1.Vacuolar
1)Lymphocyte predominant
a)Basement mermbrane sometimes thickened.
smudged interface. thinned epidermis
Discoid lupus erythematosus
b) Individual necrotic keratinocytes. ballooning, parakeratosis
Mucha-Habermann disease
2)Neutrophiles and eosinophiles prominent
a)Individual necrotic keratinocytes. ballooning
Fixed drug eruption
2.Lichenoid
1)Lymphocytes predominent
a)Eosinophils sometimes. focal parakeratosis
Lichenoid drug eruption
b)Individual necrotic keratinocytes sometimes
Lichenoid photoderrnatitis
c) Individual necrotic keratinocytes. ballooning, spongiosis
Mucha-Habermann disease
d)Thickened basement membrane, smudged appearance of interface.
thinned epidermis focally
Discoid lupus erythematosus
e)Thinned epiderrnis, prorninent granular layer, parakeratosis
Graft vs. host reaction
f)Abnorrnal lyrnphocytes in wedge-shaped infiltrate often plasma cells.
eosinophils, and neutrophils, as well as small lyrmphocytes
Lymphomatoid papulosis
g)Lymphocytes in epidermis. scant spongiosis
Mycosis fungoides, plaque
2)Neutrophiles,eosinophiles and plasma cells prominent
a)Abnormal lyrnphocytes in wedge-shaped infiltrate
Lymphomatoid papulosis