Manabe Lab.

Department of Systems Medicine, Chiba University

We are interested in molecular mechanisms of cardiovascular, metabolic and kidney diseases and translation of the basic science into novel therapeutic strategies. Our current projects focus on immunometabolic mechanisms in chronic inflammatory diseases and maintenance of homeostasis via the multi-system interaction. We are analyzing the crosstalk between metabolism and immunity at the cell, tissue and system levels. We are particularly interested in divergent functions and phenotypes of macrophages in physiology and pathobiology. We use a variety of technologies, including NGS, single-cell analysis, FACS, and in vivo imaging.

PostDoc and Graduate Student positions are available. JREC-IN

Contact: imanabe@chiba-u.jp

Interests

Non-communicable disease

Organ crosstalk/Organ system network

Epigenetics/Single cell analysis

Macrophage

Immunometabolism

Inflammaging