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Positron Emission Tomography (PET)

 PETを用いた脳研究については、J Nippon Med Schの総説をご覧ください。

論文

M. Mishina, K. Ishii, M. Suzuki, S. Kitamura, K. Ishibashi, M. Sakata, K. Oda, M. Hamamoto, S. Kominami, S. Kobayashi, Y. Katayama, K. Ishiwata. Striatal Distribution of Dopamine Transporters and Dopamine D2 Receptors at Different Stages of Parkinson's Disease–A CFT and RAC PET Study. The Neuroradiology Journal 24(2), 235-241, April 2011

Mishina M, Ishiwata K, Naganawa M, Kimura Y, Kitamura S, Suzuki M, Hashimoto M, Ishibashi K, Oda K, Sakata M, Hamamoto M, Kobayashi S, Katayama Y, Ishii K: Adenosine A2A Receptors Measured with [11C]TMSX PET in the Striata of Parkinson's Disease Patients. PLoS One 6:e17338; 1-8, 2011.
 PLos ONEは全論文がOpen-accessのため、無料で論文のPDFがダウンロードできます。こちらから。別刷りの注文はこちらから。

三品雅洋:パーキンソン病。米倉義晴、伊藤正敏、窪田和雄、佐治英郎、玉木長良、中川恵一、畑澤 順、間賀田泰寛、渡辺恭良、寺田弘司編集、臨床医とコメディカルのための最新クリニカルPET、2010、pp184~187、先端医療技術研究所、東京 

三品雅洋:特集2 脳疾患の分子イメージング、パーキンソン病の分子イメージング。PET Journal No 10(summer), 34-35, 2010

Kiichi Ishiwata, Yuichi Kimura, Keiichi Oda, Kenji Ishii, Muneyuki Sakata, Keiichi Kawasaki, Tadashi Nariai, Yukihisa Suzuki, Kenji Ishibashi, Masahiro Mishina, Masaya Hashimoto, Masatomo Ishikawa and Jun Toyohara: Development of PET radiopharmaceuticals and their clinical applications at the Positron Medical Center. Geriatr Gerontol Int 10 (Suppl 1): S180–S196, 2010

Ohta Y, Nariai T, Ishii K, Ishiwata K, Mishina M, Senda M, Hirakawa K, Ohno K: Voxel- and ROI-based statistical analyses of PET parameters for guidance in the surgical treatment of intractable mesial temporal lobe epilepsy. Annals of Nuclear Medicine 22(6):495-503, 2008

Mishina M: Positron Emission Tomography for Brain Research. J Nippon Med Sch 75(2) 68-76, 2008

Amemiya S, Hamamoto M, Mishina M, Ueda M, Kumagai T, Nishiyama Y, Katayama Y: Short-term plasticity of central benzodiazepine receptors in status epilepticus: case report. Acta Neurol Scand 117(4) 285-8, 2008

Naganawa M, Kimura Y, Yano J, Mishina M, Yanagisawa M, Ishii K, Oda K, Ishiwata K: Robust estimation of the arterial input function for Logan plots using an intersectional searching algorithm and clustering in positron emission tomography for neuroreceptor imaging. Neuroimage40(1): 26-34, 2008

Kimura Y, Naganawa M, Sakata M, Ishikawa M, Mishina M, Oda K, Ishii K, Ishiwata K: Distribution volume as an alternative to the binding potential for sigma1 receptor imaging. Annals of Nuclear Medicine 21(9):533-5, 2007

Hashimoto M, Kawasaki K, Suzuki M, Mitani K, Murayama S, Mishina M, Oda K, Kimura Y, Ishiwata K, Ishii K, Inoue K: Presynaptic and postsynaptic nigrostriatal dopaminergic functions in multiple system atrophy. Neuroreport 19(2):145-150, 2008

三品雅洋、石井賢二、石渡喜一:アデノシン受容体―ドパミンとの関連―。臨床神経47(11)835-837、2007

三品雅洋:PETを用いた脳疾患の診断と病態の研究。日医大医会誌3(4) p220, 2007

石渡喜一、石井賢二、成相直、木村裕一、河村和紀、大山雅史、三品雅洋:脳シグマ受容体を指標とした加齢・神経変性疾患・脳腫瘍の新しいPET診断法。Innervision 19 (7):21、2004

Masahiro Mishina, Michio Senda, Motohiro Kiyosawa, Kiichi Ishiwata, Anne G. De Volder, Hideki Nakano, Hinako Toyama, Keiichi Oda, Yuichi Kimura, Kenji Ishii, Touru Sasaki, Masashi Ohyama, Yuichi Komaba, Shirou Kobayashi, Shin Kitamura, Yasuo Katayama. Increased Regional Cerebral Blood Flow but Normal Distribution of GABAA Receptor in Visual Cortex of Early Onset Blindness. NeuroImage 19 (1) 125-131, 2003

De Volder A. G., Toyama H., Kimura Y., Kiyosawa M., Nakano H., Vanlierde A., Wanet-Defalque M. C., Mishina M., Oda K., Ishiwata K. and Senda M: Auditory triggered mental imagery of shape involves visual association areas in early blind humans. Neuroimage 14 (1): 129-139, 2001.

三品雅洋、大山雅史、成相直、石井賢二、外山比南子、千田道雄、片山泰朗:PETを用いた脳神経細胞密度と脳血流の加齢変化の研究。老人病研究所紀要 10、8-10、2001

駒場祐一、三品雅洋、小林士郎、片山泰朗、寺本明:PET activationにて両側言語野を認めた脳粱無形成の一例。千葉核医学研究会誌 17 (2)、38-40、2001

Mishina M, Senda M, Kimura Y, Toyama H, Ishiwata K, Ohyama M, Nariai T, Ishii K, Oda K, Sasaki T, Kitamura S and Katayama Y: Intrasubject correlation between static scan and distribution volume images for [11C]flumazenil PET. Annals of Nuclear Medicine 14: 193-198, 2000

Kazunobu Ohmori, Shin-Ya Kuno, Yuichi Kimura, Masaki Mizuno, Yoshio Nakamura, Isao Muraoka, Fukio Ohta, Masahiro Mishina, Hinako Toyama and Michio Senda: Assessment of Regional Change of Glucose Metabolism after High-Intensity Exercise in Exercise Muscle using Positron Emission Tomography. Advanced Exercise Sports Physiology 6 (3) 81-84, 2000

Gondo Y, Shimonaka Y, Senda M, Mishina M and Toyama H: The role of prefrontal cortex in the GO / NO-GO task in humans. A PET study. Japanese Psychological Research 42, 36-44, 2000

Tatsumi IF, Senda M, Ishii K, Mishina M, Ohyama M, Toyama H, Oda K, Tanaka M and Gondo Y: Brain regions responsible for word retrieval, speech production and deficient word-fluency in elderly people: A PET activation study. Proceedings of ICSLP 2000 II: 5-10, 2000

Komaba Y, Senda M, Ohyama M, Mori T, Ishii K, Mishina M, Kitamura S, Terashi A: Bilateral representation of language function: Agenesis of corpus callosum by Wada and PET activation. Journal of Neuroimaging 8: 246-249, 1998

辰巳格、田中正之、千田道雄、三品雅洋、大山雅史、外山比南子:カテゴリー(固有名詞・生物・無生物)、音韻にもとづく単語の生成と、脳の活動部位。音声言語学 39(1)、63-64、1997

西山穣、坂本静樹、北村伸、片山泰朗、三品雅洋、赫彰郎:シアリドーシス成人発症例の脳循環代謝所見。臨床神経 37:982-986、1997