1.Perivascular only
1)Lymphocyte predominant
a)No other change
Polyrnorphous light eruption,early
Erythema figuratum
Erythema chronicum migrans
Pernio
Erytherna nodosum (no subcutaneousfat in
superficial biopsy specirnen)
b) Marked edema in papillary dermis
Polyrnorphous light eruption
c)Abundant mucin in reticular dermis
Discoid lupus erythernatosus, tumid
d)Nuclei of lymphocytes crenulated
Chronic lyrnphocytic leukernia
B-cell lymphoma
2)Eosinophiles prominent
a)Wedge shaped infiltrate
Arthropod assault and sirnulators of it.
3)Plasma cells prominent
Erythema chronicum migrans
Scleroderma
4) Histiocytes and lymphocytes prominent
Leprosy indeterminant
2.Perivascular and Interstitial
1)Neutrophiles prominent
a)Neutrophiles splayed between colagen bundles in focus
in reticular dermis
Supprative folliculitis(periphery of lesion)
b)Neutrophiles in and around eccrine gland
Neutrophilic eccrine hidradenitis
c)Wedge-shaped infiltrate
flea bite
d)Sparse infiltrate,neutrophiles splayed between
collagen bundles in reticular dermis
cellulitis
e)Rims of homogenous materialaround venules
in upper part of dermis
Erythropoietic protoporphyria
2)Eosinophiles prominent
a)Wedge-shaped infiltrate
Arthropood assault and aimulators of it
Erythema chronicum migrans
b)"Flame figures"ina variable numbers
Well's syndrome
3)Eosinophiles and neutrophiles
a)Sparse infiltrate
Urticaria
4)Plasma cells present
a)Eosinophiles sometimes present also
Erythema chronicum migrans
5) Neutrophils, eosinophils,and plasma cells
a)"Bottom heavy" infiltrate often. hints of crowded. thickened bundles of collagen sornetimes
Scleroderrna, early
6) Histiocytes predorninate
a)mucin in center of palisades
Granulorna annulare
b)Degenerated collagen early,thickend collagen late in
center of palisades
Necrobiosis lipoidica
c)"Bottorn heavy" infiltrate often. eosinophils and neutrophils in conjunction with degeneration of collagen bundles focally
Interstitial granulornatous dermatitis with arthritis
d) Few lyrnphocytes in epidermis. scant spongiosis
Mycosis fungoides, granulornatous