{"id":162,"date":"2012-04-19T02:05:16","date_gmt":"2012-04-18T17:05:16","guid":{"rendered":"\/sawamura\/wp\/?p=162"},"modified":"2024-05-24T17:08:46","modified_gmt":"2024-05-24T08:08:46","slug":"childtumor","status":"publish","type":"post","link":"https:\/\/plaza.umin.ac.jp\/sawamura\/pediattumor\/childtumor\/","title":{"rendered":"\u5c0f\u5150\u8133\u816b\u760d\u306e\u6cbb\u7642\u306b\u3064\u3044\u3066"},"content":{"rendered":"<div class=\"setumei\">\n<h4><span style=\"color: #000080;\">\u5c0f\u5150\u8133\u816b\u760d\u306e\u30b8\u30ec\u30f3\u30de<\/span><\/h4>\n<p>\u81ea\u5206\u306e\u5b50\u3069\u3082\u304c\u8133\u816b\u760d\u3060\u3068\u544a\u3052\u3089\u308c\u308b\u3068\uff0c\u89aa\u306f\u52d5\u63fa\u3057\u307e\u3059\u3002\u3000\u3069\u3046\u3057\u305f\u3089\u547d\u3092\u52a9\u3051\u3089\u308c\u308b\u3093\u3060\u308d\u3046\u304b\uff1f\u3000\u8a3a\u3066\u304f\u308c\u3066\u3044\u308b\u304a\u533b\u8005\u3055\u3093\u306f\uff0c\u3053\u306e\u75c5\u6c17\u306b\u8a73\u3057\u3044\u306e\u3060\u308d\u3046\u304b\uff1f\u3000\u4fe1\u7528\u3067\u304d\u308b\u3093\u3060\u308d\u3046\u304b\uff1f\u3000\u3069\u3053\u306e\u75c5\u9662\u306b\u884c\u3063\u305f\u3089\u3044\u3044\u3093\u3060\u308d\u3046\uff1f\u3000\u304a\u91d1\u306f\u3044\u304f\u3089\u304b\u304b\u308b\u3093\u3060\u308d\u3046\u304b\uff1f\u3000\u75c5\u6c17\u304c\u6cbb\u3063\u3066\u3082\u3072\u3069\u3044\u5f8c\u907a\u75c7\u304c\u6b8b\u308b\u3093\u3060\u308d\u3046\u304b\uff1f\u3000\u304a\u533b\u8005\u3055\u3093\u306b\u4f55\u3092\u805e\u3044\u305f\u3089\u3044\u3044\u306e\u3060\u308d\u3046\u304b\uff0c\u7d20\u4eba\u304c\u8cea\u554f\u3057\u305f\u3089\u5931\u793c\u306b\u306f\u306a\u3089\u306a\u3044\u3093\u306e\u3060\u308d\u3046\u304b\uff1f\u3000\u5b66\u6821\u3092\u3069\u306e\u304f\u3089\u3044\u4f11\u3093\u3060\u3089\u3044\u3044\u3093\u3060\u308d\u3046\uff1f\u3000\u5b50\u3069\u3082\u304c\u75db\u304f\u3066\u82e6\u3057\u3044\u601d\u3044\u3092\u3057\u306a\u3044\u306e\u3060\u308d\u3046\u304b\uff1f\u3000\u8ab0\u306b\u805e\u3044\u305f\u3089\u6700\u5584\u306e\u60c5\u5831\u304c\u5f97\u3089\u308c\u308b\u3093\u3060\u308d\u3046\uff1f<\/p>\n<p>\u3044\u308d\u3044\u308d\u306a\u7591\u554f\u304c\u7a81\u7136\uff0c\u982d\u3092\u3088\u304e\u308a\u307e\u3059\u3002\u3067\u3082\uff0c\u89aa\u306b\u306f\u4f55\u3082\u308f\u304b\u308a\u307e\u305b\u3093\u3002\u3067\u3082\u3084\u3063\u3071\u308a\u4e3b\u6cbb\u533b\u306e\u5148\u751f\u3092\u4fe1\u983c\u3057\u307e\u3057\u3087\u3046\uff01 \u4ee5\u524d\u3068\u6bd4\u8f03\u3059\u308c\u3070\uff0c\u4e2d\u898f\u6a21\u306a\u75c5\u9662\u3067\u6cbb\u7642\u3055\u308c\u308b\u3053\u3068\u306f\u307b\u3068\u3093\u3069\u306a\u304f\uff0c\u5927\u5b66\u75c5\u9662\u3084\u305d\u308c\u306b\u5339\u6575\u3059\u308b\u5927\u304d\u306a\u75c5\u9662\u306b\u5c0f\u5150\u8133\u816b\u760d\u306e\u60a3\u8005\u3055\u3093\u306f\u96c6\u307e\u3063\u3066\u3044\u307e\u3059\u3002<\/p>\n<p>\u6cbb\u7642\u6cd5\u304c\u8907\u96d1\u3059\u304e\u3066\uff0c\u30ac\u30a4\u30c9\u30e9\u30a4\u30f3\u3084\u30de\u30cb\u30e5\u30a2\u30eb\u3084\u30d7\u30ed\u30c8\u30b3\u30fc\u30eb\u306b\u66f8\u3044\u3066\u3042\u308b\u3068\u304a\u308a\u3067\u6700\u5584\u306e\u6cbb\u7642\u304c\u3067\u304d\u308b\u3088\u3046\u306a\u75c5\u6c17\u3067\u306f\u3042\u308a\u307e\u305b\u3093\u3002\u62c5\u5f53\u3059\u308b\u533b\u5e2b\u3082\uff0c\u3044\u308d\u3044\u308d\u306a\u5c02\u9580\u533b\u306b\u77e5\u8b58\u3084\u52a9\u529b\u3092\u6c42\u3081\u3066\uff0c\u6cbb\u7642\u306b\u5f53\u305f\u3089\u306a\u3051\u308c\u3070\u306a\u308a\u307e\u305b\u3093\u3002\u3082\u3057\uff0c\u305d\u308c\u304c\u3067\u304d\u306a\u3051\u308c\u3070\uff0c\u81ea\u5206\u3088\u308a\u5c0f\u5150\u8133\u816b\u760d\u306b\u8a73\u3057\u3044\u533b\u5e2b\u304c\u3044\u305f\u3089\uff0c\u81ea\u5206\u3067\u6cbb\u7642\u3057\u306a\u3044\u3067\u8ee2\u9662\u3055\u305b\u308b\u3053\u3068\u3092\u305f\u3081\u3089\u308f\u306a\u3044\u3067\u4e0b\u3055\u3044\u3002<\/p>\n<h4><strong><a title=\"\u30bd\u30d5\u30a3\u30fc\u306e\u9078\u629e\" href=\"\/sawamura\/pediattumor\/sophie\/\">\u3053\u3053\u3092\u30af\u30ea\u30c3\u30af\u3059\u308b\u3068\uff0c\u30bd\u30d5\u30a3\u30fc\u306e\u9078\u629e\u306e\u30da\u30fc\u30b8\u306b\u98db\u3073\u307e\u3059\u3002<\/a><\/strong><\/h4>\n<p style=\"text-align: center;\"><a href=\"\/sawamura\/wp\/wp-content\/uploads\/2012\/04\/owlchild.jpg\"><img loading=\"lazy\" decoding=\"async\" class=\"aligncenter size-full wp-image-2095\" title=\"Exif_JPEG_PICTURE\" src=\"\/sawamura\/wp\/wp-content\/uploads\/2012\/04\/owlchild.jpg\" alt=\"\" width=\"600\" height=\"849\" \/><\/a><\/p>\n<h5 style=\"text-align: left;\">\u3053\u3053\u304b\u3089\u4e0b\u306f\u5c02\u9580\u7684\u306a\u8a18\u8ff0\u306b\u306a\u308a\u307e\u3059<\/h5>\n<ul>\n<li>\u5c0f\u5150\u8133\u816b\u760d\u306e\u983b\u5ea6\u3068\u6b7b\u4ea1\u7387<\/li>\n<li>\u6cbb\u7642\u3092\u8003\u3048\u308b\u4e0a\u3067\u306e\u8133\u816b\u760d\u306e\u7279\u5fb4<\/li>\n<li>\u75c5\u7406\u8a3a\u65ad\u304c\u305f\u304f\u3055\u3093\u3042\u308b\u3053\u3068<\/li>\n<li>\u826f\u6027\u8133\u816b\u760d\u3068\u306f<\/li>\n<li>\u3067\u304d\u305f\u5834\u6240\u306b\u3088\u308b\u4e88\u5f8c\u306e\u9055\u3044<\/li>\n<li>\u5e74\u9f62\u306b\u3088\u308b\u6cbb\u7642\u6cd5\u306e\u9055\u3044<\/li>\n<li>\u5c0f\u5150\u8133\u816b\u760d\u306e\u81e8\u5e8a\u7814\u7a76\u306f\u96e3\u3057\u3044<\/li>\n<li>\u4ee3\u8868\u7684\u8133\u816b\u760d\u306e\u6cbb\u7642\u65b9\u91dd<\/li>\n<li>\u5c0f\u5150\u79d1\u533b\u3068\u8133\u5916\u79d1\u533b\u306e\u5f79\u5272<\/li>\n<li>\u307e\u3068\u3081<\/li>\n<\/ul>\n<h4><strong>\u5c0f\u5150\u8133\u816b\u760d\u306e\u983b\u5ea6\u3068\u6b7b\u4ea1\u7387<\/strong><\/h4>\n<p>\u767a\u751f\u6570\uff1a\u7c73\u56fd\u306eNCI\u306e2012\u5e74\u7d71\u8a08\u3067\u306f\uff0c15\u6b73\u672a\u6e80\u5c0f\u515010\u4e07\u4eba\u3042\u305f\u308a3.5\u4eba\u767a\u751f\u3059\u308b\u3068\u3055\u308c\u3066\u3044\u307e\u3059\u30022015\u5e74CBTRUS\u306e\u63a8\u8a08\u306b\u3088\u308c\u3070\uff0c\u7c73\u56fd\u306714\u6b73\u4ee5\u4e0b\u306e\u5c0f\u5150\u306b4,630\u4f8b\u767a\u751f\u3057\u307e\u3059\u306e\u3067\uff0c\u4eba\u53e3\u6bd4\u304b\u3089\u63a8\u8a08\u3059\u308b\u3068<strong><span style=\"color: #000080;\">\u65e5\u672c\u306b\u306f2016\u5e74\u306b1,900\u4f8b\u306e\u5c0f\u5150\u8133\u816b\u760d\u304c\u767a\u751f\u3057\u3066\u3044\u307e\u3059\u3002\u4e0a\u8a18\u306e\u7d71\u8a08\u306e\u30c7\u30fc\u30bf\u306f2000\u5e74\u3059\u304e\u304f\u3089\u3044\u306e\u3082\u306e\u3067\u3059\u3002\u4e00\u65b9\uff0c\u65e5\u672c\u306e\u51fa\u751f\u6570\u306f\u6fc0\u6e1b\u3057\u3066\u3044\u307e\u3059\u30022000\u5e74\u304c119\u4e07\u4eba\uff0c2022\u5e74\u306f79\u4e07\u4eba\u3067\u3059\u300234\uff05\u6e1b\u5c11\u3057\u304a\u3088\u305d3\u5206\u306e\uff12\u306b\u306a\u3063\u3066\u3044\u307e\u3059\u3002\u305d\u308c\u306b\u4f34\u3063\u3066\u5c0f\u5150\u8133\u816b\u760d\u306e\u767a\u751f\u6570\u3082\u6e1b\u5c11\u3057\uff0c\u307e\u3059\u307e\u3059\u73cd\u3057\u3044\u75c5\u6c17\u3068\u306a\u3063\u3066\u3044\u307e\u3059\u3002<\/span><\/strong><\/p>\n<p>\u6b7b\u4ea1\u6570\uff1a\u7c73\u56fd\u5c0f\u5150\u8133\u816b\u760d\u57fa\u91d1 PBTFUS\u306b\u3088\u308c\u3070\uff0c\u5c0f\u5150\u306e\u8133\u816b\u760d\u306f\u5c0f\u5150\u304c\u3093\u306e\u4e2d\u3067\u6700\u3082\u6b7b\u4ea1\u7387\u304c\u9ad8\u304f\u3066\uff0c34\u624d\u307e\u3067\u306e\u764c\u6b7b\u306e\u6700\u3082\u5927\u304d\u306a\u539f\u56e0\u3060\u3068\u3044\u3046\u3053\u3068\u3067\u3059\u3002<a href=\"http:\/\/seer.cancer.gov\/csr\/1975_2005\/results_single\/sect_28_table.03.pdf\" target=\"_blank\" rel=\"noopener noreferrer\">\u7c73\u56fdNCI\u306e2005\u5e74\u7d71\u8a08(SEER)<\/a>\u3067\u306f\uff0c14\u6b73\u307e\u3067\u306e\u5c0f\u5150\u3067\uff0c\u767d\u8840\u75c5 \u306e\u4eba\u53e310\u4e07\u3042\u305f\u308a\u306e\u6b7b\u4ea1\u7387(0.7)\u3068\u60aa\u6027\u8133\u816b\u760d\u306e\u6b7b\u4ea1\u7387 (0.7) \u306f\u307b\u307c\u540c\u5024\u3067\u3057\u305f\u3002\u767d\u8840\u75c5\u306e\u65b9\u304c\u767a\u751f\u6570\u305d\u306e\u3082\u306e\u304c\u591a\u3044\u306e\u3067\uff0c\u8133\u816b\u760d\u306e\u65b9\u304c\u6cbb\u308b\u78ba\u7387\u304c\u4f4e\u3044\u764c\u3067\u3042\u308b\u3053\u3068\u304c\u308f\u304b\u308a\u307e\u3059\u30022007\u5e74SEER\u7d71\u8a08\u3067\uff0c19\u6b73\u4ee5\u4e0b\u306e\u60aa\u6027\u816b\u760d\u306b\u3088\u308b\u6b7b\u4ea1\u6570\u306e\u7b2c\uff11\u4f4d\u306f\u767d\u8840\u75c5\uff0c\uff12\u4f4d\u304c\u8133\u816b\u760d\u3067\u3057\u305f\u30022016\u5e74\u306e<a href=\"http:\/\/www.cdc.gov\/nchs\/data\/databriefs\/db257.pdf\">NCHS (United States National Center for Health Statistics)\u306e\u7d71\u8a08<\/a>\u3067\u306f\uff0c19\u6b73\u307e\u3067\u306e\u5c0f\u5150\u30ac\u30f3\u306e\u6b7b\u4ea1\u6570\u306e29.9%\u304c\u8133\u816b\u760d\u6b7b\uff0c24.9%\u304c\u767d\u8840\u75c5\u6b7b\u3067\u3057\u305f\u3002<span style=\"color: #000080;\"><strong>\u5c0f\u5150\u8133\u816b\u760d\u306e\u6b7b\u4ea1\u6570\u306f\u767d\u8840\u75c5\u306e1.2\u500d\u306b\u76f8\u5f53\u3057\u307e\u3059\u3002<\/strong><span style=\"color: #333333;\">\u3053\u306e\u60aa\u6027\u816b\u760d\u6b7b\u3068\u3044\u3046\u3082\u306e\u306b\u3069\u306e\u7a0b\u5ea6\u306e\u826f\u6027\u8133\u816b\u760d\u304c\u542b\u307e\u308c\u3066\u3044\u308b\u306e\u304b\u306f\u308f\u304b\u308a\u307e\u305b\u3093\u304b\u3089\uff0c\u826f\u6027\u8133\u816b\u760d\u3092\u52a0\u3048\u308c\u3070\u8133\u816b\u760d\u6b7b\u306e\u65b9\u304c\u304b\u306a\u308a\u591a\u3044\u3068\u8003\u3048\u3089\u308c\u307e\u3059\u3002<\/span><\/span><\/p>\n<p>\u3057\u304b\u3057\u4e00\u65b9\u7c73\u56fd\u30671995\u5e74\u4ee5\u964d\uff0c\uff15\u5e74\u751f\u5b58\u5272\u5408\u306e\u660e\u3089\u304b\u306a\u6539\u5584\u304c\u3042\u308a\u307e\u3059\u3002<\/p>\n<p>\u6709\u75c5\u7387\uff1a2007\u5e7411\u6708\u306b\uff0c\u7c73\u56fd\u306eCBTRUS (The central brain tumor registry of the united states) \u306e\u4e8b\u52d9\u5c40\u306b\u76f4\u63a5\u5c0b\u306d\u305f\u3068\u3053\u308d\uff0c 2000\u5e74\u306e\u6642\u70b9\u3067\u306e19\u6b73\u4ee5\u4e0b\u306e\u60aa\u6027\u3068\u826f\u6027\u3092\u4f75\u305b\u305f\u5c0f\u5150\u8133\u816b\u760d\u306e\u767a\u751f\u7387\u306f\uff0c\u4eba\u53e310\u4e07\u4eba\u3042\u305f\u308a4.3\u4eba\u3060\u305d\u3046\u3067\u3059\u3002\u6709\u75c5\u7387\u306f9.5\u4eba\u304f\u3089\u3044\u3067\uff0c\u5c11\u306a\u304f\u3068\u308226,000\u4eba\u306e\u5b50\u4f9b\u304c\u8133\u816b\u760d\u306e\u8a3a\u65ad\u3092\u53d7\u3051\u3066\u751f\u304d\u3066\u3044\u308b\u305d\u3046\u3067\u3059\u3002<\/p>\n<p>\u3053\u306e\u4e8b\u5b9f\u306f\u65e5\u672c\u3067\u306f\u3042\u307e\u308a\u77e5\u3089\u308c\u3066\u3044\u307e\u305b\u3093\u3002\u816b\u760d\u304c\u3067\u304d\u308b\u81d3\u5668\u5225\u3067\u307f\u308c\u3070\uff0c\u65e5\u672c\u3067\u3082\u5c0f\u5150\u306b\u767a\u751f\u3059\u308b\u56fa\u5f62\u764c\u306e\u4e2d\u3067\u306f\u8133\u816b\u760d\u306f\u6700\u3082\u983b\u5ea6\u304c\u9ad8\u304f\u3066\uff0c\u767d\u8840\u75c5\u306b\u3088\u308b\u6b7b\u4ea1\u7387\u306e\u4f4e\u4e0b\u3068\u3068\u3082\u306b19\u624d\u4ee5\u4e0b\u306e\u764c\u6b7b\u306e\u4e2d\u3067\u306f\u8133\u816b\u760d\u304c\u6700\u5927\u306e\u539f\u56e0\u3067\u3059\u3002\u767d\u8840\u75c5\u306e\u6cbb\u7642\u304c\u6ce8\u76ee\u3055\u308c\u3066\u3069\u3093\u3069\u3093\u9032\u3093\u3067\u3044\u308b\u306e\u306b\uff0c\u8133\u816b\u760d\u306f\u7f6e\u304d\u53bb\u308a\u306e\u611f\u304c\u3042\u308a\u307e\u3059\u3002<\/p>\n<p>\u5e73\u621018\u5e74\u5ea6\u539a\u751f\u52b4\u50cd\u79d1\u5b66\u7814\u7a76\uff08\u5b50\u3069\u3082\u5bb6\u5ead\u7dcf\u5408\u7814\u7a76\u4e8b\u696d\uff09\u2028\u300c\u5c0f\u5150\u6162\u6027\u7279\u5b9a\u75be\u60a3\u6cbb\u7642\u7814\u7a76\u4e8b\u696d\u306e\u767b\u9332\u30fb\u7ba1\u7406\u30fb\u8a55\u4fa1\u30fb\u60c5\u5831\u63d0\u4f9b\u306b\u95a2\u3059\u308b\u7814\u7a76\u300d\u5e73\u621016\uff6417\u5e74\u5ea6\u5168\u56fd\u767b\u9332\u72b6\u6cc1\u3068\u3044\u3046\u306e\u304c\u30cd\u30c3\u30c8\u3067\u516c\u958b\u3055\u308c\u3066\u3044\u307e\u3059\u3002\u8133\u816b\u760d\u306e\u767a\u751f\u5b9f\u6570\u3092\u628a\u63e1\u3059\u308b\u306e\u306b\u5168\u304f\u5f79\u306b\u306f\u7acb\u3061\u307e\u305b\u3093\u304c\uff0c\u767d\u8840\u75c5\u306b\u6b21\u3044\u3067\u8133\u816b\u760d\u306e\u767a\u751f\u304c\u591a\u3044\u304b\u306a\uff1f\u304f\u3089\u3044\u306f\u7406\u89e3\u3067\u304d\u307e\u3059\u3002\u539a\u52b4\u7701\u306e\u4eba\u53e3\u52d5\u614b\u5e74\u5831\u5e73\u621012\u5e74\u3067\u306f\uff0c15\u6b73\u672a\u6e80\u306e\u539f\u56e0\u5225\u6b7b\u4ea1\u6570\u306f\u4e0d\u616e\u306e\u4e8b\u6545(933\u4eba)\u306b\u6b21\u3044\u3067\uff0c\u60aa\u6027\u65b0\u751f\u7269\u304c\uff12\u756a\u76ee(403\u4eba)\u3067\u3059\u3002<\/p>\n<p>\u65e5\u672c\u3067\u5c0f\u5150\u8133\u816b\u760d\u306e\u6b63\u78ba\u306a\u7d71\u8a08\u306f\u3068\u3089\u308c\u3066\u3044\u307e\u305b\u3093\u3002\u3044\u307e\u65e5\u672c\u3067\u305d\u308c\u3092\u77e5\u308b\u624b\u6bb5\u306f\u3042\u308a\u307e\u305b\u3093\u3057\uff0c\u4eca\u5f8c\u3082\u671f\u5f85\u3067\u304d\u307e\u305b\u3093\u3002<span style=\"color: #333333;\"><a style=\"color: #333333;\" href=\"medullo\/\" target=\"_blank\" rel=\"noopener noreferrer\">\u9ac4\u82bd\u816b<\/a><\/span>\u306f\uff0c\u5c0f\u5150\u306e\u60aa\u6027\u8133\u816b\u760d\u3068\u3057\u3066\u6700\u3082\u6709\u540d\u3067\u3059\u3002\u9ac4\u82bd\u816b\u306e\u5e74\u9593\u767a\u751f\u7387\u306f10\u4e07\u4eba\u3042\u305f\u308a0.06-0.07\u4eba\u304f\u3089\u3044\u3067\u3057\u3087\u3046\u304b\u3089\uff0c\u767a\u751f\u6570\u306f\u5168\u56fd\u30671\u5e74\u3042\u305f\u308a80\u4f8b\u5f37\u3068\u63a8\u5b9a\u3055\u308c\u307e\u3059\u3002\u9ac4\u82bd\u816b\u306f15\u6b73\u672a\u6e80\u306e\u5c0f\u5150\u8133\u816b\u760d\u306e\u7d0410%\u3092\u5360\u3081\u308b\u306e\u3067\uff0c\u5c0f\u5150\u8133\u816b\u760d\u306e\u767a\u751f\u7387\u306f\u5168\u4eba\u53e310\u4e07\u3042\u305f\u308a\u5e74\u95931\u4eba\u5f31\u306a\u306e\u304b\u3082\u3057\u308c\u307e\u305b\u3093\u3002\u7c73\u56fd\u3068\u540c\u69d8\u306b\u8003\u3048\u308c\u3070\uff0c\u5c0f\u5150\u4eba\u53e310\u4e07\u3042\u305f\u308a4.3\u4eba\u306a\u306e\u3067\u3059\u304c\uff0c\u5168\u304f\u63a8\u6e2c\u3067\u304d\u306a\u3044\u72b6\u6cc1\u3067\u3059\u3002\u7c73\u56fd\u306e\u4eba\u53e3\u306f\u65e5\u672c\u306e2.2\u500d\u306a\u306e\u3067\uff0c\u540c\u3058\u3088\u3046\u306b\u63a8\u6e2c\u3059\u308c\u3070<strong><span style=\"color: #000080;\">\u5c11\u306a\u304f\u3068\u308212,000\u4eba\u306e\u5b50\u4f9b\u305f\u3061\u304c\u8133\u816b\u760d\u306e\u8a3a\u65ad\u3092\u53d7\u3051\u3066\u751f\u304d\u3066\u3044\u308b<\/span><\/strong>\u3053\u3068\u306b\u306a\u308a\u307e\u3059\u3002<\/p>\n<hr \/>\n<p>\u5f8c\u3067\u8ff0\u3079\u308b\u3088\u3046\u306b\u5c0f\u5150\u8133\u816b\u760d\u306e\u6cbb\u7642\u306e\u9078\u629e\u80a2\u306f\u3068\u3066\u3082\u8907\u96d1\u3067\u3059\u304b\u3089\uff0c\u6700\u3082\u6709\u540d\u306a\u9ac4\u82bd\u816b\u306b\u304a\u3044\u3066\u3055\u3048\u3082\u5358\u7d14\u306b\u5224\u65ad\u3067\u304d\u3066\u9078\u3079\u308b\u6a19\u6e96\u7684\u6cbb\u7642\u3068\u3044\u3046\u3082\u306e\u304c\u3042\u308a\u307e\u305b\u3093\u3002\u3067\u3059\u304b\u3089\u5c0f\u5150\u8133\u816b\u760d\u306e\u6cbb\u7642\u65b9\u91dd\u3068\u3044\u3046\u554f\u984c\u3092\u7c21\u5358\u306b\u66f8\u304f\u3053\u3068\u306f\u3067\u304d\u307e\u305b\u3093\u304c\uff0c\u826f\u6027\u816b\u760d\u306e\u6cbb\u7642\u3082\u542b\u3081\u3066\uff0c\u6700\u65b0\u306e\u6cbb\u7642\u6307\u91dd\u3068\u306f\u4f55\u304b\u3092\u8003\u3048\u308b\u305f\u3081\u306e\u53c2\u8003\u3068\u306a\u308b\u3053\u3068\u3092\u8a18\u8f09\u3057\u307e\u3059\u3002<\/p>\n<h4>\u6cbb\u7642\u3092\u8003\u3048\u308b\u4e0a\u3067\u306e\u8133\u816b\u760d\u306e\u7279\u5fb4<\/h4>\n<h5>1. \u816b\u760d\u306e\u75c5\u7406\u8a3a\u65ad\u304c\u305f\u304f\u3055\u3093\u3042\u308b\u3053\u3068<\/h5>\n<p>\u4ed6\u306e\u81d3\u5668\u306b\u767a\u751f\u3059\u308b\u5c0f\u5150\u306e\u816b\u760d\u3068\u6bd4\u3079\u305f\u3068\u304d\uff0c\u5c0f\u5150\u306e\u8133\u816b\u760d\u306e\u6700\u5927\u306e\u7279\u5fb4\u306f\uff0c\u75c5\u7406\u7d44\u7e54\u304c\u5b9f\u306b\u591a\u5f69\u306a\u3053\u3068\u3067\u3059\u3002\u65e5\u672c\u8133\u816b\u760d\u7d71\u8a08\u306b\u3088\u308b14\u6b73\u4ee5\u4e0b\u306e\u8133\u816b\u760d\u306e\u75c5\u7406\u7d44\u7e54\u578b\u5225\u983b\u5ea6\u306f\uff0c<a href=\"..\/braintumors\/astrocytictumor\/\" target=\"_blank\" rel=\"noopener noreferrer\">\u661f\u7d30\u80de\u816b\u30b0\u30ec\u30fc\u30c92<\/a>\u304c19%\u3067\uff0c<a href=\"medullo\/\" target=\"_blank\" rel=\"noopener noreferrer\">\u9ac4\u82bd\u816b <\/a>(11.9%)\uff0c<a href=\"germinoma\/\" target=\"_blank\" rel=\"noopener noreferrer\">\u80da\u816b\uff08\u30b8\u30e3\u30fc\u30df\u30ce\u30fc\u30de\uff09<\/a>(9.5%)\uff0c<a href=\"..\/braintumors\/cranio\/\" target=\"_blank\" rel=\"noopener noreferrer\">\u982d\u84cb\u54bd\u982d\u816b<\/a>(8.9%)\uff0c<a href=\"..\/braintumors\/astrocytictumor\/\" target=\"_blank\" rel=\"noopener noreferrer\">\u661f\u7d30\u80de\u816b\u30b0\u30ec\u30fc\u30c9\uff13<\/a>(5.7%)\uff0c<a href=\"ependy\/\" target=\"_blank\" rel=\"noopener noreferrer\">\u4e0a\u8863\u816b <\/a>(4.5%)\uff0c<a href=\"..\/braintumors\/astrocytictumor\/\" target=\"_blank\" rel=\"noopener noreferrer\">\u81a0\u82bd\u816b<\/a>(3.5%)\u306a\u3069\u304c\u7d9a\u304d\u307e\u3059\u3002\u3067\u3082\uff0c\u6bdb\u69d8\u7d30\u80de\u6027\u661f\u7d30\u80de\u816b\u304c\u4e00\u756a\u591a\u3044\u306f\u305a\u3067\u3059\u304b\u3089\uff0c\u3053\u306e\u7d71\u8a08\u306f\u307b\u3068\u3093\u3069\u4fe1\u7528\u3067\u304d\u307e\u305b\u3093\u3002<\/p>\n<p>\u305d\u306e\u4ed6\u306e\u8133\u816b\u760d\u306e\u983b\u5ea6\u306f\u3068\u3066\u3082\u4f4e\u304f\u3066\u307e\u308c\u306a\u3082\u306e\u306b\u306a\u308a\u307e\u3059\u3002\u4e0a\u8a18\u4ee5\u5916\u3067\u653e\u5c04\u7dda\u3084\u5316\u5b66\u7642\u6cd5\u3092\u7528\u3044\u308b\u3082\u306e\u306b\uff0c<a href=\"pilo\/\" target=\"_blank\" rel=\"noopener noreferrer\">\u6bdb\u69d8\u7d30\u80de\u6027\u661f\u7d30\u80de\u816b<\/a>\uff0c<a href=\"\/sawamura\/glioma\/diffusemidlineglioma\/\" target=\"_blank\" rel=\"noopener noreferrer\">\u3073\u307e\u3093\u6027\u6a4b\u81a0\u816b\uff0f\u3073\u307e\u3093\u6027\u6b63\u4e2d\u30b0\u30ea\u30aa\u30fc\u30de<\/a>\uff0c<a href=\"..\/braintumors\/olig\/\" target=\"_blank\" rel=\"noopener noreferrer\">\u4e4f\u7a81\u8d77\u81a0\u816b<\/a>\uff0c<a href=\"ependy\/\" target=\"_blank\" rel=\"noopener noreferrer\">\u9000\u5f62\u6210\u6027\u4e0a\u8863\u816b<\/a>\uff0c<a href=\"germ\/\" target=\"_blank\" rel=\"noopener noreferrer\">\u80ce\u5150\u6027\u764c<\/a>\uff0c<a href=\"germ\/\" target=\"_blank\" rel=\"noopener noreferrer\">\u672a\u719f\u5947\u5f62\u816b\uff0c\u60aa\u6027\u5947\u5f62\u816b\uff0c\u6df7\u5408\u6027\u80da\u7d30\u80de\u816b\u760d\uff0c\u5375\u9ec4\u56a2\u816b\uff0c\u7d68\u6bdb\u4e0a\u76ae\u764c<\/a>\uff0c<a href=\"..\/braintumors\/lymphoma\/\" target=\"_blank\" rel=\"noopener noreferrer\">\u4e2d\u67a2\u795e\u7d4c\u539f\u767a\u30ea\u30f3\u30d1\u816b(PCNSL)<\/a>\uff0c<a href=\"..\/braintumors\/pinealtumor\/\" target=\"_blank\" rel=\"noopener noreferrer\">\u677e\u679c\u4f53\u82bd\u816b\uff0c\u4e2d\u9593\u578b\u677e\u679c\u4f53\u5b9f\u8cea\u816b\u760d (PPTID)<\/a>\u00a0\uff0c<a href=\"\/sawamura\/braintumors\/neuroblastoma\/\">\u5927\u8133\u795e\u7d4c\u82bd\u816b<\/a>\uff0c<a href=\"\/sawamura\/braintumors\/neuroblastoma\/\">\u55c5\u795e\u7d4c\u82bd\u816b<\/a>\uff0c<a href=\"..\/braintumors\/centralneuro\/\" target=\"_blank\" rel=\"noopener noreferrer\">\u7570\u578b\u4e2d\u67a2\u795e\u7d4c\u7d30\u80de\u7a2e<\/a>\uff0c<a href=\"..\/braintumors\/gangliocyto\/\" target=\"_blank\" rel=\"noopener noreferrer\">\u795e\u7d4c\u7bc0\u81a0\u816b<\/a>\uff0c<a href=\"choroidplexus\/\" target=\"_blank\" rel=\"noopener noreferrer\">\u8108\u7d61\u53e2\u4e73\u982d\u764c<\/a>\uff0c<a href=\"atrt\/\">\u975e\u5b9a\u578b\u5947\u5f62\u816b\u69d8\uff0f\u30e9\u30d6\u30c9\u30a4\u30c9\u816b\u760d(AT\/RT)<\/a>\uff0c<a href=\"\/sawamura\/pediattumor\/etmr-etantr\/\">ETMR\/ETANTR<\/a>\uff0c<a href=\"\/sawamura\/braintumors\/rosetteformingtumor\/\">\u30ed\u30bc\u30c3\u30c8\u5f62\u6210\u6027\u30b0\u30ea\u30a2\u795e\u7d4c\u7d30\u80de\u816b\u760d RGNT<\/a>\uff0c<a href=\"medullo\/\" target=\"_blank\" rel=\"noopener noreferrer\">\u9ac4\u82bd\u816b\uff0c<\/a><a href=\"\/sawamura\/braintumors\/schwann\/\" target=\"_blank\" rel=\"noopener noreferrer\">\u60aa\u6027\u672b\u68a2\u795e\u7d4c\u9798\u816b(MPNST)<\/a>\uff0c\u8edf\u9aa8\u8089\u816b\uff0c<a href=\"\/sawamura\/pediattumor\/neurocutaneous-melanosis\/\">\u9ac4\u819c\u9ed2\u8272\u816b<\/a>\uff0c<a title=\"\u9ac4\u819c\u816b\" href=\"\/sawamura\/braintumors\/meningioma\/\">\u975e\u5b9a\u578b\u9ac4\u819c\u816b\uff0c\u9000\u5f62\u6210\u6027\u9ac4\u819c\u816b<\/a>\uff0c<a href=\"\/sawamura\/braintumors\/langerhans\/\">\u30e9\u30f3\u30b2\u30eb\u30cf\u30f3\u30b9\u7d30\u80de\u7d44\u7e54\u7403\u75c7(LCH)<\/a>\u306a\u3069\u304c\u3042\u308a\u307e\u3059\u3002<\/p>\n<p>\u624b\u8853\u6458\u51fa\u304c\u4e3b\u3068\u3057\u3066\u884c\u308f\u308c\u308b\u5c0f\u5150\u816b\u760d\u306b<a href=\"..\/braintumors\/pituitary\/\" target=\"_blank\" rel=\"noopener noreferrer\">\uff0c\u5404\u7a2e\u6a5f\u80fd\u6027\u817a\u816b\u3092\u542b\u3080\u4e0b\u5782\u4f53\u817a\u816b<\/a>\uff0c<a href=\"..\/braintumors\/acoustictumor\/\" target=\"_blank\" rel=\"noopener noreferrer\">\u30b7\u30e5\u30ef\u30f3\u7d30\u80de\u816b\uff08\u795e\u7d4c\u9798\u816b\uff09<\/a>\uff0c<a href=\"..\/braintumors\/neurofibromatosis\/\">\u795e\u7d4c\u7dda\u7dad\u816b<\/a>\uff0c<a href=\"..\/braintumors\/meningioma\/\" target=\"_blank\" rel=\"noopener noreferrer\">\u9ac4\u819c\u816b<\/a>\uff0c<a href=\"..\/braintumors\/hemangioblastoma\/\" target=\"_blank\" rel=\"noopener noreferrer\">\u8840\u7ba1\u82bd\u816b<\/a><a href=\"\/sawamura\/braintumors\/hemangioblastoma\/\">\uff08VHL \u30d5\u30a9\u30f3\u30fb\u30d2\u30c3\u30da\u30eb\u30fb\u30ea\u30f3\u30c9\u30a6\u75c5\uff09<\/a>\uff0c<a href=\"..\/braintumors\/cavernoma\/\" target=\"_blank\" rel=\"noopener noreferrer\">\u6d77\u7dbf\u72b6\u8840\u7ba1\u816b<\/a>\uff0c\u5358\u7d14\u6027(\u82e5\u5e74\u6027)\u8840\u7ba1\u816b\uff0c<a href=\"..\/braintumors\/rathoke\/\" target=\"_blank\" rel=\"noopener noreferrer\">\u30e9\u30c8\u30b1\u306e\u3046\u80de<\/a>\uff0c<a href=\"..\/braintumors\/epidermoid\/\">\u985e\u8868\u76ae\u306e\u3046\u80de<\/a>\uff0c<a href=\"..\/braintumors\/dermoid\/\">\u985e\u76ae\u306e\u3046\u80de<\/a>\uff0c<a href=\"germ\/\" target=\"_blank\" rel=\"noopener noreferrer\">\u6210\u719f\u5947\u5f62\u816b<\/a>\uff0c<a href=\"..\/braintumors\/pinealtumor\/\" target=\"_blank\" rel=\"noopener noreferrer\">\u677e\u679c\u4f53\u7d30\u80de\u816b<\/a>\uff0c<a title=\"\u4e0a\u8863\u4e0b\u5de8\u7d30\u80de\u6027\u661f\u7d30\u80de\u816b\" href=\"\/sawamura\/pediattumor\/subepgiantastro\/\">\u4e0a\u8863\u4e0b\u5de8\u7d30\u80de\u6027\u661f\u7d30\u80de\u816b<\/a><a href=\"\/sawamura\/pediattumor\/subepgiantastro\/\">\u00a0(SEGA)<\/a>\uff0c<a title=\"\u4e0a\u8863\u4e0b\u816b\" href=\"\/sawamura\/braintumors\/glioma\/subependymoma\/\">\u4e0a\u8863\u4e0b\u816b<\/a>\uff0c<a href=\"choroidplexus\/\" target=\"_blank\" rel=\"noopener noreferrer\">\u8108\u7d61\u53e2\u4e73\u982d\u816b<\/a>\uff0c<a href=\"..\/braintumors\/centralneuro\/\" target=\"_blank\" rel=\"noopener noreferrer\">\u4e2d\u67a2\u6027\u795e\u7d4c\u7d30\u80de\u816b\uff0c<\/a><a href=\"..\/braintumors\/gangliocyto\/\" target=\"_blank\" rel=\"noopener noreferrer\">\u795e\u7d4c\u7bc0\u7d30\u80de\u816b\uff0c\u795e\u7d4c\u7bc0\u81a0\u816b\uff0c<\/a><a href=\"dnt\/\" target=\"_blank\" rel=\"noopener noreferrer\">\u80da\u82bd\u7570\u5f62\u6210\u6027\u795e\u7d4c\u4e0a\u76ae\u816b\u760d(DNT)\uff0c<\/a><a href=\"desmoinfantile\/\" target=\"_blank\" rel=\"noopener noreferrer\">\u7dda\u7dad\u5f62\u6210\u6027\u4e73\u5150\u795e\u7d4c\u7bc0\u81a0\u816b(DIA\/DIG)<\/a>\uff0c<a href=\"\/sawamura\/pediattumor\/lhermitteduclosdisease\/\" target=\"_blank\" rel=\"noopener noreferrer\">\u30ec\u30eb\u30df\u30c3\u30c8\u30fb\u30c0\u30af\u30ed\u30b9\u75c5\uff0f\u5c0f\u8133\u7570\u5f62\u6210\u6027\u795e\u7d4c\u7bc0\u7d30\u80de\u816b<\/a>\uff0c<a href=\"\/sawamura\/braintumors\/hemangioperi\/\">\u8840\u7ba1\u5916\u76ae\u816b<\/a>\uff0c<a href=\"..\/braintumors\/skulltumor\/\" target=\"_blank\" rel=\"noopener noreferrer\">\u810a\u7d22\u816b<\/a>\uff0c\u4e73\u5150\u5148\u5929\u6027\u8840\u7ba1\u816b\uff0c\u9aa8\u816b\uff0c\u8edf\u9aa8\u816b\uff0c<a href=\"..\/braintumors\/skulltumor\/\" target=\"_blank\" rel=\"noopener noreferrer\">\u7dda\u7dad\u6027\u7570\u5f62\u6210\u75c7<\/a>\uff0c<a href=\"\/sawamura\/braintumors\/endodermalcyst\/\">\u5185\u80da\u8449\u6027\u306e\u3046\u80de<\/a>\uff0c<a href=\"\/sawamura\/braintumors\/endodermalcyst\/\">\u795e\u7d4c\u8178\u306e\u3046\u80de<\/a>\uff0c<a title=\"\u30b3\u30ed\u30a4\u30c9\u56a2\u80de\" href=\"\/sawamura\/braintumors\/colloidcyst-2\/\" target=\"_blank\" rel=\"noopener noreferrer\">\u7b2c3\u8133\u5ba4\u30b3\u30ed\u30a4\u30c9\u56a2\u80de<\/a>\uff0c<a href=\"..\/braintumors\/pinealcyst\/\" target=\"_blank\" rel=\"noopener noreferrer\">\u677e\u679c\u4f53\u306e\u3046\u80de<\/a>\uff0c<a href=\"\/sawamura\/pediattumor\/hamartoma\/\" target=\"_blank\" rel=\"noopener noreferrer\">\u8996\u5e8a\u4e0b\u90e8\u904e\u8aa4\u816b<\/a>\uff0c\u7570\u6240\u6027\u7070\u767d\u8cea\uff0c<a href=\"\/sawamura\/braintumors\/lipom\/\" target=\"_blank\" rel=\"noopener noreferrer\">\u8102\u80aa\u816b<\/a>\u3001<a href=\"..\/braintumors\/neurofibromatosis\/\" target=\"_blank\" rel=\"noopener noreferrer\">NF-1\u3068NF-2\u95a2\u9023\u904e\u8aa4\u816b<\/a>\uff0c<a title=\"\u661f\u82bd\u7d30\u80de\u816b astroblastoma\" href=\"\/sawamura\/braintumors\/glioma\/astroblastoma\/\">\u661f\u82bd\u7d30\u80de\u816b\uff08\u30a2\u30b9\u30c8\u30ed\u30d6\u30e9\u30b9\u30c8\u30fc\u30de\uff09<\/a>\u306a\u3069\u304c\u3042\u308a\u307e\u3059\u304c\uff0c\u3055\u3089\u306b\u7d30\u5206\u985e\u3092\u3059\u308c\u3070\u9650\u308a\u304c\u3042\u308a\u307e\u305b\u3093\u3002<\/p>\n<p>\u3067\u3059\u304b\u3089\u5c0f\u5150\u306e\u8133\u816b\u760d\u3092\u6cbb\u7642\u3059\u308b\u533b\u5e2b\u306f\uff0c\u3053\u308c\u3089\u306e\u5168\u3066\u3092\u7406\u89e3\u3057\u3066\u3044\u306a\u3051\u308c\u3070\u306a\u3089\u306a\u3044\u306e\u3067\uff0c\u9014\u65b9\u3082\u306a\u3044\u77e5\u8b58\u3092\u6c42\u3081\u3089\u308c\u307e\u3059\u3002\u4f8b\u3048\u3070\u5c0f\u5150\u306e\u767d\u8840\u75c5\u306e\u6cbb\u7642\u304c\u3067\u304d\u308b\u304b\u3089\u3068\u3044\u3063\u3066\uff0c\u5c0f\u5150\u306e\u8133\u816b\u760d\u306e\u6cbb\u7642\u304c\u3067\u304d\u308b\u3068\u306f\u9650\u308a\u307e\u305b\u3093\u3057\uff0c\u8133\u816b\u760d\u306e\u624b\u8853\u304c\u4e0a\u624b\u3060\u304b\u3089\u3068\u3044\u3063\u3066\u8133\u816b\u760d\u306e\u5316\u5b66\uff08\u85ac\u7269\uff09\u7642\u6cd5\u304c\u308f\u304b\u308b\u3068\u306f\u3044\u3048\u307e\u305b\u3093\u3002<strong><span style=\"color: #333399;\">\u6cbb\u7642\u3092\u59cb\u3081\u308b\u524d\u306b\uff0c\u5c0f\u5150\u8133\u816b\u760d\u306b\u3068\u3066\u3082\u8a73\u3057\u3044\u5148\u751f\u306b\u5de1\u308a\u4f1a\u3048\u308b\u304b<\/span><\/strong>\u3069\u3046\u304b\u304c\u91cd\u8981\u306b\u306a\u308a\u307e\u3059\u3002<\/p>\n<p>\u3061\u306a\u307f\u306b\u79c1\u306f\uff0c\u4e0a\u306b\u66f8\u3044\u305f\u5168\u3066\u306e\u5c0f\u5150\u8133\u816b\u760d\u3092\u6cbb\u7642\u3057\u305f\u7d4c\u9a13\u304c\u3042\u308a\u307e\u3059\u304c\uff0c\u305d\u308c\u305e\u308c\u306e\u7d44\u7e54\u578b\u3092\u6570\u591a\u304f\u898b\u3066\u3044\u308b\u8a33\u3067\u306f\u3042\u308a\u307e\u305b\u3093\u3002\u73fe\u5b9f\u306b\u306f\u60a3\u5150\u304c\u6765\u308b\u305f\u3073\u306b\u75c5\u540d\u304c\u5909\u308f\u308a\u307e\u3059\u3002\u4f8b\u3048\u3070\u4e4f\u7a81\u8d77\u81a0\u816b\u306e\u60a3\u5150\u306e\u6b21\u306f\u661f\u7d30\u80de\u816b\uff0c\u305d\u306e\u5f8c\u306b\u795e\u7d4c\u7bc0\u81a0\u816b\u306a\u3069\u3068\u3044\u3063\u305f\u5177\u5408\u3067\u3059\u3002\u3053\u308c\u3089\u306e<a title=\"\u30b0\u30ea\u30aa\u30fc\u30de glioma \u795e\u7d4c\u81a0\u816b\" href=\"\/sawamura\/braintumors\/glioma\/sum\/\">\u795e\u7d4c\u81a0\u816b\uff08\u30b0\u30ea\u30aa\u30fc\u30de\uff09<\/a>\u3068\u547c\u3070\u308c\u308b\u816b\u760d\u306f\uff0c\u75c7\u5019\u6027\u3066\u3093\u304b\u3093\u306a\u3069\u3068\u3066\u3082\u3088\u304f\u4f3c\u305f\u75c7\u72b6\u3067\u767a\u75c7\u3057\u3066\uff0cMRI\u753b\u50cf\u6240\u898b\u3082\u3068\u3066\u3082\u4f3c\u3066\u3044\u307e\u3059\u304c\u3001\u305d\u308c\u305e\u308c\u306e\u6cbb\u7642\u6cd5\u306f\u7570\u306a\u3063\u3066\u3044\u308b\u306e\u3067\uff0c\u521d\u8a3a\u6642\u306e\u753b\u50cf\u6240\u898b\u3092\u307f\u8aa4\u308c\u3070\uff0c\u6cbb\u7642\u8a08\u753b\u5168\u4f53\u306b\u3042\u3084\u307e\u308a\u3092\u751f\u3058\u3066\u6cbb\u3059\u6a5f\u4f1a\u3092\u5931\u3063\u3066\u3057\u307e\u3046\u3053\u3068\u3082\u3042\u308a\u307e\u3059\u3002<\/p>\n<p>\u624b\u8853\u3092\u3059\u308b\u304b\u3069\u3046\u304b\u3092\u542b\u3081\u3066\u3001\u306f\u3058\u3081\u3066\u6cbb\u7642\u3092\u6c7a\u3081\u308b\u3068\u304d\u306e\u521d\u671f\u5224\u65ad\u304c\u6700\u7d42\u7684\u306a\u4e88\u5f8c\u3092\u6c7a\u3081\u3066\u3057\u307e\u3046\u3068\u3044\u3063\u3066\u3082\u8a00\u3044\u904e\u304e\u3067\u306f\u3042\u308a\u307e\u305b\u3093\u3002\u3082\u3046\u4e00\u3064<strong><span style=\"color: #333399;\">\u6c7a\u5b9a\u7684\u306b\u91cd\u8981\u306a\u8a3a\u65ad\u306f\u75c5\u7406\u8a3a\u65ad<\/span><\/strong>\u3067\u3059\u3002\u3057\u304b\u3057\uff0c\u7d4c\u9a13\u3092\u7a4d\u3093\u3060\u75c5\u7406\u8a3a\u65ad\u533b\u3067\u3082\u661f\u7d30\u80de\u816b\u3068\u4e4f\u7a81\u8d77\u81a0\u816b\u306e\u9451\u5225\u306b\u306f\u56f0\u3063\u3066\u3057\u307e\u3046\u3053\u3068\u304c\u3042\u308a\uff0c\u907a\u4f1d\u5b50\u8a3a\u65ad\u304c\u5fc5\u8981\u3067\u3059\u3002\u6642\u306b\u81f4\u547d\u7684\u306a\u8aa4\u8a3a\u304c\u3042\u308a\uff0c\u60b2\u3057\u3044\u3053\u3068\u3067\u3059\u304c\uff0c\u6bdb\u69d8\u7d30\u80de\u6027\u661f\u7d30\u80de\u816b\u306e\u5b50\u4f9b\u305f\u3061\u304c\uff0c\u75c5\u7406\u8aa4\u8a3a\u3067\u81a0\u82bd\u816b\u3084\u4e0a\u8863\u816b\u3068\u3057\u3066\u6cbb\u7642\u3055\u308c\u305f\u3068\u3044\u3046\u4e8b\u5b9f\u3082\u77e5\u3063\u3066\u3044\u307e\u3059\u3002\u8133\u816b\u760d\u306e\u6cbb\u7642\u65b9\u6cd5\u306e\u9078\u629e\u306f\u9650\u308a\u306a\u304f\u8907\u96d1\u306a\u306e\u3067\u3059\u3002<\/p>\n<p><a href=\"\/sawamura\/wp\/wp-content\/uploads\/2012\/04\/medullookhe.jpg\"><img loading=\"lazy\" decoding=\"async\" class=\"alignleft size-medium wp-image-5392\" title=\"medullookhe\" src=\"\/sawamura\/wp\/wp-content\/uploads\/2012\/04\/medullookhe-300x244.jpg\" alt=\"\" width=\"300\" height=\"244\" srcset=\"https:\/\/plaza.umin.ac.jp\/sawamura\/wp\/wp-content\/uploads\/2012\/04\/medullookhe-300x244.jpg 300w, https:\/\/plaza.umin.ac.jp\/sawamura\/wp\/wp-content\/uploads\/2012\/04\/medullookhe.jpg 426w\" sizes=\"auto, (max-width: 300px) 100vw, 300px\" \/><\/a><br \/>\n\u3053\u308c\u306f\u9ac4\u82bd\u816b\u306e\u7d44\u7e54\u50cf\uff08HE\u67d3\u8272\uff09\u306a\u306e\u3067\u3059\u304c\uff0c\u3053\u308c\u3060\u3051\u307f\u3066\u3082\u75c5\u7406\u8a3a\u65ad\u306f\u3064\u304d\u307e\u305b\u3093\u3002\u6700\u8fd1\u306f\uff0c\u907a\u4f1d\u5b50\u8a3a\u65ad\u3067WNT, SHH\u306a\u3069\u3092\u898b\u308b\u3053\u3068\u306b\u306a\u3063\u3066\u3044\u307e\u3059\u304c\uff0c\u305d\u308c\u3082\u5224\u7136\u3068\u3057\u306a\u3044\u3053\u3068\u3082\u591a\u3044\u3067\u3059\u3002\u9ac4\u82bd\u816b\u3067\u306f\u304d\u3064\u3044\u653e\u5c04\u7dda\u6cbb\u7642\u3092\u3057\u306a\u3044\u3067\u6cbb\u308b\u30bf\u30a4\u30d7\u3082\u3042\u308a\u307e\u3059\u3002<\/p>\n<h5>2. \u826f\u6027\u8133\u816b\u760d\u3068\u306f<\/h5>\n<p><span style=\"color: #000080;\"><a style=\"color: #000080;\" title=\"\u4e0a\u8863\u816b\" href=\"\/sawamura\/pediattumor\/ependy\/\">\u4e0a\u8863\u816b<\/a><\/span>\u306e\u6cbb\u308b\u78ba\u7387\u306f60%\u304f\u3089\u3044\u3067\uff0c<a href=\"..\/braintumors\/cranio\/\" target=\"_blank\" rel=\"noopener noreferrer\">\u982d\u84cb\u54bd\u982d\u816b<\/a>\u306f8\u5272\u5f37\u3067\u3059\u3002\u305d\u3093\u306a\u306b\u9ad8\u3044\u306f\u305a\u304c\u3042\u308a\u307e\u305b\u3093\u3002\u3053\u308c\u3089\u306f\u826f\u6027\u816b\u760d\u3068\u3055\u308c\u308b\u3082\u306e\u3067\u3059\u304c\uff0c\u4e0a\u8863\u816b\u3067\u306f\uff14\u5206\u306e1\u304c5\u5e74\u4ee5\u5185\u306b\u6b7b\u4ea1\u3059\u308b\u3053\u3068\u3068\u306a\u308a\u307e\u3059\u3057(&gt;_&lt;)\uff0c\u982d\u84cb\u54bd\u982d\u816b\u306b\u304a\u3044\u3066\u306f\u624b\u8853\u306e\u6570\u30f6\u6708\u304b\u3089\u6570\u5e74\u5f8c\u306e\u518d\u767a\u3084\u518d\u71c3\u3082\u591a\u304f\u3066\uff0c\u4f55\u5ea6\u3082\u624b\u8853\u3092\u53d7\u3051\u305f\u308a\uff0c\u5927\u304d\u306a\u5f8c\u907a\u75c7\u3092\u304b\u304b\u3048\u3066\u306a\u3093\u3069\u304b\u751f\u5b58\u3059\u308b\u5b50\u4f9b\u305f\u3061\u304c\u591a\u3044\u306e\u3067\u3059\u3002<\/p>\n<p>\u982d\u84cb\u54bd\u982d\u816b\u306f\uff0c\u8996\u5e8a\u4e0b\u90e8\u3068\u795e\u7d4c\u4e0b\u5782\u4f53\u3068\u3044\u3046\u8133\u306e\u6df1\u304f\u3066\u91cd\u8981\u306a\u6a5f\u80fd\u3092\u3082\u3064\u3068\u3053\u308d\u306b\u3067\u304d\u3066\uff0c\u305d\u3053\u306b\u304f\u3063\u3064\u3044\u3066\u3044\u308b\u305f\u3081\u306b\uff0c\u719f\u7df4\u3057\u305f\u8133\u795e\u7d4c\u5916\u79d1\u533b\u306b\u3068\u3063\u3066\u3082\u624b\u8853\u304c\u3068\u3066\u3082\u96e3\u3057\u3044\u306e\u3067\uff0c\u7d71\u8a08\u306b\u8f09\u3089\u306a\u3044\u3068\u3053\u308d\u3067\u306e\u624b\u8853\u6b7b\u4ea1\u4f8b\u3082\u5c11\u306a\u304f\u306a\u3044\u3068\u60f3\u50cf\u3055\u308c\u307e\u3059\u3002\u307e\u305f\u982d\u84cb\u54bd\u982d\u816b\u306e\u624b\u8853\u3067\u306f\u3067\u304d\u308b\u9650\u308a\u4e0b\u5782\u4f53\u306e\u6a5f\u80fd\u3092\u5b88\u308b\u3053\u3068\u3092\u8003\u3048\u307e\u3059\u304c\uff0c\u73fe\u5b9f\u306b\u306f\u9593\u8133\u4e0b\u5782\u4f53\u6a5f\u80fd\u4e0d\u5168\u75c7\u3068\u8996\u529b\u8996\u91ce\u969c\u5bb3\u3092\u6b8b\u3057\u3066\u751f\u5b58\u3059\u308b\u4f8b\u304c\u5927\u591a\u6570\u3067\u3059\u3002\u3055\u3089\u306b\u624b\u8853\u3067\u5b8c\u5168\u6458\u51fa\u3067\u304d\u306a\u3044\u3068\u304d\u3001\u3068\u304f\u306b\u5c0f\u3055\u306a\u5b50\u4f9b\u305f\u3061\u306b\u653e\u5c04\u7dda\u6cbb\u7642\u304a\u3053\u306a\u3048\u3070\u7cbe\u795e\u767a\u9054\u9045\u6ede\uff08\u8a8d\u77e5\u6a5f\u80fd\u969c\u5bb3\uff09\u306e\u53ef\u80fd\u6027\u304c\u6b8b\u308a\u307e\u3059\u3002<\/p>\n<p>\u4ed6\u306b\u3082\u826f\u6027\u8133\u816b\u760d\u3068\u3044\u308f\u308c\u308b\u4f8b\u3092\u6319\u3052\u308c\u3070\uff0c\u6d77\u7dbf\u72b6\u8840\u7ba1\u816b\u3084\u795e\u7d4c\u7bc0\u81a0\u816b\u306a\u3069\u304c\u4e2d\u8133\u306b\u767a\u751f\u3057\u3066\u3086\u3063\u304f\u308a\u5927\u304d\u304f\u306a\u3063\u305f\u6642\u306b\u306f\uff0c\u6709\u52b9\u306a\u6cbb\u7642\u6cd5\u306f\u307b\u3068\u3093\u3069\u306a\u304f\u3066\u751f\u304d\u6b8b\u308b\u6a5f\u4f1a\u306f\u5c11\u306a\u3044\u3068\u3044\u3048\u307e\u3059\u3002\u3053\u306e\u3088\u3046\u306b\u75c5\u7406\u7d44\u7e54\u5b66\u7684\u306b\u826f\u6027\u3068\u3044\u308f\u308c\u308b\u8133\u816b\u760d\u3067\u3082\uff0c\u5c11\u306a\u304b\u3089\u305a\u91cd\u7be4\u306a\u5185\u5206\u6ccc\u4e0d\u5168\u3084\u795e\u7d4c\u8131\u843d\u75c7\u72b6\uff08\u5f8c\u907a\u75c7\uff09\u3092\u6b8b\u3057\u307e\u3059\u3057\uff0c\u304b\u3064\u5b50\u4f9b\u305f\u3061\u3092\u6b7b\u306b\u5c0e\u304f\u53ef\u80fd\u6027\u306e\u3042\u308b\u75c5\u6c17\u3067\u3059\u3002\u591a\u304f\u306e\u8133\u816b\u760d\u306b\u304a\u3044\u3066\u6559\u79d1\u66f8\u306b\u66f8\u304b\u308c\u3066\u3044\u308b\u7d44\u7e54\u5b66\u7684\u306a\u826f\u6027\u5ea6\u3068\u3044\u3046\u306e\u306f\u5fc5\u305a\u3057\u3082\u6cbb\u308a\u3084\u3059\u3044\u3068\u3044\u3046\u3053\u3068\u3092\u793a\u3057\u307e\u305b\u3093\u3002\u826f\u6027\u3068\u3044\u3046\u3079\u304d\u751f\u6613\u3057\u3044\u3082\u306e\u306f\u307b\u3068\u3093\u3069\u306a\u3044\u306e\u3067\u3059\u3002<\/p>\n<h5>3. \u816b\u760d\u304c\u3067\u304d\u305f\u5834\u6240\u306b\u3088\u308b\u4e88\u5f8c\u306e\u9055\u3044<\/h5>\n<p><a title=\"\u661f\u7d30\u80de\u7cfb\u816b\u760d\" href=\"\/sawamura\/braintumors\/glioma\/astrocytictumor\/\">\u661f\u7d30\u80de\u816b<\/a>\u00a0(WHO\u30b0\u30ec\u30fc\u30c92)\u5168\u4f53\u306e5\u5e74\u751f\u5b58\u5272\u5408\u306f70%\u3067\u3059\u304c\uff0c\u4e00\u65b9\u3067\uff0c<a href=\"brainstemglioma\/\" target=\"_blank\" rel=\"noopener noreferrer\">\u8133\u5e79\u90e8\u306b\u767a\u751f\u3057\u305f\u7d44\u7e54\u5b66\u7684\u3073\u307e\u3093\u6027\u661f\u7d30\u80de\u816b<\/a>\u00a0(WHO\u30b0\u30ec\u30fc\u30c94\uff0c\u3073\u307e\u3093\u6027\u6a4b\u81a0\u816b\uff09\u306e\u6b7b\u4ea1\u5272\u5408\u306f\u307b\u307c100%\u3067\u3059\u3002\u3053\u306e\u69d8\u306b\u7d44\u7e54\u8a3a\u3067\u3073\u307e\u3093\u6027\u661f\u7d30\u80de\u816b(diffuse astrocytoma)\u3068\u75c5\u7406\u8a3a\u65ad\u3055\u308c\u308b\u816b\u760d\u306f\u3067\u304d\u308b\u5834\u6240\u306b\u3088\u3063\u3066\u751f\u547d\u4e88\u5f8c\u306b\u5927\u304d\u306a\u958b\u304d\u304c\u3042\u308a\u307e\u3059\u3002\u73fe\u5728\u3067\u306f\u3053\u306e\u9055\u3044\u306f\u907a\u4f1d\u5b50\u5909\u7570\u306e\u9055\u3044 (IDH mutant\u3068H3K27M mutant) \u3068\u3044\u3046\u3053\u3068\u304c\u308f\u304b\u3063\u3066\u3044\u307e\u3059\u3002<\/p>\n<p>\u3055\u3089\u306b\u4f8b\u3092\u6319\u3052\u308c\u3070\uff0c\u53f3\u524d\u982d\u8449\u306e\u524d\u306e\u65b9\u306b\u767a\u751f\u3057\u305f\u540c\u3058\u661f\u7d30\u80de\u816b\u30b0\u30ec\u30fc\u30c92\u3067\u3082\uff0c\u985e\u5186\u72b6\u3067\u9650\u5c40\u6027\u306b\u767a\u80b2\u3059\u308b\uff08\u56fa\u307e\u308a\u306b\u306a\u3063\u3066\u3044\u308b\uff09\u3082\u306e\u3068\u30b0\u30ea\u30aa\u30de\u30c8\u30fc\u30b7\u30b9\u306e\u3088\u3046\u306b\u5f37\u3044\u6d78\u6f64\u6027\u683c\uff08\u3057\u307f\u8fbc\u3080\u3088\u3046\u306b\u5e83\u304c\u3063\u3066\u3044\u308b\uff09\u3092\u793a\u3059\u3082\u306e\u3067\u306f\u4e88\u5f8c\u306f\u5927\u304d\u304f\u7570\u306a\u308a\u307e\u3059\u3002\u524d\u8005\u306f\u5b8c\u5168\u624b\u8853\u6458\u51fa\u306e\u307f\u3067\u6cbb\u7652\u3057\u307e\u3059\u304c\uff0c\u5f8c\u8005\u306f\u751f\u691c\u8853\u3068\u653e\u5c04\u7dda\u6cbb\u7642\u3092\u884c\u3063\u3066\u3082\u6cbb\u308b\u3053\u3068\u306f\u307b\u3068\u3093\u3069\u3042\u308a\u307e\u305b\u3093\u3002<\/p>\n<p><span style=\"color: #000080;\"><strong>\u5c0f\u8133<\/strong><\/span>\u306b\u767a\u751f\u3057\u305f\u6bdb\u69d8\u7d30\u80de\u6027\u661f\u7d30\u80de\u816b (\u30b0\u30ec\u30fc\u30c91)\u3068\u661f\u7d30\u80de\u816b (\u30b0\u30ec\u30fc\u30c92)\u3067\u306f\uff0c32%\u306b\u5897\u6b96\u505c\u6b62\uff08\u5927\u304d\u304f\u306a\u3089\u306a\u3044\u3067\u305d\u306e\u307e\u307e\u3044\u308b\u3053\u3068\uff09\u304c14%\u306b\u81ea\u7136\u9000\u7e2e\uff08\u4f55\u3082\u3057\u306a\u3044\u3067\u3082\u816b\u760d\u304c\u5c0f\u3055\u304f\u306a\u308b\uff09\u304c\u751f\u3058\u308b\u3068\u3044\u3046\u5831\u544a\u3082\u3042\u308a\u307e\u3059\u304b\u3089\uff0c\u624b\u8853\u306e\u5f8c\u3067\u53d6\u308a\u6b8b\u3057\u305f\u816b\u760d\u304c\u3042\u3063\u3066\u3082\u4f55\u3082\u3057\u306a\u3044\u3067\u305d\u306e\u307e\u307e\u69d8\u5b50\u3092\u898b\u305f\u65b9\u304c\u3044\u3044\u3053\u3068\u3082\u3042\u308b\u306e\u3067\u3059\u3002\u3053\u308c\u3089\u306e\u9055\u3044\u306f\uff0c\u7d44\u7e54\u5b66\u7684\u306a\u8a3a\u65ad\uff08\u75c5\u540d\uff09\u304c\u540c\u3058\u3067\u3042\u3063\u3066\u3082\uff0c\u767a\u751f\u3057\u305f\u8133\u306e\u5834\u6240\u306b\u3088\u3063\u3066\u305d\u308c\u305e\u308c\u6cbb\u7642\u6cd5\u3092\u5909\u3048\u306a\u3051\u308c\u3070\u306a\u3089\u306a\u3044\u3068\u3044\u3046\u3053\u3068\u3092\u793a\u3057\u3066\u3044\u307e\u3059\u3002<\/p>\n<p>\u6b27\u7c73\u306e1,000\u4f8b\u3092\u8d8a\u3048\u308b\u30e9\u30f3\u30c0\u30e0\u5316\u81e8\u5e8a\u8a66\u9a13\u3067\u306f\uff0c\u6210\u4eba\u306e\u30c6\u30f3\u30c8\u4e0a\u661f\u7d30\u80de\u816b\u3078\u306e\u653e\u5c04\u7dda\u6cbb\u7642\u306e\u6709\u52b9\u6027\uff08\u751f\u5b58\u671f\u9593\u306e\u5ef6\u9577\uff09\u306f\u8a3c\u660e\u3055\u308c\u307e\u305b\u3093\u3067\u3057\u305f\u3002\u5f93\u3063\u3066\u30a8\u30d3\u30c7\u30f3\u30b9\u30fb\u30ec\u30d9\u30eb\uff11\uff08\u79d1\u5b66\u7684\u306b\u3057\u3063\u304b\u308a\u3057\u305f\u4e8b\u5b9f\uff09\u3067\u30c6\u30f3\u30c8\u4e0a\u661f\u7d30\u80de\u816b\u3078\u306e\u653e\u5c04\u7dda\u6cbb\u7642\u306e\u9069\u5fdc\u306f\u3042\u308a\u307e\u305b\u3093\u3002\u816b\u760d\u5b66\u306e\u5e38\u8b58\u3067\u306f\u540c\u3058\u7d44\u7e54\u578b\u3067\u3042\u308c\u3070\u653e\u5c04\u7dda\u6cbb\u7642\u306e\u52b9\u679c\u306f\u540c\u69d8\u3067\u3042\u308b\u306f\u305a\u306a\u306e\u3067\uff0c\u5c0f\u5150\u306e\u661f\u7d30\u80de\u816b\u3078\u653e\u5c04\u7dda\u6cbb\u7642\u3092\u3057\u3066\u3082\u52b9\u304b\u306a\u3044\u3068\u63a8\u5b9a\u3055\u308c\u307e\u3059\u3002\u52a0\u3048\u3066\u9ad8\u3044\u30a8\u30d3\u30c7\u30f3\u30b9\u30fb\u30ec\u30d9\u30eb\u3092\u307f\u308c\u3070\uff0c\u661f\u7d30\u80de\u816b\u30b0\u30ec\u30fc\u30c92\u306b\u6709\u52b9\u306a\u5316\u5b66\u7642\u6cd5\u5264\u306f\u306a\u304f\u3066\uff0c\u7d50\u5c40\uff0c\u4e88\u5f8c\u306b\u6700\u3082\u5927\u304d\u306a\u5f71\u97ff\u3092\u4e0e\u3048\u308b\u56e0\u5b50\u306f\u624b\u8853\u3067\u304d\u3061\u3093\u3068\u53d6\u308c\u305f\u304b\u3069\u3046\u304b\u3068\u3044\u3046\u3053\u3068\u306b\u306a\u308a\u307e\u3059\u3002<\/p>\n<p>\u5f93\u3063\u3066\u30c6\u30f3\u30c8\u4e0a\u661f\u7d30\u80de\u816b\u3067\u7406\u8ad6\u7684\u306b\u52e7\u3081\u3089\u308c\u308b\u3053\u3068\u306f\u5b8c\u5168\u624b\u8853\u6458\u51fa\u306e\u307f\u3067\u3059\u3002\u816b\u760d\u306e\u3067\u304d\u305f\u5834\u6240\u306b\u3088\u3063\u3066\u306e\u307f\u6cbb\u7642\u306e\u9069\u5426\u304c\u6c7a\u307e\u308a\u307e\u3059\u3002\u3067\u3082\u8133\u3068\u3044\u3046\u81d3\u5668\u306f\u3053\u306e\u5358\u7d14\u6027\u3092\u8a31\u3057\u307e\u305b\u3093\uff0c\u8133\u306e\u305f\u3044\u305b\u3064\u306a\u5834\u6240\u3092\u307e\u304d\u3053\u3080\u661f\u7d30\u80de\u816b\u306e\u5b8c\u5168\u6458\u51fa\u3092\u8a08\u753b\u3059\u308b\u3053\u3068\u306f\u3067\u304d\u307e\u305b\u3093\u306e\u3067\uff0c\u591a\u304f\u306e\u661f\u7d30\u80de\u816b\u3067\u306f\u751f\u691c\u8853\u5f8c\u306b\u653e\u5c04\u7dda\u5316\u5b66\u7642\u6cd5\u3092\u7528\u3044\u3066\u6cbb\u7642\u3055\u308c\u307e\u3059\u3002\u3053\u3053\u306b\u306f\u7406\u8ad6\u7684\u306b\u6b63\u3057\u3044\u6cbb\u7642\u3068\u5b9f\u969b\u306e\u6cbb\u7642\u304c\u5168\u7136\u9055\u3046\u3068\u3044\u3046\u3068\u3066\u3082\u5927\u304d\u306a\u77db\u76fe\u304c\u3042\u308a\u307e\u3059\u3002\u3057\u304b\u3057\uff0c\u73fe\u5b9f\u7684\u306b\u81e8\u5e8a\u306e\u5834\u3067\u306f\uff0c\u661f\u7d30\u80de\u816b IDH mutant\u30b0\u30ec\u30fc\u30c92\u306b\u653e\u5c04\u7dda\u5316\u5b66\u7642\u6cd5\u3092\u884c\u3046\u3068\uff0c\u816b\u760d\u304c\u7e2e\u5c0f\u3057\u306610\u5e74\u4ee5\u4e0a\u5909\u5316\u304c\u306a\u3044\u3068\u3044\u3046\u3053\u3068\u3082\u3081\u305a\u3089\u3057\u304f\u306f\u3042\u308a\u307e\u305b\u3093\u3002<\/p>\n<h5>4. 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u3002<\/p>\n<p>\u653e\u5c04\u7dda\u6cbb\u7642\u3070\u304b\u308a\u304c\u5f8c\u907a\u75c7\u3092\u5927\u304d\u304f\u3059\u308b\u8a33\u3067\u306f\u3042\u308a\u307e\u305b\u3093\u3002\u653e\u5c04\u7dda\u6cbb\u7642\u4ee5\u5916\u306e\u6cbb\u7642\u65b9\u6cd5\u3067\u3082\u5c0f\u3055\u306a\u5b50\u4f9b\u305f\u3061\u306f\u969c\u5bb3\u3092\u5f37\u304f\u53d7\u3051\u307e\u3059\u3002\u4f4e\u5e74\u9f62\u5150\u3067\u306e\u30e1\u30bd\u30c8\u30ec\u30ad\u30bb\u30fc\u30c8\u306e\u9ac4\u8154\u5185\u6ce8\u5165\u304c\u8a8d\u77e5\u969c\u5bb3\u3092\u5927\u304d\u304f\u3059\u308b\u3053\u3068\u3082\u77e5\u3089\u308c\u3066\u3044\u3066\uff0c\u3088\u307b\u3069\u306e\u5fc5\u8981\u6027\u304c\u306a\u3051\u308c\u3070\u3053\u306e\u5316\u5b66\u7642\u6cd5\u306f\u4f7f\u7528\u3055\u308c\u308b\u3079\u304d\u3067\u306f\u3042\u308a\u307e\u305b\u3093\u3002\u3067\u3082\u5b9f\u969b\u306b\u306f\uff0c\u9ac4\u82bd\u816b\u3084\u30b8\u30e3\u30fc\u30df\u30ce\u30fc\u30de\u306e\u6cbb\u7642\u3067\u30e1\u30bd\u30c8\u30ec\u30ad\u30bb\u30fc\u30c8\u3092\u4f7f\u3063\u3066\u3044\u308b\u30b0\u30eb\u30fc\u30d7\u3082\u3042\u308a\u307e\u3059\u3002<\/p>\n<p>PNET\u306f\u5927\u8133\u306b\u767a\u751f\u3059\u308b\u306e\u3067\u8a8d\u77e5\u969c\u5bb3\u306f\u5c0f\u8133\u306b\u767a\u751f\u3059\u308b\u9ac4\u82bd\u816b\u3088\u308a\u91cd\u304f\u306a\u308a\u307e\u3059\u3002\u6cbb\u7642\u3092\u53d7\u3051\u3066\u751f\u304d\u5ef6\u3073\u3066\u4f55\u5e74\u3082\u305f\u3063\u3066\u304b\u3089\u8d77\u308b\u5f8c\u907a\u75c7\u3068\u3057\u3066\uff0c\u8133\u8840\u7ba1\u969c\u5bb3\u3068\u4e8c\u6b21\u816b\u760d\u306e\u767a\u751f\u30ea\u30b9\u30af\u306f\uff0c\u3053\u308c\u3082\u4f4e\u5e74\u9f62\u5150\u306e\u65b9\u304c\u660e\u3089\u304b\u306b\u9ad8\u304f\u3066\uff0c\u8133\u816b\u760d\u306e\u5834\u5408\u306b\u304a\u3044\u3066\u306f\u653e\u5c04\u7dda\u6cbb\u7642\u3068\u95a2\u9023\u3059\u308b\u9045\u767a\u6027\u5408\u4f75\u75c7\u3067\u3042\u308b\u3068\u3044\u308f\u308c\u307e\u3059\u3002<\/p>\n<h5>5. 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glioma\uff08\u60aa\u6027\u5ea6\u306e\u4f4e\u3044\u30b0\u30ea\u30aa\u30fc\u30de\uff09\u306e\u6cbb\u7642\u3068\u3044\u3046\u767a\u8868\u3092\u805e\u304f\u3053\u3068\u304c\u3042\u308a\u307e\u3059\u3002\u3042\u308b\u65e5\u672c\u306e\u7814\u7a76\u30b0\u30eb\u30fc\u30d7\u306b\u767b\u9332\u3055\u308c\u305f\u201dlow-grade glioma\u201d\u306b\u4e00\u5b9a\u306e\u5316\u5b66\u7642\u6cd5\u3092\u7528\u3044\u3066\u6cbb\u7642\u3057\u305f\u6210\u7e3e\u306e\u767a\u8868\u306a\u3069\u3067\u3059\u3002\u3067\u3082\uff0c\u3053\u306elow-grade glioma\u3068\u3044\u3046\u547c\u3073\u540d\u306f\u6cbb\u7642\u65b9\u6cd5\u3092\u691c\u8a3c\u3059\u308b\u305f\u3081\u306b\u4e00\u3064\u306b\u62ec\u308b\u3053\u3068\u304c\u3067\u304d\u308b\u8a2d\u5b9a\u6839\u62e0\u306e\u3042\u308b\u5358\u4e00\u5bfe\u8c61\u96c6\u56e3\u3067\u306f\u3042\u308a\u307e\u305b\u3093\uff08\u9055\u3063\u305f\u3082\u306e\u3092\u5341\u8449\u4e00\u7d61\u3052\u306b\u3057\u3066\u7814\u7a76\u3057\u3066\u306f\u3044\u3051\u306a\u3044\u3068\u3044\u3046\u610f\u5473\u3067\u3059\uff09\u3002\u3060\u304b\u3089\uff0c\u3053\u306e\u3088\u3046\u306a\u5b66\u4f1a\u767a\u8868\u306b\u306f\u610f\u5473\u304c\u3042\u308a\u307e\u305b\u3093\u304c\uff0c\u5b66\u4f1a\u3067\u767a\u8868\u3055\u308c\u305f\u6210\u7e3e\u3068\u3044\u3046\u3068\u4e00\u822c\u306e\u4eba\u306b\u306f\u672c\u5f53\u306e\u3053\u3068\u306e\u3088\u3046\u306b\u601d\u3048\u3066\u3057\u307e\u3044\u307e\u3059\u3002<\/p>\n<p>\u9006\u306b\u75c5\u7406\u5b66\u7684\u306b\u60aa\u6027\u5ea6\u306e\u4f4e\u3044\u30b0\u30ea\u30aa\u30fc\u30de\u306e\u6cbb\u7642\u65b9\u91dd\u306f\u500b\u3005\u306e\u60a3\u8005\u3055\u3093\u306b\u304a\u3044\u3066\u5343\u5dee\u4e07\u5225\u3067\u3059\u3002\u30d8\u30c6\u30ed\u306a\u5bfe\u8c61\u96c6\u56e3\u306b\u30d8\u30c6\u30ed\uff08\u500b\u3005\u306b\u304a\u3044\u3066\u306f\u9069\u5207\uff09\u306a\u6cbb\u7642\u3092\u65bd\u3059\u3053\u3068\u3092\u8a31\u5bb9\u3059\u308b\u3053\u3068\u304c\u8a8d\u3081\u3089\u308c\u306a\u3051\u308c\u3070\u306a\u3089\u306a\u3044\u816b\u760d\u306b\uff0c\u7814\u7a76\u30d7\u30ed\u30c8\u30b3\u30fc\u30eb\u306b\u57fa\u3065\u3044\u305f\u6cbb\u7642\u3092\u5b89\u6613\u306b\u8a2d\u5b9a\u3059\u308b\u3053\u3068\u306b\u306f\u5371\u967a\u304c\u3042\u308a\u307e\u3059\u3002\u3053\u308c\u306f\u6cbb\u7642\u65b9\u91dd\u304c\u304d\u3061\u3093\u3068\u7acb\u3066\u3089\u308c\u3066\u3044\u308b\u304b\u3089\u3068\u3044\u3063\u3066\u305d\u306e\u6cbb\u7642\u304c\u6b63\u3057\u3044\u3068\u3044\u3046\u3053\u3068\u3067\u306f\u306a\u304f\u3066\uff0c\u9006\u306b\u4e00\u3064\u306e\u65b9\u91dd\u3067\u304a\u304a\u3056\u3063\u3071\u306b\u307e\u3068\u3081\u3066\u6cbb\u7642\u3057\u3066\u3044\u308b\u304b\u3089\u9593\u9055\u3063\u3066\u3044\u308b\u3068\u3044\u3046\u3053\u3068\u3067\u3059\u3002<\/p>\n<p>\u5c0f\u5150\u8133\u816b\u760d\u6cbb\u7642\u306e\u6700\u7d42\u76ee\u6a19\u306f\u3053\u3069\u3082\u306e\u75c5\u6c17\u3092\u6cbb\u3059\u3053\u3068\u3067\u3059\u3002\u3057\u304b\u3057\uff0c\u52b9\u679c\u7684\u306a\u6cbb\u7642\u306b\u306f\u5c11\u306a\u304b\u3089\u305a\u4ee3\u511f\u304c\u3042\u308a\u307e\u3059\u3002\u3067\u3059\u304b\u3089\uff0c\u52b9\u679c\u7684\u306a\u6cbb\u7642\u3068\u305d\u306e\u6cbb\u7642\u6bd2\u6027\u306e\u9593\u306e\u30d0\u30e9\u30f3\u30b9\u3092\u3068\u3066\u3082\u614e\u91cd\u306b\u53d6\u3089\u306a\u3051\u308c\u3070\u306a\u308a\u307e\u305b\u3093\u3002\u4f8b\u3048\u3070\uff0c\u5927\u91cf\u306e\u5316\u5b66\u7642\u6cd5\u3084\u653e\u5c04\u7dda\u6cbb\u7642\u3042\u308b\u3044\u306f\u7a4d\u6975\u7684\u306a\u5916\u79d1\u6458\u51fa\u304c\uff0c\u9ad8\u3044\u6cbb\u7652\u7387\u3092\u3082\u305f\u3089\u3059\u306e\u3068\u540c\u6642\u306b\uff0c\u91cd\u3044\u5f8c\u907a\u969c\u5bb3\u3092\u6b8b\u3059\u3053\u3068\u304c\u3042\u308a\u307e\u3059\u3002\u9006\u306b\uff0c\u6cbb\u7642\u306e\u6bd2\u6027\uff08\u6709\u5bb3\u4e8b\u8c61\u30fb\u526f\u4f5c\u7528\uff09\u3092\u6700\u4f4e\u9650\u306b\u3057\u3088\u3046\u3068\u3059\u308c\u3070\uff0c\u816b\u760d\u306e\u518d\u767a\u7387\u3092\u9ad8\u3081\u308b\u7d50\u679c\u306b\u3082\u306a\u308b\u306e\u3067\u3059\u3002\u4f8b\u3092\u6319\u3052\u3066\u8a00\u3048\u3070\uff0c\u3053\u3069\u3082\u306e\u9ac4\u82bd\u816b\u306b\u653e\u5c04\u7dda\u6cbb\u7642\u3092\u5168\u304f\u3057\u306a\u3044\u3067\u5927\u91cf\u5316\u5b66\u7642\u6cd5\u3060\u3051\u3067\u6cbb\u305d\u3046\u3068\u3044\u3046\u65b9\u91dd\u3092\uff0c\u3088\u304f\u691c\u8a0e\u3082\u305b\u305a\u306b\u3044\u304d\u306a\u308a\u7acb\u3066\u305f\u3068\u3057\u307e\u3057\u3087\u3046\u3002\u3053\u308c\u306f\u6cbb\u7642\u4e0d\u53ef\u80fd\u306a\u518d\u767a\u3092\u62db\u304f\u78ba\u7387\u3092\u9ad8\u3081\u308b\u53ef\u80fd\u6027\u306e\u3042\u308b\u6311\u6226\u3067\u3059\u3002\u5e83\u7bc4\u56f2\u306a\u8133\u3078\u306e\u653e\u5c04\u7dda\u6cbb\u7642\u304c\u6709\u5bb3\u306a\u306e\u3067\uff0c\u30ac\u30f3\u30de\u30ca\u30a4\u30d5\u3067\u30b8\u30e3\u30fc\u30df\u30ce\u30fc\u30de\u3092\u6d88\u3057\u3066\u3057\u307e\u304a\u3046\u3068\u3044\u3046\u65b9\u91dd\u3092\u7acb\u3066\u305f\u3068\u3057\u307e\u3057\u3087\u3046\u3002\u816b\u760d\u306f\u78ba\u304b\u306b\u4e00\u5ea6\u306f\u6d88\u3048\u308b\u306e\u3067\u3059\u304c\uff0c\u5bb9\u8a8d\u3067\u304d\u306a\u3044\u307b\u3069\u306e\u518d\u767a\u306b\u906d\u9047\u3057\u307e\u3059\u3002\u6cbb\u7642\u6cd5\u306e\u6539\u5584\u306f\u4f55\u5e74\u3082\u304b\u3051\u3066\u3086\u3063\u304f\u308a\u9032\u6b69\u3059\u308b\u306e\u3067\u3059\u304b\u3089\uff0c\u526f\u4f5c\u7528\u3092\u907f\u3051\u308b\u305f\u3081\u3068\u306f\u3044\u3048\uff0c\u601d\u3044\u5207\u3063\u305f\u6311\u6226\u3068\u3044\u3046\u3082\u306e\u306f\u6cbb\u7642\u65b9\u91dd\u306e\u4e2d\u306b\u306f\u542b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style=\"color: #ff0000;\">\u307b\u3068\u3093\u3069\u306e\u816b\u760d\u306e\u6cbb\u7642\u65b9\u91dd\u306f\u5de6\u67a0\u306e\u5c0f\u5150\u8133\u816b\u760d\u30b5\u30d6\u30e1\u30cb\u30e5\u30fc\u306b\u66f8\u3044\u3066\u3042\u308a\u307e\u3059\u304b\u3089\u63a2\u3057\u3066\u4e0b\u3055\u3044<\/span><\/strong><\/p>\n<h5><a href=\"medullo\/\">\u9ac4\u82bd\u816b\uff08\u3053\u3053\u3092\u30af\u30ea\u30c3\u30af\u3057\u3066\u4e0b\u3055\u3044\uff09<\/a><\/h5>\n<h5><a href=\"germ\/\" target=\"_blank\" rel=\"noopener noreferrer\">\u80da\u7d30\u80de\u816b\u760d<\/a><a href=\"germ\/\">\uff08\u3053\u3053\u3092\u30af\u30ea\u30c3\u30af\u3057\u3066\u4e0b\u3055\u3044\uff09<\/a><\/h5>\n<h5><a href=\"pilo\/\">\u4e73\u5e7c\u5150\u306e\u6bdb\u69d8\u7d30\u80de\u6027\u661f\u7d30\u80de\u816b\uff08\u3053\u3053\u3092\u30af\u30ea\u30c3\u30af\u3057\u3066\u4e0b\u3055\u3044\uff09<br \/>\n<\/a><\/h5>\n<h5><a title=\"\u4e0a\u8863\u816b\" href=\"\/sawamura\/pediattumor\/ependy\/\">\u4e0a\u8863\u816b\uff08\u3053\u3053\u3092\u30af\u30ea\u30c3\u30af\u3057\u3066\u4e0b\u3055\u3044\uff09<\/a><\/h5>\n<h5><a href=\"..\/braintumors\/temozolo\/\">\u60aa\u6027\u795e\u7d4c\u81a0\u816b\u3068\u30c6\u30e2\u30be\u30ed\u30de\u30a4\u30c9\uff08\u3053\u3053\u3092\u30af\u30ea\u30c3\u30af\u3057\u3066\u4e0b\u3055\u3044\uff09<\/a><\/h5>\n<h4>\u5c0f\u5150\u79d1\u533b\u3068\u8133\u795e\u7d4c\u5916\u79d1\u533b\u306e\u5f79\u5272<\/h4>\n<p>\u591a\u304f\u306e\u816b\u760d\u578b\u306b\u304a\u3044\u3066\u5916\u79d1\u6458\u51fa\u304c\u4e88\u5f8c\u3092\u6c7a\u5b9a\u3059\u308b\u6700\u3082\u91cd\u8981\u306a\u56e0\u5b50\u3067\u3059\u304b\u3089\uff0c\u7279\u306b\u6cbb\u7642\u521d\u671f\u3067\u306f\u8133\u795e\u7d4c\u5916\u79d1\u533b\u304c\u679c\u305f\u3059\u5f79\u5272\u304c\u6700\u3082\u5927\u304d\u304f\uff0c\u5916\u79d1\u624b\u8853\u306e\u6210\u7e3e\u304c\u4e88\u5f8c\u3092\u5de6\u53f3\u3057\u307e\u3059\u3002\u307e\u305f\u3044\u3046\u307e\u3067\u3082\u306a\u304f\uff0c\u5f93\u6765\u304b\u3089\u9593\u8133\u4e0b\u5782\u4f53\u4e0d\u5168\u306e\u6cbb\u7642\uff0c\u7cbe\u795e\u767a\u9054\u9045\u6ede\u30fb\u8a8d\u77e5\u6a5f\u80fd\u969c\u5bb3\u3084\u75c7\u5019\u6027\u3066\u3093\u304b\u3093\u3078\u306e\u5bfe\u51e6\u306f\u5c0f\u5150\u79d1\u533b\u306b\u4f9d\u5b58\u3057\u3066\u3044\u307e\u3059\u3002\u8fd1\u5e74\u3067\u306f\uff0c\u524d\u8ff0\u306e\u3088\u3046\u306b\u816b\u760d\u578b\u306b\u3088\u3063\u3066\u306f\u5316\u5b66\u7642\u6cd5\u304c\u91cd\u8981\u306a\u5f79\u5272\u3092\u679c\u305f\u3059\u3053\u3068\u304c\u660e\u3089\u304b\u3068\u306a\u3063\u3066\u304d\u3066\u3044\u307e\u3059\u304b\u3089\uff0c\u60aa\u6027\u5ea6\u306e\u9ad8\u3044\u5c0f\u5150\u8133\u816b\u760d\u3067\u306f\u8a3a\u65ad\u6642\u304b\u3089\u306e\u5c0f\u5150\u816b\u760d\u533b\u306e\u95a2\u4e0e\u304c\u91cd\u8981\u3067\u3059\u3002<\/p>\n<p>\u65e5\u672c\u306b\u304a\u3044\u3066\u306e\u5c0f\u5150\u8133\u816b\u760d\u75c7\u4f8b\u306f\u591a\u65bd\u8a2d\u306b\u5206\u6563\u3057\u3066\u3044\u3066\uff0c\u5c0f\u5150\u8133\u816b\u760d\u306e\u6cbb\u7642\u4f53\u5236\u3068\u6c34\u6e96\u306f\u671b\u3080\u3079\u304d\u30ec\u30d9\u30eb\u306b\u306f\u3042\u308a\u307e\u305b\u3093\u3002\u5c0f\u5150\u8133\u816b\u760d\u306e\u6cbb\u7642\u3092\u884c\u3046\u305f\u3081\u306b\u306f\uff0c\u5c0f\u5150\u306e\u4e2d\u67a2\u795e\u7d4c\u7cfb\u306b\u9020\u8a63\u306e\u6df1\u3044\u653e\u5c04\u7dda\u6cbb\u7642\u533b\u3068\u795e\u7d4c\u75c5\u7406\u8a3a\u65ad\u533b\u306e\u5354\u529b\uff0c\u773c\u79d1\u3068\u8033\u9f3b\u79d1\u306e\u5b58\u5728\uff0c\u7a00\u5c11\u75be\u60a3\u6cbb\u7642\u3086\u3048\u306e\u65bd\u8a2d\u5185\u502b\u7406\u59d4\u54e1\u4f1a\u306e\u8a8d\u8a3c\uff0c\u4fdd\u5065\u5be9\u67fb\u3068\u533b\u7642\u8cbb\u5bfe\u7b56\uff0c\u770b\u8b77\u5e2b\u6559\u80b2\uff0c\u8abf\u5264\u306e\u5b89\u5168\u78ba\u4fdd\u3068\u7121\u83cc\u7ba1\u7406\u306e\u305f\u3081\u306e\u8a2d\u5099\uff0c\u591a\u5f69\u306a\u4e88\u5f8c\u306b\u5fdc\u3058\u305f\u30a4\u30f3\u30d5\u30a9\u30fc\u30e0\u30c9\u30fb\u30b3\u30f3\u30bb\u30f3\u30c8\uff0c\u60a3\u8005\u30fb\u5bb6\u65cf\u6559\u80b2\u3068\u7cbe\u795e\u7684\u652f\u63f4\uff0c\u5c0f\u5150\u6162\u6027\u75be\u60a3\u306e\u8fc5\u901f\u306a\u624b\u7d9a\u304d\uff0c\u5bb6\u65cf\u306e\u5bbf\u6cca\u65bd\u8a2d\u65a1\u65cb\uff0c\u9662\u5185\u5b66\u7d1a\u6559\u80b2\uff0c\u75c5\u68df\u5185\u3067\u306e\u60a3\u5150\u3068\u6bcd\u89aa\u306e\u30b9\u30c8\u30ec\u30b9\u89e3\u6d88\u306e\u63f4\u52a9\u306a\u3069\u69d8\u3005\u306a\u5bfe\u5fdc\u3092\u3057\u306a\u3051\u308c\u3070\u306a\u308a\u307e\u305b\u3093\u3002\u3060\u304b\u3089\u5730\u57df\u3054\u3068\u306e\u5c0f\u5150\u8133\u816b\u760d\u6cbb\u7642\u65bd\u8a2d\u306e\u30bb\u30f3\u30bf\u30fc\u5316\u304c\u5f37\u304f\u671b\u307e\u308c\u3066\u3044\u308b\u6642\u4ee3\u3067\u3059\u3002<\/p>\n<p>\u4e0a\u8ff0\u3057\u305f\u3088\u3046\u306b\u5168\u3066\u306e\u5c0f\u5150\u8133\u816b\u760d\u306f\u7a00\u5c11\u816b\u760d\uff08\u6570\u304c\u5c11\u306a\u304f\u3066\u73cd\u3057\u3044\uff09\u3067\u6cbb\u7642\u65b9\u6cd5\u306f\u3044\u3061\u3044\u3061\u7570\u306a\u308b\u3082\u306e\u3067\u3059\u3002\u6cbb\u7642\u9577\u671f\u4e88\u5f8c\u3092\u614e\u91cd\u306b\u8003\u3048\u305f\u4e0a\u3067\u306e\u6210\u7e3e\u5411\u4e0a\u3068\u65e5\u672c\u306b\u304a\u3044\u3066\u306e\u5c0f\u5150\u8133\u816b\u760d\u5b66\u306e\u767a\u5c55\u306e\u305f\u3081\u306b\u306f\uff0c\u4f8b\u5916\u3092\u306a\u304f\u3057\u3066\u5168\u3066\u306e\u75c7\u4f8b\u3092\u767b\u9332\u3057\u3066\u691c\u8a3c\u3059\u308b\u4f53\u5236\u306e\u6574\u5099\u304c\u4e0d\u53ef\u6b20\u306a\u306e\u3060\u3068\u79c1\u306f\u8003\u3048\u3066\u3044\u307e\u3059\u3002\u5c0f\u5150\u304c\u3093\u5b66\u4f1a\u306e\u52aa\u529b\u306f\u3053\u308c\u3092\u76ee\u6307\u3057\u3066\u306f\u3044\u307e\u3059\u304c\uff0c\u6b8b\u5ff5\u306a\u304c\u3089\u8133\u795e\u7d4c\u5916\u79d1\u5b66\u4f1a\u306e\u4e2d\u3067\u306e\u3053\u306e\u554f\u984c\u306e\u8a8d\u8b58\u306f\u3068\u3066\u3082\u4f4e\u3044\u3067\u3059\u3002<\/p>\n<p>\u3042\u308b\u7c73\u56fd\u306e\u5c0f\u5150\u795e\u7d4c\u816b\u760d\u533b(pediatric neuro-oncologist)\u304c\uff0c\u5c0f\u5150\u8133\u816b\u760d\u306e\u6cbb\u7642\u6cd5\u306e\u9078\u629e\u306f\u5e38\u306bcase-to-case decision\u3067\u3042\u308b\u3068\u3044\u3063\u305f\u6f14\u8aac\u3092\u805e\u3044\u305f\u3053\u3068\u304c\u3042\u308a\u307e\u3059\u3002\u3072\u3068\u308a\u3072\u3068\u308a\u306e\u5b50\u4f9b\u3067\u9055\u3046\u6cbb\u7642\u3092\u8003\u3048\u306a\u304f\u3066\u306f\u3044\u3051\u306a\u3044\u3057\uff0c\u307e\u3068\u307e\u3063\u305f\u6cbb\u7642\u65b9\u91dd\u3067\u5358\u7d14\u306b\u6cbb\u7642\u3067\u304d\u308b\u3082\u306e\u3067\u306f\u306a\u3044\u3068\u3044\u3046\u610f\u5473\u3067\u3059\u3002\u6b8b\u5ff5\u306a\u304c\u3089case-to-case decision\u3067\u304d\u308b\u7d4c\u9a13\u304c\u8c4a\u304b\u306a\u5c0f\u5150\u795e\u7d4c\u816b\u760d\u533b\u306f\u65e5\u672c\u306b\u306f\u3044\u307e\u305b\u3093\u3002\u79c1\u81ea\u8eab\u3082\u8133\u795e\u7d4c\u5916\u79d1\u533b\u3068\u3057\u3066\u306e\u5c11\u306a\u3044\u77e5\u8b58\u3068\u7d4c\u9a13\u306e\u4e2d\u3067\u60a3\u5150\u3092\u6cbb\u7642\u3057\u3066\u3044\u308b\u306e\u304c\u65e5\u5e38\u3067\u3059\u3057\uff0c\u65e5\u672c\u3067\u306e\u5c0f\u5150\u795e\u7d4c\u816b\u760d\u533b\u306e\u80b2\u6210\u3092\u6025\u304c\u306a\u3051\u308c\u3070\u306a\u3089\u306a\u3044\u3067\u3057\u3087\u3046\u3002<\/p>\n<h4>\u65b0\u3057\u3044\u5206\u5b50\u6a19\u7684\u6cbb\u7642\u306e\u958b\u767a<\/h4>\n<p>\u907a\u4f1d\u5b50\u8a3a\u65ad\u306e\u767a\u9054\u3067\u5c0f\u5150\u8133\u816b\u760d\u306e\u767a\u751f\u539f\u56e0\u306f\u304b\u306a\u308a\u89e3\u660e\u3055\u308c\u3066\u304d\u307e\u3057\u305f\u3002\u3067\u3082\u9577\u3044\u9593\uff0c\u305d\u308c\u306b\u5bfe\u5fdc\u3057\u305f\u6cbb\u7642\u6cd5\u304c\u898b\u3064\u304b\u308a\u307e\u305b\u3093\u3067\u3057\u305f\u3002\u3057\u304b\u3057\u308f\u305a\u304b\u306a\u304c\u3089\u3082\u767a\u5c55\u306f\u3042\u308a\uff0c<a title=\"\u5c0f\u5150\u8133\u816b\u760d\u3068BRAF\u907a\u4f1d\u5b50\" href=\"https:\/\/plaza.umin.ac.jp\/sawamura\/pediattumor\/braf\/\"><span style=\"color: #000080;\"><strong>BRAF v600 mutation<\/strong><span style=\"color: #333333;\">\u3092\u6709\u3059\u308b\u5c0f\u5150\u30b0\u30ea\u30aa\u30fc\u30de\u306b\u306f\uff0c\u30c0\u30d6\u30e9\u30d5\u30a7\u30cb\u30d6 (Tafinlar) \u3068 \u30c8\u30e9\u30e1\u30c1\u30cb\u30d6 (Mekinist\u306e\u6709\u52b9\u6027\u304c\u78ba\u8a8d\u3055\u308c\u307e\u3057\u305f\u3002<\/span><\/span><\/a>2023\u5e74\u306b\u7c73\u56fdFDA\u304c\u627f\u8a8d\u3057\u4e00\u822c\u7684\u306b\u4f7f\u7528\u3067\u304d\u308b\u3088\u3046\u306b\u306a\u308a\u307e\u3057\u305f\u3002\u591a\u578b\u9ec4\u8272\u661f\u7d30\u80de\u816b PXA\u3084\u795e\u7d4c\u7bc0\u81a0\u816b\uff0c\u6bdb\u69d8\u7d30\u80de\u6027\u661f\u7d30\u80de\u816b\u306a\u3069\u304c\u5bfe\u8c61\u3067\u3059\u3002<\/p>\n<h4>\u307e\u3068\u3081<\/h4>\n<p><a href=\"\/sawamura\/wp\/wp-content\/uploads\/2012\/07\/photos\/sola17.png\"><img loading=\"lazy\" decoding=\"async\" style=\"margin-right: 10px; margin-left: 10px;\" src=\"\/sawamura\/wp\/wp-content\/uploads\/2012\/07\/photos\/sola17.png\" alt=\"\" width=\"205\" height=\"281\" align=\"right\" hspace=\"10\" \/><\/a>\u3000\u8133\u816b\u760d\u306f\u5c0f\u5150\u306b\u767a\u751f\u3059\u308b\u56fa\u5f62\u764c\u306e\u4e2d\u3067\u306f\u6700\u3082\u983b\u5ea6\u304c\u9ad8\u304f\uff0c\u304b\u3064\u6b7b\u4ea1\u7387\u306e\u9ad8\u3044\u75be\u60a3\u3067\u3059\u3002\u8133\u816b\u760d\u306f\u4ed6\u306e\u81d3\u5668\u306e\u816b\u760d\u3068\u6bd4\u3079\u3066\u75c5\u7406\u7d44\u7e54\u304c\u591a\u5f69\u3067\uff0c\u5168\u3066\u306e\u8133\u816b\u760d\u306f\u7a00\u5c11\u75be\u60a3\uff08\u3068\u3066\u3082\u307e\u308c\u306a\u75c5\u6c17\uff09\u3068\u3044\u3048\u307e\u3059\u3002\u3055\u3089\u306b\u75c5\u7406\u7d44\u7e54\u8a3a\u65ad\u304c\u540c\u3058\u3067\u3042\u3063\u3066\u3082\u767a\u751f\u3059\u308b\u90e8\u4f4d\u3068\u60a3\u8005\u3055\u3093\u306e\u5e74\u9f62\u306b\u3088\u3063\u3066\u4e88\u5f8c\u304c\u5909\u308f\u308b\u305f\u3081\u306b\u6cbb\u7642\u6cd5\u306e\u9078\u629e\u304c\u8907\u96d1\u306b\u306a\u308a\u307e\u3059\u3002\u4f4e\u5e74\u9f62\u5150\u306e\u8133\u306f\u653e\u5c04\u7dda\u6cbb\u7642\u3067\u3068\u3066\u3082\u969c\u5bb3\u3092\u53d7\u3051\u3084\u3059\u3044\u306e\u3067\uff0c\u5316\u5b66\u7642\u6cd5\u304c\u91cd\u8981\u306a\u6cbb\u7642\u624b\u6bb5\u3068\u306a\u3063\u3066\u3044\u307e\u3059\u3002\u9ac4\u82bd\u816b\u3084\u80da\u7d30\u80de\u816b\u760d\u306a\u3069\u306e\u60aa\u6027\u816b\u760d\u3067\u306f\u8133\u795e\u7d4c\u5916\u79d1\u533b\u3068\u5c0f\u5150\u79d1\u533b\u306e\u5354\u529b\u304c\u6b20\u304b\u305b\u307e\u305b\u3093\u3002<\/p>\n<p><a href=\"\/sawamura\/wp\/wp-content\/uploads\/2012\/04\/yokuyoku.jpg\"><img loading=\"lazy\" decoding=\"async\" class=\"alignleft size-medium wp-image-10311\" src=\"\/sawamura\/wp\/wp-content\/uploads\/2012\/04\/yokuyoku-202x300.jpg\" alt=\"\" width=\"202\" height=\"300\" srcset=\"https:\/\/plaza.umin.ac.jp\/sawamura\/wp\/wp-content\/uploads\/2012\/04\/yokuyoku-202x300.jpg 202w, https:\/\/plaza.umin.ac.jp\/sawamura\/wp\/wp-content\/uploads\/2012\/04\/yokuyoku-404x600.jpg 404w, https:\/\/plaza.umin.ac.jp\/sawamura\/wp\/wp-content\/uploads\/2012\/04\/yokuyoku.jpg 630w\" sizes=\"auto, (max-width: 202px) 100vw, 202px\" \/><\/a><br \/>\n\u73fe\u5728\u65e5\u672c\u3067\u306f\u5c0f\u5150\u8133\u816b\u760d\u306e\u75c7\u4f8b\u306f\u305f\u304f\u3055\u3093\u306e\u65bd\u8a2d\u306b\u5206\u6563\u3057\u3066\u3044\u3066\uff0c\u5168\u3066\u306e\u5b50\u4f9b\u305f\u3061\u306b\u9ad8\u3044\u6c34\u6e96\u306e\u6cbb\u7642\u304c\u3067\u304d\u3066\u3044\u306a\u3044\u3053\u3068\u3082\u3042\u308a\uff0c\u5730\u57df\u3054\u3068\u306e\u6cbb\u7642\u30bb\u30f3\u30bf\u30fc\u3092\u78ba\u7acb\u3059\u308b\u3053\u3068\u304c\u671b\u307e\u308c\u3066\u3044\u307e\u3059\u3002\u307e\u305f\uff0c\u8907\u96d1\u306a\u6cbb\u7642\u6cd5\u306e\u9078\u629e\u306f\u5e38\u306bcase-to-case decision\uff08\u500b\u3005\u306e\u60a3\u8005\u3067\u9010\u4e00\u7570\u306a\u308b\u3053\u3068\uff09\u3067\u3042\u308a\uff0c\u6df1\u304f\u3066\u30ec\u30d9\u30eb\u306e\u9ad8\u3044\u77e5\u8b58\u3092\u3082\u3061\u7d4c\u9a13\u8c4a\u304b\u306a\u5c0f\u5150\u795e\u7d4c\u816b\u760d\u533b\u306e\u80b2\u6210\u304c\u6c42\u3081\u3089\u308c\u3066\u3044\u307e\u3059 \u3002<\/p>\n<h5>\u96d1\u591a\u306a\u77e5\u8b58<\/h5>\n<\/div>\n<h4 data-test=\"article-title\">2020\u5e74\u306e\u6bb5\u968e\u3067\uff0c\u5c0f\u5150\u8133\u816b\u760d\u306e\u5168\u3066\u306e\u907a\u4f1d\u5b50\u3092\u8abf\u3079\u305f\u3089\u5229\u76ca\u304c\u3042\u308b\u306e\u304b\uff1f<\/h4>\n<p class=\"c-article-title\" data-test=\"article-title\">Wong M: Whole genome, transcriptome and methylome profiling enhances actionable target discovery in high-risk pediatric cancer. Nat Med 2020<br \/>\n\u5168\u3066\u306e\u816b\u760d\u3068\u751f\u6b96\u7cfb\u5217\u30b2\u30ce\u30e0\uff0cRNA\u304c\u30b7\u30fc\u30af\u30a8\u30f3\u30b9\u306b\u304b\u3051\u3089\u308c\u307e\u3057\u305f\u3002\u8981\u3059\u308b\u306b\u816b\u760d\u306b\u95a2\u3057\u3066\u5168\u3066\u306e\u907a\u4f1d\u5b50\u5909\u7570\u304c\u8abf\u3079\u3089\u308c\u305f\u3068\u3044\u3046\u3053\u3068\u3067\u3059\u300276\u4f8b\u306e\u4e2d\u67a2\u795e\u7d4c\u816b\u760d\u3067DNA\u30e1\u30c1\u30eb\u5316\u3092\u8abf\u3079\u3066\u898b\u305f\u3068\u3053\u308d\uff0c71%\u3067\u8a3a\u65ad\u304c\u78ba\u5b9a\u3067\u304d\uff0c2.6%\uff082\u4f8b\uff09\u3067\u8a3a\u65ad\u304c\u5909\u308f\u308a\u307e\u3057\u305f\u3002\u3068\u3044\u3046\u304f\u3089\u3044\u306e\u6210\u679c\u304c\u5f97\u3089\u308c\u305f\u305d\u3046\u3067\u3059\u3002\u907a\u4f1d\u5b50\u691c\u67fb\u304c\u5c0f\u5150\u8133\u816b\u760d\u306e\u6cbb\u7642\u306e\u6210\u679c\u3092\u5411\u4e0a\u3055\u305b\u308b\u306b\u306f\uff0c\u307e\u3060\u307e\u3060\u9060\u3044\u9053\u306e\u308a\u304c\u3042\u308a\u305d\u3046\u3067\u3059\u3002<\/p>\n","protected":false},"excerpt":{"rendered":"<p>\u5c0f\u5150\u8133\u816b\u760d\u306e\u30b8\u30ec\u30f3\u30de \u81ea\u5206\u306e\u5b50\u3069\u3082\u304c\u8133\u816b\u760d\u3060\u3068\u544a\u3052\u3089\u308c\u308b\u3068\uff0c\u89aa\u306f\u52d5\u63fa\u3057\u307e\u3059\u3002\u3000\u3069\u3046\u3057\u305f\u3089\u547d\u3092\u52a9\u3051\u3089\u308c\u308b\u3093\u3060\u308d\u3046\u304b\uff1f\u3000\u8a3a\u3066\u304f\u308c\u3066\u3044\u308b\u304a\u533b\u8005\u3055\u3093\u306f\uff0c\u3053\u306e\u75c5\u6c17\u306b\u8a73\u3057\u3044\u306e\u3060\u308d\u3046\u304b\uff1f\u3000\u4fe1\u7528\u3067\u304d\u308b\u3093\u3060\u308d\u3046\u304b\uff1f\u3000\u3069\u3053\u306e\u75c5\u9662\u306b\u884c\u3063\u305f\u3089\u3044 [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[5],"tags":[],"class_list":["post-162","post","type-post","status-publish","format-standard","hentry","category-pediattumor"],"aioseo_notices":[],"_links":{"self":[{"href":"https:\/\/plaza.umin.ac.jp\/sawamura\/wp-json\/wp\/v2\/posts\/162","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/plaza.umin.ac.jp\/sawamura\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/plaza.umin.ac.jp\/sawamura\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/plaza.umin.ac.jp\/sawamura\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/plaza.umin.ac.jp\/sawamura\/wp-json\/wp\/v2\/comments?post=162"}],"version-history":[{"count":60,"href":"https:\/\/plaza.umin.ac.jp\/sawamura\/wp-json\/wp\/v2\/posts\/162\/revisions"}],"predecessor-version":[{"id":22594,"href":"https:\/\/plaza.umin.ac.jp\/sawamura\/wp-json\/wp\/v2\/posts\/162\/revisions\/22594"}],"wp:attachment":[{"href":"https:\/\/plaza.umin.ac.jp\/sawamura\/wp-json\/wp\/v2\/media?parent=162"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/plaza.umin.ac.jp\/sawamura\/wp-json\/wp\/v2\/categories?post=162"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/plaza.umin.ac.jp\/sawamura\/wp-json\/wp\/v2\/tags?post=162"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}