NO EPIDERMAL INVOLVEMENT


1.Perivascular only

 

1)Lymphocyte predominant

a)No other change

Polyrnorphous light eruption,early Erythema figuratum Erythema chronicum migrans Pernio Erytherna nodosum (no subcutaneousfat in superficial biopsy specirnen)

b) Marked edema in papillary dermis

Polyrnorphous light eruption

c)Abundant mucin in reticular dermis

Discoid lupus erythernatosus, tumid

d)Nuclei of lymphocytes crenulated

Chronic lyrnphocytic leukernia B-cell lymphoma

2)Eosinophiles prominent

a)Wedge shaped infiltrate

Arthropod assault and sirnulators of it.

3)Plasma cells prominent

Erythema chronicum migrans Scleroderma

4) Histiocytes and lymphocytes prominent

Leprosy indeterminant

2.Perivascular and Interstitial

        

1)Neutrophiles prominent

a)Neutrophiles splayed between colagen bundles in focus in reticular dermis

Supprative folliculitis(periphery of lesion)

b)Neutrophiles in and around eccrine gland

Neutrophilic eccrine hidradenitis

c)Wedge-shaped infiltrate

flea bite

d)Sparse infiltrate,neutrophiles splayed between

collagen bundles in reticular dermis cellulitis

e)Rims of homogenous materialaround venules in upper part of dermis

Erythropoietic protoporphyria

2)Eosinophiles prominent

a)Wedge-shaped infiltrate

Arthropood assault and aimulators of it Erythema chronicum migrans

b)"Flame figures"ina variable numbers

Well's syndrome

3)Eosinophiles and neutrophiles

a)Sparse infiltrate

Urticaria

4)Plasma cells present

a)Eosinophiles sometimes present also

Erythema chronicum migrans

5) Neutrophils, eosinophils,and plasma cells

a)"Bottom heavy" infiltrate often. hints of crowded. thickened bundles of collagen sornetimes

Scleroderrna, early

6) Histiocytes predorninate

a)mucin in center of palisades

Granulorna annulare

b)Degenerated collagen early,thickend collagen late in center of palisades

Necrobiosis lipoidica

c)"Bottorn heavy" infiltrate often. eosinophils and neutrophils in conjunction with degeneration of collagen bundles focally

Interstitial granulornatous dermatitis with arthritis

d) Few lyrnphocytes in epidermis. scant spongiosis

Mycosis fungoides, granulornatous

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