The 81th Annual Meeting of
The Japanese Pharmacological Society
March 17-19, 2008
Yokohama, Japan
Chairman: Norio Matsuki
Abstracts
Secretariat: Yuji Ikegaya
Grad School of Pharmaceutical Sciences, The University of Tokyo
Special Lectures
SL1
S-nitrosylation of proteins updated
Jonathan S. Stamler .......... 2P
SL2
Predicting nausea and vomiting in humans: Understanding the translation of
animal models to man
Paul Andrews .......... 2P
SL3
Development and maintenance of neuronal polarity
Mu-ming Poo .......... 2P
SL4
Inverse agonists prevent cardiac hypertrophy
Issei Komuro .......... 2P
SL5
Amygdala and pain - Pharmacological mechanisms and targets
Volker Neugebauer .......... 3P
SL6
From orphan GPCR to behaviors
Masashi Yanagisawa .......... 3P
SL7
From glutamate receptors to brain dynamics
Masayoshi Mishina.......... 3P
SL8
"UDP glucuronosyltransferases (UGT), the kidney, and NSAID nephrotoxicity"
Kathleen Knights .......... 3P
Educational Lectures
EL-1
From discovery of endothelin to clinical application of its receptor antagonists
Katsutoshi Goto ............ 6P
EL2
Your dream finally come true
Toshitaka Nabeshima ............ 6P
Ebashi Setsuo Award Lecture
EAL
Endothelin and endothelial dysfunction
Tomoh Masaki ........... 8P
Award Lectures
AL1
Mechanisms of cutaneous itch: New itch mediators and enhancement factors
produced by keratinocytes
Tsugunobu Andoh ............ 10P
AL2
Roles of snapin in a1A-adrenoceptor-induced calcium
Fumiko Suzuki ............. 10P
Symposia
S1A1
Free radical/oxidative stress-mediated physiological responses
Takashi Uehara and Hitoshi Kurose ............. 12P
S1B1
Neuronal death and neuroprotective mechanisms in stress-induced
neurodegenerative diseases
Hiroshi Ueda and Yasuyoshi Watanabe ..............................................
13P
S1C1
Extracellular nucleotides in action: Molecular dynamics and pathophysiological
implications in the brain function
Kazuhide Inoue and Fusao Kato .............
14P
S1D1
Pharmacology of Kampo medicine: Basic evidences to clinical applications
Hiroyasu Sato and Takuya Kawakita ............. 15P
S1A2
Toxicology and drug safety - Joint symposium of the Japanese Society of
Toxicology and the Japanese Pharmacological Society
Taku Nagao and Akinori Akaike .............
17P
S1B2
Studies on gastrointestinal pathophysiology using transgenic animals
Kohji Takeuchi and Akinori Yanaka ............. 18P
S1C2
New pathophysiological findings related to histamine receptors
Hiroshi Ohtsu and Noriyasu Hirasawa .............
19P
S1D2
Drug development targeting GSK-3βmediated signal transduction pathway
Toshiyuki Sasaguri and Akihiko Wada .............
20P
S1A3
Pharmacological and clinical pharmacological approaches for molecular
imaging
Kazuo Umemura and Kazuhiko Yanai ............. 21P
S1B3
Basic and translational research on proteinase-activated receptors, seeking
out a new therapeutic target
Katsuya Hirano and Atsufumi Kawabata .............
22P
S1C3
Emotional aspect of pain - Approaches from basic and clinical sciences
Masabumi Minami and Takahiro Ushida .............
24P
S1D3
Pharmacological approach in health foods: From basic science research to
venture business
Nobuyuki Yanagihara and Toshihiko Ohsawa .............
25P
S2A1
Pharmacological evaluation of the risk of drug-induced long QT syndrome
Atsushi Sugiyama and Yuji Kumagai ............. 26P
S2B1
Frontiers of antibody therapeutics and their potential
Masahiro Nishibori and Shuji Mori ............. 27P
S2C1
Toward drug discovery for overcoming CKD
Toshiaki Tamaki and Yasuo Matsumura .............
28P
S2D1
Pathophysiological study and target validation of lower digestive tract disorder
Masatoshi Hori and Shinichi Kato .............
30P
S2B2
New aspects for the treatment of cardiac diseases: Based on the diversity of
functional controls on cardiac muscles
Takeshi Suzuki and Hikaru Tanaka .............
31P
S2C2
Basic and clinical knowledge for understanding the treatment of chronic cough
Junzo Kamei and Masaki Fujimura .............
33P
S2D2
Recent achievements available for the treatment of vascular diseases
Kazuhiro Kohama and Sei Kobayashi .............
34P
S2C3
Novel drug targets for the treatment of bone diseases
Keiichi Ohya and Shoji Yamada ............. 35P
S2D3
New topics in vasopressin receptors and approach to novel drugs
Yukio Takano and Gozo Tsujimoto .............
37P
S3A1
Novel approaches for understanding of pathophysiology and drug development
using transgenic mice of mental disorders
Kohji Fukunaga and Hideaki Hara .............
38P
S3B1
Molecular targeted drugs for cancer treatment
Hsashi Yamada and Naoki Agata ............. 39P
S3C1
Analysis of the mechanism for the development of allergic skin inflammation
and the application for its treatment
Kazuo Ohuchi and Tadashi Terui ............. 40P
S3D1
Space Pharmacology: Update findings and perspectives
Mitsuhiro Yoshioka and Hisashi Ohta .............
42P
S3A2
Paradigm shift of drug discovery -Drug discovery research by new tools-
Toichi Takenaka and Hideaki Hara .............
43P
S3B2
Reliable scientific evidence for palliative care medicine: The new approach
to
advanced 'Pain Research'
Minoru Narita and Yasuhito Uezono ............. 44P
S3C2
Signaling complex of ion channnels and transporters with regulator proteins
in
membrane microdomains as a novel class of drug targets
Yuji Imaizumi and Takahiro Iwamoto ............. 45P
S3D2
Hydrogen sulfide and carbon monoxide as physiological mediators
Hideo Kimura and Ichiro Niki ............. 47P
Excellent Mini Simposia .............
49P
Free Communications
Oral Sessions. ......... 75P
Poster Sessions .......... 123P
Author Index ............. 1
Subject Index ............. 35
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