〒173-8605 東京都板橋区加賀2-11-1
(内線 教授室46130、研究室45597)
2-11-1 Kaga, Itabashi, Tokyo 173-8605, Japan







Honap TP, Pfister L-A, Housman G, Mills S, Tarara RP, Suzuki K, Cuozzo FP, Sauther ML, Rosenberg MS, Stone AC. Mycobacterium leprae genomes from naturally infected nonhuman primates. PLoS Negl Trop Dis12(1): e0006190, 2018.

鈴木幸一:らい菌の感染、潜伏とハンセン病の発症までの背景。IASR 39(2), 2018.


Suzuki K and Luo Y. Chapter Four: Histone acetylation and the regulation of major histocompatibility class II gene expression. Donev R (Ed): Adv Protein Chem Struct Biol: Chromatin Remodelling and Immunity. Elsevier, Kidlington, Oxford UK, 106:71-111, 2017.

Oda K, Luo Y, Sekihata K, Usukura K, Yoshihara A, Sue M, Ishido Y, Hiroi N, Hirose T, Suzuki K. Follicular thyroglobulin (Tg) induces cathepsin H expression and activity in the thyrocytes. Biochem Biophys Res Commun 483(1): 541-546, 2017.

Kawashima A, Karasawa T, Tago K, Kimura H, Kamata R, Usui-Kawanishi F, Watanabe S, Ohta S, Funakoshi-Tago M, Yanagisawa K, Kasahara T, Suzuki K, Takahashi M. ARIH2 Ubiquitinates NLRP3 and Negatively Regulates NLRP3 Inflammasome Activation in Macrophages. J Immunol199(10):3614-3622, 2017.

鈴木幸一:皮膚感染症の報告−学会発表で賞を取り英文論文が採択されるための戦略−. J Visual Dermatol16: 132-138, 2017.


Luo Y, Sellitti DF and Suzuki K. The calpain proteolytic system. In: Bradshaw RA and Stahl PD (Eds): Encyclopedia of Cell Biology vol 1, Academic Press, Waltham, MA, 670-680, 2016.

Luo Y, Akama T, Okayama A, Yoshihara A, Sue M, Oda K, Hayashi M, Ishido Y, Hirano H, Hiroi N, Katoh R and Suzuki K. A novel role for flotillin-containing lipid rafts in negative-feedback regulation of thyroid-specific gene expression by thyroglobulin. Thyroid 26(11):1630-1639, 2016.

Luo Y, Yoshihara A, Oda K, Ishido Y, Hiroi N, Suzuki K. Naked DNA in cells: An inducer of major histocompatibility complex molecules to evoke autoimmune responses? World J Trans Med 5(1), 46-52, 2016.

Luo Y, Yoshihara A, Oda K, Ishido Y, Suzuki K. Excessive cytosolic DNA fragments as a potential trigger of Graves’ disease: An Encrypted Message Sent by Animal Models. Front Endocrinol 7, Article 144, 2016.

鈴木幸一、松村充。ハンセン病。一般社団法人日本臨床衛生検査技師会 監修、検体採取者のためのハンドブック (JAMT技術教本シリーズ)。じほう。71-74, 2016。


Luo Y, Hara T, Ishido Y, Yoshihara A, Oda K, Makino M, Ishii N, Hiroi N and Suzuki K. Rapid preparation of high-purity nuclear proteins from a small number of cultured cells for use in electrophoretic mobility shift assays. BMC Immunol 15:586, 2015.

Luo Y, Degang Y, Ohtsuka M, Ishido Y, Ishii N and Suzuki K. Detection of Mycobacterium ulcerans subsp. shinshuense DNA from a water channel in familial Buruli ulcer cases in Japan. Future Microbiol 10(2), 205-216, 2015.

Sugawara M, Ishii N, Nakanaga K, Suzuki K, Umebayashi Y, Makigami K, Aihara M. Exploration of a standard treatment for Buruli ulcer through a comprehensive analysis of all cases diagnosed in Japan. J Dermatol 42(6):588-95, 2015.

Niki M, Suzukawa M, Akashi S, Nagai H, Ohta K, Inoue M, Niki M, Kaneko Y, Morimoto K, Kurashima A, Kitada S, Matsumoto S, Suzuki K and Hoshino Y: Evaluation of humoral immunity to Mycobacterium tuberculosis-specific antigens for correlation with clinical status and effective vaccine development. J Immunol Res, ID 527395, 2015.

Ishido Y, Luo Y, Yoshihara A, Hayashi M, Yoshida A, Hisatome I and Suzuki K. Follicular thyroglobulin enhances gene expression necessary for thyroid hormone secretion. Endocrine J 62(11):1007-15, 2015.

Kimura H, Usui F, Karasawa T, Kawashima A, Shirasuna K, Inoue Y, Komada T, Kobayashi M, Mizushina Y, Kasahara T, Suzuki K, Iwasaki Y, Yada T, Caturegli P, Takahashi M. Immunoproteasome subunit LMP7 deficiency improves obesity and metabolic disorders. Sci Rep 5:15883, 2015.

Hoshino Y and Suzuki K. Differential diagnostic assays for discriminating mycobacteria, especially for non-tuberculosis mycobacteria: what does the future hold? Future Microbiol 10(2), 205-216, 2015.

Yotsu RR, Murase C, Sugawara M, Suzuki K, Nakanaga K, Ishii N, Asiedu K: Revisiting Buruli ulcer. J Dermatol 42, 1-9, 2015.

Kimura H, Caturegli P, Takahashi M, Suzuki K. New insights into the function of the immunoproteasome in immune and non-immune cells. J Immunol Res, ID 541984, 2015.


Suzuki K, Saso A, Hoshino K, Sakurai J, Tanigawa K, Luo Y, Ishido Y, Mori S, Hirata K and Ishii N. Paleopathological evidence and detection of Mycobacterium leprae DNA from archaeological skeletal remains of Nabe-kaburi (head-covered with iron pots) burials in Japan. PLoS ONE 9(2), e88356, 2014.

Sellitti DF and Suzuki K. Intrinsic Regulation of Thyroid Function by Thyroglobulin. Thyroid 24(4), 625-638, 2014..

Degang Y, Nakamura K, Akama T, Ishido Y, Luo Y, Ishii N and Suzuki K. Leprosy as a model of immunity. Future Microbiol 9(1), 43-54, 2014.

Ohtsuka M, Kikuchi N, Yamamoto T, Suzutani T, Nakanaga K, Suzuki K and Ishii N. Buruli ulcer caused by Mycobacterium ulcerans subsp. shinshuense: The first case of familial concurrent occurrence and detection of IS2404 from the environment in Japan. JAMA Dermatol 150(1), 64-67, 2014.

Nakamura T, Ito T, Uchida M, Hijioka M, Igarashi H, Oono T, Kato M, Nakamura K, Suzuki K, Jensen R and Takayanagi R. PSCs and GLP-1R: occurrence in normal pancreas, acute/chronic pancreatitis and effect of their activation by a GLP-1R agonist. Lab Invest 94(1), 63-78, 2014.

Nagai H, Suzukawa M, Sakakibara Y, Ohta K, Reche PA, Suzuki K and Hoshino Y. Immunological responses and epitope mapping by tuberculosis-associated antigens within the RD1 region in Japanese patients. J Immunol Res, ID764028, 2014.

Akama T, Luo Y, Sellitti DF, Kawashima A, Tanigawa K, Yoshihara A, Ishido Y, Nakamura K, Tanoue A, Suzuki K: Thyroglobulin increases thyroid cell proliferation via the suppression of specific microRNAs. Mol Endocrinol 28(3), 368-379, 2014.

Ishido Y, Yamazaki K, Kammori M, Sugishita Y, Luo Y, Yamada E, Yamada T, Sellitti DF, Suzuki K: Thyroglobulin suppresses thyroid-specific gene expression in cultures of normal but not neoplastic human thyroid follicular cells. J Clin Endocrinol Metab 99(4), E694-702, 2014.

Uchida M, Ito T, Nakamura T, Hijioka M, Igarashi H, Oono T, Kato M, Nakamura K, Suzuki K, Takayanagi R, Jensen RT: Pancreatic stellate cells and CX3CR1: occurrence in normal pancreas and acute and chronic pancreatitis and effect of their activation by a CX3CR1 agonist. Pancreas 43(5), 708-719, 2014.

Matsumoto T, Suzuki M, Iinuma Y, Maeda S, Ano H, Koshi Y, Murakawa T, Suzuki K and Hoshino Y. A molecular typing methodology of Mycobacterium tuberculosis using small genomic islet patterns (TB-SGIP): a novel genotyping methodology to discriminate clinical strains between Beijing family and T3-OSAKA. J Infect Dis Ther 2:35-45, 2014.

Luo Y, Ishido Y, Hiroi N, Ishii N and Suzuki K. The emerging roles of thyroglobulin. Advances in Endocrinology 2014, 189194, 2014.

Luo Y, Kawashima A, Ishido Y, Yoshihara A, Oda K, Hiroi N, Ito T, Ishii N and Suzuki K. Iodine excess as an environmental risk factor for autoimmune thyroid disease. Int J Mol Sci 15, 12895-12912, 2014.

Lee L, Ito T, Hijioka M, Igarashi H, Ueda K, Fujiyama T, Tachibana Y, Kawabe K, Jensen RT, Nakamura K, Kato M, Suzuki K, Takayanagi R. Current management of type 1 autoimmune pancreatitis: From the viewpoint of pancreatic endocrine and exocrine function. Autoimmune Dis Ther Approach 1:2, 2014.

Yuqian Luo、鈴木幸一: 甲状腺の疾患と生理機能に関わるmicroRNA. ホルモンと臨床 61(1),75-80, 2014.


Uchida M, Ito T, Nakamura T, Igarashi H, Oono T, Fujimori N, Kawabe K, Suzuki K, Jensen RT, Takayanagi R: ERK pathway and sheddases play an essential role in ethanol-induced CX3CL1 release in pancreatic stellate cells. Lab Invest 93(1), 41-53, 2013.

Yamagata K, Nakayama C, Suzuki K: Dietary beta-carotene regulates interleukin-1beta-induced expression of apolipoprotein E in astrocytes isolated from stroke-prone spontaneously hypertensive rats. Neurochem Int 62(1), 43-49, 2013.

Yamagata K, Tanaka N, Suzuki K: Epigallocatechin 3-gallate inhibits 7-ketocholesterol-induced monocyte-endothelial cell adhesion. Microvasc Res 88, 25-31, 2013.

Kawashima A, Yamazaki K, Hara T, Akama T, Yoshihara A, Sue M, Tanigawa K, Wu H, Ishido Y, Takeshita F, Ishii N, Sato K, Suzuki K: Demonstration of innate immune responses in the thyroid gland: potential to sense danger and a possible trigger for autoimmune reactions. Thyroid 23(4), 477-487, 2013.

Matsumoto T, Hirayama Y, Hisamitsu Y, Fukumura M, Hirata A, Tanaka K, Kurokawa M, Tamura Y, Yoshida H, Nagai T, Kawase I, Suzuki K and Hoshino Y. Simultaneous and longitudinal comparison of interferon gamma release assay data from health care workers in Japan. J Mycobac Dis 2(3), 1000134, 2013.

Akama T, Kawashima A, Tanigawa K, Hayashi M, Ishido Y, Luo Y, Hata A, Fujitani N, Ishii N and Suzuki K. Comprehensive analysis of prokaryotes in environmental water using DNA microarray analysis and whole genome amplification. Pathogens 2, 591-605, 2013.

Kobiyama K, Kawashima A, Jounai N, Takeshita F, Ishii KJ, Ito T, Suzuki K: Role of extrachromosomal histone H2B on recognition of DNA viruses and cell damage. Front Genet 4, 91, 2013.

Nakanaga K, Yotsu RR, Hoshino Y, Suzuki K, Makino M, Ishii N: Buruli ulcer and mycolactone-producing mycobacteria. Jpn J Infect Dis 66(2), 83-88, 2013.

Akama T, Nakamura K, Tanoue A and Suzuki K. Design of tiling arrays and their application to bacterial transcriptome analysis. In: Lee T-L (Eds): Tiling Arrays: Methods and Protocols. Humana Press, NY, 23-34, 2013.

木村 博昭, 鈴木 幸一: 【甲状腺機能異常症-橋本病発見より100周年】 橋本病における遺伝子発現異常と病態. カレントテラピー 31(1), 71-75, 2013.

木村 博昭, 鈴木 幸一: 肉芽腫 -免疫を中心に-. Monthly Book Derma 204:8-14, 2013.

森 修一, スマナ・バルア, 鈴木 幸一, 四津 里英, 石井 則久: 2012年における世界のハンセン病の現況について. 日本ハンセン病学会雑誌 82(1-2), 59-69, 2013.

鈴木 幸一, 木村 博昭: 橋本病の病因. 日本甲状腺学会雑誌 4(1), 14-18, 2013.

鈴木 幸一: 損傷細胞由来DNAと自己免疫疾患. 臨床免疫・アレルギー科 60(3):247-257, 2013.


Suzuki K, Akama T, Kawashima A, Yoshihara A, Yotsu RR, Ishii N: Current status of leprosy: epidemiology, basic science and clinical perspectives. J Dermatol 39(2), 121-129, 2012. (Most cited paper 2014 Impact Factor period)

Tanigawa K, Degang Y, Kawashima A, Akama T, Yoshihara A, Ishido Y, Makino M, Ishii N, Suzuki K: Essential role of hormone-sensitive lipase (HSL) in the maintenance of lipid storage in Mycobacterium leprae-infected macrophages. Microb Pathog 52(5), 285-291, 2012.

Degang Y, Akama T, Hara T, Tanigawa K, Ishido Y, Gidoh M, Makino M, Ishii N, Suzuki K: Clofazimine modulates the expression of lipid metabolism proteins in Mycobacterium leprae-infected macrophages. PLoS Negl Trop Dis 6(12), e1936, 2012.

Mori S, Yotsu RR, Suzuki K, Makino M, Ishii N: Present situation of leprosy in Japan, 2006-2010: analysis of drug resistance in new registered and relapsed cases by molecular biological methods. J Dermatol Sci 67(3), 192-194, 2012.

Nakamura T, Ito T, Igarashi H, Uchida M, Hijioka M, Oono T, Fujimori N, Niina Y, Suzuki K, Jensen RT, Takayanagi R: Cytosolic double-stranded DNA as a damage-associated molecular pattern induces the inflammatory response in rat pancreatic stellate cells: a plausible mechanism for tissue injury-associated pancreatitis. Int J Inflam 2012, 504128, 2012.

Akama T, Sue M, Kawashima A, Wu H, Tanigawa K, Suzuki S, Hayashi M, Yoshihara A, Ishido Y, Ishii N, Suzuki K: Identification of microRNAs that mediate thyroid cell growth induced by TSH. Mol Endocrinol 26(3), 493-501, 2012.

Sue M, Akama T, Kawashima A, Nakamura H, Hara T, Tanigawa K, Wu H, Yoshihara A, Ishido Y, Hiroi N, Yoshino G, Kohn LD, Ishii N, Suzuki K: Propylthiouracil increases sodium/iodide symporter gene expression and iodide uptake in rat thyroid cells in the absence of TSH. Thyroid 22(8), 844-852, 2012.

Sue M, Hayashi M, Kawashima A, Akama T, Tanigawa K, Yoshihara A, Hara T, Ishido Y, Ito T, Takahashi S, Ishii N, Suzuki K: Thyroglobulin (Tg) activates MAPK pathway to induce thyroid cell growth in the absence of TSH, insulin and serum. Biochem Biophys Res Commun 420(3), 611-615, 2012.

Yamanaka D, Akama T, Fukushima T, Nedachi T, Kawasaki C, Chida K, Minami S, Suzuki K, Hakuno F, Takahashi S: Phosphatidylinositol 3-kinase-binding protein, PI3KAP/XB130, is required for cAMP-induced amplification of IGF mitogenic activity in FRTL-5 thyroid cells. Mol Endocrinol 26(6), 1043-1055, 2012.

Yoshihara A, Hara T, Kawashima A, Akama T, Tanigawa K, Wu H, Sue M, Ishido Y, Hiroi N, Ishii N, Yoshino G, Suzuki K: Regulation of dual oxidase (DUOX) expression and H2O2 production by thyroglobulin. Thyroid 22(10),1054-62, 2012.

Yotsu RR, Nakanaga K, Hoshino Y, Suzuki K, Ishii N: Buruli ulcer and current situation in Japan: a new emerging cutaneous Mycobacterium infection. J Dermatol 39(7), 587-593, 2012.

森 修一, スマナ・バルア, 鈴木 幸一, 石井 則久, 四津 里英: 2011年における世界のハンセン病の現況について. 日本ハンセン病学会雑誌 81(1-2), 145-154, 2012.

鈴木 幸一, 川島 晃, 木村 博昭: 【甲状腺疾患-診断・治療の最新動向-】 病因および疾患関連遺伝子 自己免疫性甲状腺疾患の病因・病態解明研究の最新動向. 日本臨床 70(11), 1880-1884, 2012.

鈴木 幸一, 赤間 剛: ブルーリ潰瘍の感染経路、自然宿主について. IASR 33, 90-91, 2012.


Suzuki K, Tanigawa K, Kawashima A, Miyamura T, Ishii N: Chimpanzees used for medical research shed light on the pathoetiology of leprosy. Future Microbiol 6(10), 1151-1157, 2011.

Suzuki K, Kawashima A, Yoshihara A, Akama T, Sue M, Yoshida A, Kimura HJ: Role of thyroglobulin on negative feedback autoregulation of thyroid follicular function and growth. J Endocrinol 209(2), 169-174, 2011.

Kawashima A, Tanigawa K, Akama T, Wu H, Sue M, Yoshihara A, Ishido Y, Kobiyama K, Takeshita F, Ishii KJ, Hirano H, Kimura H, Sakai T, Ishii N, Suzuki K: Fragments of genomic DNA released by injured cells activate innate immunity and suppress endocrine function in the thyroid. Endocrinology 152(4), 1702-1712, 2011.

Nakamura T, Ito T, Oono T, Igarashi H, Fujimori N, Uchida M, Niina Y, Yasuda M, Suzuki K, Takayanagi R: Bacterial DNA promotes proliferation of rat pancreatic stellate cells thorough toll-like receptor 9: potential mechanisms for bacterially induced fibrosis. Pancreas 40(6), 823-831, 2011.

Igarashi H, Fujimori N, Ito T, Nakamura T, Oono T, Nakamura K, Suzuki K, Jensen RT, Takayanagi R: Vasoactive intestinal peptide (VIP) and VIP Receptors -Elucidation of Structure and Function for Therapeutic Applications. Int J Clin Med 2(4), 500-508, 2011.

Kawashima A, Tanigawa K, Akama T, Yoshihara A, Ishii N, Suzuki K: Innate immune activation and thyroid autoimmunity. J Clin Endocrinol Metab 96(12), 3661-3671, 2011.

Kimura HJ, Suzuki K, Landek-Salgado MA, Caturegli P, Jounai N, Kobiyama K, Takeshita F: Application of innate immune molecules for a new class of drugs: infection, inflammation and beyond. Endocr Metab Immune Disord Drug Targets 11(1), 68-75, 2011.

Akama T, Tanigawa K, Nakamura K, Kawashima A, Wu H, Sue M, Yoshihara A, Ishido Y, Ishii N and Suzuki K. Whole Genome Tiling Array Analysis of Bacterial Genome. In: Campbell MJ (Eds): DNA Microarrays, Synthesis and Synthetic DNA. Nova Science Publishers, Hauppauge, NY, 301-315, 2011.

Ishii N, Nagaoka Y, Mori S and Suzuki K. Hansen’s disease in Asia. In: Eun HC, Kim S-C, Lee W-S (Eds): Asian Skin and Skin Diseases, Medrang Inc, Seoul, 335-342, 2011

四津 里英,鈴木 幸一,森 修一,石井則久: ハンセン病の診断. 日本ハンセン病学会誌 80, 59-70, 2011.

森 修一, 鈴木 幸一, スマナ・バルア, 石井 則久: 2010年における世界のハンセン病の現況について. 日本ハンセン病学会雑誌 80, 37-46, 2011.

石井 則久, 鵜殿 俊史, 藤澤 道子, 伊谷 原一, 谷川 和也, 宮村 達男, 鈴木 幸一: チンパンジーとハンセン病. 日本ハンセン病学会雑誌 80(1), 29-36, 2011.

鈴木 幸一: 「ハンセン病は遺伝病」ではない. 日本ハンセン病学会誌 80, 244, 2011.

鈴木 幸一: 遺跡発掘と感染症の可能性. 日本医事新報 (4550), 62-63, 2011.

鈴木 幸一, 川島 晃: 【甲状腺疾患 最新のガイドラインと知見を用いたこれからの実地診療】 セミナー/最新のガイドラインに基づいた実地診療 自己免疫性甲状腺疾患発症の免疫学的機序の基礎と最近の進歩. Medical Practice 28(11), 1950-1954, 2011.


Suzuki K, Takigawa W, Tanigawa K, Nakamura K, Ishido Y, Kawashima A, Wu H, Akama T, Sue M, Yoshihara A, Mori S, Ishii N: Detection of Mycobacterium leprae DNA from archaeological skeletal remains in Japan using whole genome amplification and polymerase chain reaction. PLoS One 5(8), e12422, 2010.

Suzuki K, Udono T, Fujisawa M, Tanigawa K, Idani G, Ishii N: Infection during infancy and long incubation period of leprosy suggested in a case of a chimpanzee used for medical research. J Clin Microbiol 48(9), 3432-3434, 2010.

Suzuki K, Kimura H, Wu H, Kudo N, Kim WB, Suzuki S, Yoshida A, Caturegli P, Kohn LD: Excess iodide decreases transcription of NIS and VEGF genes in rat FRTL-5 thyroid cells. Biochem Biophys Res Commun 393(2), 286-290, 2010.

Akama T, Tanigawa K, Kawashima A, Wu H, Ishii N, Suzuki K: Analysis of Mycobacterium leprae gene expression using DNA microarray. Microb Pathog 49(4), 181-185, 2010.

Kobiyama K, Takeshita F, Jounai N, Sakaue-Sawano A, Miyawaki A, Ishii KJ, Kawai T, Sasaki S, Hirano H, Ishii N, Okuda K, Suzuki K: Extrachromosomal histone H2B mediates innate antiviral immune responses induced by intracellular double-stranded DNA. J Virol 84(2), 822-832, 2010.

Noguchi Y, Harii N, Giuliani C, Tatsuno I, Suzuki K, Kohn LD: Thyroglobulin (Tg) induces thyroid cell growth in a concentration-specific manner by a mechanism other than thyrotropin/cAMP stimulation. Biochem Biophys Res Commun 391(1), 890-894, 2010.

Yamazaki K, Tanigawa K, Suzuki K, Yamada E, Yamada T, Takano K, Obara T, Sato K: Iodide-induced chemokines and genes related to immunological function in cultured human thyroid follicles in the presence of thyrotropin. Thyroid 20(1), 67-76, 2010.

Akama T, Suzuki K, Tanigawa K, Nakamura K, Kawashima A, Wu H, Sue M, Yoshihara A, Ishido Y, Ishii N: Whole-genome expression analysis of Mycobacterium leprae and its clinical application. Jpn J Infect Dis 63(6), 387-392, 2010.

Kobiyama K, Jounai N, Ishii KJ, Horii T, Suzuki K, Ryo A, Takeshita F: Modulation of intracellular signaling using protein-transduction technology. Crit Rev Immunol 30(5), 395-421, 2010.

森 修一, 鈴木 幸一, スマナ・バルア, 永岡 譲, 石井 則久: ハンセン病による負荷のさらなる軽減のための強化された世界戦略. 日本ハンセン病学会雑誌 79(1), 53-73, 2010.

石井 則久, スマナ・バルア, 森 修一, 永岡 譲, 鈴木 幸一: WHO第10回ハンセン病制圧のための技術勧告(Technical Advisory Group:TAG)会議報告書. 日本ハンセン病学会雑誌 79(1), 37-42, 2010.

鈴木 幸一, 森 修一, 永岡 譲, 石井 則久: 2009年における世界のハンセン病の現況について. 日本ハンセン病学会雑誌 79(1), 43-51, 2010.


Akama T, Suzuki K, Tanigawa K, Kawashima A, Wu H, Nakata N, Osana Y, Sakakibara Y, Ishii N: Whole-genome tiling array analysis of Mycobacterium leprae RNA reveals high expression of pseudogenes and noncoding regions. J Bacteriol 191(10), 3321-3327, 2009.

Tanigawa K, Suzuki K, Kimura H, Takeshita F, Wu H, Akama T, Kawashima A, Ishii N: Tryptophan aspartate-containing coat protein (CORO1A) suppresses Toll-like receptor signalling in Mycobacterium leprae infection. Clin Exp Immunol 156(3), 495-501, 2009.

Nakamura K, Akama T, Bang PD, Sekimura S, Tanigawa K, Wu H, Kawashima A, Hayashi M, Suzuki K, Ishii N: Detection of RNA expression from pseudogenes and non-coding genomic regions of Mycobacterium leprae. Microb Pathog 47(3), 183-187, 2009.

Kobiyama K, Takeshita F, Ishii KJ, Koyama S, Aoshi T, Akira S, Sakaue-Sawano A, Miyawaki A, Yamanaka Y, Hirano H, Suzuki K, Okuda K: A signaling polypeptide derived from an innate immune adaptor molecule can be harnessed as a new class of vaccine adjuvant. J Immunol 182(3), 1593-1601, 2009.

Bang PD, Suzuki K, Phuong Le T, Chu TM, Ishii N, Khang TH: Evaluation of polymerase chain reaction-based detection of Mycobacterium leprae for the diagnosis of leprosy. J Dermatol 36(5), 269-276, 2009.

Kimura HJ, Chen CY, Tzou SC, Rocchi R, Landek-Salgado MA, Suzuki K, Kimura M, Rose NR, Caturegli P: Immunoproteasome overexpression underlies the pathogenesis of thyroid oncocytes and primary hypothyroidism: studies in humans and mice. PLoS One 4(11), e7857, 2009.

Chen CY, Kimura H, Landek-Salgado MA, Hagedorn J, Kimura M, Suzuki K, Westra W, Rose NR, Caturegli P: Regenerative potentials of the murine thyroid in experimental autoimmune thyroiditis: role of CD24. Endocrinology 150(1), 492-499, 2009.

Kimura HJ, Rocchi R, Landek-Salgado MA, Suzuki K, Chen CY, Kimura M, Rose NR, Caturegli P: Influence of signal transducer and activator of transcription-1 signaling on thyroid morphology and function. Endocrinology 150(7), 3409-3416, 2009.

Wu H, Suzuki S, Sellitti DF, Doi SQ, Tanigawa K, Aizawa S, Akama T, Kawashima A, Mishima M, Ishii N, Yoshida A, Hisatome I, Koles NL, Katoh R, Suzuki K: Expression of a thyroglobulin (Tg) variant in mouse kidney glomerulus. Biochem Biophys Res Commun 389(2), 269-273, 2009.

Yoshida A, Hisatome I, Taniguchi S, Shirayoshi Y, Yamamoto Y, Miake J, Ohkura T, Akama T, Igawa O, Shigemasa C, Kamijo K, Ikuyama S, Caturegli P, Suzuki K: Pendrin is a novel autoantigen recognized by patients with autoimmune thyroid diseases. J Clin Endocrinol Metab 94(2), 442-448, 2009.

永岡 譲, 石田 裕, 鈴木 幸一, 石井 則久: ミャンマーにおけるハンセン病制圧記念行事(2009)の報告. 日本ハンセン病学会雑誌 78(3), 251-253, 2009.

石井 則久, 森 修一, 永岡 譲, 鈴木 幸一: WHO第9回ハンセン病制圧のための技術勧告(Technical Advisory Group:TAG)会議報告. 日本ハンセン病学会雑誌 78(1), 75-88, 2009.

石井 則久, 鈴木 幸一: 地球温暖化に伴う輸入感染症. 皮膚科の臨床 51(1), 7-11, 2009.

石井 則久, 鈴木 幸一: 抗酸菌感染症. 皮膚科の臨床 51(1), 1599-1606, 2009.

赤間 剛, 鈴木 幸一, 谷川 和, 川島 晃, Wu H, 中村 和, 林 も, 石井 則久: タイリングアレイを用いたらい菌全ゲノムにおける発現部位の検出. 日本ハンセン病学会雑誌 78(1), 49-54, 2009.

鈴木 幸一, 中村 和, 谷川 和, 川島 晃, Wu H, 赤間 剛, 林 も, 関村 慎, Pham DB, 石井 則久: らい菌ゲノム由来RNA発現の網羅的解析とその意味するもの. 日本ハンセン病学会雑誌 78(1), 61-65, 2009.

鈴木 幸一, 永岡 譲, 森 修一, 石井 則久: 2008年における世界のハンセン病の現況について. 日本ハンセン病学会雑誌 78(1), 25-34, 2009.


Tanigawa K, Suzuki K, Nakamura K, Akama T, Kawashima A, Wu H, Hayashi M, Takahashi S, Ikuyama S, Ito T, Ishii N: Expression of adipose differentiation-related protein (ADRP) and perilipin in macrophages infected with Mycobacterium leprae. FEMS Microbiol Lett 289(1), 72-79, 2008.

Kyaw K, Tsoh TM, Swe SY, Nagaoka Y, Takezaki S, Suzuki K, Ishii N: Clinical analysis of multibacillary leprosy patients after 1-year fixed World Health Organization recommended multidrug therapy at Yangon General Hospital, Myanmar. J Dermatol 35(5), 264-269, 2008.

Nakao I, Kanaji S, Ohta S, Matsushita H, Arima K, Yuyama N, Yamaya M, Nakayama K, Kubo H, Watanabe M, Sagara H, Sugiyama K, Tanaka H, Toda S, Hayashi H, Inoue H, Hoshino T, Shiraki A, Inoue M, Suzuki K, Aizawa H, Okinami S, Nagai H, Hasegawa M, Fukuda T, Green ED, Izuhara K: Identification of pendrin as a common mediator for mucus production in bronchial asthma and chronic obstructive pulmonary disease. J Immunol 180(9), 6262-6269, 2008.

Ishibashi T, Zhao H, Kawabe K, Oono T, Egashira K, Suzuki K, Nawata H, Takayanagi R, Ito T: Blocking of monocyte chemoattractant protein-1 (MCP-1) activity attenuates the severity of acute pancreatitis in rats. J Gastroenterol 43(1), 79-85, 2008.

山本 晃三,種瀬 啓士,原藤 玲,宮川 俊一,石井 則久,鈴木 幸一: らい反応を呈したHansen病の1例 らい反応治療と免疫再構築症候群の関連を含めて. 臨床皮膚科 62(13), 1012-1015, 2008.

Bang PD, Suzuki K, Ishii N, Khang TH: Leprosy situation in Vietnam--reduced burden of stigma. Nihon Hansenbyo Gakkai Zasshi 77(1), 29-36, 2008.

與儀 ヤス子, 藤村 響男, 鈴木 幸一: ハンセン病動物モデルの歴史と高血圧ヌードラットの特徴. 日本ハンセン病学会雑誌 77(3), 197-204, 2008.
谷川 和, 鈴木 幸一, 川島 晃, 三島 眞, Wu H, 赤間 剛, 武下 文, 石井 則久: らい菌感染マクロファージにおける細胞内寄生と排除に関わる分子機構. 日本ハンセン病学会雑誌 77(1), 57-61, 2008.

鈴木 幸一, 永岡 譲, 森 修一, 石井 則久: 2007年における世界のハンセン病の現況について. 日本ハンセン病学会雑誌 77(1), 15-23, 2008.

鈴木 幸一, 赤間 剛, 石井 則久: ハンセン病 Neglected Diseasesのコントロールに向けて ハンセン病研究の基礎と臨床の架け橋 らい菌ゲノム発現情報の臨床応用. 日本皮膚科学会雑誌 118(13), 2783, 2008.


Jounai N, Takeshita F, Kobiyama K, Sawano A, Miyawaki A, Xin KQ, Ishii KJ, Kawai T, Akira S, Suzuki K, Okuda K: The Atg5 Atg12 conjugate associates with innate antiviral immune responses. Proc Natl Acad Sci U S A 104(35), 14050-14055, 2007.

Rocchi R, Kimura H, Tzou SC, Suzuki K, Rose NR, Pinchera A, Ladenson PW, Caturegli P: Toll-like receptor-MyD88 and Fc receptor pathways of mast cells mediate the thyroid dysfunctions observed during nonthyroidal illness. Proc Natl Acad Sci U S A 104(14), 6019-6024, 2007.

Nakanaga K, Ishii N, Suzuki K, Tanigawa K, Goto M, Okabe T, Imada H, Kodama A, Iwamoto T, Takahashi H, Saito H: "Mycobacterium ulcerans subsp. shinshuense" isolated from a skin ulcer lesion: identification based on 16S rRNA gene sequencing. J Clin Microbiol 45(11), 3840-3843, 2007.

Sellitti DF, Puggina E, Lagranha C, Doi SQ, Pithon-Curi T, Kohn LD, Suzuki K: TGF-beta-like transcriptional effects of thyroglobulin (Tg) in mouse mesangial cells. Endocr J 54(3), 449-458, 2007.

Yamazaki K, Suzuki K, Yamada E, Yamada T, Takeshita F, Matsumoto M, Mitsuhashi T, Obara T, Takano K, Sato K: Suppression of iodide uptake and thyroid hormone synthesis with stimulation of the type I interferon system by double-stranded RNA (dsRNA) in cultured human thyroid follicles. Endocrinology 148(7), 3226-3235, 2007.

石井 則久, 鈴木 幸一, 竹崎 伸一郎, 永岡 譲: 皮膚スメア検査のアンケート調査結果. 日本ハンセン病学会雑誌 76(3), 227-232, 2007.

鈴木 幸一.21世紀の甲状腺基礎医学研究への展望.日本甲状腺学会理事会・広報委員会編,21世紀の甲状腺診療・研究への展望,メディカルレビュー社,90-91,2007.

Kohn LD, Suzuki K, Mori A, Ishii JK, Klinman DM. Immune activation of double strand polynucleotides. Australian Patent 2004201249 September 2007.


Suzuki K, Nakata N, Bang PD, Ishii N, Makino M: High-level expression of pseudogenes in Mycobacterium leprae. FEMS Microbiol Lett 259(2), 208-214, 2006.

Suzuki K, Takeshita F, Nakata N, Ishii N, Makino M: Localization of CORO1A in the Macrophages Containing Mycobacterium leprae. Acta Histochem Cytochem 39(4), 107-112, 2006.

Suzuki K, Kohn LD: Differential regulation of apical and basal iodide transporters in the thyroid by thyroglobulin. J Endocrinol 189(2), 247-255, 2006.

Ishii KJ, Coban C, Kato H, Takahashi K, Torii Y, Takeshita F, Ludwig H, Sutter G, Suzuki K, Hemmi H, Sato S, Yamamoto M, Uematsu S, Kawai T, Takeuchi O, Akira S: A Toll-like receptor-independent antiviral response induced by double-stranded B-form DNA. Nat Immunol 7(1), 40-48, 2006.

Takeshita F, Tanaka T, Matsuda T, Tozuka M, Kobiyama K, Saha S, Matsui K, Ishii KJ, Coban C, Akira S, Ishii N, Suzuki K, Klinman DM, Okuda K, Sasaki S: Toll-like receptor adaptor molecules enhance DNA-raised adaptive immune responses against influenza and tumors through activation of innate immunity. J Virol 80(13), 6218-6224, 2006.

石井 則久, 中永 和枝, 松岡 正典, 鈴木 幸一: らい菌の遺伝子診断の現状. 日本ハンセン病学会雑誌 75(3), 261-264, 2006.

石井 則久, 森 修一, 鈴木 幸一: 世界のハンセン病の現況. 日本ハンセン病学会雑誌 75(1), 41-49, 2006.

石井 則久, 永岡 譲, 森 修一, 鈴木 幸一: ハンセン病制圧後のハンセン病対策戦略. 日本ハンセン病学会雑誌 75(3), 239-248, 2006.

石井 則久, 鈴木 幸一, 朝比奈 昭: 【知っておきたい検査とその読み方】 感染症の検査 新たな結核検査 クォンティフェロンTB-2G. 皮膚科の臨床 48(10), 1377-1380, 2006.

鈴木 幸一, 吉田 明雄, 深田 修司: 【内分泌症候群 その他の内分泌疾患を含めて】 甲状腺 甲状腺機能低下症 先天性甲状腺ホルモン合成障害 Pendred症候群. 日本臨床 別冊(内分泌症候群I), 371-373, 2006.

鈴木 幸一, 森 修一, 石井 則久: 世界のハンセン病の将来戦略. 日本ハンセン病学会雑誌 75(1), 23-39, 2006.

鈴木 幸一, 石井 則久: 【知っておきたい検査とその読み方】 感染症の検査 抗酸菌検査. 皮膚科の臨床 48(10), 1371-1375, 2006.


Takeshita F, Ishii KJ, Kobiyama K, Kojima Y, Coban C, Sasaki S, Ishii N, Klinman DM, Okuda K, Akira S, Suzuki K: TRAF4 acts as a silencer in TLR-mediated signaling through the association with TRAF6 and TRIF. Eur J Immunol 35(8), 2477-2485, 2005.

Kimura H, Kimura M, Tzou SC, Chen YC, Suzuki K, Rose NR, Caturegli P: Expression of class II major histocompatibility complex molecules on thyrocytes does not cause spontaneous thyroiditis but mildly increases its severity after immunization. Endocrinology 146(3), 1154-1162, 2005.

Kimura H, Tzou SC, Rocchi R, Kimura M, Suzuki K, Parlow AF, Rose NR, Caturegli P: Interleukin (IL)-12-driven primary hypothyroidism: the contrasting roles of two Th1 cytokines (IL-12 and interferon-gamma). Endocrinology 146(8), 3642-3651, 2005.

吉田 明雄,谷口 晋一,福井 裕子,岡村 僚久,清水 秀樹,大倉 毅,重政 千秋,久留 一郎,鈴木 幸一,谷山 松雄: 【分子甲状腺学の進歩2005】 ペンドレット症候群の病態の解明とペンドリンの生理学的役割. ホルモンと臨床 53(1), 37-41, 2005.

木村 博昭, 木村 美穂, Caturegli P, 鈴木 幸一: 【分子甲状腺学の進歩2005】 自己免疫動物モデルによる甲状腺免疫学の進歩. ホルモンと臨床 53(1), 67-74, 2005.

牧野 正彦,鈴木 幸一,福富 康夫,山下 康子,前田 百美,宮本 友司,向井 徹,中田 登,甲斐 雅規,山崎 利雄,儀同 政一,松岡 正典: ハンセン病基礎医学研究のトピックス. 日本ハンセン病学会雑誌 74(1), 3-22, 2005.

鈴木 幸一, 吉田 明雄: 【臨床分子内分泌学 甲状腺・副甲状腺・骨内分泌代謝系】 甲状腺ホルモン 基礎研究の進展 Na/Iシンポーター遺伝子とPDS遺伝子. 日本臨床 63(増刊10 臨床分子内分泌学(3)), 20-23, 2005.

Kohn LD, Suzuki K, Mori A, Ishii JK, Klinman DM, Rice JM. Immune activation of double strand polynucleotides. United States Patent 20050036993, December 17, 2005.


Takeshita F, Gursel I, Ishii KJ, Suzuki K, Gursel M, Klinman DM: Signal transduction pathways mediated by the interaction of CpG DNA with Toll-like receptor 9. Semin Immunol 16(1), 17-22, 2004.

Grassadonia A, Tinari N, Fiorentino B, Suzuki K, Nakazato M, De Tursi M, Giuliani C, Napolitano G, Singer DS, Iacobelli S, Kohn LD: The 90K protein increases major histocompatibility complex class I expression and is regulated by hormones, gamma-interferon, and double-strand polynucleotides. Endocrinology 145(10), 4728-4736, 2004.

Takeshita F, Suzuki K, Sasaki S, Ishii N, Klinman DM, Ishii KJ: Transcriptional regulation of the human TLR9 gene. J Immunol 173(4), 2552-2561, 2004.

Yoshida A, Hisatome I, Taniguchi S, Sasaki N, Yamamoto Y, Miake J, Fukui H, Shimizu H, Okamura T, Okura T, Igawa O, Shigemasa C, Green ED, Kohn LD, Suzuki K: Mechanism of iodide/chloride exchange by pendrin. Endocrinology 145(9), 4301-4308, 2004.


Kondo T, Nakamura N, Suzuki K, Murata S, Muramatsu A, Kawaoi A, Katoh R: Expression of human pendrin in diseased thyroids. J Histochem Cytochem 51(2), 167-173, 2003.

Toda S, Aoki S, Suzuki K, Koike E, Ootani A, Watanabe K, Koike N, Sugihara H: Thyrocytes, but not C cells, actively undergo growth and folliculogenesis at the periphery of thyroid tissue fragments in three-dimensional collagen gel culture. Cell Tissue Res 312(3), 281-289, 2003.

鈴木 幸一: ペンドレッド症候群とPDS遺伝子異常症. 内分泌・糖尿病科 17(4), 410-416, 2003.

鈴木 幸一: 【分子甲状腺学の進歩2003】 甲状腺濾胞形成機構研究の新しい展開. ホルモンと臨床 51(2), 85-92, 2003.

鈴木 幸一: サイログロブリンによる甲状腺濾胞機能のネガティブフィードバック調節機構. 内分泌・糖尿病科 16(2), 172-183, 2003.


Suzuki K, Yanagi M, Mori-Aoki A, Moriyama E, Ishii KJ, Kohn LD: Transfection of single-stranded hepatitis A virus RNA activates MHC class I pathway. Clin Exp Immunol 127(2), 234-242, 2002.

Suzuki K, Royaux IE, Everett LA, Mori-Aoki A, Suzuki S, Nakamura K, Sakai T, Katoh R, Toda S, Green ED, Kohn LD: Expression of PDS/Pds, the Pendred syndrome gene, in endometrium. J Clin Endocrinol Metab 87(2), 938, 2002.

Rotman-Pikielny P, Hirschberg K, Maruvada P, Suzuki K, Royaux IE, Green ED, Kohn LD, Lippincott-Schwartz J, Yen PM: Retention of pendrin in the endoplasmic reticulum is a major mechanism for Pendred syndrome. Hum Mol Genet 11(21), 2625-2633, 2002.

Toda S, Watanabe K, Yokoi F, Matsumura S, Suzuki K, Ootani A, Aoki S, Koike N, Sugihara H: A new organotypic culture of thyroid tissue maintains three-dimensional follicles with C cells for a long term. Biochem Biophys Res Commun 294(4), 906-911, 2002.

Yoshida A, Taniguchi S, Hisatome I, Royaux IE, Green ED, Kohn LD, Suzuki K: Pendrin is an iodide-specific apical porter responsible for iodide efflux from thyroid cells. J Clin Endocrinol Metab 87(7), 3356-3361, 2002.

Hashimoto K, Maeda Y, Kimura H, Suzuki K, Masuda A, Matsuoka M, Makino M: Mycobacterium leprae infection in monocyte-derived dendritic cells and its influence on antigen-presenting function. Infect Immun 70(9), 5167-5176, 2002.

与儀 ヤス子,遠藤 真澄,坂場 智子,小林 政徳,加藤 秀樹,鈴木 幸一,野間口 博子: コンジェニック高血圧ヌードラットのらい菌感受性とサイトカイン産生能. 日本ハンセン病学会雑誌 71(1), 39-45, 2002.

Cheng X, Suzuki K, Wang L, Zhang J: The expression of pendred syndrome gene and the function of pendrin. Chinese J Endocrinol Metab 18(6), 495-497, 2002.

鈴木 幸一: 【分子甲状腺学の進歩2002】 ペンドレッド症候群原因遺伝子PDSの発現分布と機能. ホルモンと臨床 50(2), 169-174, 2002.


Royaux IE, Wall SM, Karniski LP, Everett LA, Suzuki K, Knepper MA, Green ED: Pendrin, encoded by the Pendred syndrome gene, resides in the apical region of renal intercalated cells and mediates bicarbonate secretion. Proc Natl Acad Sci U S A 98(7), 4221-4226, 2001.

Ishii KJ, Suzuki K, Coban C, Takeshita F, Itoh Y, Matoba H, Kohn LD, Klinman DM: Genomic DNA released by dying cells induces the maturation of APCs. J Immunol 167(5), 2602-2607, 2001.

Miyagi E, Katoh R, Li X, Lu S, Suzuki K, Maeda S, Shibuya M, Kawaoi A: Thyroid stimulating hormone downregulates vascular endothelial growth factor expression in FRTL-5 cells. Thyroid 11(6), 539-543, 2001.

Saito J, Kohn AD, Roth RA, Noguchi Y, Tatsumo I, Hirai A, Suzuki K, Kohn LD, Saji M, Ringel MD: Regulation of FRTL-5 thyroid cell growth by phosphatidylinositol (OH) 3 kinase-dependent Akt-mediated signaling. Thyroid 11(4), 339-351, 2001.

Sellitti DF, Suzuki K, Doi SQ, Lagranha C, Machado M, Matos T, Kohn LD: Thyroglobulin increases cell proliferation and suppresses Pax-8 in mesangial cells. Biochem Biophys Res Commun 285(3), 795-799, 2001.

Kohn LD, Suzuki K, Nakazato M, Royaux I, Green ED: Effects of thyroglobulin and pendrin on iodide flux through the thyrocyte. Trends Endocrinol Metab 12(1), 10-16, 2001.


Caturegli P, Hejazi M, Suzuki K, Dohan O, Carrasco N, Kohn LD, Rose NR: Hypothyroidism in transgenic mice expressing IFN-gamma in the thyroid. Proc Natl Acad Sci U S A 97(4), 1719-1724, 2000.

Katoh R, Kawaoi A, Miyagi E, Li X, Suzuki K, Nakamura Y, Kakudo K: Thyroid transcription factor-1 in normal, hyperplastic, and neoplastic follicular thyroid cells examined by immunohistochemistry and nonradioactive in situ hybridization. Mod Pathol 13(5), 570-576, 2000.

Katoh R, Miyagi E, Nakamura N, Li X, Suzuki K, Kakudo K, Kobayashi M, Kawaoi A: Expression of thyroid transcription factor-1 (TTF-1) in human C cells and medullary thyroid carcinomas. Hum Pathol 31(3), 386-393, 2000.

Medina DL, Suzuki K, Pietrarelli M, Okajima F, Kohn LD, Santisteban P: Role of insulin and serum on thyrotropin regulation of thyroid transcription factor-1 and pax-8 genes expression in FRTL-5 thyroid cells. Thyroid 10(4), 295-303, 2000.

Mori-Aoki A, Pietrarelli M, Nakazato M, Caturegli P, Kohn LD, Suzuki K: Class II transactivator suppresses transcription of thyroid-specific genes. Biochem Biophys Res Commun 278(1), 58-62, 2000.

Nakazato M, Chung HK, Ulianich L, Grassadonia A, Suzuki K, Kohn LD: Thyroglobulin Repression of Thyroid Transcription Factor 1 (TTF-1) Gene Expression Is Mediated by Decreased DNA Binding of Nuclear Factor I Proteins Which Control Constitutive TTF-1 Expression. Mol Cell Biol 20(22), 8499-8512, 2000.

Ringel MD, Greenberg M, Chen X, Hayre N, Suzuki K, Priebat D, Saji M, Burman KD: Cytotoxic activity of 2',2'-difluorodeoxycytidine (gemcitabine) in poorly differentiated thyroid carcinoma cells. Thyroid 10(10), 865-869, 2000.

Royaux IE, Suzuki K, Mori A, Katoh R, Everett LA, Kohn LD, Green ED: Pendrin, the protein encoded by the Pendred syndrome gene (PDS), is an apical porter of iodide in the thyroid and is regulated by thyroglobulin in FRTL-5 cells. Endocrinology 141(2), 839-845, 2000.

Schuppert F, Ehrenthal D, Frilling A, Suzuki K, Napolitano G, Kohn LD: Increased major histocompatibility complex (MHC) expression in nontoxic goiters is associated with iodide depletion, enhanced ability of the follicular thyroglobulin to increase MHC gene expression, and thyroid autoantibodies. J Clin Endocrinol Metab 85(2), 858-867, 2000.

Kohn LD, Napolitano G, Singer DS, Molteni M, Scorza R, Shimojo N, Kohno Y, Mozes E, Nakazato M, Ulianich L, Chung HK, Matoba H, Saunier B, Suzuki K, Schuppert F, Saji M: Graves' disease: a host defense mechanism gone awry. Int Rev Immunol 19(6), 633-664, 2000.

Kohn LD, Shimojo N, Kohno Y, Suzuki K: An animal model of Graves' disease: understanding the cause of autoimmune hyperthyroidism. Rev Endocr Metab Disord 1(1-2), 59-67, 2000.

Suzuki K, Nakazato M, Ulianich L, Mori-Aoki A, Moriyama E, Chung HK, Pietrarelli M, Grassadonia A, Matoba H, Kohn LD: Thyroglobulin autoregulation of thyroid-specific gene expression and follicular function. Rev Endocr Metab Disord 1(3), 217-224, 2000.


Suzuki K, Mori A, Ishii KJ, Saito J, Singer DS, Klinman DM, Krause PR, Kohn LD: Activation of target-tissue immune-recognition molecules by double-stranded polynucleotides. Proc Natl Acad Sci U S A 96(5), 2285-2290, 1999.

Suzuki K, Mori A, Lavaroni S, Miyagi E, Ulianich L, Katoh R, Kawaoi A, Kohn LD: In vivo expression of thyroid transcription factor-1 RNA and its relation to thyroid function and follicular heterogeneity: identification of follicular thyroglobulin as a feedback suppressor of thyroid transcription factor-1 RNA levels and thyroglobulin synthesis. Thyroid 9(4), 319-331, 1999.

Suzuki K, Mori A, Saito J, Moriyama E, Ullianich L, Kohn LD: Follicular thyroglobulin suppresses iodide uptake by suppressing expression of the sodium/iodide symporter gene. Endocrinology 140(11), 5422-5430, 1999.

Ulianich L, Suzuki K, Mori A, Nakazato M, Pietrarelli M, Goldsmith P, Pacifico F, Consiglio E, Formisano S, Kohn LD: Follicular thyroglobulin (TG) suppression of thyroid-restricted genes involves the apical membrane asialoglycoprotein receptor and TG phosphorylation. J Biol Chem 274(35), 25099-25107, 1999.

Suzuki K, Lavaroni S, Mori A, Yamamoto K, Yi X, Miyagi E, Katoh R, Kohn LD, Kawaoi A: Thyroglobulin: a master regulator of follicular function via transcriptional suppression of thyroid specific genes. Acta Histochem Cytochem 32(2), 111-119, 1999.

Suzuki K, Mori A, Lavaroni S, Ulianich L, Miyagi E, Saito J, Nakazato M, Pietrarelli M, Shafran N, Grassadonia A, Kim WB, Consiglio E, Formisano S, Kohn LD: Thyroglobulin regulates follicular function and heterogeneity by suppressing thyroid-specific gene expression. Biochimie 81(4), 329-340, 1999.

鈴木 幸一: 甲状腺細胞の自己免疫発症機序. 内分泌・糖尿病科 9(4), 385-392, 1999.

Kohn LD, Suzuki K, Mori A, Ishii JK, Klinman DM. Immune activation of double strand polynucleotides. Canadian Patent Application No. 2,309,762, filed September 10, 1999.

Kohn LD, Suzuki K, Mori A, Ishii JK, Klinman DM. Immune activation of double strand polynucleotides. European Patent Application No. 99969109.0, filed September 10, 1999.


Suzuki K, Lavaroni S, Mori A, Ohta M, Saito J, Pietrarelli M, Singer DS, Kimura S, Katoh R, Kawaoi A, Kohn LD: Autoregulation of thyroid-specific gene transcription by thyroglobulin. Proc Natl Acad Sci U S A 95(14), 8251-8256, 1998.

Suzuki K, Lavaroni S, Mori A, Okajima F, Kimura S, Katoh R, Kawaoi A, Kohn LD: Thyroid transcription factor 1 is calcium modulated and coordinately regulates genes involved in calcium homeostasis in C cells. Mol Cell Biol 18(12), 7410-7422, 1998.

Suzuki K, Kobayashi Y, Katoh R, Kohn LD, Kawaoi A: Identification of thyroid transcription factor-1 in C cells and parathyroid cells. Endocrinology 139(6), 3014-3017, 1998.

Taniguchi SI, Shong M, Giuliani C, Napolitano G, Saji M, Montani V, Suzuki K, Singer DS, Kohn LD: Iodide suppression of major histocompatibility class I gene expression in thyroid cells involves enhancer A and the transcription factor NF- kappa B. Mol Endocrinol 12(1), 19-33, 1998.

Montani V, Shong M, Taniguchi SI, Suzuki K, Giuliani C, Napolitano G, Saito J, Saji M, Fiorentino B, Reimold AM, Singer DS, Kohn LD: Regulation of major histocompatibility class II gene expression in FRTL- 5 thyrocytes: opposite effects of interferon and methimazole. Endocrinology 139(1), 290-302, 1998.

Montani V, Taniguchi SI, Shong M, Suzuki K, Ohmori M, Giuliani C, Napolitano G, Saji M, Fiorentino B, Reimold AM, Ting JP, Kohn LD, Singer DS: Major histocompatibility class II HLA-DR alpha gene expression in thyrocytes: counter regulation by the class II transactivator and the thyroid Y box protein. Endocrinology 139(1), 280-289, 1998.

Balducci-Silano PL, Suzuki K, Ohta M, Saito J, Ohmori M, Montani V, Napolitano G, Shong M, Taniguchi SI, Pietrarelli M, Lavaroni S, Mori A, Singer DS, Kohn LD: Regulation of major histocompatibility (MHC) class II human leukocyte antigen-DR alpha gene expression in thyrocytes by single strand binding protein-1, a transcription factor that also regulates thyrotropin receptor and MHC class I gene expression. Endocrinology 139(5), 2300-2313, 1998.

Katoh R, Suzuki K, Miyagi E, Kawaoi A: Thyroid Transcription Factor (TTF-1). Acta Histochem Cytochem 31(4), 287-290, 1998.


Saji M, Shong M, Napolitano G, Palmer LA, Taniguchi SI, Ohmori M, Ohta M, Suzuki K, Kirshner SL, Giuliani C, Singer DS, Kohn LD: Regulation of major histocompatibility complex class I gene expression in thyroid cells. Role of the cAMP response element-like sequence. J Biol Chem 272(32), 20096-20107, 1997.

Kohn LD, Suzuki K, Hoffman WH, Tombaccini D, Marcocci C, Shimojo N, Watanabe Y, Amino N, Cho BY, Kohno Y, Hirai A, Tahara K: Characterization of monoclonal thyroid-stimulating and thyrotropin binding-inhibiting autoantibodies from a Hashimoto's patient whose children had intrauterine and neonatal thyroid disease. J Clin Endocrinol Metab 82(12), 3998-4009, 1997.

Yang Y, Fujii H, Matsumoto Y, Suzuki K, Kawaoi A, Suda K: Carcinoma of the gallbladder and anomalous arrangement of the pancreaticobiliary ductal system: cell kinetic studies of gallbladder epithelial cells. J Gastroenterol 32(6), 801-807, 1997.

加藤 良平, 宮城 恵理, 鈴木 幸一, 川生 明: 甲状腺転写因子TTF-1. 病理と臨床 15, 145-155, 1997.

Ohmori M, Ohta M, Shimura H, Shimurat Y, Suzuki K, Kohn LD: Cloning of the single strand DNA-binding protein important for maximal expression and thyrotropin (TSH)-induced negative regulation of the TSH receptor. Mol Endocrinol 10(11), 1407-1424, 1996.

Suzuki K, Hemmi A, Katoh R, Kawaoi A: Differential image analysis of proliferating cell nuclear antigen (PCNA) expression level during experimental thyroid carcinogenesis. Acta Histochem Cytochem 29(2), 99-103, 1996.

鈴木 幸一, 加藤 良平, 川生 明: ホルモン産生・機能分化の制御因子 TTF-1(甲状腺特異的転写因子). 医学のあゆみ 179(12〜13), 909-912, 1996.

Hemmi A, Komiyama A, Ohno S, Fujii Y, Kawaoi A, Katoh R, Suzuki K: Different organization of intermediate filaments in columnar cells of rat large intestinal mucosa as revealed by confocal laser scanning microscopy and quick-freezing and deep-etching method. Virchows Arch 426(4), 401-410, 1995.

Katoh R, Bray CE, Suzuki K, Komiyama A, Hemmi A, Kawaoi A, Oyama T, Sugai T, Sasou S: Growth activity in hyperplastic and neoplastic human thyroid determined by an immunohistochemical staining procedure using monoclonal antibody MIB-1. Hum Pathol 26(2), 139-146, 1995.

Kohn LD, Giuliani C, Montani V, Napolitano G, Ohmori M, Ohta M, Saji M, Schuppert F, Shong M, Suzuki K, Taniguchi S-I, Yano K and Singer DS. Antireceptor Immunity. In: Rayner D, Cooke A and Champion B (Eds): Thyroid Immunity. RG Landes Biomedical Publishers, Austin/Georgetown, Texas, 115-170. 1995.

川生 明,鈴木 幸一.甲状腺内分泌の形態学的特徴.笹野信昭 編,臨床内分泌病理診断学.医歯薬出版,東京,114-119 1994.

Katoh R, Kawaoi A, Muramatsu A, Hemmi A, Suzuki K: Birefringent (calcium oxalate) crystals in thyroid diseases. A clinicopathological study with possible implications for differential diagnosis. Am J Surg Pathol 17(7), 698-705, 1993.

Katoh R, Muramatsu A, Kawaoi A, Komiyama A, Suzuki K, Hemmi A, Katayama S: Alteration of the basement membrane in human thyroid diseases: an immunohistochemical study of type IV collagen, laminin and heparan sulphate proteoglycan. Virchows Arch A Pathol Anat Histopathol 423(6), 417-424, 1993.

Katoh R, Suzuki K, Hemmi A, Kawaoi A: Nature and significance of calcium oxalate crystals in normal human thyroid gland. A clinicopathological and immunohistochemical study. Virchows Arch A Pathol Anat Histopathol 422(4), 301-306, 1993.

中沢 勉, 岸保 鉄, 久松 健一, 荻野 純、鈴木 幸一、加藤 良平、村上 嘉彦: 耳下腺原発癌肉腫の一症例. 頭頸部腫瘍 19(2), 269-272, 1993.
鈴木 幸一, 川生 明: 病理組織と免疫 組織中細胞表面マーカーの検出法 免疫蛍光法. Medical Technology 21(7), 690-692, 1993.

Katoh R, Iida Y, Suzuki K, Kawaoi A, Muramatsu A: Immunohistochemical and immunoelectron microscopical localization of procollagen III peptide in papillary carcinoma of thyroid. Endocr Pathol 3, 129-133, 1992.

Katoh R, Sasaki J, Kurihara H, Suzuki K, Iida Y, Kawaoi A: Multiple thyroid involvement (intraglandular metastasis) in papillary thyroid carcinoma. A clinicopathologic study of 105 consecutive patients. Cancer 70(6), 1585-1590, 1992.

Munim A, Asayama K, Dobashi K, Suzuki K, Kawaoi A, Kato K: Immunohistochemical localization of superoxide dismutases in fetal and neonatal rat tissues. J Histochem Cytochem 40(11), 1705-1713, 1992.

Sasaki A, Naganuma H, Kimura R, Isoe S, Nakano S, Nukui H, Suzuki K, Kawaoi A: Proliferating cell nuclear antigen (PCNA) immunostaining as an alternative to bromodeoxyuridine (BrdU) immunostaining for brain tumours in paraffin embedded sections. Acta Neurochir (Wien) 117(3-4), 178-181, 1992.

Suzuki K, Kobayashi M, Kawaoi A: Immunohistochemical demonstration of proliferating cell nuclear antigen in growing cells on formalin-fixed, paraffin-embedded tissue sections. Acta Histochem Cytochem 25(1&2), 13-18, 1992.

Dobashi K, Munim A, Asayama K, Suzuki K, Kato K, Kawaoi A: Immunohistochemical study on two intracellular superoxide dismutases in fetal rat. Acta Histochem Cytochem 24(5), 511-516, 1991.

Katoh R, Iida Y, Suzuki K, Kawaoi A: Immunohistochemical localization of procollagen III peptide in thyroid diseases. Acta Histochem Cytochem 24(5), 519-524, 1991.

Kawaoi A, Matsumoto H, Suzuki K, Moriyama S: Histogenesis of diisopropanolnitrosamine (DIPN)-induced tumors of the rat thyroid gland. Virchows Arch B Cell Pathol Incl Mol Pathol 61(1), 49-56, 1991.

Kawaoi A, Suzuki K, Katoh R: Application of proliferating cell nuclear antigen (PCNA) immunostaining to diagnostic histopathology. Acta Anatomica Sinica 22(2), 240-241, 1991.

Matsumoto H, Kato Y, Suzuki K, Kawaoi A: Androgen dependent tumorigenesis in rat thyroid gland induced by diisopropanolnitrosamine (DIPN) administration. Yamanashi Med J 6(5), 55-61, 1991.

Suzuki K, Matsumoto H, Kobayashi M, Kawaoi A, Asayama K, Moriyama S: Immunohistochemical localization of copper-zinc and manganese superoxide dismutases in diisopropanolnitrosamine-induced rat thyroid lesions. Acta Histochem Cytochem 24(1), 69-73, 1991.

鈴木 幸一, 加藤 良平, 川生 明: 抗PCNAモノクローナル抗体による増殖期細胞の同定 ホルマリン固定パラフィン包埋切片を用いた免疫組織化学的検討. 医学のあゆみ 157(11), 655-656, 1991.

鈴木 幸一, 川生 明: 酵素抗体法. Medical Technology 19(2), 129-134, 1991.

Munim A, Asayama K, Uchida N, Dobashi K, Hayashibe H, Kobayashi M, Suzuki K, Kawaoi A, Kato K: Immunohistochemical localization of copper-zinc and manganese superoxide dismutases in human tissues. Yamanashi Med J 5(4), 181-186, 1990.

鈴木 幸一, 大戸 斉, 遠山 博: 埼玉県における輸血後肝炎の発症状況. 血液事業 11(2), 259-263, 1988.

日野 邦彦,鈴木 幸一,下田 和美,安田 清美,近藤 俊郎,丹羽 寛: 〔B型肝炎 予防と治療の最新情報〕B型慢性肝炎の治療 ステロイド離脱療法の基礎と問題点. Medical Practice 5(4), 619-627, 1988.

Kimura Y, Toki H, Okabe K, Suzuki K, Hayakawa T: Establishment and characterization of a monocytic cell line which express the Interleukin-2 receptor. Jpn J Cancer Res 77(9), 862-867, 1986.

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