J. Pharmacol. Sci. 91 Supplement I (2003)

The 76th Annual Meeting

 

March 24-26, 2003
Fukuoka

Chairman: Yushi Ito

Abstracts


Secretariat
Ryuji Inoue
Department Pharmacology, Graduate School of Medical Sciences, Kyushu University
Fukuoka 812-8582
Phone: +81-92-642-6076 Fax: +81-92-642-6079
E-mail: inouery@pharmaco.med.kyushu-u.ac.jp


Contents

Preliminaryl Lectures
PL-1
Calcium entry channels.
David Clapham .......... 2P

PL-2
Involvement of interstitial cells of Cajal in 'myogenic' and neuronal control of gastric motility.
David Hirst .......... 2P

PL-4
The neurobiology of synaptic transmission.
Paul Greengard .......... 2P

PL-6
Single molecule nano-bioscience.
Toshio Yanagida.......... 2P

PL-8
Search for drug targets based on genomic technologies.
Yasuhiko Masuho.......... 3P

Educational Lectures
EL-1
Teaching pharmacology in 2010.
Ian Hughes.......... 6P

EL-2
Does co-release of GABA and Gly occur from a single CNS neuron?
Norio Akaike .......... 6P

EL-3
Isolation and pharmacological effects of serofendic acid, a novel neuroprotective substance derived from fetal calf serum.
Akinori Akaike.......... 6P

EL-4
High resolution studies of transmitter release mechanisms, at the level of the individual varicosity, in sympathetic nerve terminals.
Tom Cunnane.......... 6P

EL-5
Ca2+ sensitizers: characteristics, classification and potential clinical relevance.
Masao Endoh.......... 7P

Award Lectures
ALPA-1
Role of chymase in vascular diseases and the efficacy of chymase inhibitor.
Shinji Takai.......... 10P

ALPA-2
Molecular mechanisms controlling actin reorganization during neurite remodeling.
Haruhiko Bito.......... 10P

ALPA-3
Molecular pharmacology of opioid receptors.
MasabumiMinami.......... 10P

Symposia
S2
Recent functional approaches to the 'synapse'.
Norio Akaike and Sumiko Mochida.......... 12P

S3
Update and perspective of studies on proteasea and diseases.
Takaomi Saido and Kenji Yamamoto .......... 13P

S5
Toward "Decade of Pain Control and Research" -frontiers of pain research.
Megumu Yoshimura and Hiroshi Ueda.......... 14P

S6
Physiology and pharmacology of prostaglandin D2 and related molecules.
Yoshihiro Urade and Toshiyuki Sasaguri.......... 15P

S8
New therapeutic strategies for immune and allergic diseases revealed by transgenic animal studies.
Shu Narumiya and Kouji Matsushima......... 17P

S9
The forefront of drug discovery -application of cutting edge technology to the pharmacological evaluation-.......... 18P

S10
Biological clock research from molecular to physiological and pharmacological aspects.
Sigenobu Shibata and Sato Honma .......... 19P

S11
Molecular dynamisms modulating synaptic function.
Naomasa Miki and Takako Shosaku .......... 20P

S15
Forefront of Na+/Ca+ exchanger: physiological, pharmacological, and molecular biological studies.
Satoshi Matsuoka and Takahiro Iwamoto ....... 21P

S23
Pharmacological analysis of brain functions using positron emission tomography.
Kazuo Umemura and Seiji Yamamoto.......... 23P

S24
Molecular and functional diversity of ion channels: a new perspective from recent studies.
Nobukuni Ogata and Tsutomu Tanabe .......... 24P

S26
Molecular basis of heart failure and its treatments.
Teruhiko Toyooka and Mikio Nakazawa.......... 25P

S28
Molecular and functional diversity of ATP-sensitive K+ channels: The pathophysiological roles and potential drug targets.
Makoto Arita and Haruaki Nakaya.......... 27P

S29
Voltage-dependent Ca2+ channels : molecular basis of cardiovascular control and neural functions.
Satomi Akahane and Shuji Kaneko.......... 28P

S30
Biological clock as a new target for rational drug therapy.
Akio Fujimura and Kenichi Honma .......... 29P

S32
Ionic mechanisms underlying the regulation of cell proliferation, differentiation and death.
Yuji Imaizumi and Yasuo Mori.......... 30P

S34
Physiology and pharmacology in diabetic research and versatile anti-diabetic therapy.
Toshihiko Yada and Ichiro Niki.......... 32P

S36
Influences of endocrine disrupting chemicals on the brain functions: Statement from the physiological and pharmacological point of view in 2003.
Nobuyuki Yanagihara and Yasuo Sakuma .......... 34P

S37
Pathophysiological interactions among neuronal, endothelial and glial cells.
Kiyoshi Matsumura and Masafumi Minami.......... 35P

S38
The newly clarified phenomena in histamine-related physiology and pharmacology.
Hiroshi Ohtsu and Takeshi Watanabe .......... 37P

S41
Signal transduction study on neurotrophic factors and their applications to drug development.
Yasushi Ohizumi and Norio Matsuki.......... 38P

S42
Receptor and channel gene manipulation for the disease models.
Teruyuki Yanagisawa and Fumitaka Ushikubi .......... 39P

S43
Functional coupling and localization of the central command and peripheral control through neromodulation by the inhibitory and excitatory amino acids.
Mitsuru Kawaguchi and Ryuji Matsuo ..........40P

S44
Novel physiological role of feeding-regulated peptides.
Yoichi Ueta snd Takeshi Sakurai ..........42P

S45
Osteoclasts and novel treatment strategies for bone diseases.
Koji Okabe and Sakae Tanaka ..........43P

S46
Angiogenesis: from bench to bed.
Ryuichi Morishita and Masataka Majima ..........44P

S47
Recent advances in the study of AMPA receptors -subunit assembly, functional expression and disease-
Takeyuki Suzuki and Keisuke Tsuzuki ..........46P

S50
New methods to evaluate endothelial function.
Masao Yoshizumi and Toshiaki Tamaki ..........47P

S51
Prospect of pharmacotherapeutics for prion disease.
Yasufumi Kataoka and Masami Niwa ..........48P

S52
Pharmacology in undergraduate education-in relation to the so-called core curriculum.
Kohtaro Taniyama ..........49P

S53
Proof of mysterious efficacy of ginseng -basic and clinical trials-
Eiichi Tachikawa and Hisao Saijou ..........50P

S55
Regulation of psychomotor functions by dopamine: integration of various approaches.
Akinori Nishi and Masashi Sasa ..........51P

S58
Pharmacology/Physiology study by functional genomic technology.
Gozoh Tsujimoto and Yoh Takuwa ..........52P

S59
PACAP/VIP signaling system: a novel target for new drug.
Atsuro Miyata and Akemichi Baba ..........53P

S60
Functional significance of adenosine and ATP signaling in the nervous system.
Tomoyuki Nishizaki and Fusao Kato ..........55P

S61
Multiplicity and diversity of serotonin receptors and function in the CNS.
Takashi Akasu and Yasuyuki Nomura ..........56P

S63
Excitatory and inhibitory receptors in brain-structure, function and disorder.
Masato Hirata and Hiroyuki Sugiyama ..........58P

S64
Regulatory mechanism of motility of the gastrointestinal tract.
Hikaru Suzuki and Fumiaki Hata ..........59P

S69
Roles of PPARγ: from physiological function to drug development.
Yoshinori Kamisaki and Atsushi Nakajima ..........61P

S70
ATP transport system: update.
Takeshi Katsuragi and Yasunobu Okada ..........62P

S71
Discovery of molecular targeting anticancer agents that block cell growth signaling of tyrosine kinesis.
Yoshiro Maru and Motonori Yamaguchi ..........63P

S75
Molecular mechanisms of vascular smooth muscle contraction as studied by pharmacological and physiological approaches.
Sei Kobayashi and Kazuhiro Kohama ..........64P

S77
Regulation of endothelial functions by mechanical stress.
Masahiro Sokabe and Fumihiko Kajiya ..........65P

Free Communications
Oral Sessions

Pathophysiology/Clinical Pharmacology ..........1C0900-1C1418
Angiogenesis ..........1H0900
Cerebral Circulation ..........1H1000-1H1024
Signal Transduction ..........1I0948-1I1530
Kidney/Fluid Balance ..........1J0900-1I1024
NO-cGMP-EDHF ..........1D1342-1D1542
Vascular Responses/ Functions ..........1H1454-1H1530
Atherosclerosis/ Vascular Remodelling/Apoptosis ..........1J1330-1J1442
Circulation: Baroreflex ..........1C1554
Endocrine ..........1D1642
Blood Pressure ..........1H1542-1H1642
Bioactive Substances ..........1I1542-1I1630
Nerotransmission/Neurosecretion ..........2C1006-2C1618
CNS: Cell Death/Pathophysiology ..........2D0830-2D1042
K channel ..........2H0830-2H0854
L-type Ca channel ..........2H0942-2H1030
Heart; Pathophysiology/Therapy ..........2I0842-2I0930
Integrative Function of CNS ..........2J0830-2J0930
Motor Functions ..........2C1730
CNS: Differentiation/Reproduction ..........2D1430
Autonomic Neuron/Sensory Neuron ..........2D1606-2D1718
Cation Channels ..........2H1454-2H1518
IP3/TRP Channels ..........2H1530-2H1642
Ca Release/Na-Ca Exchanger ..........2H1654-2H1718
Respiration ..........2I1430-2I1518
Heart: Arrhythmia ..........2I1642-2I1730
Taste/Olfactory Transduction ..........2K1706
Behaviour/Biorhythm ..........3D0830-3D0954
Smooth Muscle/Skeletal Muscle ..........3H0842-3H1606
Digestion/Absorption ..........3H0930-3H1018
Receptor ..........3I0830-3I0906
Heart: Remodelling ..........3I0942-3I1042
Pain ..........3C1430-3C1606
Immune Response/Inflammation/Allergy ..........3D1418-3D1618
Anion Channels ..........3I1442-3I1518

Poster Sessions
Bioactive Substances .......... 1P008-1P037
Signal Transduction .......... 1P060-1P111
Heart/Circulation .......... 1P122-1P289
Bone/Dental Pharmacology .......... 1P291-1P310
Pathophysiology/Clinical Pharmacology .......... 1P325-1P341
Endocrine .......... 1P358-1P364
Reproduction .......... 1P373
Nutrition/Metabolism/Body Temperature .......... 1P411-1P415
Autonomic Neuron/Sensory Neuron .......... 2P032-2P045
Neuron/Synapse .......... 2P105-2P136
Sensation .......... 2P156-2P205
Motor Functions .......... 2P230
Integrative Function .......... 2P258-2P291
Behaviour/Biorhythm .......... 2P320-2P347
Neurochemistry .......... 2P365-2P409
Neuropathophysiology .......... 2P417-2P421
CNS (Molecular Physiology; Ion Channels; Receptor; Growth/Differentiation/Ageing) .......... 2P425-2P454
Receptor/Channel/Transporter .......... 3P022-3P190
Respiration .......... 3P201-3P222
Kidney .......... 3P224-3P237
Blood ..........3P244-3P245
GI tract .......... 3P249-3P264
Smooth Muscle/Skeletal Muscle ..........3P265-3P329
Biochemical Pharmacology .......... 3P332-3P360
Immune Response/Inflammation .......... 3P363-3P395
Chemotherapy/Toxicology/Clinical Pharmacology/Others .......... 3P404-3P416

Author Index
Subject Index


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