The JPS Prize
The JPS Prize 2012 Awards
- Bepridil Facilitates Early Termination of Spiral-Wave Reentry in Two-Dimensional Cardiac Muscle Through an Increase of Intercellular Electrical Coupling
Hiroki Takanari, Haruo Honjo, Yoshio Takemoto, Tomoyuki Suzuki, Sara Kato, Masahide Harada, Yusuke Okuno, Takashi Ashihara, Tobias Opthof, Ichiro Sakuma, Kaichiro Kamiya and Itsuo Kodama
J Pharmacol Sci. 2011 ; 115 : 15-26
- Dual Signaling Pathways of Arterial Constriction by Extracellular Uridine 5′-Triphosphate in the Rat
Megumi Sugihara, Hiromitsu Morita, Miho Matsuda, Hisanori Umebayashi, Shunichi Kajioka, Shinichi Ito, Motohiro Nishida, Ryosuke Inoue, Toshiko Futatsuki, Jun Yamazaki, Yasuo Mori, Ryuji Inoue, Yushi Ito, Kihachiro Abe and Masato Hirata
J Pharmacol Sci. 2011 ; 115 : 293-308
- Electrophysiological Characterization of Cardiomyocytes Derived From Human Induced Pluripotent Stem Cells
Masaki Honda, Jumpei Kiyokawa, Mitsuyasu Tabo and Tomoaki Inoue
J Pharmacol Sci. 2011 ; 117 : 149-159
The JPS Prize 2011 Awards
- Mechanism Underlying the Protective Effect of Tempol and Nω-Nitro-L-arginine Methyl Ester on Acoustic Injury: Possible Involvement of c-Jun N-Terminal Kinase Pathway and Connexin26 in the Cochlear Spiral Ligament
Reiko Nagashima, Taro Yamaguchi, Hajime Tanaka, and Kiyokazu Ogita
J Pharmacol Sci. 2010 ; 114 : 50-62
- Computational Analysis of the Effects of Antineoplastic Agents on Axonal Transport
Yoshio Goshima, Hiroshi Usui, Takahito Shiozawa, Tomonobu Hida, Satoshi Kuraoka, Sayumi Takeshita, Naoya Yamashita, Yasushi Ichikawa, Yoshinori Kamiya, Takahisa Gotoh, and Toshiyuki Gotoh
J Pharmacol Sci. 2010 ; 114 : 168-179
- Antipsychotic Potential of Quinazoline ErbB1 Inhibitors in a Schizophrenia Model Established With Neonatal Hippocampal Lesioning
Makoto Mizuno, Yuriko Iwakura, Masako Shibuya, Yingjun Zheng, Takeyoshi Eda, Taisuke Kato, Yohei Takasu, and Hiroyuki Nawa
J Pharmacol Sci. 2010 ; 114 : 320-331
The JPS Prize 2010 Awards
- Involvement of Tryptase and Proteinase-Activated Receptor-2 in Spontaneous
Itch-Associated Response in Mice With Atopy-like Dermatitis
Kenichiro Tsujii, Tsugunobu Andoh, Haruna Ui, Jung-Bum Lee, and Yasushi Kuraishi
J Pharmacol Sci. 2009 ; 109 : 388-395
- Predominant Promotion by Tacrolimus of Chondrogenic Differentiation to Proliferating
Chondrocytes
Yukari Nakamura, Takeshi Takarada, Ayumi Kodama, Eiichi Hinoi, and Yukio Yoneda
J Pharmacol Sci. 2009 ; 109 : 413-423
- The C-Terminal Region of Serotonin Transporter Is Important for Its Trafficking
and Glycosylation
Mariko Nobukuni, Hideki Mochizuki, Satoshi Okada, Nobuhisa Kameyama,
Anna Tanaka, Hikaru Yamamoto, Taku Amano, Takahiro Seki, and Norio Sakai
J Pharmacol Sci. 2009 ; 111 : 392-404
The JPS Prize 2009 Awards
- Markedly Reduced White Adipose Tissue and Increased Insulin Sensitivity in Adcyap1-Deficient Mice
Shuhei Tomimoto, Tatsuya Ojika, Norihito Shintani, Hitoshi Hashimoto, Ken-ichi
Hamagami, Kazuya Ikeda, Masanori Nakata, Toshihiko Yada, Yusuke Sakurai, Takeshi
Shimada, Yoshiko Morita, Chie Ishida, and Akemichi Baba
J Pharmacol Sci. 2008 ; 107 : 41-48
- Long-Lasting Anti-emetic Effect of T-2328, a Novel NK1 Antagonist
Yumi Watanabe, Masahito Okamoto, Taketoshi Ishii, Satomi Takatsuka, Hiroyuki
Taniguchi, Masaaki Nagasaki, and Akira Saito
J Pharmacol Sci. 2008 ; 107 : 151-158
- µ-Opioid Receptor Forms a Functional Heterodimer With Cannabinoid CB1 Receptor:
Electrophysiological and FRET Assay Analysis
Minoru Hojo, Yuka Sudo, Yuko Ando, Koichiro Minami, Masafumi Takada,
Takehiro Matsubara, Masato Kanaide, Kohtaro Taniyama, Koji Sumikawa, and Yasuhito
Uezono
J Pharmacol Sci. 2008 ; 108 : 308-319
The JPS Prize 2008 Awards
- Blockade of Leukotriene B4 Signaling Pathway Induces Apoptosis and Suppresses Cell Proliferation in Colon Cancer
Aya Ihara, Koichiro Wada, Masato Yoneda, Nobutaka Fujisawa, Hirokazu Takahashi,
and Atsushi Nakajima
J Pharmacol Sci. 2007 ; 103 : 24-32
- Stimulation of Histamine 1 Receptor Up-Regulates Histamine H1 Receptor Itself Through Activation of Receptor Gene Transcription
Asish K. Das, Sachiho Yoshimura, Ryoko Mishima, Katsumi Fujimoto, Hiroyuki
Mizuguchi, Shrabanti Dev, Yousuke Wakayama, Yoshiaki Kitamura, Shuhei Horio,
Noriaki Takeda, and Hiroyuki Fukui
J Pharmacol Sci. 2007 ; 103 : 374-382
- Membrane Stretch-Induced Activation of a TRPM4-Like Nonselective Cation Channel in Cerebral Artery Myocytes
Hiromitsu Morita, Akira Honda, Ryuji Inoue, Yushi Ito, Kihachiro
Abe, Mark T. Nelson, and Joseph E. Brayden
J Pharmacol Sci. 2007 ; 103 : 417-426
The JPS Prize 2007 Awards
- Physiological Significance of Thromboxane A2 Receptor Dimerization
Masako Sasaki, Katsutoshi Miyosawa, Satoko Ohkubo and Norimichi Nakahata
J Pharmacol Sci. 2006 ; 100 : 263-270
-
Effects of Erythropoietin on Cardiac Remodeling After Myocardial Infarction
Daisuke Nishiya, Takashi Omura, Kenei Shimada, Ryo Matsumoto, Takanori Kusuyama,
Soichiro Enomoto, Hiroshi Iwao, Kazuhide Takeuchi, Junichi Yoshikawa and Minoru
Yoshiyama
J Pharmacol Sci. 2006 ; 101 : 31-39
- Heterotrimeric G Protein Gα13-Induced Induction of Cytokine mRNAs Through Two
Distinct Pathways in Cardiac Fibroblasts
Yuichi Nagamatsu, Motohiro Nishida, Naoya Onohara, Masashi Fukutomi, Yoshiko
Maruyama, Hiroyuki Kobayashi, Yoji Sato and Hitoshi Kurose
J Pharmacol Sci. 2006 ; 101 : 144-150
The JPS Prize 2006 Awards
- Increased
Excretion of Urinary 20-HETE in Rats With Cyclosporine-Induced Nephrotoxicity
Takayuki Seki, Tsuyoshi Ishimoto, Takanobu Sakurai, Yoshiko Yasuda, Kazuo
Taniguchi, Mariko Doi, Mariko Sato, Richard J. Roman, and Noriyuki Miyata
J Pharmacol Sci. 2005 ; 97 : 132-137
-
Proteasome Inhibitors Protect Against Degeneration of Nigral Dopaminergic
Neurons in Hemiparkinsonian Rats
Masatoshi Inden, Jun-ichi Kondo, Yoshihisa Kitamura, Kazuyuki Takata, Kaneyasu
Nishimura, Takashi Taniguchi, Hideyuki Sawada, and Shun Shimohama
J Pharmacol Sci. 2005 ; 97 : 203-211
The JPS Prize 2005 Awards
- A
Novel Method to Quantify Calcium Response Pattern and Oscillation Using Fura2
and Acridine Orange
Mitsuhiro Morita, Jinichi Susuki, Takanori Moto, Chitose Higuchi, and Yoshihisa
Kudo
J Pharmacol Sci. 2004 ; 94 : 25 - 30
- Involvement
of TRPM7 in Cell Growth as a Spontaneously Activated Ca2+ Entry
Pathway in Human Retinoblastoma Cells
Toyohisa Hanano, Yuji Hara, Juan Shi, Hiromitsu Morita, Chisato Umebayashi,
Emiko Mori, Hideki Sumimoto, Yushi Ito, Yasuo Mori, and Ryuji Inoue
J Pharmacol Sci. 2004 ; 95 : 403 - 419
- Angiogenesis
In Vitro: Vascular Tube Formation From the Differentiation of Neural Stem
Cells
Kazuhiko Oishi, Akiko Kobayashi, Katsunori Fujii, Daisuke Kanehira, Yuko Ito,
and Masaatsu K. Uchida
J Pharmacol Sci. 2004 ; 96 : 208 - 218
The JPS Prize 2004 Awards
- Utilization
of Knockout Mice to Examine the Potential Role of Gastric Histamine H2-
Receptors in Menetrier’s Disease
Toshiki Ogawa, Kazuhiko Maeda, Shunsuke Tonai, Takashi Kobayashi, Takeshi
Watanabe, and Susumu Okabe
J Pharmacol Sci. 2003；91：61－70.
- Orexin
Receptor Type-1 Couples Exclusively to Pertussis Toxin-Insensitive G-Proteins,
While Orexin Receptor Type-2 Couples to Both Pertussis Toxin-Sensitive
and -Insensitive G-Proteins
Yun Zhu，Yoshihiro Miwa, Akihiro Yamanaka, Toshihiko Yada, Megumi Shibahara,
Yoichiro Abe, Takeshi Sakurai, and Katsutoshi Goto
J Pharmacol Sci. 2003；92：259－266.
- Evaluation
of Human Peroxisome Proliferator-Activated Receptor(PPAR) Subtype Selectivityof
a Variety of Anti-inflammatory Drugs Based on a Novel Assay for PPARδ(β)
Hitoshi Kojo, Masao Fukagawa, Kaoru Tajima, Akiko Suzuki, Takao Fujimura,
Ichiro Aramori, Ken-ichi Hayashi, and Shintaro Nishimura
J Pharmacol Sci. 2003；93：347-355.
The JJP Prize 2003 Awards
- Novel
Mutations in C-terminal Channel Region of the Ryanodine Receptor in Malignant
Hyperthermia Patients
Hideto Oyamada*, Keiko Oguchi*, Naoto Saitoh*, Toshiko Yamazawa, Kenzo
Hirose, Yoko Kawana, Kazunao Wakatsuki, Katsuji Oguchi, Megumi Tagami,
Kazuo Hanaoka, Makoto Endo and Masamitsu Iino
Jpn. J. Pharmacol. 88, 159-166 (2002)
*The first three authors equally contributed to this work.
- Contractile
Responses and Myosin Phosphorylation in Reconstituted Fibers of Smooth
Muscle Cells From the Rat Cerebral Artery
Kazuhiko Oishi, Yoshitaka Takatoh, Jianjun Bao and Masaatsu K. Uchida
Jpn. J. Pharmacol. 90, 36-50 (2002)
The JJP Prize 2002 Awards
- Molecular
Mechanisms for a2-Adrenoceptor-Mediated Regulation of Synoviocyte
Population
Katsuyuki Mishima, Hitomi Otani, Takatoshi Tanabe, Hiroshi Kawasaki, Akihiro
Oshiro, Naoaki Saito, Ryokei Ogawa and Chiyoko Inagaki
Jpn. J. Pharmacol. 85, 214 - 226 (2001)
- Ca2+-Images
of Smooth Muscle Cells and Endothelial Cells in One Confocal Plane in
Femoral Artery Segments of the Rat
Yoshiaki Ohi, Nobuhiko Takai, Katsuhiko Muraki, Minoru Watanabe and Yuji
Imaizumi
Jpn. J. Pharmacol. 86, 106 - 113 (2001)
- Adenylate
Cyclase / Protein Kinase A Signaling Pathway Enhances Angiogenesis Through
Induction of Vascular Endothelial Growth Factor In Vivo
Hideki Amano, Kao Ando, Satoshi Minamida, Izumi Hayashi, Michiko Ogino,
Shohei Yamashina, Hirokuni Yoshimura and Masataka Majima
Jpn. J. Pharmacol. 87, 181 - 188 (2001)
The JJP Prize 2001 Awards
- Endomorphin-1
Discriminates the m-Opioid Receptor From the
d- and k-Opioid Receptors
by Recognizing the Difference in Multiple Regions
Soichiro Ide, Kyoko Sakano, Takahiro Seki, Shinichiro Awamura, Masabumi
Minami and Masamichi Satoh
Jpn. J. Pharmacol. 83, 306 - 311 (2000)
- Pharmacological
and Immunohistochemical Characterization of a Mouse Model of Acute Herpetic
Pain
Ichiro Takasaki, Tsugunobu Andoh, Makoto Nitta, Hiroki Takahata, Hideo
Nemoto, Kimiyasu Shiraki, Hiroshi Nojima and Ysasushi Kuraishi
Jpn. J. Pharmacol. 83, 319 - 326 (2000)
- Calcium
Signaling and c-Fos Gene Expression via M3 Muscarinic Acetylcholine
Receptors in Human T- and B-Cells
Takeshi Fujii and Koichiro Kawashima
Jpn. J. Pharmacol. 84, 124 - 132 (2000)
The JJP Prize 2000 Awards
- Long-Term
Treatment With Angiotensin Converting Enzyme Inhibitor Restores Reduced
Calcitonin Gene-Related Peptide-Containing Vasodilator Nerve Function
in Mesenteric Artery of Spontaneously Hypertensive Rats
Hiromu Kawasaki, Masatoshi Okazaki, Akira Nakatsuma,
Yuichi Mimaki, Hiroaki Araki and Yutaka Gomita
Jpn. J. Pharmacol. 79, 221 - 229 (1999)
- Propofol
Inhibits Muscarinic Acetylcholine Receptor-Mediated Signal Transduction
in Xenopus Oocytes Expressing the Rat M1 Receptor
Yoshihisa Nagase, Muneshige Kaibara, Yasuhito Uezono,
Futoshi Izumi, Koji Sumikawa and Kohtaro Taniyama
Jpn. J. Pharmacol. 79, 319 - 325 (1999)
- Natriuretic
Peptide Receptors, NPR-A and NPR-B, in Cultured Rabbit Retinal Pigment
Epithelium Cells
Yoshito Fujiseki, Kyoko Omori, Koichiro Omori, Yoshito Mikami, Junko Suzukawa,
Gaku Okugawa, Masanobu Uyama and
Chiyoko Inagaki
Jpn. J. Pharmacol. 79, 359 - 368 (1999)
The JJP Prize 1999 Awards
- Vascular
alpha1-Adrenoceptor Subtype Selectivity and alpha1-Blocker Induced Orthostatic
Hypotension
Hitoshi Take, Katsushi Shibata, Takeo Awaji, Akira Hirasawa, Ichiro Ikegaki,
Toshio Asano, Tatsuyuki Takada and Gozoh Tsujimoto
Jpn. J. Pharmacol. 77, 61-70 (1998)
- Co-culture
With the Striatum Attenuates N-Methyl-D-aspartate Cytotoxicity in Dopaminergic
Neurons of Rat Mesencephalic Slice Cultures
Takehiko Maeda, Masakazu Ibi, Seiichiro Shimazu and Akinori Akaike
Jpn. J. Pharmacol. 77, 161-167 (1998)
- Protective
Effect of Talipexole on MPTP-Treated Planarian, a Unique Parkinsonian
Worm Model
Yoshihisa Kitamura, Jun-ichi Kakimura and Takashi Taniguchi
Jpn. J. Pharmacol. 78, 23-29 (1998)
The JJP Prize 1998 Awards
-
Role of Endogenous
Basic Fibroblast Growth Factor in the Healing of Gastric Ulcers in Rats
Hiroshi Satoh, Akio Shino, Fumihiko Sato, Shoichi Asano, Izumi Murakami,
Nobuhiro Inatomi, Hideaki Nagaya, Koichi Kato, Sandor Szabo and Judah
Folkman
Jpn. J. Pharmacol. 73, 59-71 (1997)
- Significant Roles of
Inducible Cyclooxygenase (COX)-2 in Angiogenesis in Rat Sponge Implants
Masataka Majima, Masako Isono, Yasuhiro Ikeda, Izumi Hayashi, Ko Hatanaka,
Yoshiteru Harada, Osamu Katsumata, Shohei Yamashina, Makoto Katori and
Shouzo Yamamoto
Jpn. J. Pharmacol. 75, 105-114 (1997)
- Basic Fibroblast Growth
Factor and Brain-Derived Neurotrophic Factor Promote Survival and Neuronal
Circuit Formation in Organotypic Hippocampal Culture
Yasuhiro Nakagami, Hiroshi Saito and Norio Matsuki
Jpn. J. Pharmacol. 75, 319-326 (1997)
The JJP Prize 1997 Awards
- Restricted Propagation
of Cytoplasmic Ca2+ Oscillation into the Nucleus in Guinea Pig Cardiac
Myocytes as Revealed by Rapid Scanning Confocal Microscopy and Indo-1
Hikaru Tanaka, Toru Kawanishi, Yoshimitsu Kato, Ryu Nakamura and Koki
Shigenobu
Jpn. J. Pharmacol. 70, 235-242 (1996)
- Effects of Stilbene
Derivatives SITS and DIDS on Development of Intracellular
Acidosis during Ischemia in Isolated Guinea Pig Ventricular
Papillary Muscle In Vitro
Zhong-Fang Lai, Jie Liu and Katsuhide Nishi
Jpn. J. Pharmacol. 72, 161-174 (1996)
- Electrophysiological
and Pharmacological Characteristics of Ionotropic
Glutamate Receptors in Medial Vestibular Nucleus Neurons:
A Whole Cell Patch Clamp Study in Acutely Dissociated Neurons
Norio Sakai, Hisamitsu Ujihara, Kumatoshi Ishihara, Masashi Sasa and Chikako
Tanaka
Jpn. J. Pharmacol. 72, 335-346 (1996)
The JJP Prize 1996 Awards
- Adrenergic Receptor-Mediated Cl- Transport in Rabbit Corneal
Endothelial Cells
Tohru Yasukura, Masafumi Inoue, Takao Irie, Mitsuyoshi Hara,
Yoshito Mikami, Xun-ting Zeng, Toshiko Mikami, Kyoko Omori,
Akio Minato, Masanobu Uyama and Chiyoko Inagaki
Jpn. J. Pharmacol. 67, 315-320 (1995)
- Calcitonin Gene-Related Peptide Mediated Neurogenic Vasorelaxation
in the Isolated Canine Lingual Artery
Dai Kobayashi, Kazuo Todoki, Satoru Ozono and Eiichiro Okabe
Jpn. J. Pharmacol. 67, 329-339 (1995)
- Mechanism and Properties of Inhibition of Purified Rat Brain Adenylate
Cyclase by G Protein beta-gamma-Subunits
Keiichi Enomoto, Masako Takano, Shunji Ariyoshi
and Takeo Asakawa
Jpn. J. Pharmacol. 69, 239-250 (1995)
