{"id":2452,"date":"2021-08-23T14:45:48","date_gmt":"2021-08-23T05:45:48","guid":{"rendered":"http:\/\/plaza.umin.ac.jp\/~naoki_kondo\/?p=2452"},"modified":"2021-08-18T14:50:13","modified_gmt":"2021-08-18T05:50:13","slug":"complex-multimorbidity-and-mortality-in-japan-a-prospective-propensity-matched-cohort-study","status":"publish","type":"post","link":"http:\/\/plaza.umin.ac.jp\/~naoki_kondo\/en\/blogs\/2452","title":{"rendered":"Complex multimorbidity and mortality in Japan: a prospective propensity-matched cohort study."},"content":{"rendered":"<p>We published a study from BMJ Open.<\/p>\n<p>Kato D, Kawachi I, Saito J, Kondo N. Complex multimorbidity and mortality in Japan: a prospective propensity-matched cohort study. BMJ Open. 2021 Aug 2;11(8):e046749. <span class=\"identifier doi\"><span class=\"id-label\">DOI:\u00a0<\/span><a class=\"id-link\" href=\"https:\/\/doi.org\/10.1136\/bmjopen-2020-046749\" target=\"_blank\" rel=\"noopener\" data-ga-category=\"full_text\" data-ga-action=\"DOI\">10.1136\/bmjopen-2020-046749 <\/a><\/span>PMID: 34341044.<\/p>\n<ul id=\"full-view-identifiers\" class=\"identifiers\"><\/ul>\n<h2 class=\"title\">Abstract<\/h2>\n<div id=\"enc-abstract\" class=\"abstract-content selected\">\n<p><strong class=\"sub-title\">Objectives:\u00a0<\/strong>There are limitations to defining multimorbidity (MM) based on a simple count of diseases. To address these limitations, the concept of complex MM (CMM) focuses on how many body systems are affected in a single patient, rather than counting comorbid conditions. This study compared the prediction of mortality among older Japanese adults between CMM and conventional MM.<\/p>\n<p><strong class=\"sub-title\">Design:\u00a0<\/strong>A population-based prospective cohort study.<\/p>\n<p><strong class=\"sub-title\">Setting:\u00a0<\/strong>The Japan Gerontological Evaluation Study, a nationwide longitudinal cohort study, which ran from 2010 to 2016.<\/p>\n<p><strong class=\"sub-title\">Participants:\u00a0<\/strong>Functionally independent individuals who were older than 65 and had complete illness data at the time of baseline survey were eligible.<\/p>\n<p><strong class=\"sub-title\">Outcomes measure:\u00a0<\/strong>CMM was defined as the coexistence of 3 or more body system disorders at baseline. We calculated the propensity for each individual to develop CMM based on a wide array of characteristics, including socioeconomic status and health behaviours. Individuals with and without CMM were then matched on their propensity scores before we estimated overall survival using a log-rank test.<\/p>\n<p><strong class=\"sub-title\">Results:\u00a0<\/strong>Our 6-year follow-up included 38 889 older adults: 20 233 (52.0%) and 7565 (19.5%) adults with MM and CMM, respectively. In the MM-matched cohort (n=15 666 pairs), the presence of MM was significantly associated with increased mortality (HR 1.07; 95% CI 1.01 to 1.14; p=0.02 by the log-rank test). A similar mortality association was found in the CMM-matched cohort (n=7524 pairs, HR, 1.07; 95% CI 0.99 to 1.16; p=0.08 by the log-rank test).<\/p>\n<p><strong class=\"sub-title\">Conclusion:\u00a0<\/strong>This is the first study to report the association between CMM and mortality among older adults in Japan. MM and CMM predict mortality in older adults to a similar degree. This finding needs to be replicated with more precision in larger samples.<\/p>\n<\/div>\n<p><strong class=\"sub-title\">Keywords:\u00a0<\/strong>epidemiology; geriatric medicine; multimorbidity; social medicine.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>We published a study from BMJ Open. Kato D, Kawachi I, Saito J, Kondo N. Complex multimorbidity and mortality  &hellip; <a href=\"http:\/\/plaza.umin.ac.jp\/~naoki_kondo\/en\/blogs\/2452\" class=\"more-link\"><span class=\"screen-reader-text\">&#8220;Complex multimorbidity and mortality in Japan: a prospective propensity-matched cohort study.&#8221; \u306e<\/span>\u7d9a\u304d\u3092\u8aad\u3080<\/a><\/p>\n","protected":false},"author":3,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":[],"categories":[7],"tags":[],"_links":{"self":[{"href":"http:\/\/plaza.umin.ac.jp\/~naoki_kondo\/wp-json\/wp\/v2\/posts\/2452"}],"collection":[{"href":"http:\/\/plaza.umin.ac.jp\/~naoki_kondo\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"http:\/\/plaza.umin.ac.jp\/~naoki_kondo\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"http:\/\/plaza.umin.ac.jp\/~naoki_kondo\/wp-json\/wp\/v2\/users\/3"}],"replies":[{"embeddable":true,"href":"http:\/\/plaza.umin.ac.jp\/~naoki_kondo\/wp-json\/wp\/v2\/comments?post=2452"}],"version-history":[{"count":1,"href":"http:\/\/plaza.umin.ac.jp\/~naoki_kondo\/wp-json\/wp\/v2\/posts\/2452\/revisions"}],"predecessor-version":[{"id":2453,"href":"http:\/\/plaza.umin.ac.jp\/~naoki_kondo\/wp-json\/wp\/v2\/posts\/2452\/revisions\/2453"}],"wp:attachment":[{"href":"http:\/\/plaza.umin.ac.jp\/~naoki_kondo\/wp-json\/wp\/v2\/media?parent=2452"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"http:\/\/plaza.umin.ac.jp\/~naoki_kondo\/wp-json\/wp\/v2\/categories?post=2452"},{"taxonomy":"post_tag","embeddable":true,"href":"http:\/\/plaza.umin.ac.jp\/~naoki_kondo\/wp-json\/wp\/v2\/tags?post=2452"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}