{"id":16353,"date":"2020-09-14T16:12:20","date_gmt":"2020-09-14T07:12:20","guid":{"rendered":"https:\/\/plaza.umin.ac.jp\/sawamura\/?p=16353"},"modified":"2020-09-14T17:23:38","modified_gmt":"2020-09-14T08:23:38","slug":"granularcellastrocytoma","status":"publish","type":"post","link":"https:\/\/plaza.umin.ac.jp\/sawamura\/glioma\/granularcellastrocytoma\/","title":{"rendered":"\u9846\u7c92\u7d30\u80de\u661f\u7d30\u80de\u816b granular cell astrocytoma GCA"},"content":{"rendered":"<ul>\n<li>\u3059\u3054\u304f\u7a00\u306a\u30b0\u30ea\u30aa\u30fc\u30de\u3067\u3059<\/li>\n<li>\u767a\u75c7\u5e74\u9f62\u4e2d\u592e\u5024\u306f50\u4ee3\u5f8c\u534a\uff0c\u524d\u982d\u8449\u3068\u5074\u982d\u8449\u306b\u591a\u304f\u767a\u751f\u3057\u307e\u3059<\/li>\n<li>IDH wild-type\u306e\u3073\u307e\u3093\u6027\u30b0\u30ea\u30aa\u30fc\u30de\uff0c\u661f\u7d30\u80de\u7cfb\u816b\u760d\u3067\u3059<\/li>\n<li>astrocytoma\u306esubtype \u3068\u3055\u308c\u3066\u3044\u307e\u3057\u305f\u304c\uff0cglioblastoma\u306b\u5c5e\u3059\u308b\u816b\u760d\u3068\u6349\u3048\u3089\u308c\u307e\u3059<\/li>\n<li>WHO\u57fa\u6e96\u306b\u3088\u308b\u7d44\u7e54\u5b66\u7684\u30b0\u30ec\u30fc\u30c9\u306f2, 3, 4\u306b\u76f8\u5f53\u3057\u307e\u3059<\/li>\n<li>macrophage\u306e\u3088\u3046\u306a\u5927\u304d\u306a\u80de\u4f53\u3092\u6709\u3057\uff0c\u597d\u9178\u6027\u9846\u7c92\u3092\u7d30\u80de\u8cea\u5185\u306b\u8c4a\u5bcc\u306b\u542b\u3080plump astrocytic cells\u9846\u7c92\u7d30\u80de\u3067\u69cb\u6210\u3055\u308c\u308b\u816b\u760d\u3067\u3059<\/li>\n<li>\u7d44\u7e54\u30b0\u30ec\u30fc\u30c9\u304c\u3069\u3046\u3042\u308c\u81e8\u5e8a\u7684\u306b\u306f\u30b0\u30ec\u30fc\u30c94\u3067\uff0c\u81a0\u82bd\u816b\u3068\u540c\u3058\u3067\u3059<\/li>\n<li>GFAP, OLIG2, \u00a0S100, CD68\u304c\u967d\u6027\u306b\u306a\u308a\u307e\u3059<\/li>\n<li>ATRX\u306f\u5909\u7570\u3057\u3066\u3044\u307e\u3059<\/li>\n<li>\u816b\u760d\u306e\u5916\u5468\u3042\u305f\u308a\u306b\u306f\uff0cplump astrocytes\u304c\u5c11\u306a\u304f\u306a\u308a\uff0c\u901a\u5e38\u306e\u3073\u307e\u3093\u6027\u661f\u7d30\u80de\u816b\u3068\u304a\u306a\u3058\u3088\u3046\u306a\u5c0f\u578b\u306ediffuse neoplastic astrocytes\u304c\u6d78\u6f64\u6027\u306b\u5e83\u7bc4\u56f2\u306b\u6d78\u6f64\u3057\u3066\u3044\u307e\u3059<\/li>\n<li>\u6cbb\u7642\u62b5\u6297\u6027\u816b\u760d\u3067\uff0c\u751f\u5b58\u671f\u9593\u4e2d\u592e\u5024\u306f1\u5e74\u307b\u3069\u3067\u3059<\/li>\n<\/ul>\n<p><a href=\"https:\/\/plaza.umin.ac.jp\/sawamura\/wp\/wp-content\/uploads\/2020\/09\/granularcellastrocytomatt1.jpg\"><img loading=\"lazy\" decoding=\"async\" class=\"alignleft size-medium wp-image-16358\" src=\"https:\/\/plaza.umin.ac.jp\/sawamura\/wp\/wp-content\/uploads\/2020\/09\/granularcellastrocytomatt1-300x285.jpg\" alt=\"\" width=\"300\" height=\"285\" srcset=\"https:\/\/plaza.umin.ac.jp\/sawamura\/wp\/wp-content\/uploads\/2020\/09\/granularcellastrocytomatt1-300x285.jpg 300w, https:\/\/plaza.umin.ac.jp\/sawamura\/wp\/wp-content\/uploads\/2020\/09\/granularcellastrocytomatt1-550x523.jpg 550w, https:\/\/plaza.umin.ac.jp\/sawamura\/wp\/wp-content\/uploads\/2020\/09\/granularcellastrocytomatt1-768x730.jpg 768w, https:\/\/plaza.umin.ac.jp\/sawamura\/wp\/wp-content\/uploads\/2020\/09\/granularcellastrocytomatt1.jpg 850w\" sizes=\"auto, (max-width: 300px) 100vw, 300px\" \/><\/a><a href=\"https:\/\/plaza.umin.ac.jp\/sawamura\/wp\/wp-content\/uploads\/2020\/09\/granularcellastrocytomatt2.jpg\"><img loading=\"lazy\" decoding=\"async\" class=\"alignleft size-medium wp-image-16359\" src=\"https:\/\/plaza.umin.ac.jp\/sawamura\/wp\/wp-content\/uploads\/2020\/09\/granularcellastrocytomatt2-300x270.jpg\" alt=\"\" width=\"300\" height=\"270\" srcset=\"https:\/\/plaza.umin.ac.jp\/sawamura\/wp\/wp-content\/uploads\/2020\/09\/granularcellastrocytomatt2-300x270.jpg 300w, https:\/\/plaza.umin.ac.jp\/sawamura\/wp\/wp-content\/uploads\/2020\/09\/granularcellastrocytomatt2-550x496.jpg 550w, https:\/\/plaza.umin.ac.jp\/sawamura\/wp\/wp-content\/uploads\/2020\/09\/granularcellastrocytomatt2-768x692.jpg 768w, https:\/\/plaza.umin.ac.jp\/sawamura\/wp\/wp-content\/uploads\/2020\/09\/granularcellastrocytomatt2.jpg 850w\" sizes=\"auto, (max-width: 300px) 100vw, 300px\" \/><\/a><\/p>\n<p><a href=\"https:\/\/plaza.umin.ac.jp\/sawamura\/wp\/wp-content\/uploads\/2020\/09\/granularcellastrocytomatt3.jpg\"><img loading=\"lazy\" decoding=\"async\" class=\"alignleft size-medium wp-image-16360\" src=\"https:\/\/plaza.umin.ac.jp\/sawamura\/wp\/wp-content\/uploads\/2020\/09\/granularcellastrocytomatt3-300x287.jpg\" alt=\"\" width=\"300\" height=\"287\" srcset=\"https:\/\/plaza.umin.ac.jp\/sawamura\/wp\/wp-content\/uploads\/2020\/09\/granularcellastrocytomatt3-300x287.jpg 300w, https:\/\/plaza.umin.ac.jp\/sawamura\/wp\/wp-content\/uploads\/2020\/09\/granularcellastrocytomatt3-550x527.jpg 550w, https:\/\/plaza.umin.ac.jp\/sawamura\/wp\/wp-content\/uploads\/2020\/09\/granularcellastrocytomatt3-768x735.jpg 768w, https:\/\/plaza.umin.ac.jp\/sawamura\/wp\/wp-content\/uploads\/2020\/09\/granularcellastrocytomatt3.jpg 850w\" sizes=\"auto, (max-width: 300px) 100vw, 300px\" \/><\/a><a href=\"https:\/\/plaza.umin.ac.jp\/sawamura\/wp\/wp-content\/uploads\/2020\/09\/granularcellastrocytomatt4.jpg\"><img loading=\"lazy\" decoding=\"async\" class=\"alignleft size-medium wp-image-16362\" src=\"https:\/\/plaza.umin.ac.jp\/sawamura\/wp\/wp-content\/uploads\/2020\/09\/granularcellastrocytomatt4-300x295.jpg\" alt=\"\" width=\"300\" height=\"295\" srcset=\"https:\/\/plaza.umin.ac.jp\/sawamura\/wp\/wp-content\/uploads\/2020\/09\/granularcellastrocytomatt4-300x295.jpg 300w, https:\/\/plaza.umin.ac.jp\/sawamura\/wp\/wp-content\/uploads\/2020\/09\/granularcellastrocytomatt4-550x542.jpg 550w, https:\/\/plaza.umin.ac.jp\/sawamura\/wp\/wp-content\/uploads\/2020\/09\/granularcellastrocytomatt4-768x756.jpg 768w, https:\/\/plaza.umin.ac.jp\/sawamura\/wp\/wp-content\/uploads\/2020\/09\/granularcellastrocytomatt4.jpg 850w\" sizes=\"auto, (max-width: 300px) 100vw, 300px\" \/><\/a><\/p>\n<p><a href=\"https:\/\/plaza.umin.ac.jp\/sawamura\/wp\/wp-content\/uploads\/2020\/09\/granularcellastrocytomatt5.jpg\"><img loading=\"lazy\" decoding=\"async\" class=\"alignleft size-medium wp-image-16363\" src=\"https:\/\/plaza.umin.ac.jp\/sawamura\/wp\/wp-content\/uploads\/2020\/09\/granularcellastrocytomatt5-288x300.jpg\" alt=\"\" width=\"288\" height=\"300\" srcset=\"https:\/\/plaza.umin.ac.jp\/sawamura\/wp\/wp-content\/uploads\/2020\/09\/granularcellastrocytomatt5-288x300.jpg 288w, https:\/\/plaza.umin.ac.jp\/sawamura\/wp\/wp-content\/uploads\/2020\/09\/granularcellastrocytomatt5-550x572.jpg 550w, https:\/\/plaza.umin.ac.jp\/sawamura\/wp\/wp-content\/uploads\/2020\/09\/granularcellastrocytomatt5-768x799.jpg 768w, https:\/\/plaza.umin.ac.jp\/sawamura\/wp\/wp-content\/uploads\/2020\/09\/granularcellastrocytomatt5.jpg 850w\" sizes=\"auto, (max-width: 288px) 100vw, 288px\" \/><\/a><\/p>\n<p>60\u4ee3\u306e\u60a3\u8005\u3055\u3093\u306e\u53f3\u524d\u982d\u8449\u6df1\u90e8\u304b\u3089\u5cf6\u56de\u306b\u767a\u751f\u3057\u305f\u3082\u306e\u3067\u3059\u3002\u521d\u767a\u75c7\u72b6\u306f\u75c7\u5019\u6027\u3066\u3093\u304b\u3093\u3067\u3059\u3002<br \/>\n\u30ac\u30c9\u30ea\u30cb\u30a6\u30e0\u5897\u5f37\u3055\u308c\u308b\u816b\u760d\u306e\u4e2d\u5fc3\u90e8\u306b\u58ca\u6b7b\u304c\u3042\u308a\uff0c\u60aa\u6027\u795e\u7d4c\u81a0\u816b\u3068\u3057\u3066\u306f\u816b\u760d\u5468\u56f2\u6d6e\u816b\u304c\u5f37\u3059\u304e\u308b\u3088\u3046\u306b\u898b\u3048\u308b\u306e\u3067\uff0c\u30ea\u30f3\u30d1\u816b PCNSL\u306b\u4f3c\u305f\u753b\u50cf\u6240\u898b\u3067\u3059\u3002<br \/>\n\u8131\u9ac4\u6027\u75be\u60a3\u3067\u3042\u308btumefactive multiple sclerosis\u306b\u753b\u50cf\u6240\u898b\u3082\u75c5\u7406\u6240\u898b\u3082\u985e\u4f3c\u3059\u308b\u3053\u3068\u304c\u3042\u308a\u307e\u3059\u3002<br \/>\nIDH1, IDH2\u306fwild type\u3067\u5909\u7570\u306a\u3057\uff0cATRX\u67d3\u8272\u967d\u6027\uff0cMIB-1 25%\u3068\u9ad8\u5024\u3067\u3057\u305f\u3002<br \/>\n60\u30b0\u30ec\u30a4\u306e\u5c40\u6240\u653e\u5c04\u7dda\u6cbb\u7642\u3092\u884c\u3044\u307e\u3057\u305f\u3002<\/p>\n","protected":false},"excerpt":{"rendered":"<p>\u3059\u3054\u304f\u7a00\u306a\u30b0\u30ea\u30aa\u30fc\u30de\u3067\u3059 \u767a\u75c7\u5e74\u9f62\u4e2d\u592e\u5024\u306f50\u4ee3\u5f8c\u534a\uff0c\u524d\u982d\u8449\u3068\u5074\u982d\u8449\u306b\u591a\u304f\u767a\u751f\u3057\u307e\u3059 IDH wild-type\u306e\u3073\u307e\u3093\u6027\u30b0\u30ea\u30aa\u30fc\u30de\uff0c\u661f\u7d30\u80de\u7cfb\u816b\u760d\u3067\u3059 astrocytoma\u306esubtype \u3068\u3055\u308c\u3066\u3044\u307e\u3057\u305f\u304c\uff0cglio [&hellip;]<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[16],"tags":[],"class_list":["post-16353","post","type-post","status-publish","format-standard","hentry","category-glioma"],"aioseo_notices":[],"aioseo_head":"\n\t\t<!-- 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