{"id":6015,"date":"2014-07-13T14:57:05","date_gmt":"2014-07-13T05:57:05","guid":{"rendered":"\/sawamura\/?p=6015"},"modified":"2020-04-05T11:58:29","modified_gmt":"2020-04-05T02:58:29","slug":"newbonetumor","status":"publish","type":"post","link":"https:\/\/plaza.umin.ac.jp\/sawamura\/pediattumor\/newbonetumor\/","title":{"rendered":"\u65b0\u751f\u5150\u306e\u8133\u816b\u760d\uff0c\u907a\u4f1d\u6027\u8133\u816b\u760d\uff0c\u5bb6\u65cf\u6027\u8133\u816b\u760d"},"content":{"rendered":"<h1 align=\"left\">\u907a\u4f1d\u6027\u8133\u816b\u760d hereditary brain tumor, familial brain tumor<\/h1>\n<h5>\u5bb6\u65cf\u6027\u306b\u3042\u308b\u7279\u5b9a\u306e\u907a\u4f1d\u5b50\u306bgerm line mutation\u304c\u3042\u308a\u751f\u3058\u308b\u816b\u760d\u3067\u3059<\/h5>\n<h4><a href=\"https:\/\/plaza.umin.ac.jp\/sawamura\/braintumors\/cavernoma\/\"><strong>\u5bb6\u65cf\u6027\u6d77\u7dbf\u72b6\u8840\u7ba1\u816b\uff08\u5225\u30da\u30fc\u30b8\u306a\u306e\u3067\u3053\u3053\u3092\u30af\u30ea\u30c3\u30af\uff09<\/strong><\/a><\/h4>\n<ul>\n<li>\u8133\u3068\u810a\u9ac4\u306b\u6d77\u7dbf\u72b6\u8840\u7ba1\u816b\u304c\u591a\u767a\u3057\u307e\u3059<\/li>\n<\/ul>\n<h4><span style=\"color: #000080;\"><a style=\"color: #000080;\" href=\"\/sawamura\/braintumors\/nf-1\/\">\u795e\u7d4c\u7dda\u7dad\u816b\u75c71\u578b NF-1\uff08\u5225\u30da\u30fc\u30b8\u306a\u306e\u3067\u3053\u3053\u3092\u30af\u30ea\u30c3\u30af\uff09<\/a><\/span><\/h4>\n<ul>\n<li>\u982d\u9838\u90e8\u3084\u810a\u67f1\u7ba1\u306b\u795e\u7d4c\u9798\u816b\u304c\u591a\u767a\u3057\u307e\u3059<\/li>\n<li>\u8996\u795e\u7d4c\u306b\u6bdb\u69d8\u7d30\u80de\u6027\u661f\u7d30\u80de\u816b\u304c\u51fa\u307e\u3059<\/li>\n<\/ul>\n<h4><span style=\"color: #000080;\"><a style=\"color: #000080;\" href=\"\/sawamura\/braintumors\/nf-2\/\">\u795e\u7d4c\u7dda\u7dad\u816b\u75c72\u578b NF-2\uff08\u5225\u30da\u30fc\u30b8\u306a\u306e\u3067\u3053\u3053\u3092\u30af\u30ea\u30c3\u30af\uff09<\/a><\/span><\/h4>\n<ul>\n<li>\u4e21\u5074\u306e\u8074\u795e\u7d4c\u816b\u760d\u304c\u767a\u751f\u3057\u307e\u3059<\/li>\n<li>\u591a\u6570\u306e\u8133\u795e\u7d4c\u306b\u795e\u7d4c\u9798\u816b\u304c\u3067\u304d\u307e\u3059<\/li>\n<li>\u9ac4\u819c\u816b\u304c\u591a\u767a\u3057\u307e\u3059<\/li>\n<li>\u810a\u9ac4\u306b\u4e0a\u8863\u816b\u304c\u3067\u304d\u307e\u3059<\/li>\n<\/ul>\n<h4>\u795e\u7d4c\u9798\u816b\u75c7 schwannomatosis<\/h4>\n<ul>\n<li>\u305f\u304f\u3055\u3093\u306e\u795e\u7d4c\u9798\u816b\u304c\u8133\u795e\u7d4c\u3068\u810a\u9ac4\u795e\u7d4c\u306b\u3067\u304d\u308b\u306e\u3067\u3059\u304c\uff0cNF-2\u3068\u306f\u9055\u3044\u307e\u3059<\/li>\n<li>germ-line NF-2 gene\u306b\u5909\u7570\u304c\u3042\u308a\u307e\u305b\u3093\u304cNF-2\u306e\u4e0d\u6d3b\u5316\u306f\u307f\u3089\u308c\u307e\u3059<\/li>\n<li>\u534a\u6570\u304f\u3089\u3044\u306bSMARCB1 or LZTR1\u816b\u760d\u6291\u5236\u907a\u4f1d\u5b50\u306b\u5909\u7570\u304c\u3042\u308a\u307e\u3059<\/li>\n<li>\u307e\u308c\u306b\u9ac4\u819c\u816b\u3092\u5408\u4f75\u3057\u307e\u3059<\/li>\n<\/ul>\n<h4><span style=\"color: #000080;\"><a style=\"color: #000080;\" href=\"\/sawamura\/braintumors\/hemangioblastoma\/\">\u30d5\u30a9\u30f3\u30fb\u30d2\u30c3\u30da\u30eb\u30fb\u30ea\u30f3\u30c9\u30a6\u75c5\u3000VHL\uff08\u5225\u30da\u30fc\u30b8\u306a\u306e\u3067\u3053\u3053\u3092\u30af\u30ea\u30c3\u30af\uff09<\/a><\/span><\/h4>\n<ul>\n<li>\u5c0f\u8133\u3068\u810a\u9ac4\u306b\u8840\u7ba1\u82bd\u816b\u304c\u591a\u767a\u3057\u307e\u3059<\/li>\n<\/ul>\n<h4 align=\"left\">\u5bb6\u65cf\u6027\u5927\u8178\u817a\u816b\u75c7\u3000FAP familial adenomatous polyposis<\/h4>\n<ul>\n<li>APC\u907a\u4f1d\u5b50\u306e\u5909\u7570\u304c\u3042\u308a\u307e\u3059<\/li>\n<li>\u5927\u8178\u306b\u7121\u6570\u306e\u817a\u816b\u304c\u767a\u751f\u3057\u3066\uff0c\u3084\u304c\u3066\u764c\u5316\u3057\u307e\u3059<\/li>\n<li>\u8133\u816b\u760d\u3092\u767a\u751f\u3059\u308b\u3082\u306e\u306f\uff0c\u30bf\u30fc\u30b3\u30c3\u30c8\u75c7\u5019\u7fa4\u3068\u30ac\u30fc\u30c9\u30ca\u30fc\u75c7\u5019\u7fa4\u3068\u547c\u3070\u308c\u307e\u3059<\/li>\n<\/ul>\n<h4>\u30bf\u30fc\u30b3\u30c3\u30c8\u75c7\u5019\u7fa4 Turcot&#8217;s syndrome<\/h4>\n<ul>\n<li>FAP\u306e\u5bb6\u7cfb\u3067\uff0c\u5c0f\u5150\u306b\u80ce\u5150\u6027\u8133\u816b\u760d\uff08\u9ac4\u82bd\u816b\uff09\u3092\u751f\u3058\u307e\u3059<\/li>\n<\/ul>\n<h4>\u30ac\u30fc\u30c9\u30ca\u30fc\u75c7\u5019\u7fa4 Gardner&#8217;s syndrome<\/h4>\n<ul>\n<li>FAP\u306b\u982d\u84cb\u9aa8\u816b\u760d\u306a\u3069\u3092\u5408\u4f75\u3059\u308b\u3082\u306e\u3067\u3059<\/li>\n<\/ul>\n<h4 align=\"left\">\u30ea\u30fb\u30d5\u30e9\u30a6\u30e1\u30cb\u75c7\u5019\u7fa4 Li\u2013Fraumeni syndrom<\/h4>\n<ul>\n<li>TP53\u764c\u6291\u5236\u907a\u4f1d\u5b50\u306b\u5909\u7570\u304c\u3042\u308a\u307e\u3059<\/li>\n<li>\u5c0f\u5150\u8133\u816b\u760d\uff0c\u30b0\u30ea\u30aa\u30fc\u30de\u3092\u767a\u751f\u3059\u308b\u907a\u4f1d\u6027\u75be\u60a3\u3067\u3059<\/li>\n<li>\u4ed6\u306b\u306f\uff0c\u5927\u8178\u304c\u3093\uff0c\u4e73\u304c\u3093\uff0c\u8089\u816b\u3092\u767a\u751f\u3057\u307e\u3059<\/li>\n<\/ul>\n<h4 align=\"left\">\u30b4\u30fc\u30ea\u30f3\u75c7\u5019\u7fa4 Gorlin syndrome<\/h4>\n<ul>\n<li>\u9ac4\u82bd\u816b\u304c\u9ad8\u7387\u306b\u767a\u751f\u3057\u307e\u3059<\/li>\n<li>\u6bcd\u6591\u6027\u57fa\u5e95\u7d30\u80de\u304c\u3093\u75c7\u5019\u7fa4\u3068\u3044\u3044\u307e\u3059<\/li>\n<li>\u76ae\u819a\u304c\u3093\uff0c\u7279\u306b\u57fa\u5e95\u7d30\u80de\u764c\u3092\u767a\u751f\u3059\u308b\u3082\u306e\u3067\u3059<\/li>\n<li>\u653e\u5c04\u7dda\u6cbb\u7642\u3092\u3059\u308b\u3068\u9ad8\u7387\u306b\u76ae\u819a\u304c\u3093\u304c\u751f\u3058\u307e\u3059<\/li>\n<\/ul>\n<h4>\u30ea\u30f3\u30c1\u75c7\u5019\u7fa4 Lynch syndrome<\/h4>\n<ul>\n<li>\u30ea\u30f3\u30c1\u75c7\u5019\u7fa4\u306e10-20%\u306b\uff0c\u81a0\u82bd\u816b\uff0c\u3073\u307e\u3093\u6027\u661f\u7d30\u80de\u816b\uff0c\u4e4f\u7a81\u8d77\u81a0\u816b\u304c\u767a\u751f\u3057\u307e\u3059<\/li>\n<li>\u30df\u30b9\u30de\u30c3\u30c1\u4fee\u5fa9\u907a\u4f1d\u5b50\u306e\u5909\u7570\u304c\u539f\u56e0\u3068\u3055\u308c\uff0c\u5927\u8178\u30ac\u30f3\u306a\u3069\u304c\u591a\u767a\u3057\u307e\u3059<\/li>\n<li>MMR\u907a\u4f1d\u5b50\u5909\u7570\u304c\u3042\u308b\u3068\u5c0f\u5150\u671f\u306b\u30b0\u30ea\u30aa\u30fc\u30de\u304c\u767a\u751f\u3059\u308b\u50be\u5411\u306b\u3042\u308a\u307e\u3059<\/li>\n<\/ul>\n<hr \/>\n<h1 align=\"left\">\u65b0\u751f\u5150\u306e\u5148\u5929\u6027\u8133\u816b\u760d<\/h1>\n<h4 align=\"left\">\u5b9a\u7fa9<\/h4>\n<ul>\n<li>\u53b3\u5bc6\u306b\uff0c\u5148\u5929\u6027\u8133\u816b\u760d\u306f\uff0c\u80ce\u5150\u671f\u3068\u65b0\u751f\u5150\u671f\uff08<span style=\"color: #ff0000;\"><strong>\u751f\u5f8c\uff14\u9031\u9593\u4ee5\u5185<\/strong><\/span>\uff09\u306b\u8a3a\u65ad\u3055\u308c\u305f\u816b\u760d\u3067\u3059<\/li>\n<li>1951\u5e74Arnstein LH\u306f\uff0c\u51fa\u751f\u5f8c60\u65e5\u4ee5\u5185\u306b\u75c7\u5019\u3092\u5448\u3059\u308b\u8133\u816b\u760d\u3092\uff0c\u5148\u5929\u6027\u8133\u816b\u760d\u3068\u3057\u3066\u521d\u3081\u3066\u8a18\u8f09\u3057\u307e\u3057\u305f<\/li>\n<li>1964\u5e74Solitare GB\u304c\uff0c\u5148\u5929\u6027\u8133\u816b\u760d\u306e\u75c7\u5019\u3092\u8a8d\u3081\u308b\u6642\u671f\u306b\u3088\u308a\uff0c\u751f\u4e0b\u6642\u306b\u8a8d\u3081\u308b\u3082\u306e\uff08definitely congenital\uff09\uff0c\u751f\u5f8c1\u9031\u9593\u4ee5\u5185\u306b\u8a8d\u3081\u308b\u3082\u306e\uff08probably congenital\uff09\uff0c\u751f\u5f8c1\u30f6\u6708\u4ee5\u5185\u306b\u8a8d\u3081\u3089\u308c\u308b\u3082\u306e\uff08possibly congenital\uff09\u306e3\u3064\u306e\u533a\u5206\u3092\u63d0\u5531\u3057\u307e\u3057\u305f<\/li>\n<li>\u80ce\u751f\u671f\u306b\u8a3a\u65ad\u3055\u308c\u308b\u3082\u306e\u306f\uff0c\u771f\u306edefinitely congenital brain tumor\u3067\u3059<\/li>\n<\/ul>\n<h4 align=\"left\"><strong>\u767a\u751f\u983b\u5ea6<\/strong><\/h4>\n<p align=\"left\">\u751f\u5f8c1\u5e74\u4ee5\u5185\u306b\u8a3a\u65ad\u3055\u308c\u308b\u8133\u816b\u760d\u306f\uff0c\u5168\u5c0f\u5150\u8133\u816b\u760d\u306e13.9\uff05\u3068\u3044\u308f\u308c\uff0c\u3053\u306e\u3046\u3061\u5148\u5929\u6027\u8133\u816b\u760d\u3068\u8a3a\u65ad\u3055\u308c\u308b\u3082\u306e\u306f0.5-1.5\uff05\u3067\uff0c\u51fa\u751f100\u4e07\u306b\u5bfe\u30570.34\u3068\u3055\u308c\u307e\u3059\u3002\u80ce\u5150\u671f\u306b\u8a3a\u65ad\u3055\u308c\u308b\u8133\u816b\u760d\u306b\u3044\u305f\u3063\u3066\u306f\uff0c\u3053\u308c\u3088\u308a\u66f4\u306b\u983b\u5ea6\u304c\u4f4e\u3044\u3067\u3059\u3002\u8133\u816b\u760d\u306e\u305f\u3081\u6b7b\u4ea1\u3059\u308b\u80ce\u5150\u4f8b\u304c\u3042\u308b\u3053\u3068\u3082\u65b0\u751f\u5150\u8133\u816b\u760d\u306e\u983b\u5ea6\u304c\u4f4e\u3044\u7406\u7531\u3068\u306a\u3063\u3066\u3044\u308b\u306e\u3067\u3057\u3087\u3046\u3002<\/p>\n<h4 align=\"left\"><strong>\u7a2e\u985e<\/strong><\/h4>\n<p align=\"left\">\u6ce8\u610f\u3057\u305f\u3044\u306e\u306f\uff0c\u7d44\u7e54\u578b\u304c\u5b9f\u306b\u69d8\u3005\u306a\u3053\u3068\u3067\u3059\u3002\u6642\u3068\u3057\u3066\u306f\uff0c\u75c5\u7406\u8a3a\u65ad\u540d\u3092\u3064\u3051\u308b\u3053\u3068\u304c\u3067\u304d\u306a\u3044\u3088\u3046\u306a\u6975\u3081\u3066\u5de8\u5927\u306a\u904e\u8aa4\u816b\uff0c\u6587\u732e\u4e0a\u3067\u3082\u306a\u3044\u3088\u3046\u306a\u975e\u5f97\u610f\u7684\u306a\u75c5\u7406\u50cf\u3092\u5448\u3059\u308b\u60aa\u6027\u816b\u760d\u3082\u3042\u308a\u307e\u3059\u304c\uff0c\u3053\u308c\u3089\u306e\u4e88\u5f8c\u306f\u4e0d\u826f\u3067\u3059\u3002<\/p>\n<p align=\"left\">\u5148\u5929\u6027\u8133\u816b\u760d\u306e\u591a\u6570\u4f8b\u3092\u691c\u8a0e\u3057\u305f\u5831\u544a\u3067\u306f\uff0c<span style=\"color: #ff0000;\"><strong>\u5947\u5f62\u816b\u304c\u3082\u3063\u3068\u3082\u591a\u3044<\/strong><\/span>\u3067\u3059\u3002\u6b21\u3044\u3067\u661f\u7d30\u80de\u816b\uff0c\u8108\u7d61\u53e2\u4e73\u982d\u816b\uff0c\u81a0\u82bd\u816b\uff0c\u672a\u5206\u5316\u795e\u7d4c\u5916\u80da\u8449\u6027\u816b\u760d\uff08PNET\uff09\u30fb\u9ac4\u82bd\u816b\uff0c\u4e0a\u8863\u816b\u306a\u3069\u304c\u6319\u3052\u3089\u308c\u307e\u3059\u3002\u4e0a\u8a18\u4ee5\u5916\u306b\u306f\uff0c\u81a0\u8089\u816b (gliosarcoma)\uff0c\u9ac4\u819c\u816b\uff0c\u30b8\u30e3\u30fc\u30df\u30ce\u30fc\u30de\uff0c\u6bdb\u69d8\u7d30\u80de\u6027\u661f\u7d30\u80de\u816b\uff0c\u982d\u84cb\u54bd\u982d\u816b\uff0catypical teratoid\/rhabdoid tumor (AT\/RT )\uff0c\u60aa\u6027\u80da\u7d30\u80de\u816b\u760d\uff0c\u7dda\u7dad\u5f62\u6210\u6027\u4e73\u5150\u661f\u7d30\u80de\u816b\u30fb\u795e\u7d4c\u7bc0\u81a0\u816b (desmoplastic infantile astrocytoma \/ gangliogalioma)\u306a\u3069\u306e\u75c7\u4f8b\u5831\u544a\u304c\u6563\u898b\u3055\u308c\u307e\u3059\u3002\u307e\u305f\u7d50\u7bc0\u6027\u786c\u5316\u75c7\u306b\u5408\u4f75\u3059\u308b\u8133\u5ba4\u4e0a\u8863\u4e0b\u5de8\u7d30\u80de\u6027\u661f\u72b6\u7d30\u80de\u816b\u306e\u5831\u544a\u3082\u3042\u308a\u307e\u3059\u3002\u5148\u5929\u6027\u306e\u5947\u5f62\u816b\u306f\uff0c\u5e74\u9577\u5150\u306b\u898b\u3089\u308c\u308b\u80da\u7d30\u80de\u816b\u760d\u3068\u3057\u3066\u306e\u5947\u5f62\u816b\u3068\u306f\u767a\u751f\u539f\u56e0\u304c\u7570\u306a\u308b\u816b\u760d\u3067\u3042\u308a\u4e00\u7dda\u3092\u753b\u3059\u3079\u304d\u75be\u60a3\u3067\u3059\u3002<\/p>\n<p align=\"left\">\u5897\u6b96\u6027\u816b\u760d\u3068\u3057\u3066\u306e\u6027\u683c\u3092\u6301\u305f\u306a\u3044\u5148\u5929\u6027\u816b\u760d\u3067\u3042\u308b\u80da\u82bd\u7570\u5f62\u6210\u6027\u795e\u7d4c\u4e0a\u76ae\u816b\u760d (DNT, dysembryoplastic neuroectodermal tumor)\uff0c\u8996\u5e8a\u4e0b\u90e8\u904e\u8aa4\u816b (hypothalamic hamartoma) \u306a\u3069\u306e\u904e\u8aa4\u816b\u7684\u306a\u3082\u306e\u3084\u76ae\u8cea\u7570\u5f62\u6210 (cortical dysplasia) \u306b\u985e\u4f3c\u3059\u308b\u3082\u306e\u304c\u3042\u308a\uff0c\u3053\u308c\u3089\u306f\u539f\u5247\u3068\u3057\u3066\u6cbb\u7642\u3092\u5fc5\u8981\u3068\u3057\u307e\u305b\u3093\u3002<\/p>\n<h4 align=\"left\"><strong>\u90e8\u4f4d<\/strong><\/h4>\n<p align=\"left\">\u307b\u3068\u3093\u3069\u306e\u65b0\u751f\u5150\u671f\u8133\u816b\u760d\u306f\u305d\u306e\u816b\u760d\u672c\u6765\u306e\u597d\u767a\u90e8\u4f4d\u306b\u767a\u751f\u3057\u307e\u3059\u3002\u661f\u7d30\u80de\u816b\u30fb\u81a0\u82bd\u816b\u30fbPNET\u3067\u3042\u308c\u3070\u5927\u8133\uff0c\u9ac4\u82bd\u816b\u30fb\u4e0a\u8863\u816b\u306f\u7b2c4\u8133\u5ba4\u3042\u308b\u3044\u306f\u5c0f\u8133\uff0c\u8108\u7d61\u53e2\u4e73\u982d\u816b\u306f\u5074\u8133\u5ba4\u3042\u308b\u3044\u306f\u7b2c\uff13\u8133\u5ba4\u306b\u591a\u304f\uff0c\u8996\u5e8a\u4e0b\u90e8\u904e\u8aa4\u816b\u3067\u3042\u308c\u3070\u978d\u4e0a\u90e8\u304b\u3089\u7b2c\uff13\u8133\u5ba4\u5e95\u90e8\u3067\u3059\u3002\u5f93\u3063\u3066\u3053\u308c\u3089\u306f\u4ed6\u306e\u5e74\u9f62\u5c64\u306e\u5c0f\u5150\u3068\u540c\u69d8\u3067\u3059\u3002\u3057\u304b\u3057\uff0c\u5e74\u9577\u5150\u306e\u5947\u5f62\u816b\u304c\u677e\u679c\u4f53\u3042\u308b\u3044\u306f\u9593\u8133\u4e0b\u5782\u4f53\u306b\u591a\u3044\u306e\u306b\u53cd\u3057\u3066\uff0c\u65b0\u751f\u5150\u671f\u306e\u5947\u5f62\u816b\u306f\u982d\u84cb\u5185\u306e\u3069\u3053\u306e\u90e8\u4f4d\u306b\u767a\u751f\u3057\u3066\u8133\u5ba4\u5185\u3084\u982d\u84cb\u5e95\u306b\u3082\u307f\u3089\u308c\u307e\u3059\u3002<\/p>\n<h4 align=\"left\"><strong>\u75c7\u5019\u3068\u8a3a\u65ad<\/strong><\/h4>\n<p align=\"left\">\u5148\u5929\u6027\u8133\u816b\u760d\u306b\u306f<strong><span style=\"color: #ff0000;\">\u982d\u84cb\u5185\u51fa\u8840<\/span><\/strong>\u304c14\u301c18\uff05\u306b\u5408\u4f75\u3059\u308b\u3068\u306e\u5831\u544a\u304c\u3042\u308a\u307e\u3059\u3002\u3053\u306e\u983b\u5ea6\u306f\u5168\u5c0f\u5150\u8133\u816b\u760d\u3067\u307f\u3089\u308c\u308b\u816b\u760d\u51fa\u8840\u5408\u4f75\u7387\u3068\u6bd4\u3057\u3066\u9ad8\u3044\u3067\u3059\u3002\u3055\u3089\u306b\uff0c\u5148\u5929\u6027\u8133\u816b\u760d\u306e\u60a3\u5150\u306e15\uff05\u306b\u5408\u4f75\u5947\u5f62\u304c\u8a8d\u3081\u3089\u308c\uff0c\u7279\u306b\u5947\u5f62\u816b\u306e\u75c7\u4f8b\u306b\u983b\u5ea6\u304c\u9ad8\u3044\u3067\u3059\u3002\u307e\u308c\u306a\u75be\u60a3\u3067\u3059\u304c\u80ce\u5150\u306e\u8133\u816b\u760d\u306f\u6c34\u982d\u75c7\u3084\u982d\u84cb\u5185\u51fa\u8840\u3092\u5408\u4f75\u3057\u3084\u3059\u3044\u3067\u3059\u3002\u80ce\u5150\u6c34\u982d\u75c7\u3084\u982d\u84cb\u5185\u51fa\u8840\u306e\u539f\u56e0\u306f\u816b\u760d\u4ee5\u5916\u306e\u75be\u60a3\u306b\u8d77\u56e0\u3059\u308b\u3053\u3068\u304c\u5727\u5012\u7684\u306b\u591a\u3044\u306e\u3067\uff0c\u8133\u816b\u760d\u306e\u5b58\u5728\u304c\u898b\u9003\u3055\u308c\u3066\u8aa4\u8a3a\u3068\u306a\u308b\u75c7\u4f8b\u3082\u3042\u308b\u3053\u3068\u306f\u3057\u304b\u305f\u304c\u3042\u308a\u307e\u305b\u3093\u3002<\/p>\n<p align=\"left\"><a href=\"\/sawamura\/wp\/wp-content\/uploads\/2014\/07\/newbornchoroidp1.jpg\"><img loading=\"lazy\" decoding=\"async\" class=\"alignleft size-thumbnail wp-image-6105\" title=\"newbornchoroidp1\" src=\"\/sawamura\/wp\/wp-content\/uploads\/2014\/07\/newbornchoroidp1-200x200.jpg\" alt=\"\" width=\"200\" height=\"200\" srcset=\"https:\/\/plaza.umin.ac.jp\/sawamura\/wp\/wp-content\/uploads\/2014\/07\/newbornchoroidp1-200x200.jpg 200w, https:\/\/plaza.umin.ac.jp\/sawamura\/wp\/wp-content\/uploads\/2014\/07\/newbornchoroidp1-298x300.jpg 298w, https:\/\/plaza.umin.ac.jp\/sawamura\/wp\/wp-content\/uploads\/2014\/07\/newbornchoroidp1-550x552.jpg 550w, https:\/\/plaza.umin.ac.jp\/sawamura\/wp\/wp-content\/uploads\/2014\/07\/newbornchoroidp1.jpg 1181w\" sizes=\"auto, (max-width: 200px) 100vw, 200px\" \/><\/a><a href=\"\/sawamura\/wp\/wp-content\/uploads\/2014\/07\/newbornchoroidp2.jpg\"><img loading=\"lazy\" decoding=\"async\" class=\"alignleft size-thumbnail wp-image-6106\" title=\"newbornchoroidp2\" src=\"\/sawamura\/wp\/wp-content\/uploads\/2014\/07\/newbornchoroidp2-200x200.jpg\" alt=\"\" width=\"200\" height=\"200\" \/><\/a><\/p>\n<p align=\"left\">\u80ce\u515034\u9031\u306e\u53f3\u5074\u8133\u5ba4\u306b\u751f\u3058\u305f\u8133\u5ba4\u5185\u51fa\u8840\u3068\u982d\u56f2\u62e1\u5927\u3092\u6bcd\u4f53\u5185\u306eMRI\u3067\u8a3a\u65ad\u3057\u305f\u3082\u306e\u3067\u3059\u3002\u8840\u816b\u306e\u4e2d\u5fc3\u90e8\u306b\u826f\u6027\u306e\u8108\u7d61\u53e2\u4e73\u982d\u816b\u304c\u8a8d\u3081\u3089\u308c\u307e\u3059\uff08\u77e2\u5370\uff09\u3002\u5b50\u5bae\u5185\u3067\u306e\u9ad8\u5ea6\u306e\u982d\u84cb\u5185\u5727\u4ea2\u9032\u304c\u4e88\u60f3\u3055\u308c\u305f\u305f\u3081\uff0c35\u9031\u76ee\u306b\u5e1d\u738b\u5207\u958b\u3092\u884c\u3044\u307e\u3057\u305f\u3002\u51fa\u751f\u540c\u65e5\u8133\u5ba4\u30c9\u30ec\u30ca\u30fc\u30b8\u3067\u8133\u5727\u3092\u30b3\u30f3\u30c8\u30ed\u30fc\u30eb\u3057\uff0c\u751f\u5f8c24\u65e5\u76ee\u306b\u53f3\u524d\u982d\u958b\u982d\u306b\u3088\u308b\u8840\u816b\u9664\u53bb\u3068\u816b\u760d\u5168\u6458\u51fa\u3055\u3089\u306b\u8133\u5ba4\u8179\u8154\u30b7\u30e3\u30f3\u30c8\u8853\u3092\u3057\u307e\u3057\u305f\u3002\u3053\u306e\u4f8b\u3067\u306f\u8a3a\u65ad\u5f8c\u306b\u6cbb\u7642\u3092\u6025\u3044\u3060\u306e\u3067\u3059\u304c\uff0c\u80ce\u751f\u671f\u306e\u982d\u84cb\u5185\u5727\u4ea2\u9032\u306b\u3088\u308b\u4e21\u5074\u8996\u795e\u7d4c\u840e\u7e2e\u3068\u9ad8\u5ea6\u306e\u8996\u529b\u969c\u5bb3\u3092\u6b8b\u3057\u307e\u3057\u305f\u3002<\/p>\n<p align=\"left\">\u51fa\u751f\u5f8c\u306b\u8a8d\u3081\u3089\u308c\u308b\u5148\u5929\u6027\u8133\u816b\u760d\u306e\u4e3b\u8981\u306a\u75c7\u5019\u306f\uff0c\u6c34\u982d\u75c7\u306b\u4f34\u3046\u982d\u56f2\u62e1\u5927\u30fb\u6cc9\u9580\u306e\u81a8\u9686\u3067\u3042\u308a\u534a\u6570\u4ee5\u4e0a\u306e\u75c7\u4f8b\u3067\u8a8d\u3081\u3089\u308c\uff0c\u3068\u308a\u308f\u3051\u51fa\u751f\u76f4\u5f8c\u306b\u8a3a\u65ad\u3055\u308c\u308b\u5148\u5929\u6027\u8133\u816b\u760d\u3067\u306f\uff0c\u982d\u56f2\u62e1\u5927\u304c\u6700\u3082\u591a\u304f\u8a8d\u3081\u3089\u308c\u308b\u75c7\u5019\u3067\u3059\u3002\u65b0\u751f\u5150\u671f\u306e\u8133\u816b\u760d\u306e\u75c7\u5019\u306e\u7279\u5fb4\u3068\u3057\u3066\uff0c\u982d\u84cb\u9aa8\u306e\u9aa8\u7652\u5408\u304c\u5b8c\u6210\u3057\u3066\u3044\u306a\u3044\u305f\u3081\u982d\u56f2\u62e1\u5927\u306f\u9032\u884c\u3057\u3066\u3082\u5614\u5410\u306a\u3069\u306e\u982d\u84cb\u5185\u5727\u4ea2\u9032\u75c7\u72b6\u306f\u6bd4\u8f03\u7684\u73fe\u308f\u308c\u306b\u304f\u3044\u3053\u3068\u304c\u6307\u6458\u3055\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n<p align=\"left\">\u65b0\u751f\u5150\u306e\u8133\u816b\u760d\u3092\u7591\u3046\u6642\u306b\u306fMRI\u884c\u3044\u307e\u3059\u304c\uff0c\u5b9f\u306b\u591a\u5f69\u306a\u816b\u760d\u304c\u767a\u751f\u3057\u305d\u306e\u6240\u898b\u3082\u69d8\u3005\u3067\u8a3a\u65ad\u306f\u96e3\u3057\u3044\u3082\u306e\u3067\u3059\u3002\u767a\u751f\u90e8\u4f4d\u3084\u7279\u5fb4\u7684\u306a\u753b\u50cf\u6240\u898b\u304b\u3089\u8a3a\u65ad\u304c\u6bd4\u8f03\u7684\u5bb9\u6613\u3067\u304b\u3064\u983b\u5ea6\u304c\u9ad8\u3044\u3082\u306e\u306b\u306f\u5947\u5f62\u816b\uff0c\u8108\u7d61\u53e2\u4e73\u982d\u816b\uff0c\u8996\u5e8a\u4e0b\u90e8\u904e\u8aa4\u816b\u3067\u3059\u3002\u5947\u5f62\u816b\u3068\u8108\u7d61\u53e2\u4e73\u982d\u816b\u306e\u60aa\u6027\u5ea6\u306b\u95a2\u3057\u3066\u306e\u753b\u50cf\u8a3a\u65ad\u306f\u4e8b\u5b9f\u4e0a\u306f\u4e0d\u53ef\u80fd\u3068\u3044\u3048\u307e\u3059\u3002<\/p>\n<h4 align=\"left\"><strong>\u6cbb\u7642\u65b9\u6cd5<\/strong><\/h4>\n<p align=\"left\">\u80ce\u5150\u671f\u306e\u8133\u816b\u760d\u3067\u306f\u4ed6\u306e\u5c0f\u5150\u8133\u816b\u760d\u3068\u6bd4\u8f03\u3057\u3066\uff0c\u816b\u760d\u304c\u5de8\u5927\u3068\u306a\u308a\u6b63\u5e38\u306a\u8133\u7d44\u7e54\u3092\u5927\u304d\u304f\u5727\u6392\u3057\u7f6e\u63db\u3057\u3066\u3044\u308b\u72b6\u614b\u3067\u8a3a\u65ad\u3055\u308c\u307e\u3059\u3002\u5f93\u3063\u3066\uff0c\u51fa\u751f\u76f4\u5f8c\u304b\u3089\u65b0\u751f\u5150\u671f\u306b\u6cbb\u7642\u3092\u5b9f\u65bd\u3059\u308b\u4ee5\u524d\u306b\u6b7b\u306b\u81f3\u308b\u5272\u5408\u3082\u9ad8\u3044\u3082\u306e\u3067\u3059\u3002\u7279\u306b\u80ce\u5150\u671f\u306b\u8a3a\u65ad\u3055\u308c\u305f\u8133\u816b\u760d\u306e\u751f\u547d\u4e88\u5f8c\u3068\u751f\u5b58\u5f8c\u306e\u6a5f\u80fd\u4e88\u5f8c\u306f\u4e00\u822c\u7684\u306b\u306f\u4e0d\u826f\u3067\u3059\u3002\u3053\u306e\u3088\u3046\u306a\u4e88\u5f8c\u3092\u9451\u307f\u305f\u4e0a\u3067\uff0c<span style=\"color: #ff0000;\"><strong>\u7a4d\u6975\u7684\u6cbb\u7642\u3092\u884c\u3046\u3079\u304d\u304b\u3069\u3046\u304b\u306f\uff0c\u4e00\u822c\u7684\u306b\u306f\u6982\u8aac\u3067\u304d\u305a\uff0c\u500b\u3005\u306e\u75c7\u4f8b\u306b\u304a\u3044\u3066\u975e\u5e38\u306b\u614e\u91cd\u3067\u56f0\u96e3\u306a\u5224\u65ad<\/strong><\/span>\u3068\u306a\u3089\u3056\u308b\u3092\u5f97\u307e\u305b\u3093\u3002<\/p>\n<p align=\"left\">\u65b0\u751f\u5150\u671f\u306e\u8133\u816b\u760d\u306e\u57fa\u672c\u6cbb\u7642\u65b9\u91dd\u306f\uff0c\u5916\u79d1\u6cbb\u7642\u3067\u3059\u3002\u6c34\u982d\u75c7\u306b\u5bfe\u3059\u308b\u77ed\u7d61\u8853\u306f\u5fc5\u8981\u306b\u5fdc\u3058\u3066\u884c\u3044\u307e\u3059\u3002\u3055\u3089\u306b\u65b0\u751f\u5150\u671f\u3092\u904e\u304e\u3066\u4e73\u5150\u671f\u306b\u306a\u308c\u3070\uff0c\u816b\u760d\u306e\u75c5\u7406\u7d44\u7e54\u306b\u3088\u308a\u5316\u5b66\u7642\u6cd5\u304c\u52a0\u3048\u3089\u308c\u3066\u3044\u308b\u3053\u3068\u3082\u3042\u308a\u307e\u3059\u3002\u65b0\u751f\u5150\u306e\u4e2d\u67a2\u795e\u7d4c\u7d44\u7e54\u306f\u672a\u719f\u306a\u305f\u3081\u306b\u653e\u5c04\u7dda\u6cbb\u7642\u3092\u884c\u3046\u3053\u3068\u306f\u3067\u304d\u307e\u305b\u3093\u3002\u5e74\u4f59\u306e\u9577\u671f\u751f\u5b58\u304c\u5f97\u3089\u308c\u3066\u304b\u3064\u816b\u760d\u304c\u6b8b\u5b58\u3057\u305f\u75c7\u4f8b\u306b\u304a\u3044\u3066\u306e\u307f\uff0c\u60a3\u5150\u306e\u6210\u9577\u3092\u5f85\u3063\u3066\u304b\u3089\u88dc\u52a9\u7642\u6cd5\u3068\u3057\u3066\u306e\u653e\u5c04\u7dda\u6cbb\u7642\u304c\u8003\u616e\u306b\u5165\u308a\u307e\u3059\u3002\u5f93\u3063\u3066\uff0c\u5916\u79d1\u6458\u51fa\u3067\u816b\u760d\u304c\u30b3\u30f3\u30c8\u30ed\u30fc\u30eb\u3067\u304d\u306a\u3044\u65b0\u751f\u5150\u671f\u306e\u8133\u816b\u760d\u306e\u5834\u5408\u306b\u306f\u751f\u547d\u4e88\u5f8c\u306f\u7d76\u5bfe\u7684\u306b\u4e0d\u826f\u3067\u3059\u3002<\/p>\n<p align=\"left\">\u624b\u8853\u306e\u6642\u671f\u306b\u95a2\u3057\u3066\u306f\uff0c\u753b\u50cf\u8a3a\u65ad\u304b\u3089\u4e88\u60f3\u3055\u308c\u308b\u816b\u760d\u306e\u60aa\u6027\u5ea6\u306b\u3088\u3063\u3066\u7570\u306a\u308b\u306e\u3067\u4e00\u6982\u306b\u306f\u6c7a\u3081\u308b\u3053\u3068\u304c\u3067\u304d\u307e\u305b\u3093\u304c\uff0c\u826f\u6027\u816b\u760d\u306f\u3067\u304d\u308b\u9650\u308a\u5f85\u6a5f\u624b\u8853\u3068\u3057\u307e\u3059\u3002\u3057\u304b\u3057\uff0c\u65b0\u751f\u5150\u671f\u306e\u816b\u760d\u306f\u6613\u51fa\u8840\u6027\u3067\uff0c\u305d\u306e\u305f\u3081\u306e\u624b\u8853\u6b7b\u3082\u3042\u308a\u3046\u308b\u96e3\u6613\u5ea6\u306e\u9ad8\u3044\u624b\u8853\u3067\u3059\u3002\u307e\u305f\uff0c\u56a2\u80de\u3092\u4f34\u3046\u5de8\u5927\u306a\u826f\u6027\u816b\u760d\u3067\u306f\u56a2\u80de\u306e\u7a7f\u523a\u3042\u308b\u3044\u306f\u90e8\u5206\u6458\u51fa\u306b\u3068\u3069\u3081\u3066\uff0c\u8133\u306e\u5727\u6392\u3092\u89e3\u9664\u3057\u3066\u304b\u3089\u3042\u308b\u3044\u306f\u60a3\u5150\u306e\u6210\u9577\u3092\u5f85\u3063\u3066\u304b\u3089\uff12\u671f\u7684\u306b\u5168\u6458\u51fa\u3059\u308b\u3053\u3068\u3082\u8003\u616e\u3057\u307e\u3059\u3002<\/p>\n<p align=\"left\">\u3082\u3061\u308d\u3093\u4e0d\u8981\u306a\u6cbb\u7642\u3092\u884c\u3063\u3066\u306f\u306a\u3089\u306a\u3044\u306e\u3067\u624b\u8853\u306b\u3088\u308b\u751f\u691c\u8853\u3092\u884c\u3046\u304b\u3069\u3046\u304b\u306e\u5224\u65ad\u306f\u304b\u306a\u308a\u306e\u5c02\u9580\u7684\u306a\u77e5\u8b58\u3092\u8981\u3057\u307e\u3059\u3002\u65e9\u671f\u306e\u624b\u8853\u3092\u3042\u3048\u3066\u907f\u3051\u306a\u3051\u308c\u3070\u306a\u3089\u306a\u3044\u3082\u306e\u306b\u8996\u5e8a\u4e0b\u90e8\u904e\u8aa4\u816b\uff0c\u8996\u4ea4\u53c9\u306e\u6bdb\u69d8\u7d30\u80de\u6027\u661f\u7d30\u80de\u816b\uff0c\u76ae\u8cea\u5f62\u6210\u7570\u5e38\uff0cDNT\u306a\u3069\u304c\u3042\u3052\u3089\u308c\u307e\u3059\u3002<\/p>\n<h4 align=\"left\"><strong>\u624b\u8853\u624b\u6280\u306e\u9078\u629e\u3068\u7279\u6b8a\u6027<\/strong><\/h4>\n<p align=\"left\">\u65b0\u751f\u5150\u3068\u4e73\u5150\u671f\u306e\u8133\u816b\u760d\u6458\u51fa\u8853\u306e\u96e3\u3057\u3055\u306f\uff0c\u9ac4\u9798\u306e\u767a\u9054\u304c\u4e0d\u5b8c\u5168\u3067\u8edf\u819c\u304c\u8584\u3044\u306a\u3069\u8133\u7d44\u7e54\u304c\u6975\u3081\u3066\u8106\u5f31\u3067\uff0c\u8133\u3079\u3089\u306a\u3069\u306e\u5727\u6392\u306b\u3088\u3063\u3066\u8133\u7d44\u7e54\u304c\u5bb9\u6613\u306b\u5d29\u308c\u3066\u3057\u307e\u3046\u3068\u3044\u3046\u3053\u3068\u306b\u3042\u308a\u307e\u3059\u3002\u540c\u6642\u306b\u53ef\u5851\u6027\u304c\u306a\u304f\u8133\u3092\u5909\u5f62\u3055\u305b\u3066\u3088\u3051\u308b\u3053\u3068\u304c\u96e3\u3057\u3044\u3067\u3059\u3002\u6c34\u982d\u75c7\u306e\u7121\u3044\u4f8b\u3067\u306f\u30b7\u30eb\u30d3\u30a6\u30b9\u88c2\u3092\u958b\u3051\u3066\u978d\u4e0a\u90e8\u306b\u5165\u308b\u306a\u3069\u5b9f\u969b\u306b\u306f\u3067\u304d\u307e\u305b\u3093\u3002<\/p>\n<p align=\"left\">\u6700\u3082\u591a\u3044\u5947\u5f62\u816b\u3067\u306f\uff0c\u5897\u5927\u901f\u5ea6\u304c\u7de9\u5f90\u306a\u6210\u719f\u5947\u5f62\u816b\u304c\u591a\u3044\u306e\u3067\u624b\u8853\u3092\u6025\u3050\u5fc5\u8981\u6027\u306f\u306a\u3044\u306e\u3067\uff0c\u3067\u304d\u308b\u9650\u308a\u5f85\u6a5f\u624b\u8853\u3068\u3057\u307e\u3059\u3002\u5de8\u5927\u306a\u5947\u5f62\u816b\u3067\u306f\u51fa\u8840\u91cf\u306b\u5fdc\u3058\u3066\u624b\u8853\u3092\uff12\u671f\u7684\u306b\u5206\u3051\u308b\u3053\u3068\u304c\u3088\u3044\u3057\uff0c\u3053\u306e\u816b\u760d\u3067\u306f\u6b62\u8840\u306b\u96e3\u6e0b\u3059\u308b\u3053\u3068\u306f\u306a\u3044\u3067\u3057\u3087\u3046\u3002\u826f\u6027\u5947\u5f62\u816b\u306e\u5834\u5408\uff0c\u7b2c\uff11\u56de\u76ee\u306e\u624b\u8853\u3067\u306f\u8133\u3078\u306e\u5727\u8feb\u3092\u89e3\u9664\u3059\u308b\u3053\u3068\u3092\u76ee\u7684\u3057\u307e\u3059\u3002\u307e\u305f\u90e8\u5206\u6458\u51fa\u5f8c\u306b\u591a\u5c11\u306e\u6b8b\u5b58\u816b\u760d\u304c\u3042\u3063\u3066\u3082\u305d\u308c\u304c\u5168\u304f\u5897\u5927\u3057\u3066\u3053\u306a\u3044\u3053\u3068\u3082\u3042\u308b\u306e\u3067\uff0c\u7121\u7406\u306a\u5168\u6458\u51fa\u306f\u3057\u307e\u305b\u3093\u3002<\/p>\n<p align=\"left\">\u8108\u7d61\u53e2\u4e73\u982d\u816b\u3068\u8108\u7d61\u53e2\u4e73\u982d\u764c\u306f\uff0c\u7279\u306b\u624b\u8853\u4e2d\u306e\u51fa\u8840\u91cf\u304c\u591a\u3044\u306e\u3067\u5f85\u6a5f\u624b\u8853\u3068\u3057\u3066\u4f53\u91cd\u306e\u5897\u52a0\u3092\u5f85\u3061\u307e\u3059\u3002\u591a\u91cf\u306e\u9ac4\u6db2\u7523\u751f\u80fd\u3092\u6709\u3059\u308b\u8108\u7d61\u53e2\u4e73\u982d\u816b\u306b\u5bfe\u3057\u3066\uff0c\u65b0\u751f\u5150\u3067\u306f\u8179\u90e8\u3067\u306e\u9ac4\u6db2\u5438\u53ce\u80fd\u304c\u5341\u5206\u3067\u306f\u306a\u3044\u306e\u3067\u8133\u5ba4\u8179\u8154\u77ed\u7d61\u8853\u3092\u884c\u3046\u3053\u3068\u306f\u3067\u304d\u307e\u305b\u3093\u3002\u816b\u760d\u6458\u51fa\u524d\u306b\u8133\u5ba4\u30c9\u30ec\u30ca\u30fc\u30b8\u3092\u3057\u306a\u304c\u3089\u5f85\u6a5f\u624b\u8853\u3068\u3057\u307e\u3059\u3002\u8133\u5ba4\u5185\u816b\u760d\u3067\u3042\u308b\u306e\u3067\u7d30\u3044\u8108\u7d61\u53e2\u52d5\u8108\u3092\u9078\u629e\u7684\u306b\u8a70\u3081\u308b\u816b\u760d\u52d5\u8108\u585e\u6813\u8853\u306f\u73fe\u5b9f\u7684\u3067\u306f\u3042\u308a\u307e\u305b\u3093\u3002\u7b2c\uff13\u8133\u5ba4\u306e\u8108\u7d61\u53e2\u4e73\u982d\u816b\u306f\u7279\u306b\u96e3\u6613\u5ea6\u304c\u9ad8\u304f\uff0c\u67d4\u3089\u304b\u304f\u50b7\u3064\u304d\u3084\u3059\u3044\u65b0\u751f\u5150\u306e\u6df1\u90e8\u767d\u8cea\u306e\u640d\u50b7\uff0c\u8133\u5f13\u306e\u640d\u50b7\u306a\u3069\u624b\u8853\u76f4\u5f8c\u306b\u306f\u308f\u304b\u3089\u306a\u304f\u3066\u3082\uff0c\u5c06\u6765\u306e\u77e5\u7684\u767a\u80b2\u306b\u5927\u304d\u306a\u969c\u5bb3\u3092\u3042\u305f\u3048\u308b\u640d\u50b7\u3082\u3042\u308a\u5f97\u307e\u3059\u3002\u5316\u5b66\u7642\u6cd5\u3067\u8108\u7d61\u53e2\u816b\u760d\u3092\u7e2e\u5c0f\u3055\u305b\u308b\u3053\u3068\u304c\u3067\u304d\u308b\u306e\u3067\uff0c\u5927\u304d\u306a\u3082\u306e\u3067\u306f\u6458\u51fa\u8853\u306e\u524d\u306b\u8003\u616e\u3055\u308c\u308b\u3079\u304d\u3067\u3059\u3002<\/p>\n<p align=\"left\">\u65b0\u751f\u5150\u671f\u306e\u60aa\u6027\u816b\u760d\u306f\u5897\u5927\u901f\u5ea6\u304c\u65e9\u304f\u6458\u51fa\u3092\u3057\u306a\u3051\u308c\u3070\u306a\u3089\u306a\u3044\u306e\u3067\u3057\u3087\u3046\u304c\uff0c\u30ea\u30b9\u30af\u304c\u9ad8\u3059\u304e\u308b\u306e\u3067\uff0c\u305d\u3082\u305d\u3082\u6cbb\u7642\u3092\u3059\u308b\u3079\u304d\u304b\u3069\u3046\u304b\u306e\u96e3\u3057\u3044\u5224\u65ad\u306b\u306a\u308a\u307e\u3059\u3002<\/p>\n<p align=\"left\"><a href=\"\/sawamura\/wp\/wp-content\/uploads\/2014\/07\/newbornastrocytoma11.jpg\"><img loading=\"lazy\" decoding=\"async\" class=\"alignleft size-thumbnail wp-image-6109\" title=\"newbornastrocytoma1\" src=\"\/sawamura\/wp\/wp-content\/uploads\/2014\/07\/newbornastrocytoma11-200x200.jpg\" alt=\"\" width=\"200\" height=\"200\" \/><\/a><a href=\"\/sawamura\/wp\/wp-content\/uploads\/2014\/07\/newbornastrocytoma3.jpg\"><img loading=\"lazy\" decoding=\"async\" class=\"alignleft size-thumbnail wp-image-6110\" title=\"newbornastrocytoma3\" src=\"\/sawamura\/wp\/wp-content\/uploads\/2014\/07\/newbornastrocytoma3-200x200.jpg\" alt=\"\" width=\"200\" height=\"200\" \/><\/a><a href=\"\/sawamura\/wp\/wp-content\/uploads\/2014\/07\/newbornastrocytoma5.jpg\"><img loading=\"lazy\" decoding=\"async\" class=\"alignleft size-thumbnail wp-image-6113\" title=\"newbornastrocytoma\" src=\"\/sawamura\/wp\/wp-content\/uploads\/2014\/07\/newbornastrocytoma5-200x200.jpg\" alt=\"\" width=\"200\" height=\"200\" \/><\/a><\/p>\n<p align=\"left\">\u80ce\u5150\u816b\u760d\u3067\u3059\u3002\u5728\u80ce36\u9031\u306e\u30a8\u30b3\u30fc\u306b\u3066\u8133\u816b\u760d\u3068\u8a3a\u65ad\u3055\u308c\uff0c\u51fa\u751f\u76f4\u5f8c\u306b\u816b\u760d\u5185\u51fa\u8840\u3092\u7e70\u308a\u8fd4\u3057\u305f\u305f\u3081\uff0c\u751f\u5f8c3\u65e5\u76ee\u306b\u7dca\u6025\u624b\u8853\u3067\u816b\u760d\u5168\u6458\u51fa\u3092\u3057\u305f\u65b0\u751f\u5150\u306e\u5f8c\u982d\u8449\u306e\u5927\u304d\u306a\u661f\u7d30\u80de\u816b\u3067\u3059\u3002\u67d4\u3089\u304b\u3044\u816b\u760d\u7d44\u7e54\u304c\u81ea\u58ca\u3057\u3066\u51fa\u8840\u304c\u6fc0\u3057\u304f\uff0c\u7d50\u5c40\u816b\u760d\u3092\u5168\u6458\u51fa\u3057\u306a\u3051\u308c\u3070\u6b62\u8840\u306f\u3067\u304d\u307e\u305b\u3093\u3067\u3057\u305f\u3002\u5e78\u3044\u624b\u8853\u3092\u7d42\u3048\u308b\u3053\u3068\u304c\u3067\u304d\u305f\u304c\u8853\u4e2d\u306e\u8840\u5727\u4f4e\u4e0b\u306f\u5371\u6a5f\u7684\u306a\u3082\u306e\u3067\u3057\u305f\u3002\u75c5\u7406\u8a3a\u65ad\u306f\uff0c\u816b\u760d\u5206\u88c2\u50cf\u3092\u591a\u6570\u542b\u3080\u80a5\u80d6\u6027\u661f\u72b6\u7d30\u80de\u816b (gemistocytic astrocytoma, WHO grade 2) \u3067\u3057\u305f\u3002\u3053\u306e\u4f8b\u306f\u9577\u671f\u751f\u5b58\u3057\u3066\u3044\u307e\u3059\u304c\uff0c\u8853\u524d\u306b\u306f\u60aa\u6027\u5ea6\u306e\u9ad8\u3044\u795e\u7d4c\u81a0\u816b\u304c\u7591\u308f\u308c\u305f\u305f\u3081\u624b\u8853\u9069\u5fdc\u306e\u6c7a\u5b9a\u306b\u306f\u5c0f\u5150\u79d1\u533b\u3068\u306e\u9577\u3044\u8b70\u8ad6\u3092\u8981\u3057\u307e\u3057\u305f\u3002<\/p>\n<h4 align=\"left\"><strong>\u5947\u5f62\u816b<\/strong><\/h4>\n<p align=\"left\">\u5947\u5f62\u816b\u306f\u5148\u5929\u6027\u8133\u816b\u760d\u306e\u4e2d\u3067\u6700\u3082\u75c7\u4f8b\u6570\u306e\u591a\u3044\u816b\u760d\u3067\u3059\u3002\u4ed6\u306b\u53e3\u84cb\u88c2\uff0c\u8133\u6881\u3084\u55c5\u795e\u7d4c\u306e\u7121\u5f62\u6210\uff0c\u5916\u53cd\u8db3\u306a\u3069\u306e\u5408\u4f75\u5947\u5f62\u3092\u4f34\u3046\u3053\u3068\u304c\u3042\u308a\u307e\u3059\u3002\u75c5\u7406\u7d44\u7e54\u306f\uff0c\u6210\u719f\u5947\u5f62\u816b\u3068\u672a\u719f\u5947\u5f62\u816b\u304c\u5b58\u5728\u3057\uff0c\u3044\u305a\u308c\u3082\u8a3a\u65ad\u6642\u306b\u816b\u760d\u306e\u30b5\u30a4\u30ba\u304c\u5de8\u5927\u3067\u3042\u308b\u3053\u3068\u304c\u591a\u304f\uff0c\u75c5\u7406\u5b66\u7684\u60aa\u6027\u5ea6\u306b\u304b\u304b\u308f\u3089\u305a\u4e88\u5f8c\u4e0d\u826f\u3068\u3055\u308c\u308b\u300212\u4f8b\u306e\u5148\u5929\u6027\u5947\u5f62\u816b\u3092\u307e\u3068\u3081\u305fBuetow\u3089\u306e\u5831\u544a\u3067\u306f\u305d\u306e\u5e73\u5747\u751f\u5b58\u671f\u9593\u304c\u751f\u5f8c21\u65e5\u3067\u3042\u308b<sup>8)<\/sup>\u3002\u3057\u304b\u3057\uff0c\u816b\u760d\u30b5\u30a4\u30ba\u304c\u5c0f\u3055\u3044\u3082\u306e\u3084\u5168\u6458\u51fa\u304c\u53ef\u80fd\u306a\u3082\u306e\u306f\u751f\u547d\u4e88\u5f8c\u304c\u826f\u597d\u306710\u5e74\u4ee5\u4e0a\u306e\u751f\u5b58\u3082\u5831\u544a\u3055\u308c\u3066\u304a\u308a<sup>13)<\/sup>\uff0c\u5916\u79d1\u7684\u6458\u51fa\u3092\u7a4d\u6975\u7684\u306b\u884c\u3046\u4fa1\u5024\u304c\u3042\u308b\u3002\u75c5\u7406\u8a3a\u65ad\u304c\u672a\u719f\u5947\u5f62\u816b\u3067\u3042\u3063\u305f\u5834\u5408\u306b\u306e\u307f\u5316\u5b66\u7642\u6cd5\u3092\u8003\u616e\u3059\u308b\u3002<\/p>\n<p align=\"left\"><a href=\"\/sawamura\/wp\/wp-content\/uploads\/2014\/07\/newbornteratoma1.jpg\"><img loading=\"lazy\" decoding=\"async\" class=\"alignleft size-thumbnail wp-image-6114\" title=\"newbornteratoma1\" src=\"\/sawamura\/wp\/wp-content\/uploads\/2014\/07\/newbornteratoma1-200x200.jpg\" alt=\"\" width=\"200\" height=\"200\" \/><\/a><a href=\"\/sawamura\/wp\/wp-content\/uploads\/2014\/07\/newbornteratoma2.jpg\"><img loading=\"lazy\" decoding=\"async\" class=\"alignleft size-thumbnail wp-image-6115\" title=\"newbornteratoma2\" src=\"\/sawamura\/wp\/wp-content\/uploads\/2014\/07\/newbornteratoma2-200x200.jpg\" alt=\"\" width=\"200\" height=\"200\" \/><\/a><\/p>\n<p align=\"left\">\u751f\u4e0b\u6642\u3088\u308a\u9032\u884c\u6027\u306e\u982d\u56f2\u62e1\u5927\u3092\u5448\u3057\u305f\uff14\u30f5\u6708\u5973\u5150\u306e\u6210\u719f\u5947\u5f62\u816b\uff08\u5de6MRI\uff09\u3002\u5074\u982d\u90e8\u76ae\u819a\u306b\u816b\u760d\u306b\u307e\u3067\u9023\u7d9a\u3059\u308bdimple\u304c\u8a8d\u3081\u3089\u308c\u660e\u3089\u304b\u306b\u5148\u5929\u6027\u306e\u5947\u5f62\u816b\u3067\u3057\u305f\u3002\u53f3\u534a\u7403\u5168\u4f53\u3092\u5360\u62e0\u3059\u308b\u3088\u3046\u306a\u56a2\u80de\u3092\u4f34\u3046\u5de8\u5927\u306a\u4e2d\u982d\u84cb\u7aa9\u816b\u760d\u3092\u5168\u6458\u51fa\u3057\u305f\u304c\uff0c\u305d\u306e\u5f8c\u3053\u306e\u60a3\u5150\u306e\u8133\u7d44\u7e54\u306f\u9806\u8abf\u306b\u56de\u5fa9\u767a\u80b2\u3057\uff08\u53f3CT\uff09\u751f\u80b2\u3057\u3066\u3044\u307e\u3059\u3002<\/p>\n<h4 align=\"left\"><strong>\u661f\u7d30\u80de\u816b\u30fb\u81a0\u82bd\u816b<\/strong><\/h4>\n<p align=\"left\">\u4e21\u8005\u3068\u3082\u306b\u661f\u7d30\u80de\u7cfb\u816b\u760d\u3067\u3059\u3002\u3053\u308c\u3089\u306f\u306b\u30c6\u30f3\u30c8\u4e0a\uff08\u5927\u8133\u534a\u7403\uff09\u306b\u767a\u751f\u3059\u308b\u3053\u3068\u304c\u591a\u3044\u3067\u3059\u3002\u9650\u5c40\u6027\u661f\u7d30\u80de\u816b\u306f\u5916\u79d1\u7684\u5168\u6458\u51fa\u8853\u304c\u3067\u304d\u308c\u3070\u4e88\u5f8c\u306f\u826f\u597d\u3053\u3068\u3082\u3042\u308a\u307e\u3059\u3002\u6458\u51fa\u8853\u3068\u5316\u5b66\u7642\u6cd5\u3092\u4f75\u7528\u3057\u9577\u671f\u751f\u5b58\u304c\u78ba\u8a8d\u3055\u308c\u3066\u3044\u308b\u5831\u544a\u3082\u3042\u308a\u307e\u3059\u306e\u3067\u6cbb\u7642\u306b\u5024\u3059\u308b\u3082\u306e\u3067\u3059\u304c\uff0c\u6cbb\u7642\u3059\u308b\u3079\u304d\u304b\u3069\u3046\u304b\u306e\u6c7a\u65ad\u306f\u96e3\u3057\u3044\u3067\u3059\u3002\u4e00\u65b9\uff0c\u65b0\u751f\u5150\u306e\u81a0\u82bd\u816b\u306f\u751f\u547d\u4e88\u5f8c\u304c\u6975\u3081\u3066\u4e0d\u826f\u3067\u3059\u3002\u539f\u56e0\u3068\u3057\u3066\uff0c\u816b\u760d\u306e\u6025\u901f\u306a\u5897\u5927\u3068\u6458\u51fa\u5f8c\u306e\u65e9\u671f\u518d\u767a\uff0c\u816b\u760d\u304c\u51fa\u8840\u6027\u75c5\u5909\u3092\u4f34\u3046\u3053\u3068\u304c\u591a\u3044\u3053\u3068\uff0c\u816b\u760d\u5185\u306e\u5927\u304d\u306a\u52d5\u9759\u8108\u763b\u306e\u5f62\u6210\u306b\u3088\u308b\u5fc3\u4e0d\u5168\u306a\u3069\u304c\u5831\u544a\u3055\u308c\u3066\u3044\u307e\u3059\u3002\u5168\u8eab\u72b6\u614b\u306e\u6539\u5584\u3092\u307f\u306a\u3044\u307e\u307e\uff0c\u751f\u76f4\u5f8c\u304b\u3089\u751f\u5f8c2\u30f6\u6708\u306e\u9593\u306b\u6b7b\u4ea1\u3059\u308b\u30b1\u30fc\u30b9\u304c\u591a\u304f\uff0c\u3055\u3089\u306b\u5728\u80ce\u8a3a\u65ad\u3055\u308c\u305f\u81a0\u82bd\u816b\u3067\u306f\uff0c\u598a\u5a20\u4e2d\u306b\u80ce\u5150\u306e\u6b7b\u4ea1\u304c\u78ba\u8a8d\u3055\u308c\u305f\u5831\u544a\u3082\u3042\u308a\u307e\u3059\u3002\u307e\u305f\u5316\u5b66\u7642\u6cd5\u306e\u6709\u52b9\u6027\u306f\u4f4e\u3044\u816b\u760d\u3067\u3059\u3002<\/p>\n<h4 align=\"left\"><strong>\u672a\u5206\u5316\u795e\u7d4c\u5916\u80da\u8449\u6027\u816b\u760d\uff08PNET\uff09\u30fb\u9ac4\u82bd\u816b<\/strong><\/h4>\n<p align=\"left\">\u904e\u53bb\u306e\u5831\u544a\u3067\u306f\uff0c\u5c0f\u8133\u306b\u767a\u751f\u3059\u308b\u9ac4\u82bd\u816b\u3068\u30c6\u30f3\u30c8\u4e0a\u306b\u767a\u751f\u3059\u308b\u672a\u5206\u5316\u795e\u7d4c\u5916\u80da\u8449\u6027\u816b\u760d\uff08PNET\uff09\u3092\u3072\u3068\u3064\u306e\u30b0\u30eb\u30fc\u30d7\u3068\u3057\u3066\u53d6\u308a\u307e\u3068\u3081\u308c\u3070\uff0c\u661f\u7d30\u80de\u7cfb\u816b\u760d\u3068\u307b\u307c\u540c\u3058\u304f\u3089\u3044\u306e\u767a\u751f\u983b\u5ea6\u3068\u8003\u3048\u3089\u308c\u307e\u3059\u3002\u4e00\u822c\u306b\uff0c\u7d4c\u904e\u89b3\u5bdf\u3059\u308c\u3070\u816b\u760d\u306f\u6025\u901f\u306b\u5897\u5927\u3057\uff0c\u60a3\u5150\u306f\u77ed\u671f\u9593\u3067\u81f4\u6b7b\u7684\u72b6\u614b\u306b\u9665\u308b\u306e\u3067\uff0c\u6cbb\u7642\u3092\u884c\u3046\u3068\u306a\u308c\u3070\u65e9\u6025\u306b\u5916\u79d1\u6458\u51fa\u3042\u308b\u3044\u306f\u751f\u691c\u8853\u3092\u8a66\u307f\u308b\u5fc5\u8981\u304c\u3042\u308a\u307e\u3059\u3002\u6cbb\u7642\u6cd5\u306f\u5916\u79d1\u7684\u6458\u51fa\u8853\u3068\u5316\u5b66\u7642\u6cd5\u3092\u4f75\u7528\u3057\u305f\u3068\u3044\u3046\u5831\u544a\u304c\u3042\u308a\u307e\u3059\u3002\u4e88\u5f8c\u306b\u3064\u3044\u3066\u306f\uff0c\uff12\u5e74\u304b\u3089\uff19\u5e74\u306e\u9577\u671f\u306b\u308f\u305f\u308a\u816b\u760d\u518d\u767a\u3092\u8a8d\u3081\u306a\u304b\u3063\u305f\u3068\u3044\u3046\u5831\u544a\u3082\u3042\u308b\u306e\u3067\u3059\u304c\uff0c\u751f\u5f8c\uff11\u5e74\u4ee5\u5185\u306b\u591a\u6570\u304c\u6b7b\u4ea1\u3059\u308b\u3068\u3044\u3046\u5831\u544a\u304c\u591a\u3044\u3067\u3059\u3002\u3044\u305a\u308c\u306b\u305b\u3088\uff0c\u5316\u5b66\u7642\u6cd5\u304c\u594f\u52b9\u3057\u306a\u3051\u308c\u3070\u9577\u671f\u751f\u5b58\u306f\u671f\u5f85\u3067\u304d\u306a\u3044\u816b\u760d\u3067\u3059\u3002\u3082\u3061\u308d\u3093\u65b0\u751f\u5150\u671f\u3042\u308b\u3044\u306f\u4e73\u5150\u671f\u306b\u653e\u5c04\u7dda\u6cbb\u7642\u306f\u3067\u304d\u307e\u305b\u3093\u3002<\/p>\n<h4 align=\"left\"><strong>\u8108\u7d61\u53e2\u4e73\u982d\u816b<\/strong><\/h4>\n<p align=\"left\">\u521d\u671f\u75c7\u5019\u306f\u6c34\u982d\u75c7\u30fb\u982d\u56f2\u62e1\u5927\u3092\u5448\u3059\u308b\u3053\u3068\u304c\u307b\u3068\u3093\u3069\u3067\u3059\u3002\u816b\u760d\u306e\u767a\u751f\u90e8\u4f4d\u306f\uff0c\u5074\u8133\u5ba4\u8108\u7d61\u53e2\u304c\u6700\u3082\u591a\u304f\uff0c\u3064\u3044\u3067\u7b2c\uff14\u8133\u5ba4\u3042\u308b\u3044\u306f\u7b2c\uff13\u8133\u5ba4\u3067\u3046\u3002\u307e\u308c\u3067\u3059\u304c\u4e21\u5074\u6027\u306b\u767a\u751f\u3059\u308b\u3053\u3068\u304c\u3042\u308a\u307e\u3059\u3002\u816b\u760d\u304b\u3089\u306e\u8133\u5ba4\u5185\u51fa\u8840\u3092\u5408\u4f75\u3059\u308b\u3053\u3068\u306f\u73cd\u3057\u304f\u3042\u308a\u307e\u305b\u3093\u3002\u591a\u304f\u306f\u4e73\u982d\u764c\u3067\u306f\u306a\u304f\u826f\u6027\u306e\u4e73\u982d\u816b\u306a\u306e\u3067\uff0c\u5168\u6458\u51fa\u8853\u306b\u3088\u308a\u816b\u760d\u6b7b\u3092\u5b8c\u5168\u306b\u56de\u907f\u3059\u308b\u3053\u3068\u304c\u3067\u304d\uff0c\u5148\u5929\u6027\u8133\u816b\u760d\u306e\u4e2d\u3067\u306f\uff0c\u6700\u3082\u751f\u547d\u4e88\u5f8c\u304c\u826f\u597d\u3068\u3055\u308c\u308b\u816b\u760d\u3067\u3059\u3002\u9ac4\u6db2\u7523\u751f\u80fd\u3092\u6709\u3059\u308b\u8108\u7d61\u53e2\u4e73\u982d\u816b\u3067\u306f\uff0c\u30b7\u30e3\u30f3\u30c8\u8853\u306e\u307f\u3067\u591a\u91cf\u306e\u9ac4\u6db2\u7523\u751f\u3092\u30b3\u30f3\u30c8\u30ed\u30fc\u30eb\u3067\u304d\u306a\u3044\u306e\u3067\uff0c\u5c0f\u3055\u306a\u4e73\u982d\u816b\u3067\u3042\u3063\u3066\u3082\u4e73\u5150\u671f\u306b\u5168\u6458\u51fa\u3092\u884c\u308f\u3056\u308b\u3092\u5f97\u306a\u3044\u3053\u3068\u3082\u3042\u308a\u307e\u3059\u3002<\/p>\n<h4 align=\"left\"><strong>infantile hemispheric glioma\u306f3\u3064\u306b\u5206\u985e\u3055\u308c\u308b<\/strong><\/h4>\n<p>Guerreiro Stucklin AS: Alterations in ALK\/ROS1\/NTRK\/MET drive a group of <span class=\"highlight\">infantile<\/span> <span class=\"highlight\">hemispheric<\/span> gliomas. <span role=\"menubar\">Nat Commun.<\/span> 2019<br \/>\n\u4e73\u5150\u306e\u5927\u8133\u30b0\u30ea\u30aa\u30fc\u30de\u3067\u3059\u3002\u4f4e\u60aa\u6027\u5ea6 low-grade\u306e\u307b\u3046\u304c\u9ad8\u3044\u6b7b\u4ea1\u7387\u3068\u306a\u308a\u9ad8\u60aa\u6027\u5ea6 hi-grade \u306e\u3082\u306e\u306e\u307b\u3046\u304c\u3088\u3044\u3068\u3044\u3046\u9006\u8aac\u7684\u306a\u4e88\u5f8c\u3092\u305f\u3069\u308a\u307e\u3059\u3002Group 1, 2, and 3\u306b\u5206\u985e\u3067\u304d\u308b\u305d\u3046\u3067\u3059\u3002Group 1\u306f alterations in the receptor tyrosine kinases ALK, ROS1, NTRK and MET\u304c\u3042\u308a\u4e88\u5f8c\u306f\u4e2d\u9593\u7fa4\uff0cGroup2\u30683\u306fRAS\/MAPK pathway mutations\u304c\u3042\u308a\uff0cGroup 2\u3067\u306f\u975e\u5e38\u306b\u9577\u671f\u4e88\u5f8c\u304c\u826f\u3044\u306e\u306b\u5bfe\u3057\u3066\uff0cGroup 3\u3067\u306f\u653e\u5c04\u7dda\u5316\u5b66\u7642\u6cd5\u306b\u53cd\u5fdc\u3057\u306a\u3044\u3068\u3055\u308c\u307e\u3059\u3002<\/p>\n<h4 align=\"left\"><strong>\u6587\u732e<\/strong><\/h4>\n<ul>\n<li>Arnstein LH, et al: A case report and survey of brain tumors during the neonatal period. J Neurosurg 8: 315-319, 1951<\/li>\n<li>Guerreiro Stucklin AS: Alterations in ALK\/ROS1\/NTRK\/MET drive a group of <span class=\"highlight\">infantile<\/span> <span class=\"highlight\">hemispheric<\/span> gliomas. <span role=\"menubar\">Nat Commun.<\/span> 2019<\/li>\n<li>Solitare GB, et al: Congenital intracranial neoplasm. J Neuropathol Exp Neurol 2: 280-292, 1964<\/li>\n<li>Rickert CH, et al: Congenital immature teratoma of the fetal brain. Childs Nerv Syst 13: 556-559, 1997<\/li>\n<li>Jooma R, et al: Intracranial tumours in the first year of life. Neuroradiology 23: 267-274, 1982<\/li>\n<li>Balestrini MR, et al: Brain tumors with symptomatic onset in the first two years of life. Childs Nerv Syst 10: 104-110, 1994<\/li>\n<li>Rizk T, et al: Congenital brain tumor in a neonate conceived by in vitro fertilization. Childs Nerv Syst 16: 501-502, 2000<\/li>\n<li>Radkowski MA, et al: Neonatal brain tumors: CT and MR findings. J Comput Assist Tomogr 12: 10-20, 1988<\/li>\n<li>Buetow PC, et al: Congenital brain tumors: a review of 45 cases. AJR Am J Roentgenol 155: 587-593, 1990<\/li>\n<li>Parkes SE, et al: Neonatal tumours: a thirty-year population-based study. Med Pediatr Oncol 22: 309-317, 1994<\/li>\n<li>Wakai S, et al: Congenital brain tumors. Surg Neurol 21: 597-609, 1984<\/li>\n<li>Raisanen JM, et al: Congenital brain tumors. Pathology (Phila) 2: 103-116, 1993<\/li>\n<li>Oi S, et al: Massive congenital intracranial teratoma diagnosed in utero. Childs Nerv Syst 6: 459-461, 1990<\/li>\n<li>Nanda A, et al: Congenital forms of intracranial teratoma. Childs Nerv Syst 7: 112-114, 1991<\/li>\n<li>Lee DY, et al: Congenital glioblastoma diagnosed by fetal sonography. Childs Nerv Syst 15: 197-201, 1999<\/li>\n<li>Halperin EC, et al: Neonatal neoplasms. Int J Radiat Oncol Biol Phys 47: 171-178, 2000<\/li>\n<li>Mazzone D, et al: Report of a case of congenital glioblastoma multiforme: an immunohistochemical study. Childs Nerv Syst 11: 311-313, 1995<\/li>\n<li>McConachie NS, et al: Case report: antenatal diagnosis of congenital glioblastoma. Clin Radiol 44: 121-122, 1991<\/li>\n<li>Jooma R, et al: Intracranial tumors in neonates: a report of seventeen cases. Surg Neurol 21: 165-170, 1984<\/li>\n<li>Haddad SF, et al: Brain tumors occurring before 1 year of age: a retrospective reviews of 22 cases in an 11-year period (1977-1987). Neurosurgery 29: 8-13, 1991<\/li>\n<li>Girschick HJ, et al: Cytogenetic and histopathologic studies of congenital supratentorial primitive neuroectodermal tumors: a case report. Pathol Oncol Res 7: 67-71, 2001<\/li>\n<li>Anderson DR, et al: Radiologic-pathologic correlation. Congenital choroid plexus papillomas. AJNR Am J Neuroradiol 16: 2072-2076, 1995<\/li>\n<\/ul>\n<p align=\"left\">\n","protected":false},"excerpt":{"rendered":"<p>\u907a\u4f1d\u6027\u8133\u816b\u760d hereditary brain tumor, familial brain tumor \u5bb6\u65cf\u6027\u306b\u3042\u308b\u7279\u5b9a\u306e\u907a\u4f1d\u5b50\u306bgerm line mutation\u304c\u3042\u308a\u751f\u3058\u308b\u816b\u760d\u3067\u3059 \u5bb6\u65cf\u6027\u6d77\u7dbf\u72b6\u8840\u7ba1\u816b\uff08\u5225\u30da\u30fc\u30b8\u306a\u306e [&hellip;]<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[5],"tags":[],"class_list":["post-6015","post","type-post","status-publish","format-standard","hentry","category-pediattumor"],"aioseo_notices":[],"_links":{"self":[{"href":"https:\/\/plaza.umin.ac.jp\/sawamura\/wp-json\/wp\/v2\/posts\/6015","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/plaza.umin.ac.jp\/sawamura\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/plaza.umin.ac.jp\/sawamura\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/plaza.umin.ac.jp\/sawamura\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/plaza.umin.ac.jp\/sawamura\/wp-json\/wp\/v2\/comments?post=6015"}],"version-history":[{"count":33,"href":"https:\/\/plaza.umin.ac.jp\/sawamura\/wp-json\/wp\/v2\/posts\/6015\/revisions"}],"predecessor-version":[{"id":15264,"href":"https:\/\/plaza.umin.ac.jp\/sawamura\/wp-json\/wp\/v2\/posts\/6015\/revisions\/15264"}],"wp:attachment":[{"href":"https:\/\/plaza.umin.ac.jp\/sawamura\/wp-json\/wp\/v2\/media?parent=6015"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/plaza.umin.ac.jp\/sawamura\/wp-json\/wp\/v2\/categories?post=6015"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/plaza.umin.ac.jp\/sawamura\/wp-json\/wp\/v2\/tags?post=6015"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}