研究業績 2009年

  • Hisaka A, Kusama M, Ohno Y, Sugiyama Y, and Suzuki H. A proposal for a pharmacokinetic interaction significance classification system (PISCS) based on predicted drug exposure changes and its potential application to alert classifications in product labelling. Clin Pharmacokinet 48: 653-666, (2009). [abstract]
  • Ikebuchi Y, Takada T, Ito K, Yoshikado T, Anzai N, Kanai Y, and Suzuki H. Receptor for activated C-kinase 1 regulates the cellular localization and function of ABCB4. Hepatol Res 39: 1091-1107, (2009). [abstract]
  • Kariya Y, Honma M, Aoki S, Chiba A, and Suzuki H. Vps33a mediates RANKL storage in secretory lysosomes in osteoblastic cells. J Bone Miner Res 24: 1741-1752, (2009). [abstract]
  • Koh S, Takada T, Kukuu I, and Suzuki H. FIC1-mediated stimulation of FXR activity is decreased with PFIC1 mutations in HepG2 cells. J Gastroenterol 44: 592-600, (2009). [abstract]
  • Kozawa M, Honma M, and Suzuki H. Quantitative prediction of in vivo profiles of CYP3A4 induction in humans from in vitro results with a reporter gene assay. Drug Metab Dispos 37: 1234-1241, (2009). [abstract]
  • Li T, Ito K, Sumi S, Fuwa T, and Horie T. Protective effect of aged garlic extract (AGE) on the apoptosis of intestinal epithelial cells caused by methotrexate. Cancer Chemother Pharmacol 63: 873-880, (2009). [abstract]
  • Matsuo H, Takada T, Ichida K, Nakamura T, Nakayama A, Ikebuchi Y, Ito K, Kusanagi Y, Chiba T, Tadokoro S, Takada Y, Oikawa Y, Inoue H, Suzuki K, Okada R, Nishiyama J, Domoto H, Watanabe S, Fujita M, Morimoto Y, Naito M, Nishio K, Hishida A, Wakai K, Asai Y, Niwa K, Kamakura K, Nonoyama S, Sakurai Y, Hosoya T, Kanai Y, Suzuki H, Hamajima N, and Shinomiya N. Common Defects of ABCG2, a High-capacity Urate Exporter, Cause Gout: A Function-based Genetic Analysis in a Japanese Population. Science Translational Medicine 1: 41-48, (2009). [abstract] [論文DL[プレスリリース]
  • Minami S, Ito K, Honma M, Ikebuchi Y, Anzai N, Kanai Y, Nishida T, Tsukita S, Sekine S, Horie T, and Suzuki H. Posttranslational regulation of Abcc2 expression by SUMOylation system. Am J Physiol Gastrointest Liver Physiol 296: G406-413, (2009). [abstract]
  • Nakano T, Sekine S, Ito K, and Horie T. Correlation between apical localization of Abcc2/Mrp2 and phosphorylation status of ezrin in rat intestine. Drug Metab Dispos 37: 1521-1527, (2009). [abstract]
  • Yamanashi Y, Takada T, and Suzuki H. In-vitro characterization of the six clustered variants of NPC1L1 observed in cholesterol low absorbers. Pharmacogenet Genomics 19: 884-892, (2009). [abstract]