INTERFACE


1.Vacuolar

 

1)Lymphocyte predominant

a)Basement mermbrane sometimes thickened. smudged interface. thinned epidermis

Discoid lupus erythematosus

b) Individual necrotic keratinocytes. ballooning, parakeratosis

Mucha-Habermann disease

2)Neutrophiles and eosinophiles prominent

a)Individual necrotic keratinocytes. ballooning

Fixed drug eruption

2.Lichenoid

        

1)Lymphocytes predominent

a)Eosinophils sometimes. focal parakeratosis

Lichenoid drug eruption

b)Individual necrotic keratinocytes sometimes

Lichenoid photoderrnatitis

c) Individual necrotic keratinocytes. ballooning, spongiosis

Mucha-Habermann disease

d)Thickened basement membrane, smudged appearance of interface. thinned epidermis focally

Discoid lupus erythematosus

e)Thinned epiderrnis, prorninent granular layer, parakeratosis

Graft vs. host reaction

f)Abnorrnal lyrnphocytes in wedge-shaped infiltrate often plasma cells. eosinophils, and neutrophils, as well as small lyrmphocytes

Lymphomatoid papulosis

g)Lymphocytes in epidermis. scant spongiosis

Mycosis fungoides, plaque

2)Neutrophiles,eosinophiles and plasma cells prominent

a)Abnormal lyrnphocytes in wedge-shaped infiltrate

Lymphomatoid papulosis

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