---- Previous Tokyo Area Worm Meetings ----
10 November 2007
Journal Club:
Hiroaki SAKANE (Department of Functional Genomics, Graduate School, Tokyo Medical and Dental University)
"Glia Promote Local Synaptogenesis Through UNC-6 (Netrin) Signaling in C. elegans."
Daniel A. Colon-Ramos, Milica A. Margeta, Kang Shen
Science 5 October 2007: Vol. 318. no. 5847, pp. 103 - 106.
Progress Report:
Takahiro KANAMORI (Dept. Health Chemistry, Grad. Schl. Pharm. Sci., Univ. Tokyo)
"Regulation of terminal asymmetric divisions of C. elegans epidermis by phospholipase A1 and retrograde traffic"
8 September 2007
Journal Club:
Jun TAKAYAMA (Molecular Genetics Research Lab., Univ. Tokyo)
"Dopamine Mediates Context-Dependent Modulation of Sensory Plasticity in C. elegans."
Neuron. 2007 Aug 16;55(4):662-76.
Kindt KS, Quast KB, Giles AC, De S, Hendrey D, Nicastro I, Rankin CH, Schafer WR.
Progress Report:
Tomoko FUJINO (Dept. Phys. Chem., Grad. Schl. Pharm. Sci., Univ. Tokyo)
"Lysosome-associated function of the small G protein Arl8"
16 June 2007
Journal Club:
Masahiro YAMASHITA
"Hierarchical assembly of presynaptic components in defined C. elegans synapses."
Nat Neurosci. 2006 Dec;9(12):1488-98.
Patel MR, Lehrman EK, Poon VY, Crump JG, Zhen M, Bargmann CI, Shen K.
Progress Report:
Sawako YOSHINA
"Novel regulatory mechanism of ER stress which involves protease"
24 March 2007
Journal Club:
Takeshi KARASHIMA (Dept. Biophys. Biochem., Grad. Schl. Sci., Univ. Tokyo)
"Translational regulators maintain totipotency in the Caenorhabditis elegans germline."
Ciosk R, DePalma M, Priess JR. Science. 2006 Feb 10;311(5762):851-3.
Progress Report:
Daisuke IKEDA (Molecular Genetics Research Lab., Univ. Tokyo)
"Functional analysis of CASY-1, a homologue of Calsyntenin/Alcadein, in chemotaxis learning in C. elegans"
3 February 2007
Journal Club:
Riyong PARK (Deptartment of Physiological Chemistry, Grad. Schl. Pharm. Sci., Univ. Tokyo)
"Serotonin targets the DAF-16/FOXO signaling pathway to modulate stress responses."
Cell Metabolism, Vol 4, 429-440
Bin Liang, Mustapha Moussaif, Chih-Jen Kuan, J. Jay Gargus, and Ji Ying Sze
Progress Report:
Tomoki KUWAHARA (Department of Neuropathology and Neuroscience, Univ. Tokyo)
"A genome-wide screen for factors modulating neurotoxicity of alpha-synuclein in transgenic C. elegans."
2 December 2006
Journal Club:
Naoko HARA (Dept. Health Chemistry, Grad. Schl. Pharm. Sci., Univ. Tokyo)
"A C. elegans Model of Nicotine-Dependent Behavior: Regulation by TRP-Family Channels."
Cell. 2006 Nov 3;127(3):621-33.
Feng Z, Li W, Ward A, Piggott BJ, Larkspur ER, Sternberg PW, Xu XZ.
Progress Report:
Genta OHNO (Department of Functional Genomics, Graduate School, Tokyo Medical and Dental University)
"Visualization of developmentally regulated alternative splicing events by a GFP/RFP based splicing reporter system"
9 September 2006
Journal Club:
Kotaro Kawamata (Department of Functional Genomics, Graduate School, Tokyo Medical and Dental University)
"Mutations That Increase the Life Span of C. elegans Inhibit Tumor Growth."
Science 18 August 2006: Vol. 313. no. 5789, pp. 971 - 975
Julie M. Pinkston, Delia Garigan, Malene Hansen, Cynthia Kenyon
Progress Report:
Daisuke TANAKA (Neuroscience Research Institute, AIST)
"Melatonin functions as a neuromodulator through the G-protein signaling in C. elegans"
1 July 2006
Journal Club:
Muneyoshi OTORI (School of Medicine, Tokyo Women's Medical University)
"C. elegans Dynamin Mediates the Signaling of Phagocytic Receptor CED-1 for the Engulfment and Degradation of Apoptotic Cells."
Yu X, Odera S, Chuang CH, Lu N, Zhou Z. Dev Cell. 2006 Jun;10(6):743-57.
Progress Report:
Masahiro Tomioka (Molecular Genetics Research Lab., Univ. Tokyo)
"Role of the Insulin/PI 3-kinase pathway in the salt chemotaxis learning in C. elegans"
13 May 2006
Journal Club:
Hiroyuki KOBUNA (Dept. Health Chemistry, Grad. Schl. Pharm. Sci., Univ. Tokyo)
"Identification of ligands for DAF-12 that govern dauer formation and reproduction in C. elegans." Cell. 2006 Mar 24;124(6):1209-23. Motola DL, Cummins CL, Rottiers V, Sharma KK, Li T, Li Y, Suino-Powell K, Xu HE, Auchus RJ, Antebi A, Mangelsdorf DJ.
Progress Report:
Hidehito KUROYANAGI (School of Biomedical Science, Tokyo Medical and Dental University)
"Construction of reporters for alternative splicing"
11 March 2006
Journal Club:
Genta Ohno (Dept. Functional Genomics, Tokyo Medical and Dental University)
"Functional Proteomics Reveals the Biochemical Niche of C. elegans DCR-1 in Multiple Small-RNA-Mediated Pathways" Duchaine et al., Cell (124) 343-354, 27 January 2006
Progress Report:
Naoko HARA & Rieko IMAE (Dept. Health Chemistry, Grad. Schl. Pharm. Sci., Univ. Tokyo)
"Novel acyltransferases that are involved in muscle and neuron function."
14 January 2006
Journal Club:
Masamitsu FUKUYAMA (Dept. Phys. Chem., Grad. Schl. Pharm. Sci., Univ. Tokyo)
"C. elegans tubby regulates life span and fat storage by two independent mechanisms"
Mukhopadhyay A, Deplancke B, Walhout AJ, Tissenbaum HA. Cell Metab. 2005 Jul;2(1):35-42.
Progress Report:
Eri HASEGAWA (Dept. Biophys. Biochem., Grad. Schl. Sci., Univ. Tokyo)
"Molecular genetic analysis of the RNA-binding protein CPB-3, which regulates multiple aspects of germline development in C. elegans"
12 November 2005
Journal Club:
Takahiro KANAMORI (Dept. Health Chemistry, Grad. Schl. Pharm. Sci., Univ. Tokyo)
"Cortical localization of the G protein GPA-16 requires RIC-8
function during C. elegansasymmetric cell division" Development 132, 4449-4459
Progress Report:
Kenji KONTANI (Dept. Phys. Chem., Grad. Schl. Pharm. Sci., Univ. Tokyo)
"A Vacuolar ATPase regulates developmental cell fusion in the embryonic epidermis."
10 September 2005
Journal Club:
Koji Yamada (Molecular Genetics Research Lab, Univ. Tokyo)
"Functional coordination of intraflagellar transport motors." Nature. 2005 Jul 28;436(7050):583-7.
Progress Report:
Ichiro KAWASAKI (Molecular Genetics Research Laboratory, the University of Tokyo)
"ASB-1, a germline-specific isoform of mitochondrial ATP synthase b subunit, functions as a pacemaker of C. elegans germline development"
9 July 2005
Journal Club:
Kohtaro KAWAMATA (Department of Functional Genomics, Graduate School, Tokyo Medical and Dental University)
"Functional Interaction Between B-Catenin and FOXO in Oxidative Stress Signaling" Science vol308 1181-1184 20 may 2005
Progress Report:
Tetsuo KOBAYASHI (Department of Physiology, Tokyo Women's Medical University School of Medicine)
"Functional analysis of the G-protein regulator AGS-3 in C. elegans"
15 May 2005
Journal Club:
Eri Hasegawa (Dept. Biophys. Biochem., Univ. Tokyo)
"RAS Is Regulated by the let-7 MicroRNA Family" Cell. 2005 March 11;120:635-647.
Progress Report:
Hirofumi Kunitomo (Molecular Genetics Research Lab., Univ. Tokyo)
"Genome-wide gene expression profiling of ciliated sensory neurons in C. elegans."
5 March 2005
Journal Club:
Keiko Gengyo-Ando (School of Medicine, Tokyo Women's Medical Universityj
"DRP-1-mediated mitochondrial fragmentation during EGL-1-induced cell death in C. elegans."
Nature. 2005 Feb 17;433(7027):754-60.
Progress Report:
Shoko Yoshimura (Biomedical Science PhD Program, Tokyo Medical and Dental University)
"CREB and the regulation of dauer formation"
15 January 2005
Journal Club:
Yosuke Matsubara (Department of Cell Regulation, Medical Research Institute, Tokyo Medical and Dental University)
"Extracellular proteins organize the mechanosensory channel complex in C. elegans touch receptor neurons."
Neuron. 2004 Dec 2;44(5):795-807.
Progress Report:
"Molecular genetic analysis of Na+ pump subunits involved in vesicular transport in C. elegans"
Motomichi Doi (Neuroscience Research Institute, National Institutes of Advanced and Industrial Sciences)
13 November 2004
Journal Club:
Kenji Sugioka (Dept. Biophys. Biochem., Univ. Tokyo)
"RIC-8 Is Required for GPR-1/2-Dependent Galpha Function during asymmetric Division of C. elegans Embryos."
Cell. 2004 Oct 15;119(2):219-30.
"RGS-7 Completes a Receptor-Independent Heterotrimeric G Protein Cycle to Asymmetrically Regulate Mitotic Spindle Positioning in C. elegans."
Cell. 2004 Oct 15;119(2):209-18.
Progress Report:
Masahiro Matsuki (Molecular Genetics Research Lab., Univ. Tokyo)
"Analysis of a G protein that regulates C. elegans olfactory response"
11 September 2004
Journal Club:
Daisuke Ikeda (Molecular Genetics Research Lab., Univ. Tokyo)
"A novel nuclear receptor/coregulator complex controls C. elegans lipid metabolism, larval development and aging."
Genes Dev. 2004 Aug 16 [Epub ahead of print]
Research Progress Report:
Yosuke Matsubara (Department of Cell Regulation, MRI, Tokyo Medical and Dental University)
"Analysis of rog-1, a novel signal transducer"
24 July 2004
Journal Club:
Mariko Sawa (Division of Biochemistry, Univ. Tokyo)
"Inhibition of netrin-mediated axon attraction by a receptor protein tyrosine phosphatase."
Science. 2004 Jul 2;305(5680):103-6.
Research Progress Report:
Tomoki Kuwahara (Deptartment of Neuropathology and Neuroscience, Graduate School of Pharmaceutical Sciences, Univ. Tokyo)
"Analysis of C. elegans transgenic strains that express alpha-synuclein in dopamine-neurons"
15 May 2004
Journal Club:
Yu Hayashi (Dept. Biology, Univ. Tokyo) "Conversion of cell movement responses to Semaphorin-1 and Plexin-1 from attraction to repulsion by lowered levels of specific RAC GTPases in C. elegans."
Development. 2004 May;131(9):2073-88
Research Progress Report:
"Analysis of mRNAs the C. elegans DAZ homolog binds in vivo."
Takeshi Karashima (Dept. Biophys. Biochem., Univ. Tokyo)
13 March 2004
Journal Club:
Muneyoshi Otori (Dept. Biophys. Biochem., Univ. Tokyo)
"The Lateral Signal for LIN-12/Notch in C. elegans Vulval Development Comprises Redundant Secreted and Transmembrane DSL Proteins."
Dev Cell. 2004 Feb;6(2):183-92.
Research Progress Report:
Takaaki Hirotsu (Molecular Genetics Research Lab., Univ. Tokyo)
"A mechanism of olfactory plasticity in C. elegans"
