The JPS Prize

The JPS Prize 2011 Awards

• Mechanism Underlying the Protective Effect of Tempol and Nω-Nitro-L-arginine Methyl Ester on Acoustic Injury: Possible Involvement of c-Jun N-Terminal Kinase Pathway and Connexin26 in the Cochlear Spiral Ligament
  Reiko Nagashima, Taro Yamaguchi, Hajime Tanaka, and Kiyokazu Ogita
  J Pharmacol Sci. 2010 ; 114 : 50-62
• Computational Analysis of the Effects of Antineoplastic Agents on Axonal Transport
  Yoshio Goshima, Hiroshi Usui, Takahito Shiozawa, Tomonobu Hida, Satoshi Kuraoka, Sayumi Takeshita, Naoya Yamashita, Yasushi Ichikawa, Yoshinori Kamiya, Takahisa Gotoh, and Toshiyuki Gotoh
  J Pharmacol Sci. 2010 ; 114 : 168-179
• Antipsychotic Potential of Quinazoline ErbB1 Inhibitors in a Schizophrenia Model Established With Neonatal Hippocampal Lesioning
  Makoto Mizuno, Yuriko Iwakura, Masako Shibuya, Yingjun Zheng, Takeyoshi Eda, Taisuke Kato, Yohei Takasu, and Hiroyuki Nawa
  J Pharmacol Sci. 2010 ; 114 : 320-331

The JPS Prize 2010 Awards

• Involvement of Tryptase and Proteinase-Activated Receptor-2 in Spontaneous Itch-Associated Response in Mice With Atopy-like Dermatitis
  Kenichiro Tsujii, Tsugunobu Andoh, Haruna Ui, Jung-Bum Lee, and Yasushi Kuraishi
  J Pharmacol Sci.   2009 ; 109 : 388-395
• Predominant Promotion by Tacrolimus of Chondrogenic Differentiation to Proliferating Chondrocytes
  Yukari Nakamura, Takeshi Takarada, Ayumi Kodama, Eiichi Hinoi, and Yukio Yoneda
  J Pharmacol Sci.   2009 ; 109 : 413-423
• The C-Terminal Region of Serotonin Transporter Is Important for Its Trafficking and Glycosylation
  Mariko Nobukuni, Hideki Mochizuki, Satoshi Okada, Nobuhisa Kameyama, Anna Tanaka, Hikaru Yamamoto, Taku Amano, Takahiro Seki, and Norio Sakai
  J Pharmacol Sci.   2009 ; 111 : 392-404

The JPS Prize 2009 Awards

• Markedly Reduced White Adipose Tissue and Increased Insulin Sensitivity in Adcyap1-Deficient Mice
  Shuhei Tomimoto, Tatsuya Ojika, Norihito Shintani, Hitoshi Hashimoto, Ken-ichi Hamagami, Kazuya Ikeda, Masanori Nakata, Toshihiko Yada, Yusuke Sakurai, Takeshi Shimada, Yoshiko Morita, Chie Ishida, and Akemichi Baba　　　　　　　　
  J Pharmacol Sci.   2008 ; 107 : 41-48
• Long-Lasting Anti-emetic Effect of T-2328, a Novel NK₁ Antagonist
  Yumi Watanabe, Masahito Okamoto, Taketoshi Ishii, Satomi Takatsuka, Hiroyuki Taniguchi, Masaaki Nagasaki, and Akira Saito
  J Pharmacol Sci.   2008 ; 107 : 151-158
• µ-Opioid Receptor Forms a Functional Heterodimer With Cannabinoid CB₁ Receptor: Electrophysiological and FRET Assay Analysis
  Minoru Hojo, Yuka Sudo, Yuko Ando, Koichiro Minami, Masafumi Takada, Takehiro Matsubara, Masato Kanaide, Kohtaro Taniyama, Koji Sumikawa, and Yasuhito Uezono
  J Pharmacol Sci.   2008 ; 108 : 308-319

The JPS Prize 2008 Awards

• Blockade of Leukotriene B₄ Signaling Pathway Induces Apoptosis and Suppresses Cell Proliferation in Colon Cancer
  Aya Ihara, Koichiro Wada, Masato Yoneda, Nobutaka Fujisawa, Hirokazu Takahashi, and Atsushi Nakajima　　　　　　　　
  J Pharmacol Sci.   2007 ; 103 : 24-32
• Stimulation of Histamine ₁ Receptor Up-Regulates Histamine H₁ Receptor Itself Through Activation of Receptor Gene Transcription
  Asish K. Das, Sachiho Yoshimura, Ryoko Mishima, Katsumi Fujimoto, Hiroyuki Mizuguchi, Shrabanti Dev, Yousuke Wakayama, Yoshiaki Kitamura, Shuhei Horio, Noriaki Takeda, and Hiroyuki Fukui
  J Pharmacol Sci.   2007 ; 103 : 374-382
• Membrane Stretch-Induced Activation of a TRPM4-Like Nonselective Cation Channel in Cerebral Artery Myocytes
  Hiromitsu Morita, Akira Honda, Ryuji Inoue, Yushi Ito, Kihachiro Abe, Mark T. Nelson, and Joseph E. Brayden
  J Pharmacol Sci.   2007 ; 103 :  417-426

The JPS Prize 2007 Awards

• Physiological Significance of Thromboxane A₂ Receptor Dimerization
  Masako Sasaki, Katsutoshi Miyosawa, Satoko Ohkubo and Norimichi Nakahata
  J Pharmacol Sci. 2006 ; 100 : 263-270
• Effects of Erythropoietin on Cardiac Remodeling After Myocardial Infarction
  Daisuke Nishiya, Takashi Omura, Kenei Shimada, Ryo Matsumoto, Takanori Kusuyama, Soichiro Enomoto, Hiroshi Iwao, Kazuhide Takeuchi, Junichi Yoshikawa and Minoru Yoshiyama
  J Pharmacol Sci. 2006 ; 101 : 31-39
• Heterotrimeric G Protein G_α13-Induced Induction of Cytokine mRNAs Through Two Distinct Pathways in Cardiac Fibroblasts
  Yuichi Nagamatsu, Motohiro Nishida, Naoya Onohara, Masashi Fukutomi, Yoshiko Maruyama, Hiroyuki Kobayashi, Yoji Sato and Hitoshi Kurose
  J Pharmacol Sci. 2006 ; 101 : 144-150

The JPS Prize 2006 Awards

• Increased Excretion of Urinary 20-HETE in Rats With Cyclosporine-Induced Nephrotoxicity
  Takayuki Seki, Tsuyoshi Ishimoto, Takanobu Sakurai, Yoshiko Yasuda, Kazuo Taniguchi, Mariko Doi, Mariko Sato, Richard J. Roman, and Noriyuki Miyata
  J Pharmacol Sci. 2005 ; 97 : 132-137
• Proteasome Inhibitors Protect Against Degeneration of Nigral Dopaminergic Neurons in Hemiparkinsonian Rats
  Masatoshi Inden, Jun-ichi Kondo, Yoshihisa Kitamura, Kazuyuki Takata, Kaneyasu Nishimura, Takashi Taniguchi, Hideyuki Sawada, and Shun Shimohama
  J Pharmacol Sci. 2005 ; 97 : 203-211

The JPS Prize 2005 Awards

• A Novel Method to Quantify Calcium Response Pattern and Oscillation Using Fura2 and Acridine Orange
  Mitsuhiro Morita, Jinichi Susuki, Takanori Moto, Chitose Higuchi, and Yoshihisa Kudo
  J Pharmacol Sci. 2004 ; 94 : 25 - 30
• Involvement of TRPM7 in Cell Growth as a Spontaneously Activated Ca²⁺ Entry Pathway in Human Retinoblastoma Cells
  Toyohisa Hanano, Yuji Hara, Juan Shi, Hiromitsu Morita, Chisato Umebayashi, Emiko Mori, Hideki Sumimoto, Yushi Ito, Yasuo Mori, and Ryuji Inoue
  J Pharmacol Sci. 2004 ; 95 : 403 - 419
• Angiogenesis In Vitro: Vascular Tube Formation From the Differentiation of Neural Stem Cells
  Kazuhiko Oishi, Akiko Kobayashi, Katsunori Fujii, Daisuke Kanehira, Yuko Ito, and Masaatsu K. Uchida
  J Pharmacol Sci. 2004 ; 96 : 208 - 218
  

The JPS Prize 2004 Awards

• Utilization of Knockout Mice to Examine the Potential Role of Gastric Histamine H2- Receptors in Menetrier’s Disease
  Toshiki Ogawa, Kazuhiko Maeda, Shunsuke Tonai, Takashi Kobayashi, Takeshi Watanabe, and Susumu Okabe
  J Pharmacol Sci. 2003；91：61−70.
  
• Orexin Receptor Type-1 Couples Exclusively to Pertussis Toxin-Insensitive G-Proteins, While Orexin Receptor Type-2 Couples to Both Pertussis Toxin-Sensitive and -Insensitive G-Proteins
  Yun Zhu，Yoshihiro Miwa, Akihiro Yamanaka, Toshihiko Yada, Megumi　Shibahara,
  Yoichiro Abe, Takeshi Sakurai, and Katsutoshi Goto
  J Pharmacol Sci. 2003；92：259−266.
  
• Evaluation of Human Peroxisome Proliferator-Activated Receptor(PPAR) Subtype Selectivityof a Variety of Anti-inflammatory Drugs Based on a Novel Assay for PPARδ(β)
  Hitoshi Kojo, Masao Fukagawa, Kaoru Tajima, Akiko Suzuki, Takao Fujimura, Ichiro Aramori, Ken-ichi Hayashi, and Shintaro Nishimura
  J Pharmacol Sci. 2003；93：347-355.

The JJP Prize 2003 Awards

• Novel Mutations in C-terminal Channel Region of the Ryanodine Receptor in Malignant Hyperthermia Patients
  Hideto Oyamada*, Keiko Oguchi*, Naoto Saitoh*, Toshiko Yamazawa, Kenzo Hirose, Yoko Kawana, Kazunao Wakatsuki, Katsuji Oguchi, Megumi Tagami, Kazuo Hanaoka, Makoto Endo and Masamitsu Iino
  Jpn. J. Pharmacol. 88, 159-166 (2002)
  *The first three authors equally contributed to this work.
• Contractile Responses and Myosin Phosphorylation in Reconstituted Fibers of Smooth Muscle Cells From the Rat Cerebral Artery
  Kazuhiko Oishi, Yoshitaka Takatoh, Jianjun Bao and Masaatsu K. Uchida
  Jpn. J. Pharmacol. 90, 36-50 (2002)

The JJP Prize 2002 Awards

• Molecular Mechanisms for a₂-Adrenoceptor-Mediated Regulation of Synoviocyte Population
  Katsuyuki Mishima, Hitomi Otani, Takatoshi Tanabe, Hiroshi Kawasaki, Akihiro Oshiro, Naoaki Saito, Ryokei Ogawa and Chiyoko Inagaki
  Jpn. J. Pharmacol. 85, 214 - 226 (2001)
• Ca²⁺-Images of Smooth Muscle Cells and Endothelial Cells in One Confocal Plane in Femoral Artery Segments of the Rat
  Yoshiaki Ohi, Nobuhiko Takai, Katsuhiko Muraki, Minoru Watanabe and Yuji Imaizumi
  Jpn. J. Pharmacol. 86, 106 - 113 (2001)
• Adenylate Cyclase / Protein Kinase A Signaling Pathway Enhances Angiogenesis Through Induction of Vascular Endothelial Growth Factor In Vivo
  Hideki Amano, Kao Ando, Satoshi Minamida, Izumi Hayashi, Michiko Ogino, Shohei Yamashina, Hirokuni Yoshimura and Masataka Majima
  Jpn. J. Pharmacol. 87, 181 - 188 (2001)

The JJP Prize 2001 Awards

• Endomorphin-1 Discriminates the m-Opioid Receptor From the d- and k-Opioid Receptors by Recognizing the Difference in Multiple Regions
  Soichiro Ide, Kyoko Sakano, Takahiro Seki, Shinichiro Awamura, Masabumi Minami and Masamichi Satoh
  Jpn. J. Pharmacol. 83, 306 - 311 (2000)
• Pharmacological and Immunohistochemical Characterization of a Mouse Model of Acute Herpetic Pain
  Ichiro Takasaki, Tsugunobu Andoh, Makoto Nitta, Hiroki Takahata, Hideo Nemoto, Kimiyasu Shiraki, Hiroshi Nojima and Ysasushi Kuraishi
  Jpn. J. Pharmacol. 83, 319 - 326 (2000)
• Calcium Signaling and c-Fos Gene Expression via M₃ Muscarinic Acetylcholine Receptors in Human T- and B-Cells
  Takeshi Fujii and Koichiro Kawashima
  Jpn. J. Pharmacol. 84, 124 - 132 (2000)

The JJP Prize 2000 Awards

• Long-Term Treatment With Angiotensin Converting Enzyme Inhibitor Restores Reduced Calcitonin Gene-Related Peptide-Containing Vasodilator Nerve Function in Mesenteric Artery of Spontaneously Hypertensive Rats
  Hiromu Kawasaki, Masatoshi Okazaki, Akira Nakatsuma,
  Yuichi Mimaki, Hiroaki Araki and Yutaka Gomita
  Jpn. J. Pharmacol. 79, 221 - 229 (1999)
• Propofol Inhibits Muscarinic Acetylcholine Receptor-Mediated Signal Transduction in Xenopus Oocytes Expressing the Rat M1 Receptor
  Yoshihisa Nagase, Muneshige Kaibara, Yasuhito Uezono,
  Futoshi Izumi, Koji Sumikawa and Kohtaro Taniyama
  Jpn. J. Pharmacol. 79, 319 - 325 (1999)
• Natriuretic Peptide Receptors, NPR-A and NPR-B, in Cultured Rabbit Retinal Pigment Epithelium Cells
  Yoshito Fujiseki, Kyoko Omori, Koichiro Omori, Yoshito Mikami, Junko Suzukawa, Gaku Okugawa, Masanobu Uyama and
  Chiyoko Inagaki
  Jpn. J. Pharmacol. 79, 359 - 368 (1999)

The JJP Prize 1999 Awards

• Vascular alpha1-Adrenoceptor Subtype Selectivity and alpha1-Blocker Induced Orthostatic Hypotension
  Hitoshi Take, Katsushi Shibata, Takeo Awaji, Akira Hirasawa, Ichiro Ikegaki, Toshio Asano, Tatsuyuki Takada and Gozoh Tsujimoto
  Jpn. J. Pharmacol. 77, 61-70 (1998)
• Co-culture With the Striatum Attenuates N-Methyl-D-aspartate Cytotoxicity in Dopaminergic Neurons of Rat Mesencephalic Slice Cultures
  Takehiko Maeda, Masakazu Ibi, Seiichiro Shimazu and Akinori Akaike
  Jpn. J. Pharmacol. 77, 161-167 (1998)
• Protective Effect of Talipexole on MPTP-Treated Planarian, a Unique Parkinsonian Worm Model
  Yoshihisa Kitamura, Jun-ichi Kakimura and Takashi Taniguchi
  Jpn. J. Pharmacol. 78, 23-29 (1998)

The JJP Prize 1998 Awards

• Role of Endogenous Basic Fibroblast Growth Factor in the Healing of Gastric Ulcers in Rats
  Hiroshi Satoh, Akio Shino, Fumihiko Sato, Shoichi Asano, Izumi Murakami, Nobuhiro Inatomi, Hideaki Nagaya, Koichi Kato, Sandor Szabo and Judah Folkman
  Jpn. J. Pharmacol. 73, 59-71 (1997)
• Significant Roles of Inducible Cyclooxygenase (COX)-2 in Angiogenesis in Rat Sponge Implants
  Masataka Majima, Masako Isono, Yasuhiro Ikeda, Izumi Hayashi, Ko Hatanaka, Yoshiteru Harada, Osamu Katsumata, Shohei Yamashina, Makoto Katori and Shouzo Yamamoto
  Jpn. J. Pharmacol. 75, 105-114 (1997)
• Basic Fibroblast Growth Factor and Brain-Derived Neurotrophic Factor Promote Survival and Neuronal Circuit Formation in Organotypic Hippocampal Culture
  Yasuhiro Nakagami, Hiroshi Saito and Norio Matsuki
  Jpn. J. Pharmacol. 75, 319-326 (1997)

The JJP Prize 1997 Awards

• Restricted Propagation of Cytoplasmic Ca2+ Oscillation into the Nucleus in Guinea Pig Cardiac Myocytes as Revealed by Rapid Scanning Confocal Microscopy and Indo-1
  Hikaru Tanaka, Toru Kawanishi, Yoshimitsu Kato, Ryu Nakamura and Koki Shigenobu
  Jpn. J. Pharmacol. 70, 235-242 (1996)
• Effects of Stilbene Derivatives SITS and DIDS on Development of Intracellular Acidosis during Ischemia in Isolated Guinea Pig Ventricular Papillary Muscle In Vitro
  Zhong-Fang Lai, Jie Liu and Katsuhide Nishi
  Jpn. J. Pharmacol. 72, 161-174 (1996)
• Electrophysiological and Pharmacological Characteristics of Ionotropic
  Glutamate Receptors in Medial Vestibular Nucleus Neurons:
  A Whole Cell Patch Clamp Study in Acutely Dissociated Neurons
  Norio Sakai, Hisamitsu Ujihara, Kumatoshi Ishihara, Masashi Sasa and Chikako Tanaka
  Jpn. J. Pharmacol. 72, 335-346 (1996)

The JJP Prize 1996 Awards

• Adrenergic Receptor-Mediated Cl^- Transport in Rabbit Corneal Endothelial Cells
  Tohru Yasukura, Masafumi Inoue, Takao Irie, Mitsuyoshi Hara,
  Yoshito Mikami, Xun-ting Zeng, Toshiko Mikami, Kyoko Omori,
  Akio Minato, Masanobu Uyama and Chiyoko Inagaki
  Jpn. J. Pharmacol. 67, 315-320 (1995)
• Calcitonin Gene-Related Peptide Mediated Neurogenic Vasorelaxation in the Isolated Canine Lingual Artery
  Dai Kobayashi, Kazuo Todoki, Satoru Ozono and Eiichiro Okabe
  Jpn. J. Pharmacol. 67, 329-339 (1995)
• Mechanism and Properties of Inhibition of Purified Rat Brain Adenylate Cyclase by G Protein beta-gamma-Subunits
  Keiichi Enomoto, Masako Takano, Shunji Ariyoshi
  and Takeo Asakawa
  Jpn. J. Pharmacol. 69, 239-250 (1995)

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