\u3059 (<strong><span style=\"color: #000080;\">IMRT<\/span><\/strong>\u306a\u3069\u3092\u5fdc\u7528\u3057\u307e\u3059\uff0c\u967d\u5b50\u7dda\u6cbb\u7642\u3067\u306f<span style=\"color: #000080;\"><strong>IMPT<\/strong><\/span>\u3068\u3044\u3044\u307e\u3059\uff09<\/li>\n<li>\u3067\u3059\u304b\u3089\u3001\u624b\u8853\u304c\u3067\u304d\u306a\u3044\u3088\u3046\u306b\u5e83\u304c\u3063\u305f\u60aa\u6027\u9ac4\u819c\u816b\u306e\u518d\u767a\u306a\u3069\u3001\u5927\u304d\u306a\u304b\u3064\u901a\u5e38\u306e\u653e\u5c04\u7dda\u6cbb\u7642\u306b\u62b5\u6297\u6027\u306e\u816b\u760d\u306b\u5341\u5206\u306a\u7dda\u91cf\u304c\u304b\u3051\u3089\u308c\u307e\u3059<\/li>\n<li>\u540c\u3058\u3088\u3046\u306b\u982d\u84cb\u5e95\u60aa\u6027\u816b\u760d\u3084\u810a\u7d22\u816b\u3067\u3082\u5927\u7dda\u91cf\u3092\u304b\u3051\u308b\u3053\u3068\u304c\u3067\u304d\u307e\u3059<\/li>\n<li>\u8907\u96d1\u306a\u5f62\u306e\u8133\u816b\u760d\u306b\u5bfe\u3057\u3066\u653e\u5c04\u7dda\u3092\u8907\u96d1\u306a\u5f62\u3067\u304b\u3051\u308b\u3053\u3068\u304c\u3067\u304d\u307e\u3059<\/li>\n<li>\u3064\u307e\u308a\uff0c<span style=\"color: #000080;\"><strong>\u30ac\u30f3\u30de\u7dda IMRT\u3088\u308a\u6cbb\u7642\u8a08\u753b\u304c\u3057\u3084\u3059\u304f\u4f4e\u7dda\u91cf\u88ab\u7206\u9818\u57df\u304c\u5c11\u306a\u3044<\/strong><\/span><span style=\"color: #000000;\">\u3068\u306e\u3053\u3068\u3067\u3059<\/span><\/li>\n<li><span style=\"color: #000080;\"><strong>\u901a\u5e38\u306e\u8133\u816b\u760d\u3078\u306e\u5bfe\u816b\u760d\u52b9\u679c\u3068\u3057\u3066\u306f\u30ac\u30f3\u30de\u7dda IMRT\u3068\u967d\u5b50\u7dda IMPT\u306e\u5dee\u306f\u3042\u307e\u308a\u3042\u308a\u307e\u305b\u3093<\/strong><\/span><\/li>\n<li>\u5f93\u3063\u3066\uff0c\u6210\u4eba\u8133\u816b\u760d\u306b\u5bfe\u3057\u3066\u306f\u982d\u84cb\u5e95\u816b\u760d\u4ee5\u5916\u306b\u306f\u4f7f\u7528\u3055\u308c\u3066\u3044\u306a\u3044\u306e\u304c\u73fe\u72b6\u3067\u3059<\/li>\n<li><span style=\"color: #000000;\">\u516c\u7684\u75c5\u9662\u3067\u306f\u306a\u3044\u65bd\u8a2d\u304b\u3089\u967d\u5b50\u7dda\u3092\u8a87\u5f35\u5ba3\u4f1d\u3059\u308b\u8a18\u4e8b\u3067\u306f\uff0c<\/span><strong><span style=\"color: #000080;\">\u300c\u304c\u3093\u75c5\u5de3\u524d\u5f8c\u306e\u6b63\u5e38\u7d44\u7e54\u3078\u306e\u30c0\u30e1\u30fc\u30b8\u306f\u307b\u3068\u3093\u3069\u306a\u304f\u3001\u4f53\u306b\u512a\u3057\u3044\u304c\u3093\u6cbb\u7642\u300d\u3068\u66f8\u3044\u3066\u3042\u308a\u307e\u3059\u304c\uff0c\u30a4\u30f3\u30c1\u30ad\u3060\u3068\u8a00\u3048\u307e\u3059<\/span><\/strong><\/li>\n<\/ul>\n<h5>\u967d\u5b50\u7dda\u304c\u9069\u5fdc\u3068\u306a\u308b\u8133\u816b\u760d\uff08\u982d\u9838\u90e8\u816b\u760d\uff09<\/h5>\n<ul>\n<li>\u810a\u7d22\u816b chordoma<\/li>\n<li>\u60aa\u6027\u9ac4\u819c\u816b malignant meningioma<\/li>\n<li>\u8edf\u9aa8\u8089\u816b chondrosarcoma<\/li>\n<li>\u5c0f\u5150\u8133\u816b\u760d\u306e\u4e00\u90e8<\/li>\n<\/ul>\n<h5>\u5c0f\u5150\u8133\u816b\u760d\u306b\u967d\u5b50\u7dda\u6cbb\u7642\u3092\u4f7f\u308f\u306a\u3044\u304b\uff1f\u4f7f\u3046\u306e\u304b\uff1f<\/h5>\n<ul>\n<li>\u304a\u533b\u8005\u3055\u3093\uff08\u5c0f\u5150\u79d1\u533b\u3068\u8133\u5916\u79d1\u533b\uff09\u306b\u306f\u967d\u5b50\u7dda\u306f\u6b63\u5e38\u306e\u8133\u304c\u88ab\u66dd\u3057\u306a\u3044\u304b\u3089\uff0c\u77e5\u80fd\u4f4e\u4e0b\u3092\u9632\u3052\u308b\u3068\u3044\u3046\u671f\u5f85\u3092\u3054\u4e21\u89aa\u306b\u904e\u5ea6\u306b\u3044\u3060\u304b\u305b\u308b\u50be\u5411\u304c\u3042\u308b\u306e\u3067\uff0c\u307e\u305a\u6ce8\u610f\u3067\u3059<\/li>\n<li>\u305d\u308c\u306f\u8a3c\u660e\u3055\u308c\u3066\u3044\u307e\u305b\u3093\u3057\uff0c\u304a\u305d\u3089\u304f\u6700\u65b0\u306e\u30ac\u30f3\u30de\u7dda photon \u7167\u5c04\u88c5\u7f6e\u3068\u7167\u5c04\u65b9\u3092\u4f7f\u3048\u3070\u967d\u5b50\u7dda\u3088\u308a\u6b63\u5e38\u8133\u7d44\u7e54\u304c\u5b88\u308c\u308b\u3068\u3044\u3046\u610f\u898b\u3082\u3042\u308a\u307e\u3059<\/li>\n<li>\u65b0\u3057\u3044\u6cbb\u7642\u6cd5\u304c\u3042\u308c\u3070\uff0c\u4e21\u89aa\u3082\u4e3b\u6cbb\u533b\u3082\uff0c\u85c1\u3092\u3082\u3059\u304c\u308b\u3068\u3044\u3046\u75c5\u6c17\u3067\u3059<\/li>\n<li>\u8a8d\u77e5\u6a5f\u80fd\u3092\u5b88\u308b\u305f\u3081\u306b\u306f\u3069\u3093\u306a\u53ef\u80fd\u6027\u3068\u3057\u3066\u306e\u624b\u6bb5\u3082\u5229\u7528\u3059\u308b\u3068\u3044\u3046\u8003\u3048\u3082\u3042\u308a\u307e\u3059<\/li>\n<li>\u5b9f\u969b\u306b\u306f\uff0c\u982d\u84cb\u54bd\u982d\u816b\u3084\u4e0a\u8863\u816b\u306a\u3069\u306b\u5e83\u304f\u7528\u3044\u3089\u308c\u3066\u3044\u307e\u3059<\/li>\n<li>\u6ce8\u610f\u3059\u308b\u3053\u3068\u306f\uff0c\u5f93\u6765\u306e\u653e\u5c04\u7dda\u6cbb\u7642\u3067\u6cbb\u308b\u306f\u305a\u306e\u816b\u760d\u306b\u967d\u5b50\u7dda\u3092\u4f7f\u7528\u3057\u3066\u751f\u547d\u4e88\u5f8c\u3092\u60aa\u5316\u3055\u305b\u3066\u3057\u307e\u3046\u3068\u3044\u3046\u3053\u3068\u3067\u3059<\/li>\n<li>\u3042\u304f\u307e\u3067\u3082\u9ad8\u5ea6\u306a\u77e5\u8b58\u3092\u3082\u3063\u305f\u5c02\u9580\u5bb6\u304c\u305d\u306e\u512a\u4f4d\u6027\u3092\u3057\u3063\u304b\u308a\u3068\u898b\u636e\u3048\u305f\u4e0a\u3067\u306e\u967d\u5b50\u7dda\u9078\u629e\u3068\u306a\u308a\u307e\u3059<\/li>\n<li>\u307e\u305f\u967d\u5b50\u7dda\u304c\u3042\u308b\u304b\u3089\u3068\u3044\u3063\u3066\u30ea\u30b9\u30af\u304c\u9ad8\u3044\u5916\u79d1\u624b\u8853\u3092\u4e2d\u9014\u534a\u7aef\u306a\u7d50\u679c\u306b\u7d42\u308f\u3089\u305b\u305f\u6642\uff0c\u967d\u5b50\u7dda\u306e\u4fb5\u8972\u5ea6\u304c\u9ad8\u304f\u306a\u308a\uff0c\u9577\u671f\u6210\u7e3e\u3092\u307f\u308c\u3070\u306a\u306b\u3092\u3057\u305f\u306e\u304b\u308f\u304b\u3089\u306a\u304f\u306a\u308b\u3053\u3068\u3082\u3042\u308a\u307e\u3059<\/li>\n<li>\u3068\u304f\u306b\uff0c\u982d\u84cb\u54bd\u982d\u816b\u3068\u4e0a\u8863\u816b\u3067\u306f\u3053\u306e\u70b9\u306b\u6ce8\u610f\u3059\u308b\u5fc5\u8981\u304c\u3042\u308a\u307e\u3059<\/li>\n<li>\u300c\u982d\u84cb\u54bd\u982d\u816b\u3068\u4e0a\u8863\u816b\u306f\u624b\u8853\u3067\u5b8c\u5168\u6458\u51fa\u3067\u304d\u305f\u3068\u304d\u306b\u9577\u671f\u4e88\u5f8c\u306b\u671f\u5f85\u304c\u62b1\u3051\u308b\u300d\u3068\u3044\u3046\u4e8b\u5b9f\u306f\uff0c\u967d\u5b50\u7dda\u6cbb\u7642\u304c\u767a\u9054\u3057\u3066\u3082\u5909\u308f\u308a\u304c\u306a\u3044\u3053\u3068\u3067\u3059<\/li>\n<\/ul>\n<h5>\u308f\u304b\u308a\u306b\u304f\u3044\u3051\u3069\u57fa\u672c\u7684\u306a\u3053\u3068<\/h5>\n<ul>\n<li><strong><span style=\"color: #000080;\">\u96fb\u78c1\u6ce2<\/span><\/strong>\uff08\u5149\u5b50\u7dda photon\uff09\uff1a\u3000X\u7dda\uff0c<span style=\"color: #ff0000;\"><strong>\u30ac\u30f3\u30de\u7dda<\/strong><\/span><\/li>\n<li><strong><span style=\"color: #000080;\">\u7c92\u5b50\u7dda<\/span><\/strong>\uff1a\u3000\u3000\u3000\u3000\u3000\u3000 \u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a0\u96fb\u5b50\u7dda\uff0c<span style=\"color: #ff0000;\"><strong>\u967d\u5b50\u7dda<\/strong><\/span>\uff0c\u4e2d\u6027\u5b50\u7dda\uff0c\u91cd\u7c92\u5b50\u7dda\uff08\u70ad\u7d20\u7dda\uff09<\/li>\n<\/ul>\n<p>\u653e\u5c04\u7dda\u306b\u306f\uff12\u7a2e\u985e\u3042\u308a\u307e\u3059\u304c\uff0c\u73fe\u5b9f\u7684\u306b\u8133\u816b\u760d\u306e\u6cbb\u7642\u3067\u4f7f\u7528\u3055\u308c\u308b\u306e\u306f\u30ac\u30f3\u30de\u7dda\u3068\u967d\u5b50\u7dda\u3060\u3051\u3067\u3059\u3002\u5f93\u6765\u306e\u653e\u5c04\u7dda\u6cbb\u7642\u306f\uff0c\u5149\u5b50\u7dda photon beam \uff08\u4e3b\u306b\u03b3\u7dda\uff09\u3092\u5229\u7528\u3057\u305f ionizing irradiaiton\u3067\u3059\u3002<span style=\"color: #000080;\"><strong>\u7c92\u5b50\u7dda particle beam\u00a0<\/strong><\/span>\u3068\u3044\u3046\u306e\u306f\uff0c\u6c34\u7d20\u306e\u539f\u5b50\u6838\uff08\u30d7\u30ed\u30c8\u30f3\uff0c\u967d\u5b50\u7dda\uff09\u3084\u70ad\u7d20\u306e\u539f\u5b50\u6838\uff08\u30ab\u30fc\u30dc\u30f3\uff0c\u70ad\u7d20\u7dda\uff09\u3092\u5229\u7528\u3057\u305f\u653e\u5c04\u7dda\u6cbb\u7642\u3067\u3059\u3002<\/p>\n<h5>\u30d6\u30e9\u30c3\u30b0\u30d4\u30fc\u30af Bragg peak<\/h5>\n<p><img loading=\"lazy\" decoding=\"async\" class=\"alignleft size-medium wp-image-8205\" src=\"\/sawamura\/wp\/wp-content\/uploads\/2015\/11\/braggpeak-300x202.png\" alt=\"braggpeak\" width=\"300\" height=\"202\" srcset=\"https:\/\/plaza.umin.ac.jp\/sawamura\/wp\/wp-content\/uploads\/2015\/11\/braggpeak-300x202.png 300w, https:\/\/plaza.umin.ac.jp\/sawamura\/wp\/wp-content\/uploads\/2015\/11\/braggpeak-550x370.png 550w, https:\/\/plaza.umin.ac.jp\/sawamura\/wp\/wp-content\/uploads\/2015\/11\/braggpeak.png 681w\" sizes=\"auto, (max-width: 300px) 100vw, 300px\" \/>Wikipedia\u304b\u3089\u306e\u5f15\u7528\u3067\u3059\u3002\u30d4\u30f3\u30af\u306e\u5149\u5b50\u7dda\uff08\u30ac\u30f3\u30de\u7dda\uff09\u306f\u8133\u306e\u8868\u9762\u304b\u3089\u6df1\u304f\u306a\u308b\u3068\u30a8\u30cd\u30eb\u30ae\u30fc\u304c\u6e1b\u8870\u3057\u3066\u3044\u304d\u307e\u3059\u3002\u3067\u3082\u9752\u306e\u967d\u5b50\u7dda\u3067\u306f\uff0c\u6df1\u305520cm\u304f\u3089\u3044\u306e\u3068\u3053\u308d\u3067\u30d4\u30fc\u30af\u304c\u3042\u308a\u30a8\u30cd\u30eb\u30ae\u30fc\u653e\u51fa\u304c\u6700\u5927\u3068\u306a\u308a\u307e\u3059\u3002\u6df1\u3044\u3068\u3053\u308d\u306e\u816b\u760d\u306b\u52b9\u7387\u7684\u306b\u88ab\u66dd\u3092\u5927\u304d\u304f\u3067\u304d\u307e\u3059\u3002<\/p>\n<p>\u554f\u984c\u306f\uff0c\u982d\u84cb\u306f\u524d\u5f8c\u5f84\u3067\u308218cm\u304f\u3089\u3044\u5e45\u306f15cm\u304f\u3089\u3044\u3068\u3044\u3046\u3053\u3068\u3067\u3059\u3002\u3053\u306e20cm\u306e\u30d6\u30e9\u30c3\u30b0\u30d4\u30fc\u30af\u3060\u3068\u982d\u3092\u8d85\u3048\u3066\u3057\u307e\u3044\u307e\u3059\u3002\u8133\u306e\u4e2d\u5fc3\u90e8\u306e\u816b\u760d\u3068\u3044\u3063\u3066\u3082\u8868\u9762\u304b\u3089\u305f\u304b\u3060\u304b10cm\u3067\u3057\u3087\u3046\u3002\u307e\u305f\u6d45\u3044\u3068\u3053\u308d\u306b\u88ab\u66dd\u304c\u5c11\u306a\u3044\u3068\u3044\u3063\u3066\u308250\uff05dose\u304f\u3089\u3044\u306f\u5165\u308a\u307e\u3059\u3002\u967d\u5b50\u7dda\u3092\u9032\u3081\u308b\u30cd\u30c3\u30c8\u4e0a\u306e\u60c5\u5831\u3067\u306f\uff0c\u6b63\u5e38\u8133\u306b\u5168\u304f\u653e\u5c04\u7dda\u304c\u5165\u3089\u306a\u3044\u3088\u3046\u306a\u8a18\u8ff0\u3092\u3057\u3066\u3044\u308b\u306e\u3067\u3059\u304c\uff0c\u3054\u307e\u304b\u3055\u308c\u306a\u3044\u3088\u3046\u306b\u3057\u307e\u3057\u3087\u3046\u3002<\/p>\n<h5>ballistics<\/h5>\n<p><img loading=\"lazy\" decoding=\"async\" class=\"alignleft size-large wp-image-8200\" src=\"\/sawamura\/wp\/wp-content\/uploads\/2015\/11\/ballistics-550x413.jpg\" alt=\"ballistics\" width=\"550\" height=\"413\" srcset=\"https:\/\/plaza.umin.ac.jp\/sawamura\/wp\/wp-content\/uploads\/2015\/11\/ballistics-550x413.jpg 550w, https:\/\/plaza.umin.ac.jp\/sawamura\/wp\/wp-content\/uploads\/2015\/11\/ballistics-300x225.jpg 300w, https:\/\/plaza.umin.ac.jp\/sawamura\/wp\/wp-content\/uploads\/2015\/11\/ballistics.jpg 850w\" sizes=\"auto, (max-width: 550px) 100vw, 550px\" \/><\/p>\n<p>\u653e\u5c04\u7dda\u306e\u8ecc\u9053\u5236\u5fa1\u3092ballistics\u3068\u3044\u3044\u307e\u3059\uff0c\u967d\u5b50\u7dda\u306f\u5f93\u6765\u306e\u30ac\u30f3\u30de\u7dda\u6cbb\u7642\u3088\u308a\u3082ballistics\u304c\u975e\u5e38\u306b\u826f\u3044\u3068\u3055\u308c\u307e\u3059\u3002\u9ad8\u5ea6\u306b\u5236\u5fa1\u3055\u308c\u305f\u30df\u30b5\u30a4\u30eb\u304c\u6a19\u7684\u3060\u3051\u3092\u78ba\u5b9f\u306b\u7834\u58ca\u3059\u308b\u306e\u3068\u540c\u3058\u3088\u3046\u306b\uff0c\u6b63\u5e38\u8133\u306e\u88ab\u66dd\u3092\u6291\u3048\u3066\u30bf\u30fc\u30b2\u30c3\u30c8\uff08\u8133\u816b\u760d\uff09\u3092\u7834\u58ca\u3059\u308b\u3068\u3044\u3046\u3088\u3046\u306a\u7406\u8ad6\u3067\u3059\u3002\u3067\u3082\u3042\u304f\u307e\u3067\u3082\u7406\u8ad6\u3067\u3059\u3002<\/p>\n<h5>\u91cd\u7c92\u5b50\u7dda\u6cbb\u7642\uff08\u70ad\u7d20\u7dda\uff09\u306e\u653e\u5c04\u7dda\u58ca\u6b7b<\/h5>\n<p><a href=\"https:\/\/plaza.umin.ac.jp\/sawamura\/wp\/wp-content\/uploads\/2015\/11\/radinecrosiscarbon1.jpg\"><img loading=\"lazy\" decoding=\"async\" class=\"alignleft size-medium wp-image-10834\" src=\"https:\/\/plaza.umin.ac.jp\/sawamura\/wp\/wp-content\/uploads\/2015\/11\/radinecrosiscarbon1-293x300.jpg\" alt=\"\" width=\"293\" height=\"300\" srcset=\"https:\/\/plaza.umin.ac.jp\/sawamura\/wp\/wp-content\/uploads\/2015\/11\/radinecrosiscarbon1-293x300.jpg 293w, https:\/\/plaza.umin.ac.jp\/sawamura\/wp\/wp-content\/uploads\/2015\/11\/radinecrosiscarbon1-550x563.jpg 550w, https:\/\/plaza.umin.ac.jp\/sawamura\/wp\/wp-content\/uploads\/2015\/11\/radinecrosiscarbon1.jpg 709w\" sizes=\"auto, (max-width: 293px) 100vw, 293px\" \/><\/a><a href=\"https:\/\/plaza.umin.ac.jp\/sawamura\/wp\/wp-content\/uploads\/2015\/11\/radinecrosiscarbon2.jpg\"><img loading=\"lazy\" decoding=\"async\" class=\"alignleft size-medium wp-image-10835\" src=\"https:\/\/plaza.umin.ac.jp\/sawamura\/wp\/wp-content\/uploads\/2015\/11\/radinecrosiscarbon2-298x300.jpg\" alt=\"\" width=\"298\" height=\"300\" srcset=\"https:\/\/plaza.umin.ac.jp\/sawamura\/wp\/wp-content\/uploads\/2015\/11\/radinecrosiscarbon2-298x300.jpg 298w, https:\/\/plaza.umin.ac.jp\/sawamura\/wp\/wp-content\/uploads\/2015\/11\/radinecrosiscarbon2-200x200.jpg 200w, https:\/\/plaza.umin.ac.jp\/sawamura\/wp\/wp-content\/uploads\/2015\/11\/radinecrosiscarbon2-550x554.jpg 550w, https:\/\/plaza.umin.ac.jp\/sawamura\/wp\/wp-content\/uploads\/2015\/11\/radinecrosiscarbon2-144x144.jpg 144w, https:\/\/plaza.umin.ac.jp\/sawamura\/wp\/wp-content\/uploads\/2015\/11\/radinecrosiscarbon2.jpg 709w\" sizes=\"auto, (max-width: 298px) 100vw, 298px\" \/><\/a><\/p>\n<p>\u982d\u84cb\u5e95\u306e\u810a\u7d22\u816b\u518d\u767a\u306e\u305f\u3081\u306b\u70ad\u7d20\u30a4\u30aa\u30f3\u7dda 60\u30b0\u30ec\u30a416\u5206\u5272\u306e\u6cbb\u7642\u3092\u53d7\u3051\u307e\u3057\u305f\u30025\u5e74\u5f8c\u306b\u4e21\u5074\u306e\u5074\u982d\u8449\u306e\u8133\u58ca\u6b7b\u304c\u751f\u3058\u307e\u3057\u305f\u3002\u305d\u306e\u305f\u3081\u306b\u9ad8\u5ea6\u306e\u9ad8\u6b21\u8133\u6a5f\u80fd\u969c\u5bb3\u3068\u306a\u308a\u307e\u3057\u305f\u3002\u4e21\u5074\u306e\u6d77\u99ac\uff08\u9ec4\u8272\u3044\u77e2\u5370\uff09\u306e\u58ca\u6b7b\u306e\u305f\u3081\u306b\u8a18\u61b6\u304c\u5168\u304f\u3067\u304d\u307e\u305b\u3093\u3002\u3067\u3082\u3057\u304b\u3057\uff0c\u3053\u306e\u60a3\u8005\u3055\u3093\u306f\u91cd\u7c92\u5b50\u7dda\u6cbb\u7642\u3092\u53d7\u3051\u306a\u3051\u308c\u3070\u816b\u760d\u518d\u767a\u3067\u4ea1\u304f\u306a\u3063\u3066\u3044\u305f\u3068\u79c1\u306f\u8003\u3048\u3066\u3044\u307e\u3059<\/p>\n<p><img loading=\"lazy\" decoding=\"async\" class=\"alignleft size-medium wp-image-10836\" src=\"https:\/\/plaza.umin.ac.jp\/sawamura\/wp\/wp-content\/uploads\/2015\/11\/radinecrosiscarbon3-295x300.jpg\" alt=\"\" width=\"295\" height=\"300\" srcset=\"https:\/\/plaza.umin.ac.jp\/sawamura\/wp\/wp-content\/uploads\/2015\/11\/radinecrosiscarbon3-295x300.jpg 295w, https:\/\/plaza.umin.ac.jp\/sawamura\/wp\/wp-content\/uploads\/2015\/11\/radinecrosiscarbon3-550x559.jpg 550w, https:\/\/plaza.umin.ac.jp\/sawamura\/wp\/wp-content\/uploads\/2015\/11\/radinecrosiscarbon3.jpg 709w\" sizes=\"auto, (max-width: 295px) 100vw, 295px\" \/><br \/>\n\u5de6\u5185\u9838\u52d5\u8108\u304c\u70ad\u7d20\u7dda\u88ab\u7206\u3057\u305f\u305f\u3081\u306b\u9589\u585e\u3057\u3066\u3044\u307e\u3059\u3002<\/p>\n<p>\u91cd\u7c92\u5b50\u7dda\u306f\u9ad8\u5ea6\u306e\u60aa\u6027\u816b\u760d\u3092\u3084\u3063\u3064\u3051\u308b\u5f37\u529b\u306a\u6cbb\u7642\u3067\u3042\u308b\u53cd\u9762\uff0c\u3053\u306e\u3088\u3046\u306b\u8133\u3084\u52d5\u8108\u304c\u88ab\u7206\u3059\u308c\u3070\u305d\u306e\u7d44\u7e54\u3082\u7834\u58ca\u3055\u308c\u3066\u3057\u307e\u3044\u307e\u3059\u3002\u60aa\u6027\u816b\u760d\u3092\u7834\u58ca\u3067\u304d\u308b\u5f37\u529b\u306a\u7c92\u5b50\u7dda\u6cbb\u7642\u306f\uff0c\u305d\u306e\u5468\u56f2\u306e\u795e\u7d4c\u7d44\u7e54\u3082\u304b\u307e\u308f\u305a\u7834\u58ca\u3059\u308b\u6cbb\u7642\u3067\u3042\u308b\u3068\u3082\u8a00\u3048\u307e\u3059\u3002<\/p>\n<h5>\u6587\u732e<\/h5>\n<h4>\u967d\u5b50\u7dda\u6cbb\u7642\u306f\u5f93\u6765\u306e\u653e\u5c04\u7dda\u6cbb\u7642\u3068\u6bd4\u8f03\u3057\u3066\u751f\u5b58\u671f\u9593\u3092\u5ef6\u9577\u3057\u306a\u3044<\/h4>\n<p>Muroi A: Proton therapy for newly diagnosed pediatric diffuse intrinsic pontine glioma. <span class=\"docsum-journal-citation full-journal-citation\">Childs Nerv Syst. 2020<br \/>\n\u7b51\u6ce2\u5927\u5b66\u304b\u3089\u306e\u5831\u544a\u3067\u3059\u300212\u4f8b\u306eDIPG\u306e\u5b50\u4f9b\u306b54Gy30\u5206\u5272\u306e\u967d\u5b50\u7dda\u6cbb\u7642\u304c\u884c\u308f\u308c\u307e\u3057\u305f\u3002\u7d50\u679c\uff0cOS \u751f\u5b58\u671f\u9593\u306e\u5ef6\u9577\u306f\u5f97\u3089\u308c\u307e\u305b\u3093\u3067\u3057\u305f\u3002<\/span><\/p>\n<h4>65\u6b73\u4ee5\u4e0a\u306e\u521d\u767a\u81a0\u82bd\u816b\u306b\u5bfe\u3059\u308b\u5c11\u5206\u5272\u30fb\u77ed\u671f\u9593\u967d\u5b50\u7dda\u6cbb\u7642\u306e\u52b9\u679c<\/h4>\n<p>Vora S: Short-course hypofractionated proton beam therapy, incorporating\u00a0<sup>18<\/sup>F-DOPA PET and contrast-enhanced MRI targeting, for patients aged 65 years and older with newly diagnosed glioblastoma: a single-arm phase 2 trial. Lancet Oncol 2024<br \/>\nMayo\u30af\u30ea\u30cb\u30c3\u30af\u3067\u884c\u308f\u308c\u305f\u81e8\u5e8a\u7b2c2\u76f8\u8a66\u9a13\u3067\u3059\u3002\u653e\u5c04\u7dda\u6cbb\u7642\u306e\u30bf\u30fc\u30b2\u30c3\u30c8\u306f\uff0c\u00a0<sup>18<\/sup>F-DOPA PET \u3068\u30ac\u30c9\u30ea\u30cb\u30a6\u30e0\u3067\u5897\u5f37\u3055\u308c\u308b\u90e8\u5206\u306b\u7d5e\u3063\u3066\u6c7a\u3081\u3089\u308c\u307e\u3057\u305f\u3002\u967d\u5b50\u7dda\u304c\u4f7f\u7528\u3055\u308c\uff0c\uff15\u56de\u304b\u308910\u56de\u306e\u5c11\u5206\u5272\u3067\u7167\u5c04\u3055\u308c\u3066\u3044\u307e\u3059\u300265\u4f8b\u306e\u60a3\u8005\u3055\u3093\u304c\u767b\u9332\u3055\u308c\uff0c1\u5e74\u751f\u5b58\u7387\u306f56%\uff0c\u751f\u5b58\u671f\u9593\u4e2d\u592e\u5024\u306f13.1\u30f6\u6708\u3067\u3057\u305f\u3002\u904e\u53bb\u306e\u81e8\u5e8a\u7b2c3\u76f8\u8a66\u9a13\u306e\u751f\u5b58\u671f\u95936-9\u30f6\u6708\u3068\u6bd4\u8f03\u3059\u308c\u3070\u3068\u3066\u3082\u826f\u3044\u6210\u7e3e\u3067\uff0c\u6cbb\u7642\u5f8c\u306e\u751f\u6d3b\u306e\u8cea\u3082\u826f\u597d\u3067\u3042\u308b\u3068\u5831\u544a\u8005\u306f\u7d50\u8ad6\u3057\u3066\u3044\u307e\u3059\u3002\u3067\u3059\u304c\uff0c\u75c7\u4f8b\u6570\u3082\u3068\u3066\u3082\u5c11\u306a\u304f\u751f\u5b58\u671f\u9593\u306e\u5ef6\u9577\u3082\u7121\u4f5c\u70ba\u8a66\u9a13\u3067\u306f\u306a\u3044\u306e\u3067\uff0c\u4fe1\u3074\u3087\u3046\u6027\u306b\u306f\u6b20\u3051\u307e\u3059\u3002<\/p>\n<h4>\u5c0f\u5150\u3078\u306e\u967d\u5b50\u7dda\u6cbb\u7642\u3067\u306f\u8133\u5e79\u90e8\u640d\u50b7\u30ea\u30b9\u30af\u306f\u4f4e\u3044\uff0c\u5f93\u6765\u306e\u653e\u5c04\u7dda\u3068\u540c\u69d8\u3067\u3042\u308b<\/h4>\n<p><span class=\"al-author-name-more js-flyout-wrap\">Upadhyay R:\u00a0<\/span>Quantifying the risk and dosimetric variables of symptomatic brainstem injury after proton beam radiation in pediatric brain tumors. Neuro-Oncol 2022<br \/>\nbrainstem Dmean &gt;30 Gy and\/or Dmax &gt;50.4 Gy\u4ee5\u4e0a\u306e\u967d\u5b50\u7dda\u7167\u5c04\u53d7\u3051\u305f20\u6b73\u4ee5\u4e0b\u306e468\u4eba\u306e\u60a3\u5150\u304c\u8abf\u67fb\u3055\u308c\u307e\u3057\u305f\u3002\u753b\u50cf\u4e0a\u306e\u5909\u5316\u306b\u52a0\u3048\uff0c\u8133\u795e\u7d4c\u9ebb\u75fa\uff0c\u5931\u8abf\uff0c\u9ebb\u75fa\u306a\u3069\u306e\u60aa\u5316\u304c\u751f\u3058\u305f\u4f8b\u3092\u8133\u5e79\u969c\u5bb3 brainstem injury \u3068\u8a55\u4fa1\u3057\u3066\u3044\u307e\u3059\u3002\u5e74\u9f62\u4e2d\u592e\u5024\u306f6.3\u6b73\uff0c\u7dda\u91cf\u4e2d\u592e\u5024\u306f54\u30b0\u30ec\u30a4\u3067\u3059\u300215\u4f8b (3.2%)\u3067\u8133\u5e79\u969c\u5bb3\u304c\u767a\u751f\u3057\uff0c\u4e2d\u592e\u5024\u306f\u7167\u5c04\u5f8c4\u30f6\u6708\u3067\u3059\u3002\u30b0\u30ec\u30fc\u30c92, 3, 4, 5\u306e\u8133\u5e79\u90e8\u969c\u5bb3\u306f\uff0c\u305d\u308c\u305e\u308c7, 5, 1, 2\u540d\u3067\u3059\u3002\u7121\u75c7\u5019\u6027\u306e\u753b\u50cf\u4e0a\u5909\u5316\u306f51\u4f8b (11%)\u306b\u751f\u3058\u307e\u3057\u305f\u30023\u6b73\u4ee5\u4e0b\uff0c\u5973\u5150\uff0cATRT\uff0c\u5e79\u7d30\u80de\u6551\u63f4\u3068\u5927\u91cf\u5316\u5b66\u7642\u6cd5\u306a\u3069\u304c\u30ea\u30b9\u30af\u30d5\u30a1\u30af\u30bf\u30fc\u3067\u3057\u305f\u3002\u7dda\u91cf\u5236\u7d04\u3092\u884c\u306a\u3063\u305f\u5f8c\u306b\u306f\u8133\u5e79\u969c\u5bb3\u304c\u6e1b\u5c11\u3057\u305f\u3068\u3044\u3046\u3053\u3068\u3067\u3059\u3002\u5f93\u6765\u306ephton \u653e\u5c04\u7dda\u6cbb\u7642\u306b&#8221;\u5339\u6575\u3059\u308b comparable to &#8221; \u7a0b\u5ea6\u306b\u4f4e\u4fb5\u8972\u3060\u3068\u7d50\u8ad6\u3057\u3066\u3044\u307e\u3059\u3002<\/p>\n<h4>\u81a0\u82bd\u816b\u306b\u5bfe\u3059\u308b\u967d\u5b50\u7dda\u3068IMRT\u653e\u5c04\u7dda\u6cbb\u7642<\/h4>\n<p><span class=\"al-author-name js-flyout-wrap\">Brown PD:\u00a0<\/span>A Prospective Phase II Randomized Trial of Proton Radiotherapy vs. Intensity Modulated Radiotherapy for Patients with Newly Diagnosed Glioblastoma, Neuro-Oncol 2021<br \/>\n\u967d\u5b50\u7dda\u6cbb\u7642\u3068IMRT\u3068\u3044\u3046\u5f93\u6765\u306e\u653e\u5c04\u7dda\u6cbb\u7642\u3092\u7528\u3044\u3066\uff0c\u7167\u5c04\u306b\u3088\u308b\u8a8d\u77e5\u6a5f\u80fd\u306e\u4f4e\u4e0b\u304c\u6bd4\u8f03\u3055\u308c\u307e\u3057\u305f\u300267\u4eba\u306e\u60a3\u8005\u3055\u3093\u3067\u81e8\u5e8a\u7b2c\uff12\u76f8\u8a66\u9a13\u304c\u884c\u308f\u308c\uff0c\u8a8d\u77e5\u6a5f\u80fd\u306e\u6e29\u5b58\u306b\u6709\u610f\u306a\u3055\u306f\u306a\u304b\u3063\u305f\u3068\u306e\u7d50\u8ad6\u3067\u3059\u3002\u81a0\u82bd\u816b\u306b\u967d\u5b50\u7dda\u6cbb\u7642\u3092\u884c\u3046\u30e1\u30ea\u30c3\u30c8\u306f\u306f\u3063\u304d\u308a\u3057\u307e\u305b\u3093\u3002<\/p>\n<h4>\u5c0f\u5150\u8133\u816b\u760d\u306b\u5bfe\u3059\u308b\u967d\u5b50\u7dda\u6cbb\u7642\u306e\u5229\u70b9<\/h4>\n<p class=\"title hypothesis_container\"><span class=\"sciprofiles-link__name\">D<\/span><span class=\"sciprofiles-link__name\">ell\u2019Oro M:\u00a0<\/span>Influence of Target Location, Size, and Patient Age on Normal Tissue Sparing- Proton and Photon Therapy in Paediatric Brain Tumour Patient-Specific Approach. Cancers 2020<br \/>\n9\u6b73\u4ee5\u4e0b\u306e\u5c0f\u5150\u306e\u30c6\u30f3\u30c8\u4e0a\u816b\u760d\u306b\u967d\u5b50\u7dda\u3092\u7528\u3044\u308b\u3068\u4e0b\u5782\u4f53\u306e\u88ab\u66dd\u91cf\u304c\u6e1b\u91cf\u3055\u308c\u307e\u3059\u3002\u9ac4\u82bd\u816b\u306a\u3069\u306e\u30c6\u30f3\u30c8\u4e0b\u816b\u760d\u3067\u306f\u8996\u8def\u3092\u542b\u3081\u305f\u8133\u7d44\u7e54\u3078\u306e\u88ab\u66dd\u91cf\u304c\u4f4e\u6e1b\u3067\u304d\u308b\u3068\u3044\u3046\u3053\u3068\u3067\u3059\u3002<\/p>\n<h4 class=\"cit\">\u9ac4\u82bd\u816b\u306e\u4f4e\u30ea\u30b9\u30af\u7fa4\u3067\u306f\uff0c\u967d\u5b50\u7dda\u306e\u307b\u3046\u304c\u77e5\u80fd\u4e88\u5f8c\u304c\u826f\u3044<\/h4>\n<p><span class=\"highlight\">Kahalley LS: Superior<\/span> <span class=\"highlight\">Intellectual<\/span> <span class=\"highlight\">Outcomes<\/span> <span class=\"highlight\">After<\/span> <span class=\"highlight\">Proton<\/span> <span class=\"highlight\">Radiotherapy<\/span> <span class=\"highlight\">Compared<\/span> With <span class=\"highlight\">Photon<\/span> <span class=\"highlight\">Radiotherapy<\/span>for <span class=\"highlight\">Pediatric<\/span> <span class=\"highlight\">Medulloblastoma<\/span>. <span role=\"menubar\">J Clin Oncol.<\/span> 2019<br \/>\n\u9577\u304f\u8b70\u8ad6\u304c\u3042\u3063\u305f\u547d\u984c\u306e\u7b54\u3048\u304b\u3082\u3057\u308c\u307e\u305b\u3093\u30022007\u5e74\u304b\u30892018\u5e74\u306b\u6cbb\u7642\u3055\u308c\u305f\u9ac4\u82bd\u816b\u306b\uff0c37\u4eba\u306b\u967d\u5b50\u7dda\u304c\uff0c42\u4eba\u306b\u5149\u5b50\u7dda\uff08photon radiotherepy, \u65e7\u6765\u306e\u653e\u5c04\u7dda\u6cbb\u7642\uff09\u304c\u7528\u3044\u3089\u308c\u307e\u3057\u305f\u3002\u8133\u810a\u9ac4\u7dda\u91cf\u4e2d\u592e\u5024\u306f\u540c\u305823.4Gy\u3067\uff0c\u5e73\u5747\u5e74\u9f628.6\u6b73\uff0c\u5e73\u5747\u8ffd\u8de1\u671f\u9593\u306f4.3\u5e74\u3067\u3059\u3002<span style=\"color: #000080;\"><strong>\u65e7\u6765\u306e\u653e\u5c04\u7dda\u6cbb\u7642\u3067\u306f\u8a8d\u77e5\u6a5f\u80fd\u306f\u4f4e\u4e0b\u3057\u307e\u3057\u305f\u304c\uff0c\u967d\u5b50\u7dda\u3067\u306fstable scores\u3067\u3042\u3063\u305f<\/strong><\/span>\u305d\u3046\u3067\u3059\u3002\u305d\u306e\u307e\u307e\u53d7\u3051\u53d6\u308c\u3070\u76ee\u7acb\u3063\u305f\u77e5\u80fd\u4f4e\u4e0b\u306f\u306a\u3044\u3068\u8a33\u305b\u307e\u3059\u3002\u3053\u306e\u8ad6\u6587\u306f\u4eca\u5f8c\u306e\u653e\u5c04\u7dda\u6cbb\u7642\u306b\u5bfe\u3057\u3066\u5927\u304d\u306a\u30a4\u30f3\u30d1\u30af\u30c8\u3092\u3082\u3064\u3082\u306e\u3067\u3059\u3002<br \/>\n\u300c\u89e3\u8aac\u300d\u8457\u8005\u306f\uff0cprocessing speed\u306f\u967d\u5b50\u7dda\u3067\u3082\u4f4e\u4e0b\u3057\u305f\u3068\u5f37\u8abf\u3057\u3066\u3044\u307e\u3059\u3002\u539f\u767a\u5de3\u5468\u56f2\u306e\u5c0f\u8133\u306b\u306f\u540c\u3058\u9ad8\u7dda\u91cf\u304c\u5165\u308a\u307e\u3059\u306e\u3067\uff0c\u967d\u5b50\u7dda\u306b\u304a\u3044\u3066\u3082\uff0c\u5c0f\u8133\u6a5f\u80fd\u3092\u4ecb\u3059\u308b\u8a8d\u77e5\u6a5f\u80fd\u3068\u3057\u3066\u306eprocessing speed\u306f\u4f4e\u4e0b\u3059\u308b\u3068\u7406\u89e3\u3055\u308c\u307e\u3059\u3002\u6ce8\u610f\u3057\u305f\u3044\u306e\u306f\uff0c\u6cbb\u7642\u5bfe\u8c61\u3068\u306a\u3063\u305f\u5e74\u9f62\u304c\u9ac4\u82bd\u816b\u306b\u3057\u3066\u306f\u6bd4\u8f03\u7684\u9ad8\u3044\u3053\u3068\uff0c\u307e\u305f\u5bfe\u8c61\u304c\u4f4e\u30ea\u30b9\u30af\u7fa4\u3067\u3042\u3063\u305f\u3068\u3044\u3046\u9650\u5b9a\u6761\u4ef6\u3067\u3059\u3002\u307e\u305f\u8133\u810a\u9ac4\u7167\u5c04\u306f\u540c\u3058\u7dda\u91cf\u304c\u5165\u3063\u3066\u3044\u307e\u3059\u306e\u3067\uff0c\u8133\u810a\u9ac4\u7167\u5c04\u304c23.4Gy\u3068\u3044\u3046\u4f4e\u7dda\u91cf\u6761\u4ef6\u306b\u304a\u3044\u3066\u6210\u7acb\u3057\u5f97\u308b\u6cbb\u7642\u6210\u7e3e\u3067\u3059\u3002<\/p>\n<h4>\u967d\u5b50\u7dda\u6cbb\u7642\u306e\u65b9\u304c\u7532\u72b6\u817a\u6a5f\u80fd\u4f4e\u4e0b\u75c7\u5c11\u306a\u3044\u304b\uff1f\u3000\u306f\u3063\u304d\u308a\u3057\u3066\u3044\u306a\u3044<\/h4>\n<p>Bielamowicz K: Hypothyroidism after craniospinal irradiation with proton or photon <span class=\"highlight\">therapy<\/span> in patients with <span class=\"highlight\">medulloblastoma<\/span>.\u00a0<span role=\"menubar\">Pediatr Hematol Oncol.<\/span> 2018<br \/>\n\u9ac4\u82bd\u816b\u3067\u8133\u810a\u9ac4\u7167\u5c04\u3092\u53d7\u3051\u305f\u5b50\u4f9b\u305f\u3061\u306e\u7532\u72b6\u817a\u6a5f\u80fd\u304c\u8ffd\u8de1\u3055\u308c\u307e\u3057\u305f\u3002\u8ffd\u8de1\u671f\u9593\u306f\uff0c\u901a\u5e38\u306eX\u7dda XRT \u306f9.6\u5e74\uff0c\u967d\u5b50\u7dda PRT \u30673.8\u5e74\u3067\u3057\u305f\u3002\u539f\u767a\u6027\u7532\u72b6\u817a\u6a5f\u80fd\u4f4e\u4e0b\u75c7\u306f\uff0cXRT\u306712\/54 (22.2%) \u4eba\uff0cPRT\u30673\/41 (7.3%)\u4eba\u3067\u3057\u305f\u3002\u4e2d\u67a2\u6027\u7532\u72b6\u817a\u6a5f\u80fd\u4f4e\u4e0b\u75c7\u306f\uff0cXRT\u306713\/54 (24.0%) \u4eba\uff0cPRT\u3067 4\/41 (9.8%) \u4eba\u3067\u3057\u305f\u3002\u3044\u305a\u308c\u306e\u6570\u5b57\u3082\u967d\u5b50\u7dda\u6cbb\u7642\u306e\u65b9\u304c\u512a\u3063\u3066\u3044\u307e\u3059\u3002\u3067\u3082\u7d50\u8ad6\u3067\u306f\uff0c\u7d71\u8a08\u5b66\u7684\u306b\u6709\u610f\u306a\u5dee\u306f\u306a\u3044\u3068\u3055\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n<h4>2018\u5e74ASTRO\u3067\u306e\u5b66\u4f1a\u767a\u8868<\/h4>\n<p>\u967d\u5b50\u7dda\u6cbb\u7642\u3068X\u7dda\u6cbb\u7642\u3092\u53d7\u3051\u305f125\u4eba\u306e\u5b50\u4f9b\u304c\u8ffd\u8de1\u8abf\u67fb\u3055\u308c\u307e\u3057\u305f\u3002\u8a3a\u65ad\u5e74\u9f62\u4e2d\u592e\u5024\u306f7\u6b73\uff0c4\u5e74\u307b\u3069\u306e\u7d4c\u904e\u3092\u898b\u308b\u3068\uff0c\u967d\u5b50\u7dda\u6cbb\u7642\u306e\u65b9\u304cfull-scale IQ (10.6), processing speed (12.6) , parent-reported practical function (13.8)\u3067\uff0cX\u7dda\u306b\u512a\u3063\u305f\u3068\u306e\u3053\u3068\u3067\u3059\u3002Northwestern Medicine\u306e\u653e\u5c04\u7dda\u6cbb\u7642\u79d1\u306e\u30ec\u30b8\u30c7\u30f3\u30c8\u306e\u767a\u8868\u3067\uff0c\u5f8c\u65b9\u8996\u7684\u306a\u5206\u6790\u3067\u3059\u3002\u3053\u306e\u30c7\u30fc\u30bf\u306f\u9d5c\u5451\u307f\u306b\u306f\u3067\u304d\u306a\u3044\u304b\u3082\u3057\u308c\u307e\u305b\u3093\u3002<\/p>\n<h4>\u9ac4\u82bd\u816b\u306e\u967d\u5b50\u7dda\u6cbb\u7642<\/h4>\n<p>Yock TI et al. Long-term toxic effects of proton radiotherapy for\u00a0paediatric medulloblastoma: a phase 2 single-arm study. Lancet Oncology Published online January 29, 2016<br \/>\n\u30dc\u30b9\u30c8\u30f3MGH\u304b\u3089\u306e\u5831\u544a\u3067\uff0c2003\u5e74\u304b\u30892009\u5e74\u306b59\u4eba\u306e\u9ac4\u82bd\u816b\u306e\u6cbb\u7642\u6210\u7e3e\u3067\u3059\u300214\u4f8b\u306e\u9ad8\u30ea\u30b9\u30af\u7fa4\u306e\u60a3\u5150\u304c\u542b\u307e\u308c\u3066\u3044\u307e\u3059\u3002\u967d\u5b50\u7dda\u3067\u8133\u810a\u9ac418\u201336 Gy (GyRBE) (1\u00b78 GyRBE per fraction)\u3068\u5c40\u6240\u7167\u5c04\u304c\u4f7f\u7528\u3055\u308c\u307e\u3057\u305f\u3002\u5168\u54e1\u304c\u5316\u5b66\u7642\u6cd5\u3092\u53d7\u3051\u3066\u304a\u308a\uff0c\u8133\u810a\u9ac4\u7dda\u91cf\u4e2d\u592e\u5024\u306f23.4Gy\uff0c\u5c40\u6240\u306f54Gy\u3067\u3057\u305f\u3002\u751f\u5b58\u8005\u5e73\u5747\u8ffd\u8de1\u671f\u9593\u306f7\u5e74\u3067\u3059\u300245\u4eba\u4e2d\u306e4\u4eba(9%)\u3067\u4e21\u5074\u306e\u8074\u529b\u4f4e\u4e0b(grade 3-4)\u304c\u751f\u3058\uff0c3\u4eba\u3067\u7247\u5074\u306e\u8074\u529b\u4f4e\u4e0b\u304c\u751f\u3058\u307e\u3057\u305f\u30025\u5e74\u3067\u306e\u7d2f\u7a4d\u5272\u5408\u3067\u306f16%\u3067\u3057\u305f\u30025\u5e74\u8ffd\u8de1\u671f\u9593\u3067FIQ\u304c\u5e74\u5e73\u57471.5 point\u4f4e\u4e0b\u3057\u307e\u3057\u305f\u3002\u5185\u5206\u6ccc\u6a5f\u80fd\u306f55%\u3067\u4f4e\u4e0b\u3057\u3066\u3044\u3066\uff0c\u6210\u9577\u30db\u30eb\u30e2\u30f3\u6b20\u640d\u75c7\u304c\u983b\u5ea6\u3068\u3057\u3066\u9ad8\u304b\u3063\u305f\u3068\u306e\u3053\u3068\u3067\u3059\u30025\u5e74\u5168\u751f\u5b58\u5272\u5408\u306f83%(95%CI 67-88)\u3068\u63a8\u5b9a\u3055\u308c\u307e\u3057\u305f\u3002\u967d\u5b50\u7dda\u3067\uff0c\u65e7\u6765\u306e\u653e\u5c04\u7dda\u6cbb\u7642\u3068\u540c\u7b49\u306e\u751f\u5b58\u5272\u5408\u3092\u5f97\u3089\u308c\u308b\u3068\u306e\u7d50\u8ad6\u3067\u3059\u3002<br \/>\n\u300cCCLG\u306e\u30b3\u30e1\u30f3\u30c8\u300d<br \/>\n\u4e2d\u77ed\u671f\u306e\u89b3\u5bdf\u671f\u9593\u306b\u304a\u3044\u3066\uff0c\u967d\u5b50\u7dda\u306b\u3088\u308b\u751f\u5b58\u5272\u5408\u3068\u526f\u4f5c\u7528\u306f\u65e7\u6765\u306e\u653e\u5c04\u7dda\u6cbb\u7642\u3068\u540c\u7b49\u3067\u3042\u308b\u8a55\u4fa1\u3057\u3066\u3044\u307e\u3059\u3002\u7406\u8ad6\u7684\u671f\u5f85\u304c\u3042\u308b\u3082\u306e\u306e\u305d\u308c\u306f\u307e\u3060\u8a3c\u660e\u306b\u306f\u81f3\u3063\u3066\u3044\u307e\u305b\u3093\u3002\u30e1\u30c7\u30a3\u30a2\u3067\u5831\u9053\u3055\u308c\u305f\u3082\u306e\u306f\uff0c\u8ad6\u6587\u306e\u8457\u8005\u306b\u3088\u3063\u3066\u66f8\u304b\u308c\u305f\u7d50\u8ad6\u306b\u5c3e\u3072\u308c\u304c\u3064\u3044\u3066\u3044\u308b\u3088\u3046\u3067\uff0c\u4e00\u90e8\u306e\u5831\u9053\u306e\u967d\u5b50\u7dda\u306b\u5bfe\u3059\u308b\u71b1\u6c17\u306b\u8b66\u544a\u3092\u767a\u3057\u3066\u3044\u307e\u3059\u3002<\/p>\n<h4>\u967d\u5b50\u7dda\u6cbb\u7642\u3068\u77e5\u80fd\u4f4e\u4e0b<\/h4>\n<p>Kahalley LS, et al.: Comparing Intelligence Quotient Change After Treatment With Proton Versus Photon Radiation Therapy for Pediatric Brain Tumors. J Clin Oncol 34:1043-92, 2016<br \/>\n\u967d\u5b50\u7dda\u3092\u53d7\u3051\u305f\u5b50\u4f9b130\u4eba\u3068\u5f93\u6765\u306e\u30ac\u30f3\u30de\u7dda\u7167\u5c04 photon radiation \u3092\u53d7\u3051\u305f\u5b50\u4f9b90\u4eba\u306e\u77e5\u80fd\u304c\u6bd4\u8f03\u3055\u308c\u307e\u3057\u305f\u3002\u967d\u5b50\u7dda\u3067\u306fIQ\u306b\u5909\u5316\u306f\u3042\u308a\u307e\u305b\u3093\u3067\u3057\u305f\u304c\uff0c\u5f93\u6765\u306e\u653e\u5c04\u7dda\u3067\u306f\uff11\u5e74\u9593\u306bIQ\u304c 1.1 \u4f4e\u4e0b\u3057\u307e\u3057\u305f\u3002\u3057\u304b\u3057\uff0c\u4f4e\u4e0b\u50be\u5411\u306b\u6709\u610f\u306a\u5dee\u306f\u3042\u308a\u307e\u305b\u3093\u3067\u3057\u305f\u3002\u7d50\u8ad6\u3068\u3057\u3066\uff0c\u967d\u5b50\u7dda\u306e\u307b\u3046\u304c\u30ac\u30f3\u30de\u7dda\u3088\u308a\u3082\uff0c\u8a8d\u77e5\u6a5f\u80fd\u306e\u6e29\u5b58\u3067\u304d\u308b\u304b\u3069\u3046\u304b\u306f\u4e0d\u660e\u3067\u3042\u308b\u3068\u3057\u3066\u307e\u3059\u3002<\/p>\n<h4>\u5c0f\u5150\u8133\u816b\u760d\u3078\u306e\u967d\u5b50\u7dda\u6cbb\u7642\u3068\u8a8d\u77e5\u6a5f\u80fd<\/h4>\n<p>Pulsifer MB, et al.: Early Cognitive Outcomes Following Proton Radiation in Pediatric Patients With Brain and Central Nervous System Tumors. Int J Radiat Oncol Biol Phys 93:400-407, 2015<br \/>\nMGH\u304b\u3089\u306e\u5831\u544a\u3067\u3059\u3002\uff16\u6b73\u4ee5\u4e0a\u306e60\u4eba\u306e\u60a3\u5150\uff08\u9ac4\u82bd\u816b\uff0c\u30b0\u30ea\u30aa\u30fc\u30de\uff0c\u982d\u84cb\u54bd\u982d\u816b\uff0c\u4e0a\u8863\u816b\u306a\u3069\uff09\u304c\u967d\u5b50\u7dda\u6cbb\u7642\u3092\u53d7\u3051\u307e\u3057\u305f\u3002\u8133\u810a\u9ac4\u7167\u5c04\u304c47%\u3067\u5c40\u6240\u7167\u5c04\u304c53%\u3067\u3057\u305f\u3002\u5e73\u5747\u5e74\u9f62\u306f12\u6b73\u3067\u5e73\u5747\u8ffd\u8de1\u671f\u9593\u306f2.5\u5e74\u3067\u3059\u3002\u30a6\u30a7\u30af\u30b9\u30e9\u30fcFIQ\u691c\u67fb,\u00a0Verbal Comprehension, Perceptual Reasoning\/Organization, Working Memory\u3067\u306f\u6709\u610f\u306a\u4f4e\u4e0b\u306f\u751f\u3058\u306a\u304b\u3063\u305f\u3068\u306e\u3053\u3068\u3067\u3059\uff08\u307b\u3093\u3068??\uff09\u3002\u3057\u304b\u3057\uff0c12\u6b73\u4ee5\u4e0b\u3067\u306fProcessing Speed scores\u306e\u4f4e\u4e0b\u304c\u76ee\u7acb\u3063\u3066\u6709\u610f\u3067\u3057\u305f (mean 5.2 points)\u3002<br \/>\n\u300c\u89e3\u8aac\u300d\u967d\u5b50\u7dda\u6cbb\u7642\u3067\u8a8d\u77e5\u6a5f\u80fd\u306e\u4f4e\u4e0b\u304c\u9632\u3052\u308b\u3068\u8003\u3048\u3089\u308c\u304b\u306a\u308a\u671f\u5f85\u3055\u308c\u3066\u3044\u307e\u3059\u3002\u3057\u304b\u3057\uff0c\u967d\u5b50\u7dda\u6cbb\u7642\u3067\u5c0f\u5150\u306e\u8a8d\u77e5\u6a5f\u80fd\u304c\u5b88\u308c\u305f\u304b\u3069\u3046\u304b\u3068\u3044\u3046\u8a3c\u62e0\u306f\u76f8\u5909\u308f\u3089\u305a\u3042\u308a\u307e\u305b\u3093\u3002\u3053\u306e\u5831\u544a\u3082\u7d4c\u904e\u89b3\u5bdf\u671f\u9593\u304c\u77ed\u304f\uff0c\u8133\u810a\u9ac4\u7167\u5c04\u3084\u5927\u8133\u3084\u5c0f\u8133\u306e\u90e8\u5206\u7167\u5c04\u304c\u6df7\u5728\u3059\u308b\u3082\u306e\u3067\uff0c\u7d50\u8ad6\u306b\u306f\u5168\u304f\u3044\u305f\u308a\u307e\u305b\u3093\u3002<\/p>\n<h4 align=\"left\">\u810a\u7d22\u816b\u306e\u967d\u5b50\u7dda\u6cbb\u7642<\/h4>\n<p>McDonald MW, et al.: Influence of Residual Tumor Volume and Radiation Dose Coverage in Outcomes for Clival Chordoma. Int J Radiat Oncol Biol Phys. 2015 Aug<br \/>\n\u30a4\u30f3\u30c7\u30a3\u30a2\u30ca\u5927\u5b66\u304b\u3089\u306e\u5831\u544a\u3067\u3059\u300239\u4eba\u306e\u60a3\u8005\u3055\u3093\u304c\u306e\u967d\u5b50\u7dda\u6cbb\u7642 (\u4e2d\u592e\u5024 77.4\u30b0\u30ec\u30a4; RBE range 70-79Gy) \u3092\u53d7\u3051\u307e\u3057\u305f\u3002\u8ffd\u8de1\u671f\u9593\u4e2d\u592e\u5024\u306f51\u30f6\u6708\u3068\u77ed\u3044\u306e\u3067\u3059\u304c\uff0c5\u5e74\u63a8\u5b9a\u5024\u3067\u306e\u816b\u760d\u30b3\u30f3\u30c8\u30ed\u30fc\u30eb\u5272\u5408\u306f69.6\uff05 (95%CI 50-89)\u3067\uff0cOS\u00a081% (95%CI 65-97)\u3067\u3059\u3002GTV\u304c\u5c0f\u3055\u3044\u65b9\u304c\u816b\u760d\u5236\u5fa1\u304c\u78ba\u5b9f\u3068\u306a\u308a\uff0c\u816b\u760d\u5358\u4f4d\u4f53\u7a4d\u3042\u305f\u308a\u306eD1cm3\u306f74.5Gy\u4ee5\u4e0a\u304c\u5fc5\u8981\u3068\u306e\u7d50\u8ad6\u3067\u3059\u3002<br \/>\n\u300c\u89e3\u8aac\u300d\u3053\u306e\u63a8\u5b9a\u5024\u304b\u3089\u306f\u967d\u5b50\u7dda\u3067\u810a\u7d22\u816b\u306e\u5897\u5927\u3092\u5236\u5fa1\u3067\u304d\u308b\u78ba\u7387\u306f50\uff05\u7a0b\u5ea6\u3068\u8aad\u307f\u53d6\u308c\u307e\u3059\u3002\u624b\u8853\u3067\u9650\u754c\u307e\u3067\u6458\u51fa\u3057\u3066\u6b8b\u5b58\u816b\u760d\u304c\u5c0f\u3055\u3044\u65b9\u304c\u967d\u5b50\u7dda\u306e\u52b9\u679c\u3082\u671f\u5f85\u3055\u308c\u308b\u3068\u3044\u3046\u3053\u3068\u304c\u8aeb\u8a00\u3055\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n<h5>\u53c2\u7167\u6587\u732e<\/h5>\n<ul>\n<li>McDonald MW, et al.: Influence of Residual Tumor Volume and Radiation Dose Coverage in Outcomes for Clival Chordoma. Int J Radiat Oncol Biol Phys. 2015 Aug<\/li>\n<li>Pulsifer MB, et al.: Early Cognitive Outcomes Following Proton Radiation in Pediatric Patients With Brain and Central Nervous System Tumors. Int J Radiat Oncol Biol Phys 93:400-407, 2015<\/li>\n<li>Yock TI et al. Long-term toxic effects of proton radiotherapy for\u00a0paediatric medulloblastoma: a phase 2 single-arm study. Lancet Oncology Published online January 29, 2016<\/li>\n<\/ul>\n","protected":false},"excerpt":{"rendered":"<p>\u5927\u5207\u306a\u3053\u3068 \u967d\u5b50\u7dda\u6cbb\u7642\u3068\u91cd\u7c92\u5b50\u7dda\u6cbb\u7642\u3068\u4e2d\u6027\u5b50\u7dda\u6cbb\u7642\u3092\u4f75\u305b\u3066\u7c92\u5b50\u7dda\u6cbb\u7642\u3068\u8a00\u3044\u307e\u3059 \u967d\u5b50\u7dda\u6cbb\u7642\u306f\u6c34\u7d20\u306e\u539f\u5b50\u6838\uff08\u967d\u5b50\uff09\u3092\u52a0\u901f\u3057\u3066\u60a3\u90e8\u306b\u5f53\u3066\u308b\u65b9\u6cd5\u3067\u3059 \u91cd\u7c92\u5b50\u7dda\u6cbb\u7642\u3068\u306f\u70ad\u7d20\u30a4\u30aa\u30f3\u3092\u52a0\u901f\u3057\u3066\u60a3\u90e8\u306b\u5f53\u3066\u308b\u65b9\u6cd5\u3067\u3059 \u7c92\u5b50\u7dda\u6cbb\u7642\u306e\u7279\u5fb4\u306f [&hellip;]<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[4],"tags":[],"class_list":["post-8197","post","type-post","status-publish","format-standard","hentry","category-braintumors"],"aioseo_notices":[],"_links":{"self":[{"href":"https:\/\/plaza.umin.ac.jp\/sawamura\/wp-json\/wp\/v2\/posts\/8197","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/plaza.umin.ac.jp\/sawamura\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/plaza.umin.ac.jp\/sawamura\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/plaza.umin.ac.jp\/sawamura\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/plaza.umin.ac.jp\/sawamura\/wp-json\/wp\/v2\/comments?post=8197"}],"version-history":[{"count":37,"href":"https:\/\/plaza.umin.ac.jp\/sawamura\/wp-json\/wp\/v2\/posts\/8197\/revisions"}],"predecessor-version":[{"id":23188,"href":"https:\/\/plaza.umin.ac.jp\/sawamura\/wp-json\/wp\/v2\/posts\/8197\/revisions\/23188"}],"wp:attachment":[{"href":"https:\/\/plaza.umin.ac.jp\/sawamura\/wp-json\/wp\/v2\/media?parent=8197"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/plaza.umin.ac.jp\/sawamura\/wp-json\/wp\/v2\/categories?post=8197"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/plaza.umin.ac.jp\/sawamura\/wp-json\/wp\/v2\/tags?post=8197"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}