The 79th Annual Meeting of
The Japanese Pharmacological Society
March 8-10, 2006
Yokohama, Japan
Chairman: Masayoshi Mishina
Abstracts
Secretariat: Tomoyuki Yoshida
Department of Molecular Neurobiology and Pharmacology
Graduate School of Medicine, University of Tokyo
Tokyo 113-0033, Japan
Plenary Lectures
PL-1
From genes to drugs for memory
Tim Tully .......... 2P
PL-2
Distinct signal transduction pathways of physiologic and pathologic cardiac
hypertrophy
Seigo Izumo .......... 2P
PL-3
Molecular basis of muscular dystrophy and therapeutic strategies
Kevin P. Campbell .......... 3P
PL-4
Glutamate receptors - dynamic structure and subunit-specific signaling
Morgan Sheng ......... 3P
PL-5
Prostanoid receptors; from cDNA cloning to translational research
Shuh Narumiya .......... 4P
Invited Lectures
IL-1
Pharmacogenomics of opioid drugs
Andrew Somogyi .......... 6P
IL-2
Metabolic syndrome - pathogenesis and treatment strategy
Takashi Kadowaki .......... 6P
IL-3
Self-renewal of neural stem cells and CNS-repair
Hideyuki Okano .......... 7P
Educational Lectures
EL-1
GABAB receptor - structure and function in alimentary tract
KohtaroTaniyama .......... 10P
EL-2
Pharmacological basis of traditional medicine as curative polypharmacy in the
21st century
Takeshi Miyata ......... 10P
EL-3
Do drugs suppress lethal arrhythmias?
Keitaro Hashimoto .......... 11P
Keynote Lecture
KL-1
In search of new chemotherapy for cancer using mouse models
Makoto Mark Taketo .......... 14P
KL-2
Schizophrenia and the mode of functions of the risk factors in neurons
Kozo Kaibuchi .......... 14P
Award Lectures
AL-1
Structural and physiological plasticity of hippocampal mossy fibers
Yuji Ikegaya ......... 16P
AL-2
Mitochondrial dysfunction and apoptosis in neurodegenerative diseases
Kazuhiro Takuma ......... 16P
AL-3
Visualization of intracellular Ca2+ signaling
Kenzo Hirose ......... 17P
Symposia
S1A1
Potential drug targets for schizophrenia
Masaya Tohyama and Akemichi Baba .......... 20P
S1B1
RNAi provides a new approach to drug discovery and development
Kenzo Hirose .......... 21P
S1C1
Analysis of transporters responsible for drug action and adverse effects
Hiroshi Suzuki and Yoshikatsu Kanai .......... 22P
S1D1
New development of nitric oxide research
Tomio Okamura and Toshiaki Tamaki .......... 23P
S1A2
Genome-based screening - new strategies and concepts -
Yutaka Suzuki and Hiroki Ueda ......... 24P
S1B2
New functions of purinergic receptors in CNS: Novel drug targets
Kazuhide Inoue and Masabumi Minami .......... 26P
S1C2
Influences of environmental chemical pollutants on brain neuronal functions
Tsutomu Suzuki and Nobuyuki Yanagihara .......... 27P
S1D2
Progress in allergy signal research of mast cell
Hiroyuki Fukui and Hiroshi Ohtsu .......... 28P
S1A3
New step of live imaging - from a molecule to whole body-
Naoaki Saito and Atsushi Miyawaki ......... 30P
S1B3
Novel animal models as research tools for functional psychiatric diseases
Naomi Eguchi and Junzo Kamei .......... 31P
S1C3
Pros and cons of in vitro study for evaluation of pharmacological effects
Yuji Yoshiyama and Masaichi-Chang-il Lee .......... 32P
S1D3
Regulation of immune response by autacoids and neurotransmitters
Masahiro Nishibori and Koichiro Kawashima .......... 34P
S2A1
Biosimulation in drug-development
Yoshihisa Kurachi and Haruki Nakamura .......... 35P
S2B1
Gender difference and drugs
Mitsuru Kawaguchi and Tsutomu Suzuki .......... 36P
S2C1
New models for functional analysis in life sciences
Hirofumi Kai and Masayuki Miura .......... 37P
S2D1
Involvement of CaM-kinase family in brain disease and medicine development
Hideyuki Yamamoto and Yasuharu Sasaki .......... 38P
S2B2
Animal experiments recommended by Japanese Pharmacological Society (Evaluation
and decrease of pain)
Yasuo Ohno and Hajime Yasuhara .......... 40P
S2C2
Chemical biology and drug discovery
Masatoshi Hagiwara and Hiroyuki Kagechika .......... 41P
S2D2
Molecular mechanism and novel therapeutic strategies of vascular diseases
Kazuhiro Kohama and Shokei Mitsuyama .......... 43P
S2C3
G protein-coupled receptors & signal molecules as drug targets
Hitoshi Kurose and Gozoh Tsujimoto .......... 44P
S2D3
Frontier of research in gastrointestinal diseases
Hiroshi Ozaki and Koji Takeuchi .......... 45P
S2E1
From molecule to brain: integrative approaches toward dynamics of neural circuit
assembly and neural functions
Yoshio Goshima and Shigeo Okabe .......... 47P
S3A1
Strategies for treatment of life style-related diseases
Koichi Nakayama and Atsushi Nakajima .......... 48P
S3B1
Intractable progressive neural diseases; Recent studies and therapeutic strategies
Takeshi Suzuki and Takaomi C. Saido .......... 49P
S3C1
Novel roles and drug targets of physiologically active peptides
Haruhiro Higashida and Masataka Majima ......... 51P
S3D1
Various function of circadian clock genes - from diseases to clinical drugs
-
Shigenobu Shibata and Shigehiro Ohdo .......... 52P
S3A2
Pharmacogenomics for pharmacokinetics, pharmacodynamics and toxicodynamics;
Comparative pharmacogenomic analysis of the inter-individual variability and
species differences
Yuichi Sugiyama and Junichi Azuma .......... 53P
S3B2
Basic and clinical research of neuroprotection - Approaches from glutamate,
endoplasmic reticulum (ER) stress, and amyloid beta
Yasushi Ohizumi and Hideaki Hara .......... 55P
S3C2
Device function of salivary glands utilized for systemic diagnosis and therapy
Yasuko Ishikawa and Mitsuru Kawaguchi .......... 56P
S3D2
Recent advances of non-invasive molecular imaging
Kazuhiko Yanai and Tetsuya Suhara .......... 58P
Free Communications
Oral Sessions .......... 60P
Poster Sessions .......... 136P
Author Index
Subject Index
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