{"id":4927,"date":"2014-04-21T13:25:21","date_gmt":"2014-04-21T04:25:21","guid":{"rendered":"\/sawamura\/blog\/?p=4927"},"modified":"2024-07-30T11:39:17","modified_gmt":"2024-07-30T02:39:17","slug":"novottf","status":"publish","type":"post","link":"https:\/\/plaza.umin.ac.jp\/sawamura\/blog\/glioma\/novottf\/","title":{"rendered":"Novo TTF  tumor treating fields, \u30aa\u30d7\u30c1\u30e5\u30fc\u30f3"},"content":{"rendered":"<ul>\n<li><span style=\"color: #ff0000;\"><strong>TTF tumor treating fields<\/strong><\/span>\u3068\u3044\u3046\u540d\u524d\u306e\u6cbb\u7642\u6cd5\u3067\u3059<\/li>\n<li>\u6b63\u5f0f\u306b\u306f\u300c\u4ea4\u6d41\u96fb\u5834\u816b\u760d\u6cbb\u7642\u30b7\u30b9\u30c6\u30e0\u300d\u3068\u8a33\u304c\u6c7a\u307e\u308a\u307e\u3057\u305f<\/li>\n<li>2017\u5e74\u306b\uff0c\u521d\u767a\u81a0\u82bd\u816b\u751f\u5b58\u671f\u9593\u4e2d\u592e\u5024\u30924 &#8211; 5\u30f6\u6708\u307b\u3069\u5ef6\u9577\u3059\u308b\u3068\u6700\u7d42\u5831\u544a\u304c\u3042\u308a\u307e\u3057\u305f<\/li>\n<li><span style=\"color: #000080;\"><strong>2018\u5e74\u304b\u3089\uff0c\u521d\u767a\u81a0\u82bd\u816b\u306b\u4fdd\u967a\u8a3a\u7642<\/strong><span style=\"color: #333333;\">\u304c\u307f\u3068\u3081\u3089\u308c\u305f<\/span><\/span>\u88c5\u7f6e\u3067\u3059<\/li>\n<li>\u982d\u76ae\u306e\u4e0a\u306e\u96fb\u6975\u30d1\u30c3\u30c9 (transducer arrays) \u304b\u3089\uff0c\u8133\u816b\u760d\u306b\u5411\u3051\u3066\uff0c\u975e\u5e38\u306b<span style=\"color: #000080;\"><strong>\u5f31\u3044\u4e2d\u9593\u5468\u6ce2(200kHz) \u306e\u4ea4\u6d41\u96fb\u5834<\/strong><\/span>\u3092\u6301\u7d9a\u7684\u306b\u767a\u751f\u3055\u305b\u3066\uff0c<span style=\"color: #ff0000;\"><strong>\u8133\u816b\u760d\u7d30\u80de\u306e\u5206\u88c2\u3092\u963b\u5bb3\u3057\u307e\u3059<\/strong><\/span><\/li>\n<li>\u982d\u9aea\u3092\u5243\u3063\u3066\u4e38\u574a\u4e3b\u306b\u3057\u3066\uff0c\u982d\u76ae\u306b\u30d1\u30c3\u30c9\u3092\u8cbc\u308a\u4ed8\u3051\u3066\uff0c\u5e3d\u5b50\u306e\u3088\u3046\u306a\u3082\u306e\u3092\u305a\u30fc\u3063\u3068\u88ab\u3063\u3066\u3044\u308b\u3068\u3044\u3046\u6cbb\u7642\u3067\u3059<\/li>\n<\/ul>\n<p><img loading=\"lazy\" decoding=\"async\" class=\"aligncenter size-large wp-image-13924\" src=\"https:\/\/plaza.umin.ac.jp\/sawamura\/blog\/wp-content\/uploads\/2014\/04\/array-550x367.jpg\" alt=\"\" width=\"550\" height=\"367\" srcset=\"https:\/\/plaza.umin.ac.jp\/sawamura\/blog\/wp-content\/uploads\/2014\/04\/array-550x367.jpg 550w, https:\/\/plaza.umin.ac.jp\/sawamura\/blog\/wp-content\/uploads\/2014\/04\/array-300x200.jpg 300w, https:\/\/plaza.umin.ac.jp\/sawamura\/blog\/wp-content\/uploads\/2014\/04\/array-768x512.jpg 768w\" sizes=\"auto, (max-width: 550px) 100vw, 550px\" \/><\/p>\n<p>\u30d1\u30c3\u30c9\u3092\u8cbc\u308a\u4ed8\u3051\u3066\u3044\u308b\u3068\u3053\u308d\u3067\u3059\uff08NOVOCURE\u793e\u3088\u308a\u63d0\u4f9b\uff09<a href=\"https:\/\/plaza.umin.ac.jp\/sawamura\/blog\/wp-content\/uploads\/2014\/04\/novottf1-1.jpg\"><img loading=\"lazy\" decoding=\"async\" class=\"alignnone size-large wp-image-22015\" src=\"https:\/\/plaza.umin.ac.jp\/sawamura\/blog\/wp-content\/uploads\/2014\/04\/novottf1-1-550x450.jpg\" alt=\"\" width=\"550\" height=\"450\" srcset=\"https:\/\/plaza.umin.ac.jp\/sawamura\/blog\/wp-content\/uploads\/2014\/04\/novottf1-1-550x450.jpg 550w, https:\/\/plaza.umin.ac.jp\/sawamura\/blog\/wp-content\/uploads\/2014\/04\/novottf1-1-300x245.jpg 300w, https:\/\/plaza.umin.ac.jp\/sawamura\/blog\/wp-content\/uploads\/2014\/04\/novottf1-1-768x628.jpg 768w, https:\/\/plaza.umin.ac.jp\/sawamura\/blog\/wp-content\/uploads\/2014\/04\/novottf1-1.jpg 787w\" sizes=\"auto, (max-width: 550px) 100vw, 550px\" \/><\/a><\/p>\n<ul>\n<li>\u82f1\u8a9e\u3067\u3059\u3068\uff0clow-intensity, intermediate frequency electric fields via non-invasive, transducer arrays<\/li>\n<\/ul>\n<ul>\n<li><strong><span style=\"color: #000080;\">\u30aa\u30d7\u30c1\u30e5\u30fc\u30f3<\/span><\/strong> NovoTTF-100A \u3068\u3044\u3046\u306e\u306f\u6cbb\u7642\u88c5\u7f6e\u306e\u5546\u54c1\u540d\u3067\uff0c1.2kg\u304f\u3089\u3044\u306e\u91cd\u3055\u3067\u6301\u3061\u904b\u3073\u3067\u304d\u307e\u3059<\/li>\n<li>\u60aa\u6027\u816b\u760d\u306e\u7d30\u80de\u306f\u5897\u3048\u308b\u6642\u306b\uff0c\u7d30\u80de\u5206\u88c2\u3092\u3057\u30662\u3064\u306b\u5206\u304b\u308c\u308b\u306e\u3067\u3059\u304c\uff0c<span style=\"color: #333333;\">\u305d\u306e\u5206\u88c2\u3092\u5f31\u3044\u96fb\u5834\u3067\u59a8\u3052\u308b\u3082\u306e\u3067\u3059 (antimitotic treatment)<\/span><\/li>\n<li>\u305d\u306e\u7d50\u679c\uff0c\u816b\u760d\u7d30\u80de\u304c\u5897\u3048\u308b\u3053\u3068\u304c\u3067\u304d\u307e\u305b\u3093<\/li>\n<li>\u7406\u8ad6\u7684\u306b\u306f\uff0c<strong><span style=\"color: #ff0000;\">\u81a0\u82bd\u816b\u304c\u5927\u304d\u304f\u306a\u308b\u3053\u3068\u306f\u3042\u308b\u7a0b\u5ea6\u9632\u3052\u308b<\/span><\/strong>\u306e\u3067\u3059\u304c\uff0c\u816b\u760d\u3092\u5c0f\u3055\u304f\u3059\u308b\u3053\u3068\u306f\u96e3\u3057\u3044\u3067\u3059<\/li>\n<li><span style=\"color: #000080;\"><strong>\u816b\u760d\u3092\u300c\u6cbb\u3059\u300d\u88c5\u7f6e\u3067\u306f\u3042\u308a\u307e\u305b\u3093<\/strong><\/span><\/li>\n<li>\u88c5\u7740\u306e\u305f\u3081\u306b\u982d\u306e\u6bdb\u3092\u5243\u308b\u5fc5\u8981\u304c\u3042\u308a\uff0c\u5e38\u6642\u306e\u6301\u3061\u904b\u3073\uff081\u65e518\u6642\u9593\u4ee5\u4e0a\uff09\u304c\u65e5\u5e38\u751f\u6d3b\u3092\u5236\u9650\u3057\u307e\u3059<\/li>\n<li>\u88c5\u7740\u6642\u9593\u304c\u9577\u3044\u307b\u3069\u52b9\u679c\u306f\u9ad8\u307e\u308b\u3082\u306e\u3067\u3059<\/li>\n<li>\u96fb\u5834\u306b\u30e0\u30e9\u304c\u3042\u308b\u3068\u6709\u52b9\u6027\u304c\u4f4e\u4e0b\u3059\u308b\u3068\u3055\u308c\u3066\u3044\u307e\u3059\uff0c\u9006\u3082\u771f\u3067\u3059<\/li>\n<li>\u304a\u3082\u306a\u526f\u4f5c\u7528\u306f\uff0c\u982d\u76ae\u306e\u63a5\u89e6\u6027\u76ae\u819a\u708e\u3067\u3059<\/li>\n<li>\u9577\u6642\u9593\u88c5\u7740\u3059\u308b\u3068\u6709\u52b9\u6027\u306f\u9ad8\u307e\u308b\u306e\u3067\u3059\u304c\uff0c\u76ae\u819a\u306e\u30c8\u30e9\u30d6\u30eb\u306f\u5897\u3048\u307e\u3059<\/li>\n<li>\u521d\u767a\u60a3\u8005\u3055\u3093\u3067\u306e\u4f7f\u7528\u671f\u9650\u306e\u5236\u9650\u306f\u3042\u308a\u307e\u305b\u3093\uff0c\u816b\u760d\u518d\u767a\uff08\u518d\u71c3\uff09\u3057\u3066\u3082\u7d99\u7d9a\u3067\u304d\u307e\u3059\u3057\uff0c2\u5e74\u4ee5\u4e0a\u4f7f\u7528\u3057\u3066\u3044\u308b\u60a3\u8005\u3055\u3093\u3082\u3044\u307e\u3059<\/li>\n<li>\u518d\u767a\u304b\u3089\u306e\u4f7f\u7528\u3067\u306f\u4fdd\u967a\u8a3a\u7642\u306f\u3067\u304d\u306a\u304f\u3066\uff0c\u81ea\u8cbb\u3067\u5e74\u9593\u5343\u4e07\u5186\u5358\u4f4d\u306e\u8cbb\u7528\u304c\u304b\u304b\u308a\u307e\u3059<\/li>\n<li><span style=\"color: #000080;\"><strong>\u518d\u767a\u3078\u306e\u4f7f\u7528\u306f\u304a\u52e7\u3081\u3067\u304d\u307e\u305b\u3093<\/strong><\/span><\/li>\n<li>\n<p style=\"text-align: center;\"><img loading=\"lazy\" decoding=\"async\" class=\"aligncenter size-large wp-image-13920\" src=\"https:\/\/plaza.umin.ac.jp\/sawamura\/blog\/wp-content\/uploads\/2014\/04\/SHO7021-TanArrays-550x367.jpg\" alt=\"\" width=\"550\" height=\"367\" srcset=\"https:\/\/plaza.umin.ac.jp\/sawamura\/blog\/wp-content\/uploads\/2014\/04\/SHO7021-TanArrays-550x367.jpg 550w, https:\/\/plaza.umin.ac.jp\/sawamura\/blog\/wp-content\/uploads\/2014\/04\/SHO7021-TanArrays-300x200.jpg 300w, https:\/\/plaza.umin.ac.jp\/sawamura\/blog\/wp-content\/uploads\/2014\/04\/SHO7021-TanArrays-768x513.jpg 768w, https:\/\/plaza.umin.ac.jp\/sawamura\/blog\/wp-content\/uploads\/2014\/04\/SHO7021-TanArrays.jpg 984w\" sizes=\"auto, (max-width: 550px) 100vw, 550px\" \/>\u88c5\u7f6e\u3067\u3059\uff08NOVOCURE\u793e\u3088\u308a\u63d0\u4f9b\uff09<\/p>\n<h5>\u6ce8\u610f\uff1a\u5168\u3066\u306e\u521d\u767a\u81a0\u82bd\u816b\u306e\u60a3\u8005\u3055\u3093\u306b\u5229\u70b9\u304c\u3042\u308b\u308f\u3051\u3067\u306f\u3042\u308a\u307e\u305b\u3093<\/h5>\n<p>\u30aa\u30d7\u30c1\u30e5\u30fc\u30f3\u304c\u6709\u7528\u3060\u3068\u3055\u308c\u308b\u60a3\u8005\u3055\u3093\u306f\uff0c\u958b\u982d\u624b\u8853\u6458\u51fa\u3057\u3066\uff0c\u75c5\u7406\u78ba\u5b9a\u8a3a\u65ad\u304c\u3067\u304d\u3066\uff0c\uff16\u9031\u9593\u306760\u30b0\u30ec\u30a4\u304f\u3089\u3044\u306e30-33\u56de\u306e\u653e\u5c04\u7dda\u6cbb\u7642\u3068\u30c6\u30e2\u30be\u30ed\u30de\u30a4\u30c9\u5316\u5b66\u7642\u6cd5\u3092\u53d7\u3051\u3066\uff0c\u305d\u306e\u5f8c\u306b\u306a\u304a\u304b\u3064\u826f\u3044\u72b6\u614b\u3092\u4fdd\u3063\u3066\u3044\u308b\u60a3\u8005\u3055\u3093\u306b\uff0c\u4f7f\u7528\u3057\u305f\u5834\u5408\u3067\u3059\u3002\u7279\u306b\uff0c\u9ad8\u9f62\u8005\u3067\u77ed\u671f\u9593\u653e\u5c04\u7dda\u6cbb\u7642\u3092\u53d7\u3051\u305f\u60a3\u8005\u3055\u3093\u306a\u3069\u3078\u306e\u6709\u52b9\u6027\u306f\u4e0d\u660e\u3067\u3059\u3002\u8a3a\u65ad\u304b\u3089\u653e\u5c04\u7dda\u6cbb\u7642\u7d42\u4e86\u307e\u3067\u306f\uff0c3-4\u30f6\u6708\u304b\u304b\u308b\u306e\u3067\u3059\u304c\uff0c\u305d\u306e\u9593\u306b\u60aa\u5316\u3057\u3066\u3057\u307e\u3046\u81a0\u82bd\u816b\uff0830%\u4ee5\u4e0a\u3042\u308a\u307e\u3059\uff09\u3092\u9664\u3044\u305f\u5834\u5408\u306b\u306e\u307f\u6709\u7528\u306a\u306e\u304b\u3082\u3057\u308c\u307e\u305b\u3093\u3002<\/p>\n<h5>\u65e5\u672c\u3067\u306e\u5b9f\u7e3e<\/h5>\n<p>2022\u5e743\u6708\u3067\u306f\uff0c330\u4eba\u307b\u3069\u306e\u60a3\u8005\u3055\u3093\u304c\u4f7f\u7528\u3057\u3066\u3044\u307e\u3059<br \/>\n\u7d2f\u8a08\u3067\u306f\u304a\u3088\u305d1,000\u4f8b\u307b\u3069\u3067\u3059\uff0c\u3053\u306e\u6570\u5b57\u306f\u5f90\u3005\u306b\u5897\u52a0\u3057\u3066\u3044\u304d\u307e\u3059<br \/>\n\u4f7f\u7528\u3057\u3066\u3044\u308b\u65bd\u8a2d\u306f\u5168\u56fd\u3067\u304a\u3088\u305d330\u65bd\u8a2d\u304f\u3089\u3044\u3068\u306a\u308a\u307e\u3059<\/p>\n<h5>\u30aa\u30d7\u30c1\u30e5\u30fc\u30f3\u3078\u306e\u6279\u5224<\/h5>\n<p>Wick W: TTFields:\u00a0where\u00a0does all the\u00a0skepticism\u00a0come\u00a0from? Neuro Oncol\u00a02016<br \/>\n\u8133\u816b\u760d\u5b66\u306e\u5c02\u9580\u5bb6\u304b\u3089\u306f\uff0cEF-14\u306e\u81e8\u5e8a\u8a66\u9a13\u304c315\u4f8b\u306e\u4e2d\u9593\u89e3\u6790\u3067\u30e9\u30f3\u30c0\u30e0\u5316\u4e2d\u65ad\u3055\u308c\u305f\u3053\u3068\u306b\u304b\u306a\u308a\u5f37\u3044\u6279\u5224\u304c\u3042\u308a\u307e\u3059\u30022019\u5e74\u6642\u70b9\u3067\uff0c\u30aa\u30d7\u30c1\u30e5\u30fc\u30f3\u306f\u6a19\u6e96\u6cbb\u7642 the standard of care\u3068\u306f\u8a00\u3048\u307e\u305b\u3093\u3002\u6a19\u6e96\u6cbb\u7642\u3068\u3044\u3046\u306e\u306f\u591a\u304f\u306e\u8133\u816b\u760d\u5c02\u9580\u5bb6\u306b\u3088\u3063\u3066\u4e16\u754c\u7684\u306b\u5e83\u304f\u6c4e\u7528\u3055\u308c\u3066\u3044\u308b\u6cbb\u7642\u6cd5\u3067\u3059\u3002\u3057\u304b\u3057\uff0c<span style=\"color: #000080;\"><strong>\u30aa\u30d7\u30c1\u30e5\u30fc\u30f3\u306e\u5229\u7528\u7387\u306f\u9ad8\u3044\u3068\u306f\u8a00<\/strong><\/span><span style=\"color: #000080;\"><strong>\u3048\u307e\u305b\u3093<\/strong><\/span>\u3002<\/p>\n<h5>\u306a\u305c\u3042\u307e\u308a\u5e83\u307e\u3089\u306a\u3044\u306e\u304b<\/h5>\n<p>\u30aa\u30d7\u30c1\u30e5\u30fc\u30f3\u3092\u88c5\u7740\u3067\u304d\u308b\u306e\u306f\uff0c\u521d\u767a\u81a0\u82bd\u816b\u306e\u4e2d\u3067\u3082\u6bd4\u8f03\u7684\u306b\u826f\u3044\u7d4c\u904e\u3092\u305f\u3069\u308b\u60a3\u8005\u3055\u3093\u3067\u3059\u3002\u751f\u5b58\u671f\u9593\u3092\u4e2d\u592e\u5024\u30674\u22125\u30f6\u6708\u5ef6\u9577\u3067\u304d\u308b\u53ef\u80fd\u6027\u306f\u3042\u308b\u306e\u3067\u3059\u304c\uff0c\u982d\u9aea\u3092\u5243\u3063\u3066\u6bce\u65e5\u307b\u3068\u3093\u3069\u306e\u6642\u9593\uff0c\u88c5\u7f6e\u3092\u3064\u3051\u306a\u3051\u308c\u3070\u306a\u308a\u307e\u305b\u3093\u3002\u76ee\u7acb\u3064\u88c5\u7f6e\u3067\u3059\u3057\u4e00\u65e5\u4e2d\u6c17\u306b\u304b\u304b\u308a\u307e\u3059\u3002\u3082\u3068\u3082\u3068\u4e88\u5f8c\u304c\u60aa\u3044\u81a0\u82bd\u816b\u306e\u60a3\u8005\u3055\u3093\u3067\uff0c\u6b8b\u3055\u308c\u305f\u6642\u9593\u306b\u304a\u3044\u3066\u306e\u5fc3\u7406\u7684\u306a\u8ca0\u62c5\u306f\u304b\u306a\u308a\u5927\u304d\u306a\u3082\u306e\u306a\u306e\u3067\u3059\u3002<\/p>\n<h5>\u30c6\u30e2\u30be\u30ed\u30de\u30a4\u30c9\u3068\u6bd4\u8f03\u3057\u3066\u306e\u5229\u70b9<\/h5>\n<p>\u30c6\u30e2\u30be\u30ed\u30de\u30a4\u30c9 TMZ\u306f\uff0c\u81a0\u82bd\u816b\u306eMGMT\u30e1\u30c1\u30ec\u30fc\u30b7\u30e7\u30f3\u306e\u6709\u7121\u3067\u52b9\u679c\u304c\u5927\u304d\u304f\u7570\u306a\u308b\u3053\u3068\u304c\u77e5\u3089\u308c\u3066\u3044\u307e\u3059\u3002\u3057\u304b\u3057\uff0c\u30aa\u30d7\u30c1\u30e5\u30fc\u30f3\u306f\uff0c\u539f\u5247\u7684\u306b\u5897\u6b96\u80fd\u529b\u306e\u9ad8\u3044\u60aa\u6027\u816b\u760d\u3067\u3042\u308c\u3070\u6709\u52b9\u3067\u3042\u308d\u3046\u3068\u3044\u3046\u3053\u3068\u304c\u3042\u308a\u307e\u3059\u3002<\/li>\n<\/ul>\n<h5>2017\u5e7412\u6708 NCCN\u306e\u30ac\u30a4\u30c9\u30e9\u30a4\u30f3\uff1a\u30ab\u30c6\u30b4\u30ea\u30fc\uff11<\/h5>\n<p><span style=\"color: #000080;\"><strong>\u7c73\u56fd\u306eNCCN\u304c\u81a0\u82bd\u816b\u306e\u6a19\u6e96\u6cbb\u7642<\/strong><\/span>\u3068\u3057\u3066\uff0c\u65b0\u305f\u306a\u81e8\u5e8a\u8a66\u9a13\u3078\u306e\u53c2\u52a0\uff0c\u653e\u5c04\u7dda\u3068\u30c6\u30e2\u30be\u30ed\u30de\u30a4\u30c9\uff0c\u653e\u5c04\u7dda\u3068\u30c6\u30e2\u30be\u30ed\u30de\u30a4\u30c9\u306b\u30aa\u30d7\u30c1\u30e5\u30fc\u30f3\u3092\u52a0\u3048\u308b\u6cbb\u7642\u6cd5\u3092\u540c\u5217\u306b\u6271\u3046\u3068\u3057\u307e\u3057\u305f\u3002<\/p>\n<h5>2017\u5e74 EF-14\u306e\u6700\u7d42\u5831\u544a<\/h5>\n<p>Stop R, et al.:\u00a0Effect\u00a0of\u00a0Tumor-Treating\u00a0Fields\u00a0Plus\u00a0Maintenance\u00a0Temozolomide vs\u00a0Maintenance\u00a0Temozolomide Alone on Survival in Patients With Glioblastoma: A Randomized Clinical Trial. JAMA 2017<br \/>\n695\u4f8b\u306e\u89e3\u6790\u5831\u544a\u3067\u3059\u3002\u30c6\u30e2\u30be\u30ed\u30de\u30a4\u30c9\u306e\u307f\u3067\u306f2\u5e74\u751f\u5b58\u5272\u5408\u306f30%\uff0c\u30aa\u30d7\u30c1\u30e5\u30fc\u30f3\u306e\u4f75\u7528\u3067\u306f43%\u3067\u3057\u305f\u30025\u5e74\u751f\u5b58\u5272\u5408\u306f\u305d\u308c\u305e\u308c5%\u306813%\u3067\u3057\u305f\u3002\u5168\u751f\u5b58\u671f\u9593\u4e2d\u592e\u5024\u306f\uff0c\u305d\u308c\u305e\u308c16\u30f6\u6708\u306821\u30f6\u6708\u3067\u3059\u3002<\/p>\n<h5>2017\u5e7411\u6708SNO\u3067\u306e\u5831\u544a<\/h5>\n<p>EF-14\u306e\u8ffd\u52a0\u89e3\u6790\u3067\u3059\u3002\u30aa\u30d7\u30c1\u30e5\u30fc\u30f3\u30921\u65e5\u306e\u3046\u3061\u306e\u3069\u306e\u304f\u3089\u3044\u306e\u6642\u9593\u88c5\u7740\u3059\u308b\u304b (compliance) \u3067\u5168\u751f\u5b58\u671f\u9593\u306b\u5dee\u304c\u3042\u308b\u3068\u3044\u3046\u5831\u544a\u304c\u306a\u3055\u308c\u307e\u3057\u305f\u300290%\u306e\u6642\u9593\u88c5\u7740\u3067\u306f\u5168\u751f\u5b58\u671f\u9593\u306f24.9\u30f6\u6708\uff0c70-80%\u306e\u88c5\u7740\u6642\u9593\u3067\u306f\u5168\u751f\u5b58\u671f\u9593\u4e2d\u592e\u502421.7\u30f6\u6708\u3067\u3057\u305f\u3002\u901a\u5e38\u63a8\u5968\u3055\u308c\u308b\u306e\u304c70-80%\u4ee5\u4e0a\uff081\u65e518\u6642\u9593\u4ee5\u4e0a\uff09\u306e\u88c5\u7740\u3067\u3059\u3002<br \/>\n\u306a\u308b\u3079\u304f\u9577\u3044\u6642\u9593\u88c5\u7740\u3057\u305f\u307b\u3046\u304c\u3044\u3044\u3068\u3044\u3046\u306e\u306f\u7406\u8ad6\u7684\u306b\u3082\u5f53\u7136\u306e\u3053\u3068\u304b\u3082\u3057\u308c\u307e\u305b\u3093\u304c\uff0c\u982d\u76ae\u306e\u4e7e\u71e5\u3068\u4fdd\u8b77\u306e\u305f\u3081\u306b90%\u306f\u96e3\u3057\u3044\u3053\u3068\u3082\u3042\u308a\u307e\u3059\u3002<\/p>\n<h5>\u88c5\u7f6e\u306e\u5024\u6bb5\u304c\u9ad8\u3059\u304e\u308b<\/h5>\n<p>Bernard-Arnoux F, et al. : The\u00a0cost-effectiveness\u00a0of\u00a0tumor-treating\u00a0fields\u00a0therapy\u00a0in\u00a0patients\u00a0with newly diagnosed glioblastoma. Neuro Oncol\u00a02016<br \/>\n\u30d5\u30e9\u30f3\u30b9\u304b\u3089\u306e\u5831\u544a\u3067\u3059\u3002TTF\u6cbb\u7642\u306e\u30b3\u30b9\u30c8\u306f\u3068\u3066\u3082\u9ad8\u984d\u3067\uff0c\u8cbb\u7528\u5bfe\u52b9\u679c\u3092\u898b\u305f\u5834\u5408\uff0c<span style=\"color: #000080;\"><strong>\u5f93\u6765\u8a31\u5bb9\u3055\u308c\u3066\u6765\u305f\u4fdd\u967a\u8a3a\u7642\u306e\u30b3\u30b9\u30c8\u3092\u306f\u308b\u304b\u306b\u8d85\u3048\u308b\u3082\u306e\u3060\u3068\u7d50\u8ad6<\/strong><\/span>\u3057\u3066\u3044\u307e\u3059\u3002\u4fdd\u5065\u5f53\u5c40\u304c\u624b\u9803\u306a\u5024\u6bb5\u306b\u3059\u308c\u3070\u4f7f\u7528\u3067\u304d\u308b\u304b\u3082\u3057\u308c\u307e\u305b\u3093\u3002\u3067\u306a\u3051\u308c\u3070\uff0c\u7121\u7406\uff01<br \/>\n\u65e5\u672c\u56fd\u306f\u305d\u3093\u306a\u3053\u3068\u306f\u8003\u3048\u306a\u3044\u306e\u3067\uff0c\u65e5\u672c\u3067\u306f\u4f7f\u3063\u3066\u3082\u3044\u3044\u3067\u3059\u3002<\/p>\n<h5>\u521d\u767a\u3067\u72b6\u614b PS \u306e\u826f\u3044\u60a3\u8005\u3055\u3093\u3078\u306e\u9069\u5fdc<\/h5>\n<p>2015\u5e74\u306e\u7b2c\uff13\u76f8\u8a66\u9a13\u306e\u7d50\u679c\u3092\u53d7\u3051\u3066\uff0cThe National Comprehensive Cancer Network (NCCN)\u304ccategory 2A recommendation\u3068\u3057\u307e\u3057\u305f\u30022016\u5e747\u6708\u306b\u306f1.3kg\u306b\u8efd\u91cf\u5316\u3055\u308c\u305f\u3082\u306e\u304cFDA\u3067\u8a8d\u53ef\u3055\u308c\u307e\u3057\u305f\u3002\u3053\u306e\u88c5\u7f6e\u306f\u65e5\u672c\u3067\uff0c2017\u5e7412\u6708\u306b\u4fdd\u967a\u9069\u5fdc\u3068\u306a\u308a\u307e\u3057\u305f\u3002<\/p>\n<h5>\u6587\u732e<\/h5>\n<h4>\u8ee2\u79fb\u6027\u8133\u816b\u760d\u3078\u306e\u52b9\u679c<\/h4>\n<p>2024\u5e74\uff0c\u8ee2\u79fb\u6027\u8133\u816b\u760d\u306e\u4e2d\u3067\u3082\u80ba\u5c0f\u7d30\u80de\u764c LSCC \u306b\u5bfe\u3057\u3066\u306e\u6709\u52b9\u6027\u304c\u81e8\u5e8a\u7b2c3\u76f8\u8a66\u9a13\u3067\u78ba\u304b\u3081\u3089\u308c\u307e\u3057\u305f\uff0cTTF\u3092\u4f7f\u7528\u3059\u308b\u3068\u982d\u84cb\u5185\u9032\u5c55\u306e\u9032\u884c\u304c11\u30f6\u6708\u304b\u308922\u30f6\u6708\u306b\u9045\u3089\u305b\u308b\u3053\u3068\u304c\u3067\u304d\u307e\u3059\u3002<br \/>\n<i>the METIS trial to be presented today during the 2024 ASCO Annual Meeting<\/i><\/p>\n<h4>\u9ad8\u9f62\u8005\u3067\u3082\u521d\u767a\u81a0\u82bd\u816b\u306b\u30c6\u30e2\u30be\u30ed\u30de\u30a4\u30c9\u3068\u306e\u4f75\u7528\u304c\u6709\u52b9<\/h4>\n<p>Efficacy and Safety of Tumor Treating Fields (TTFields) in Elderly Patients with Newly Diagnosed Glioblastoma: Subgroup Analysis of the Phase 3 EF-14 Clinical Trial. Front Oncol, 2021<br \/>\nEF-14\u306e\u30b5\u30d6\u30b0\u30eb\u30fc\u30d7\u89e3\u6790\u306e\u7d50\u679c\u3067\u3059\u300265\u6b73\u4ee5\u4e0a\u306e\u60a3\u8005\u3055\u309389\u540d\u306b\u30aa\u30d7\u30c1\u30e5\u30fc\u30f3\u304c\u4f7f\u7528\u3055\u308c\u307e\u3057\u305f\u3002\u7121\u5897\u60aa\u751f\u5b58\u671f\u9593\u306f\u30aa\u30d7\u30c1\u30e5\u30fc\u30f3\u3092\u88c5\u7740\u3057\u3066\u30c6\u30e2\u30be\u30ed\u30de\u30a4\u30c9\u3092\u4f75\u7528\u3059\u308b\u30686.5\u30f6\u6708\u3067\u3057\u305f\u3002\u88c5\u7740\u3057\u306a\u3044\u7fa4\u3067\u306f3.9\u30f6\u6708\u3067\u6709\u610f\u306a\u5dee\u304c\u3042\u3063\u305f\u3068\u306e\u3053\u3068\u3067\u3059\u3002\u5168\u751f\u5b58\u671f\u9593\u3067\u306f17.4\u30f6\u6708\u306b\u5bfe\u3057\u3066\uff0c13.7\u30f6\u6708\u3067\u3042\u308a\uff0c\u7d044\u30f6\u6708\u751f\u5b58\u671f\u9593\u304c\u5ef6\u3073\u305f\u3053\u3068\u306b\u306a\u308a\u307e\u3057\u305f\u30025\u5e74\u751f\u5b58\u5272\u5408\u3067\u306f\uff0c15%\u30680%\u3068\u3044\u3046\u5dee\u3067\u3059\u304c\u5bfe\u8c61\u6570\u304c\u5c11\u306a\u304f\u6709\u610f\u5dee\u306f\u3042\u308a\u307e\u305b\u3093\u3002<\/p>\n<h4>2016\u5e74\u306e\u5b66\u4f1a\u767a\u8868<\/h4>\n<p>Stupp R, et al: The 21st Annual Scientific Meeting of the Society for Neuro-Oncology (SNO) on Nov. 18, 2016, in Scottsdale, Arizona<br \/>\n2015\u5e74\u306b\u767a\u8868\u3055\u308c\u305f\u7b2c3\u76f8\u8a66\u9a13 EF-14 \u306e\u8ffd\u52a0\u306e\u5831\u544a\u3067\u3059\u3002\u521d\u767a\u306e\u81a0\u82bd\u816b\u306e\u60a3\u8005\u3055\u3093\u3067\u30c6\u30e2\u30be\u30ed\u30de\u30a4\u30c9\u306e\u307f\u3067\u306f2\u5e74\u751f\u5b58\u5272\u5408\u306f30%\u3067\u3057\u305f\u304c\uff0c\u30aa\u30d7\u30c1\u30e5\u30fc\u30f3\u306e\u4f75\u7528\u3067\u306f43%\u3067\u3057\u305f\u30024\u5e74\u751f\u5b58\u5272\u5408\u3067\u3082\uff0c\u305d\u308c\u305e\u308c10%\u306817%\u3067\uff0c\u30aa\u30d7\u30c1\u30e5\u30fc\u30f3\u304c7%\u4e0a\u56de\u308a\u307e\u3059\u3002<\/p>\n<h4>2015\u5e74\u306e\u8ad6\u6587\u767a\u8868<\/h4>\n<p>Stupp R, et al.: Maintenance Therapy With Tumor-Treating Fields Plus Temozolomide vs Temozolomide Alone for Glioblastoma: A Randomized Clinical Trial. JAMA 314, 2015<br \/>\nTTF\u3068\u30c6\u30e2\u30be\u30ed\u30de\u30a4\u30c9 210\u4eba\uff0c\u30c6\u30e2\u30be\u30ed\u30de\u30a4\u30c9\u306e\u307f105\u4eba\u306e\u521d\u767a\u81a0\u82bd\u816b\u306e\u60a3\u8005\u3055\u3093\u3067\u7121\u4f5c\u70ba\u8a66\u9a13\u304c\u884c\u308f\u308c\u307e\u3057\u305f\u3002PFS\u306f\u305d\u308c\u305e\u308c7.1\u30f6\u6708\u30684\u30f6\u6708\uff0cOS\u306f20.5\u30f6\u6708 (n=196)\u306815.6\u30f6\u6708 (n=86)\u3067\u3057\u305f\u3002\u75c7\u72b6\u304c\u60aa\u304f\u306a\u3089\u306a\u3044\u3067\u751f\u5b58\u3067\u304d\u308b\u671f\u9593\u304c3\u304b\u6708\u307b\u3069\u5ef6\u3073\u308b\uff0c\u5168\u751f\u5b58\u671f\u9593\u306b\u5bfe\u3059\u308b\u5229\u70b9\u304c\uff15\u30f6\u6708\u307b\u3069\u3042\u308b\u3068\u3044\u3046\u3053\u3068\u304c\u5831\u544a\u3055\u308c\u307e\u3057\u305f\u3002<br \/>\nDuke\u5927\u5b66\u306eSampson LH\u306f\u5316\u5b66\u7642\u6cd5\u306e\u52b9\u679c\u3092\u3042\u3052\u308b\u6a5f\u5e8f\u304c\u4e0d\u660e\u3067\u3042\u308b\u3068\u30b3\u30e1\u30f3\u30c8\u3057\u3066\u3044\u307e\u3059\u3002\u66f4\u306b\uff0cBecause of the study design chosen, doubts may remain as to the true efficacy of this therapy. \u3068\u4ed8\u3051\u52a0\u3048\u3066\u3044\u307e\u3059\u3002<\/p>\n<h4>2012\u5e74\u306e\u8ad6\u6587\u5831\u544a\uff08\u518d\u767a\u81a0\u82bd\u816b\u306e\u751f\u5b58\u671f\u9593\u3092\u5ef6\u9577\u3057\u306a\u3044\uff09<\/h4>\n<p align=\"left\">Stupp R, et al.: NovoTTF-100A versus physician&#8217;s choice chemotherapy in recurrent glioblastoma: a randomised phase III trial of a novel treatment modality. Eur J Cancer 48: 2192-2202, 2012<br \/>\n\u8ad6\u6587\u5831\u544a\u306f\uff0c\u81e8\u5e8a\u7b2c\uff13\u76f8\u8a66\u9a13\u306e\u7d50\u679c\u3067\u3059\u3002\u518d\u767a\u81a0\u82bd\u816b\u306e\u60a3\u8005\u3055\u3093237\u4eba\u304c\u7121\u4f5c\u70ba\u8a66\u9a13\u3067\u6cbb\u7642\u3092\u53d7\u3051\u307e\u3057\u305f\u3002\u5e74\u9f62\u306f23\u221280\u6b73\uff0cKPS\u306f50-100%\u3067\u3059\u3002TTF\u306f120\u4eba\u306e\u60a3\u8005\u3055\u3093\u306b\u4f7f\u7528\u3055\u308c\uff0c\u4e3b\u6cbb\u533b\u306e\u5148\u751f\u304c\u9078\u3093\u3060\u5316\u5b66\u7642\u6cd5\u306f117\u4eba\u306e\u60a3\u8005\u3055\u3093\u306b\u884c\u306a\u308f\u308c\u307e\u3057\u305f\u3002\u751f\u5b58\u671f\u9593\u4e2d\u592e\u5024\u306f6.6\u30f6\u6708\u30686.0\u30f6\u6708\uff0c1\u5e74\u751f\u5b58\u5272\u5408\u306f20%\u306820%\uff0c\uff16\u30f6\u6708\u7121\u5897\u60aa\u751f\u5b58\u5272\u5408\u306f21.4%\u306815.1%\u3067\u3057\u305f\u3002TTF\u3068active chemotherapy\u306e\u9593\u306b\u5168\u304f\u5dee\u306f\u3042\u308a\u307e\u305b\u3093\u3067\u3057\u305f\u3002\u816b\u760d\u306e\u7e2e\u5c0f\u7387\u306f\uff0c14%\u30689.6%\u3067\u6709\u610f\u5dee\u306f\u306a\u3044\u3082\u306e\u306eTTF\u306e\u65b9\u304c\u512a\u3063\u305f\u3068\u306e\u3053\u3068\u3067\u3059\u3002<br \/>\n\u300c\u89e3\u8aac\u300d\u5f31\u3044\u4ea4\u6d41\u96fb\u5834\u3092\u8133\u5185\u306b\u4f5c\u308b\u3060\u3051\u3067\u3059\u304b\u3089\uff0c\u96fb\u6975\u30d0\u30c3\u30c9 transducer \u306e\u4e0b\u306e\u982d\u76ae\u306e\u8352\u308c\uff08\u63a5\u89e6\u6027\u76ae\u819a\u708e\uff09\u4ee5\u5916\u306b\u306f\uff0c\u6709\u5bb3\u4e8b\u8c61\u3068\u3044\u3046\u306e\u306f\u307b\u3068\u3093\u3069\u3042\u308a\u307e\u305b\u3093\u3002\u6ce8\u610f\u3057\u305f\u3044\u306e\u306f\uff0c\u3082\u3068\u3082\u3068\u518d\u767a\u81a0\u82bd\u816b\u306b\u6709\u52b9\u306a\u5316\u5b66\u7642\u6cd5\u3068\u3044\u3046\u306e\u306f\u3042\u308a\u307e\u305b\u3093\u304b\u3089\uff0c\u305d\u308c\u3068\u6bd4\u8f03\u3057\u3066\u975e\u52a3\u6027\u8a66\u9a13\u3092\u884c\u3063\u3066\u3082\uff0cTTF\u306b\u6709\u52b9\u6027\u304c\u3042\u308b\u3068\u8a00\u3048\u308b\u308f\u3051\u3067\u306f\u306a\u3044\u3053\u3068\u3067\u3059\u3002<\/p>\n<p align=\"left\"><a href=\"https:\/\/plaza.umin.ac.jp\/sawamura\/blog\/wp-content\/uploads\/2014\/04\/optune402.jpg\"><img loading=\"lazy\" decoding=\"async\" class=\"alignnone size-large wp-image-22016\" src=\"https:\/\/plaza.umin.ac.jp\/sawamura\/blog\/wp-content\/uploads\/2014\/04\/optune402-550x513.jpg\" alt=\"\" width=\"550\" height=\"513\" srcset=\"https:\/\/plaza.umin.ac.jp\/sawamura\/blog\/wp-content\/uploads\/2014\/04\/optune402-550x513.jpg 550w, https:\/\/plaza.umin.ac.jp\/sawamura\/blog\/wp-content\/uploads\/2014\/04\/optune402-300x280.jpg 300w, https:\/\/plaza.umin.ac.jp\/sawamura\/blog\/wp-content\/uploads\/2014\/04\/optune402-768x716.jpg 768w, https:\/\/plaza.umin.ac.jp\/sawamura\/blog\/wp-content\/uploads\/2014\/04\/optune402.jpg 984w\" sizes=\"auto, (max-width: 550px) 100vw, 550px\" \/><\/a><\/p>\n<p align=\"left\"><a href=\"https:\/\/plaza.umin.ac.jp\/sawamura\/blog\/wp-content\/uploads\/2014\/04\/novottf2-1.jpg\"><img loading=\"lazy\" decoding=\"async\" class=\"alignleft size-medium wp-image-22014\" src=\"https:\/\/plaza.umin.ac.jp\/sawamura\/blog\/wp-content\/uploads\/2014\/04\/novottf2-1-294x300.jpg\" alt=\"\" width=\"294\" height=\"300\" srcset=\"https:\/\/plaza.umin.ac.jp\/sawamura\/blog\/wp-content\/uploads\/2014\/04\/novottf2-1-294x300.jpg 294w, https:\/\/plaza.umin.ac.jp\/sawamura\/blog\/wp-content\/uploads\/2014\/04\/novottf2-1-550x561.jpg 550w, https:\/\/plaza.umin.ac.jp\/sawamura\/blog\/wp-content\/uploads\/2014\/04\/novottf2-1.jpg 709w\" sizes=\"auto, (max-width: 294px) 100vw, 294px\" \/><\/a><br \/>\n\u30ea\u30e5\u30c3\u30af\u30bf\u30a4\u30d7\u306e\u643a\u5e2f\uff0c\u5916\u51fa\u3084\u81ea\u5b85\u3067\u30aa\u30d7\u30c1\u30e5\u30fc\u30f3\u3092\u88c5\u7740\u3057\u3066\u3044\u308b\u60a3\u8005\u3055\u3093\u3067\u3059\u3002<br \/>\n\u4e0b\u306f\u30b7\u30e7\u30eb\u30c0\u30fc\u30bf\u30a4\u30d7\u3002<\/p>\n<h4 align=\"left\">\u306a\u305c\u52b9\u304f\u306e\u304b<\/h4>\n<ul>\n<li>\u00a0\u306f\u3063\u304d\u308a\u306f\u89e3\u3063\u3066\u3044\u307e\u305b\u3093<\/li>\n<li>\u88c5\u7f6e\u306f\u816b\u760d\u7d30\u80de\u306e\u5185\u90e8\u306b\u96fb\u5834\u3092\u767a\u751f\u3055\u305b\u307e\u3059<\/li>\n<li>\u7d30\u80de\u5185\u306e\u96fb\u8377\u3092\u5e2f\u3073\u305f\u7c92\u5b50 particle\u3092\u52d5\u304b\u3059\u3053\u3068\u306b\u3088\u3063\u3066\u52b9\u679c\u3092\u51fa\u3057\u307e\u3059<\/li>\n<li>\u7d30\u80de\u9aa8\u683c\u3092\u69cb\u6210\u3059\u308bmicrotubules\u306a\u3069\u50cd\u304d\u3092\u6291\u5236\u3059\u308b\u3057\u3066\u7d30\u80de\u5206\u88c2\u3092\u59a8\u3052\u308b\u3068\u63a8\u5b9a\u3055\u308c\u3066\u3044\u307e\u3059<\/li>\n<li>\u7d30\u80de\u9aa8\u683c\u304c\u67d3\u8272\u4f53\u3092\u96c6\u3081\u305f\u308aaggregation \u96e2\u3057\u305f\u308a segregation\u3059\u308b\u3053\u3068\u304c\u6291\u5236\u3055\u308c\u308b\u305f\u3081\u306b\u816b\u760d\u7d30\u80de\u304c\u5897\u6b96\u3067\u304d\u306a\u3044\u3068\u3044\u3046\u3053\u3068\u3067\u3059<\/li>\n<li>\u4ed6\u306b\u306f\uff0c\u7d30\u80de\u304c\u4e8c\u3064\u306b\u5206\u304b\u308c\u308b\u6642\u306b\u5f62\u8cea\u819c\u3092\u640d\u50b7\u3057\u3066\u816b\u760d\u7d30\u80de\u6b7b\u3092\u751f\u3058\u308b\uff0c\u816b\u760d\u7d30\u80de\u306eDNA\u4fee\u5fa9\u80fd\u3092\u963b\u5bb3\u3059\u308b\u306a\u3069\u3067\u3059<\/li>\n<\/ul>\n<hr \/>\n<h5>\u8133\u5916\u79d1\u306e\u5148\u751f\u3078<\/h5>\n<h5>\u521d\u767a\u81a0\u82bd\u816b\u306e\u4fdd\u967a\u8a3a\u7642<\/h5>\n<h5>\u81a0\u82bd\u816b\u306b\u5bfe\u3059\u308b\u521d\u3081\u3066\u306e\u6cbb\u7642\u306b\u306f\u4fdd\u967a\u8a3a\u7642\u304c\u8a8d\u53ef\u3055\u308c\u307e\u3057\u305f\u3002\u4f7f\u7528\u306b\u306f\u6708\u306b140\u4e07\u5186\uff0c\u5e74\u9593\u30671,700\u4e07\u5186\u304f\u3089\u3044\u306e\u533b\u7642\u8cbb\u304c\u304b\u304b\u308a\u307e\u3059\u3002\u3053\u306e\u91d1\u984d\u306f\u5b9f\u969b\u306b\u306f\u9ad8\u984d\u533b\u7642\u306b\u306a\u308a\u307e\u3059\u304b\u3089\uff0c\u6708\u306e\u9650\u5ea6\u984d\u306e\u307f\u304c\u6bce\u6708\u306e\u60a3\u8005\u3055\u3093\u306e\u8ca0\u62c5\u3068\u306a\u308a\u307e\u3059\u3002\u518d\u767a\u306e\u81a0\u82bd\u816b\u306b\u306f\u4eca\u307e\u3067\u3069\u304a\u308a\u5168\u984d\u81ea\u5df1\u8ca0\u62c5\u306b\u306a\u308a\u307e\u3059\u304b\u3089\uff0c\u5343\u4e07\u5186\u5358\u4f4d\u306e\u6cbb\u7642\u8cbb\u304c\u304b\u304b\u308a\u307e\u3059\u3002<\/h5>\n<h5>\u518d\u767a\u306b\u5bfe\u3057\u3066<\/h5>\n<h5>\u6700\u8fd1\uff0c\u795e\u7d4c\u81a0\u816b\u304c\u518d\u767a\u3057\u305f\u60a3\u8005\u3055\u3093\u304b\u3089NovoTTF\u306e\u6cbb\u7642\u3092\u533b\u5e2b\u304b\u3089\u52e7\u3081\u3089\u308c\u305f\u3068\u3044\u3046\u76f8\u8ac7\u3092\u53d7\u3051\u307e\u3059\u3002\u3053\u306e\u6cbb\u7642\u306f\u4fdd\u967a\u8a3a\u7642\u304c\u3067\u304d\u307e\u305b\u3093\u304b\u3089\uff0c<span style=\"color: #ff0000;\">\u518d\u767a\u306b\u306f<strong>\u4e00\u5e74\u9593\u306b\u6570\u5343\u4e07\u5186\u306e\u304a\u91d1\uff08\u5b9f\u8cbb\uff09<\/strong><\/span>\u304c\u304b\u304b\u308a\u307e\u3059\u3002\u60a3\u8005\u3055\u3093\u306b\u3053\u306e\u6cbb\u7642\u3092\u8aac\u660e\u3059\u308b\u524d\u306b\uff0c\u60a3\u8005\u3055\u3093\u3068\u5bb6\u65cf\u304c\u5c06\u6765\u3092\u5931\u308f\u306a\u3044\u3067\u3053\u306e\u6599\u91d1\u3092\u652f\u6255\u3048\u308b\u304b\u3069\u3046\u304b\u8003\u3048\u3066\u304b\u3089\uff0c\u52e7\u3081\u3066\u4e0b\u3055\u3044\u3002\u3067\u306a\u3044\u3068\u3001\u304a\u91d1\u304c\u306a\u3044\u3068\u3044\u3046\u3053\u3068\u3067\u54c0\u3057\u3044\u60f3\u3044\u3092\u3059\u308b\u3060\u3051\u3067\u3059\u3002\u307e\u305f\u9ad8\u984d\u306a\u533b\u7642\u8cbb\u3068\u4e0d\u4fbf\u6027\u304c\u3042\u308b\u4e00\u65b9\u3067\uff0c\u6570\u30f6\u6708\u306e\u5ef6\u547d\u304c\u3067\u304d\u308b\u3060\u3051\u3067\u3001\u81a0\u82bd\u816b\u304c\u6cbb\u308b\u3068\u3044\u3046\u3053\u3068\u306f\u306a\u3044\u6cbb\u7642\u6cd5\u3067\u3059\u3002<\/h5>\n<p>&nbsp;<\/p>\n<p><img loading=\"lazy\" decoding=\"async\" class=\"alignright size-medium wp-image-8225\" src=\"\/sawamura\/blog\/wp-content\/uploads\/2014\/04\/frog-300x225.jpg\" alt=\"frog\" width=\"300\" height=\"225\" srcset=\"https:\/\/plaza.umin.ac.jp\/sawamura\/blog\/wp-content\/uploads\/2014\/04\/frog-300x225.jpg 300w, https:\/\/plaza.umin.ac.jp\/sawamura\/blog\/wp-content\/uploads\/2014\/04\/frog-550x413.jpg 550w, https:\/\/plaza.umin.ac.jp\/sawamura\/blog\/wp-content\/uploads\/2014\/04\/frog-900x675.jpg 900w\" sizes=\"auto, (max-width: 300px) 100vw, 300px\" \/><\/p>\n<h4>\u30aa\u30d7\u30c1\u30e5\u30fc\u30f3\u304c\u4f7f\u3048\u306a\u3044\u72b6\u6cc1\uff08\u7981\u5fcc\uff09<\/h4>\n<ul>\n<li>\u6e1b\u5727\u958b\u982d\u3084\u611f\u67d3\u306a\u3069\u3067\u9aa8\u5f01\u304c\u5916\u3057\u3066\u3042\u3063\u3066\u982d\u84cb\u9aa8\u6b20\u640d\u304c\u3042\u308b\u6642<\/li>\n<li>\u982d\u306e\u4e2d\u306b\u5f3e\u4e38\u306e\u7834\u7247\u306a\u3069\u306e\u91d1\u5c5e\u306e\u584a\u304c\u3042\u308b\u6642<\/li>\n<li>\u30da\u30fc\u30b9\u30e1\u30fc\u30ab\u30fc\u306a\u3069\u306e\u57cb\u3081\u8fbc\u307f\u578b\u306e\u533b\u7642\u88c5\u7f6e\u3092\u88c5\u7740\u3057\u3066\u3044\u308b\u6642<\/li>\n<\/ul>\n<h5>\u304a\u307e\u3051<\/h5>\n<p>\u30c6\u30e2\u30be\u30ed\u30de\u30a4\u30c9\u3067\u521d\u767a\u81a0\u82bd\u816b\u306eOS\u304c15\u30f6\u6708\u3068\u306a\u3063\u305f\u3068\u3044\u3046\u9a5a\u304d\u306f\uff0c2005\u5e74\u306e\u3082\u306e\u3067\u3057\u305f\u3002\u300c\u30aa\u30d7\u30c1\u30e5\u30fc\u30f3\u3092\u4f7f\u7528\u3059\u308b\u3068OS\u304c21\u30f6\u6708\u306b\u3082\u4f38\u3073\u308b\uff01\u300d\uff0c\u3059\u3054\u304f\u9a5a\u304d\u307e\u305b\u3093\u304b\uff1f<br \/>\n\u30aa\u30d7\u30c1\u30e5\u30fc\u30f3\u306e\u81e8\u5e8a\u7814\u7a76\u306b\u767b\u9332\u3055\u308c\u305f\u60a3\u8005\u3055\u3093\u306f\uff0c\u8a3a\u65ad\u304b\u3089\u30e9\u30f3\u30c0\u30e0\u5316\u307e\u30673.8\u30f6\u6708\u304b\u304b\u3063\u3066\u3044\u307e\u3059\u3002\u624b\u8853\uff0c\u75c5\u7406\uff0c\u653e\u5c04\u7dda\u5316\u5b66\u7642\u6cd5\u306b\u6642\u9593\u304c\u8cbb\u3084\u3055\u308c\u3044\u3066\u308b\u304b\u3089\u3067\u3059\u3002\u3053\u306e\u671f\u9593\u306b\u3059\u3067\u306b30%\u4ee5\u4e0a\u306e\u60a3\u8005\u3055\u3093\u3067\u60aa\u5316 progression\u304c\u3042\u308a\uff0c\u3053\u308c\u3089\u4e88\u5f8c\u306e\u7279\u306b\u60aa\u3044\u65e9\u671f\u5897\u60aa early progression\u3092\u5448\u3059\u308b\u81a0\u82bd\u816b\u60a3\u8005\u3055\u3093\u304c\uff0c\u767b\u9332\u6642\u70b9\u3067\u7701\u304b\u308c\u3066\u3044\u308b\u304b\u3089\u3067\u3059\uff0c\u3075\u308b\u3044\u843d\u3068\u3057\u5f8c\u306e\u8a66\u9a13\u3068\u8a00\u3044\u307e\u3059\u3002\u89e3\u3063\u3066\u304f\u3060\u3055\u3063\u305f\u3067\u3057\u3087\u3046\u304b\u3002<\/p>\n<h5>\u304a\u307e\u3051<\/h5>\n<p>\u653e\u5c04\u7dda\u88ab\u66dd\u3092\u53d7\u3051\u308b\u3068\u9ac4\u819c\u816b\u3084\u30b0\u30ea\u30aa\u30fc\u30de\u304c\u767a\u751f\u3059\u308b\u3068\u3044\u3046\u3053\u3068\u306f\u53e4\u304f\u304b\u3089\u77e5\u3089\u308c\u3066\u3044\u307e\u3057\u305f\u3002\u96fb\u78c1\u6ce2\u306b\u95a2\u3057\u3066\u3082\u9577\u304f\u305d\u306e\u7591\u3044\u304c\u3042\u308a\u307e\u3057\u305f\u304c\uff0c2018\u5e74\u306bINTEROCC\u75ab\u5b66\u8abf\u67fb\u306e\u7d50\u679c\u304c\u767a\u8868\u3055\u308c\uff0c\u96fb\u78c1\u6ce2\u306f\u3053\u308c\u3089\u306e\u8133\u816b\u760d\u3092\u767a\u751f\u3055\u305b\u308b\u30ea\u30b9\u30af\u306f\u306a\u3044\u3068\u3055\u308c\u307e\u3057\u305f\u3002<\/p>\n<p><a href=\"https:\/\/plaza.umin.ac.jp\/sawamura\/blog\/wp-content\/uploads\/2014\/04\/novottf3.jpg\"><img loading=\"lazy\" decoding=\"async\" class=\"alignleft size-large wp-image-11477\" src=\"https:\/\/plaza.umin.ac.jp\/sawamura\/blog\/wp-content\/uploads\/2014\/04\/novottf3-550x367.jpg\" alt=\"\" width=\"550\" height=\"367\" srcset=\"https:\/\/plaza.umin.ac.jp\/sawamura\/blog\/wp-content\/uploads\/2014\/04\/novottf3-550x367.jpg 550w, https:\/\/plaza.umin.ac.jp\/sawamura\/blog\/wp-content\/uploads\/2014\/04\/novottf3-300x200.jpg 300w, https:\/\/plaza.umin.ac.jp\/sawamura\/blog\/wp-content\/uploads\/2014\/04\/novottf3-768x512.jpg 768w, https:\/\/plaza.umin.ac.jp\/sawamura\/blog\/wp-content\/uploads\/2014\/04\/novottf3.jpg 850w\" sizes=\"auto, (max-width: 550px) 100vw, 550px\" \/><\/a><\/p>\n<p>\u30aa\u30d7\u30c1\u30e5\u30fc\u30f3\u306e\u88c5\u7740\u753b\u50cf\u306fNOVOCURE\u793e\u3088\u308a\u63d0\u4f9b\u3092\u53d7\u3051\u307e\u3057\u305f<\/p>\n<h5><\/h5>\n<p>&nbsp;<\/p>\n","protected":false},"excerpt":{"rendered":"<p>TTF tumor treating fields\u3068\u3044\u3046\u540d\u524d\u306e\u6cbb\u7642\u6cd5\u3067\u3059 \u6b63\u5f0f\u306b\u306f\u300c\u4ea4\u6d41\u96fb\u5834\u816b\u760d\u6cbb\u7642\u30b7\u30b9\u30c6\u30e0\u300d\u3068\u8a33\u304c\u6c7a\u307e\u308a\u307e\u3057\u305f 2017\u5e74\u306b\uff0c\u521d\u767a\u81a0\u82bd\u816b\u751f\u5b58\u671f\u9593\u4e2d\u592e\u5024\u30924 &#8211; 5\u30f6\u6708\u307b\u3069\u5ef6\u9577\u3059\u308b\u3068\u6700\u7d42\u5831\u544a\u304c [&hellip;]<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[16],"tags":[],"class_list":["post-4927","post","type-post","status-publish","format-standard","hentry","category-glioma"],"aioseo_notices":[],"_links":{"self":[{"href":"https:\/\/plaza.umin.ac.jp\/sawamura\/blog\/wp-json\/wp\/v2\/posts\/4927","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/plaza.umin.ac.jp\/sawamura\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/plaza.umin.ac.jp\/sawamura\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/plaza.umin.ac.jp\/sawamura\/blog\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/plaza.umin.ac.jp\/sawamura\/blog\/wp-json\/wp\/v2\/comments?post=4927"}],"version-history":[{"count":80,"href":"https:\/\/plaza.umin.ac.jp\/sawamura\/blog\/wp-json\/wp\/v2\/posts\/4927\/revisions"}],"predecessor-version":[{"id":22758,"href":"https:\/\/plaza.umin.ac.jp\/sawamura\/blog\/wp-json\/wp\/v2\/posts\/4927\/revisions\/22758"}],"wp:attachment":[{"href":"https:\/\/plaza.umin.ac.jp\/sawamura\/blog\/wp-json\/wp\/v2\/media?parent=4927"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/plaza.umin.ac.jp\/sawamura\/blog\/wp-json\/wp\/v2\/categories?post=4927"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/plaza.umin.ac.jp\/sawamura\/blog\/wp-json\/wp\/v2\/tags?post=4927"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}